Research Topics
| I KuboSummaryAffiliation: University of California Country: USA Publications
| Collaborators
|
Detail Information
Publications
ent-Isopimarane diterpenoids of the leaves from Rabdosia forrestiiI Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720 3112, USA
Fitoterapia 74:643-9. 2003..The structures were established on the basis of NMR spectroscopic analysis and of the modified Mosher's (1H) method...- Anti-Salmonella activity of (2E)-alkenalsI Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720 3112, USA
J Appl Microbiol 96:693-9. 2004..This study investigated the effect of a series of naturally occurring aliphatic (2E)-alkenals against Salmonella choleraesuis subsp. choleraesuis ATCC 35640 and evaluated their antibacterial action... - Antibacterial activity of akyl gallates against Bacillus subtilisIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
J Agric Food Chem 52:1072-6. 2004..The antibacterial activity of alkyl gallates likely comes at least in part from their ability to inhibit the membrane respiratory chain but is not due to the prooxidant action... - Antibacterial activity of coriander volatile compounds against Salmonella choleraesuisIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
J Agric Food Chem 52:3329-32. 2004..The time-kill curve study showed that these alpha,beta-unsaturated aldehydes are bactericidal against S. choleraesuis at any growth stage and that their bactericidal action comes in part from the ability to act as nonionic surfactants... - Modes of antifungal action of (2E)-alkenals against Saccharomyces cerevisiaeIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
J Agric Food Chem 51:3951-7. 2003..Hence, the antifungal activity of (2E)-alkenals is mediated by biophysical processes, and the maximum activity can be obtained when the balance between the hydrophilic and hydrophobic portions becomes the most appropriate... - Oxidation products of quercetin catalyzed by mushroom tyrosinaseIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720 3112, USA
Bioorg Med Chem 12:5343-7. 2004..Fisetin, which lacks the C-5 hydroxyl group, was also oxidized but the rate of oxidation was faster than that of quercetin, indicating that the C-5 hydroxyl group is not essential but is associated with the activity... - Molecular design of multifunctional antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA)Isao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720 3112, USA
Bioorg Med Chem 11:4255-62. 2003..The length of the alkyl chain is not a major contributor but is related to the activity... - Methyl p-coumarate, a melanin formation inhibitor in B16 mouse melanoma cellsIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720 3112, USA
Bioorg Med Chem 12:5349-54. 2004..01 mM) of L-3,4-dihydroxyphenylalanine (L-DOPA) became available as a co-factor. Methyl p-coumarate significantly suppressed the melanin formation in B16 mouse melanoma cells, whereas p-coumaric acid did not show this activity... - Effect of EDTA alone and in combination with polygodial on the growth of Saccharomyces cerevisiaeIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
J Agric Food Chem 53:1818-22. 2005..Once inside the cells, EDTA forms chelation with divalent metals such as Mg(2+) and Ca(2+), which are required by various essential enzymes... - 2-Hydroxy-4-methoxybenzaldehyde: a potent tyrosinase inhibitor from African medicinal plantsI Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, USA
Planta Med 65:19-22. 1999..Based on finding this potent tyrosinase inhibitor, various related analogues were also tested in order to gain new insights into their inhibitory functions on a molecular basis... - Anti-MRSA activity of alkyl gallatesIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720 3112, USA
Bioorg Med Chem Lett 12:113-6. 2002..This bactericidal activity comes in part from its ability to inhibit respiratory electron transport systems. The length of the alkyl chain is not a major contributor but plays an important role in eliciting the activity... - Antibacterial activity of anacardic acid and totarol, alone and in combination with methicillin, against methicillin-resistant Staphylococcus aureusH Muroi
Department of Environmental Science, Policy and Management, University of California, Berkeley 94720 3112, USA
J Appl Bacteriol 80:387-94. 1996..The time-kill curves demonstrated synergistic bactericidal activities for these combinations... - Flavonols from Heterotheca inuloides: tyrosinase inhibitory activity and structural criteriaI Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley 94720 3112, USA
