M K Kuhner

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi Maximum likelihood estimation of population growth rates based on the coalescent
    M K Kuhner
    Department of Genetics, University of Washington, Seattle, Washington 98195, USA
    Genetics 149:429-34. 1998
  2. ncbi Usefulness of single nucleotide polymorphism data for estimating population parameters
    M K Kuhner
    Department of Genetics, University of Washington, Seattle, Washington 98195 7360, USA
    Genetics 156:439-47. 2000
  3. ncbi Sampling among haplotype resolutions in a coalescent-based genealogy sampler
    M K Kuhner
    Department of Genetics, University of Washington, Seattle 98195 7360, USA
    Genet Epidemiol 19:S15-21. 2000
  4. ncbi Maximum likelihood estimation of recombination rates from population data
    M K Kuhner
    Department of Genetics, University of Washington, Seattle, Washington 98195, USA
    Genetics 156:1393-401. 2000

Detail Information

Publications4

  1. ncbi Maximum likelihood estimation of population growth rates based on the coalescent
    M K Kuhner
    Department of Genetics, University of Washington, Seattle, Washington 98195, USA
    Genetics 149:429-34. 1998
    ..Sampling additional unlinked loci is much more effective in reducing the bias than increasing the number or length of sequences from the same locus...
  2. ncbi Usefulness of single nucleotide polymorphism data for estimating population parameters
    M K Kuhner
    Department of Genetics, University of Washington, Seattle, Washington 98195 7360, USA
    Genetics 156:439-47. 2000
    ..Researchers collecting SNPs should collect and preserve information about the method of ascertainment so that the data can be accurately analyzed...
  3. ncbi Sampling among haplotype resolutions in a coalescent-based genealogy sampler
    M K Kuhner
    Department of Genetics, University of Washington, Seattle 98195 7360, USA
    Genet Epidemiol 19:S15-21. 2000
    ..The straightforward haplotype sampler does not mix well; heating approaches can greatly improve its performance...
  4. ncbi Maximum likelihood estimation of recombination rates from population data
    M K Kuhner
    Department of Genetics, University of Washington, Seattle, Washington 98195, USA
    Genetics 156:1393-401. 2000
    ..However, when both Theta and r are relatively low, very long sequences are needed to estimate r accurately, and the estimates tend to be biased upward. We apply this method to data from the human lipoprotein lipase locus...