Bioorg Med Chem 8:1749-55. 2000..Kaempferol neither acts as a cofactor nor inhibits monophenolase activity. However, these three flavonols are common to inhibit diphenolase activity by chelating copper in the enzyme... - Antifungal mechanism of polygodialI Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720 3112, USA
J Agric Food Chem 49:1607-11. 2001..However, the potent antifungal activity of polygodial results from its multiple functions... - Molecular design of antibrowning agentsI Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
J Agric Food Chem 48:1393-9. 2000..The effects of side-chain length of gallates in relation to their antibrowning activity are studied... - Tyrosinase inhibitors from Anacardium occidentale fruitsI Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley 94720
J Nat Prod 57:545-51. 1994.... - Anethole, a potential antimicrobial synergist, converts a fungistatic dodecanol to a fungicidal agentKen ichi Fujita
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
Phytother Res 21:47-51. 2007..On the other hand, anethole completely restricted the recovery of cell viability. Therefore the expression of the synergistic effect was probably due to a blockade of the recovery process from dodecanol-induced stress... - Effects of salicylic acid on mushroom tyrosinase and B16 melanoma cellsSadaaki Tamura
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3114, USA
Z Naturforsch C 62:227-33. 2007..Neither acid showed noticeable effects on cultured murine B16-F10 melanoma cells except weak cytotoxicity... - Antifungal activity of octyl gallate: structural criteria and mode of actionI Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley 94720 3112, USA
Bioorg Med Chem Lett 11:347-50. 2001..The length of the alkyl chain is not a major contributor but plays an important role in eliciting the activity... - Identification of oxidation product of arbutin in mushroom tyrosinase assay systemKen ichi Nihei
Department of Environmental Science, Policy and Management, University of California, CA 94720-3112, Berkeley, USA
Bioorg Med Chem Lett 13:2409-12. 2003..A significant enzymatic product was identified as 3,4-dihydroxyphenyl-O-beta-D-glucopyranoside by NMR and MS experiments... - Flavonols from saffron flower: tyrosinase inhibitory activity and inhibition mechanismI Kubo
Department of Environmental Science, University of California, Berkeley, California 94720 3112, USA
J Agric Food Chem 47:4121-5. 1999..This copper chelation mechanism can be applicable for all of the flavonols as long as their 3-hydroxyl group is free. However, quercetin, kaempferol, and galangin each affect the oxidation of L-tyrosine in somewhat different ways... 
Effects of phenolic compounds isolated from Rabdosia japonica on B16-F10 melanoma cellsTeruhiko Nitoda
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
Phytother Res 22:867-72. 2008..5 microg/mL). As the cells were cultured with this flavone, melanin production was not suppressed, but rather enhanced. Quercetin isolated from the same source exhibited similar activities, but rutin showed neither activity...- Naturally occurring anti-Salmonella agentsI Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
J Agric Food Chem 49:5750-4. 2001..However, they showed different effects on the growth of S. choleraesuis. The combination of polygodial and anethole exhibited strong synergism on their bacteriostatic action but only marginal synergism on their bactericidal action... - Effects of mushroom tyrosinase on anisaldehydeTae Joung Ha
Department of Environmental Science, Policy, and Management, University of California, Berkeley, California 94720-3112, USA
J Agric Food Chem 53:7024-8. 2005..Anisaldehyde significantly suppressed the rate of enzymatic oxidation of L-tyrosine... - Kinetics of mushroom tyrosinase inhibition by quercetinQing-Xi Chen
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720-3112, USA
J Agric Food Chem 50:4108-12. 2002..The inhibition of tyrosinase by quercetin is a slow and reversible reaction with residual enzyme activity. The microscopic rate constants were determined for the reaction of quercetin with the enzyme... - Rational design of antimicrobial agents: antifungal activity of alk(en)yl dihydroxybenzoates and dihydroxyphenyl alkanoatesKen-ichi Nihei
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720-3112, USA
Bioorg Med Chem Lett 13:3993-6. 2003..5 and 50 microg/mL. In addition, various 3,4-dihydroxybenzoates, possessing different side chains, namely unsaturated, branched and alicyclic were synthesized and their activity was compared... 
Effect of polygodial on the mitochondrial ATPase of Saccharomyces cerevisiaeC S Lunde
Comparative Biochemistry Group, Policy, and Management, University of California, Berkeley, California 94720, USA
Antimicrob Agents Chemother 44:1943-53. 2000..A major target of polygodial in yeast is mitochondrial ATP synthase. Reduction of the ATP supply leads to a suppression of Pma1 ATPase activity and impairs adaptive responses to other facets of polygodial's cellular inhibition...- Tyrosinase inhibitory activity of the olive oil flavor compoundsI Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley 94720 3112, USA
J Agric Food Chem 47:4574-8. 1999..In addition, the hydrophobic alkyl chain length from the hydrophilic enal group seems to relate to their affinity to the enzyme, and this results in their inhibitory potency... - Plasma membrane injury induced by nonyl gallate in Saccharomyces cerevisiaeK Fujita
Department of Environmental Science, Policy and Management, University of California, Berkeley, California, USA
J Appl Microbiol 92:1035-42. 2002..cerevisiae. When nonyl gallate is applied as a food preservative, the level of its addition to foods may be reduced because of its potent antifungal activity compared with weak acids including sorbic acid and benzoic acid... - Synergistic effects of anacardic acids and methicillin against methicillin resistant Staphylococcus aureusHisae Muroi
Department of Environmental Science, Policy and Management, University of California at Berkeley, CA 94720 3112, USA
Bioorg Med Chem 12:583-7. 2004..Notably, the synergistic effects were noted to increase with increasing the alkyl chain length... - Lipoxygenase inhibitory activity of octyl gallateTae Joung Ha
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720-3112, USA
J Agric Food Chem 52:3177-81. 2004..54 microM. One molecule of octyl gallate scavenged six molecules of 1,1-diphenyl-2-picrylhydrazyl and inhibited autoxidative lipid peroxidation. In addition, octyl gallate was effective in preventing lipid peroxidation... - Molecular design of multifunctional food additives: antioxidative antifungal agentsKen-ichi Nihei
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720-3112, USA
J Agric Food Chem 52:5011-20. 2004..However, the primary fungicidal activity of nonyl 3,4-dihydroxybenzoate likely comes from its ability to act as a surfactant... - Lipoxygenase inhibitory activity of anacardic acidsTae Joung Ha
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
J Agric Food Chem 53:4350-4. 2005..However, the hydrophobic interaction alone is not enough because cardanol (C15:1), which possesses the same side chain as anacardic acid (C15:1), acted neither as a substrate nor as an inhibitor... - Antifungal activity of octyl gallateKen ichi Fujita
Department of Environmental Science, Policy and Management, University of California, Berkeley 94720 3112, USA
Int J Food Microbiol 79:193-201. 2002.... - Multifunctional action of antifungal polygodial against Saccharomyces cerevisiae: involvement of pyrrole formation on cell surface in antifungal actionKen-ichi Fujita
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720-3112, USA
Bioorg Med Chem 13:6742-7. 2005.... - 2-hydroxy-4-isopropylbenzaldehyde, a potent partial tyrosinase inhibitorKen-ichi Nihei
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720-3112, USA
Bioorg Med Chem Lett 14:681-3. 2004..3 microM. The inhibition kinetics analyzed by Dixon plots found that chamaecin is a mixed type inhibitor. This inhibition may come in part from its ability to form a Schiff base with a primary amino group in the enzyme... - Lipoxygenase inhibitory activity of 6-pentadecanylsalicylic acid without prooxidant effectIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3114, USA
Nat Prod Commun 5:85-90. 2010..The inhibition of anacardic acid (C15:0) can be explained by a combination of iron ion-chelation and hydrophobic interaction abilities because of its specific structural feature... - Antibacterial activity of polygodialIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720 3112, USA
Phytother Res 19:1013-7. 2005..The time kill curve study showed that polygodial was bactericidal against B. subtilis and S. choleraesuis. However, there was a difference in its bactericidal action against endospore-forming B. subtilis and food-borne S. choleraesuis... - Inhibition mode of soybean lipoxygenase-1 by quercetinTae Joung Ha
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3114, USA
Chem Biodivers 7:1893-903. 2010..Rutin and kaempferol also exhibited lipoxygenase-1 inhibitory activity, but to a much lesser extent than quercetin... - Evaluation of lipoxygenase inhibitory activity of anacardic acidsIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3114, USA
Z Naturforsch C 63:539-46. 2008..Consequently, the data should be interpreted to mean that changes in the hydrophobic side chain tail portions of the molecules evaluated correlate with the specific activity determined... - Naturally occurring antifungal agents against Zygosaccharomyces bailii and their synergismKen-ichi Fujita
Department of Environmental Science, Policy and Management, University of California, Berkeley, 94720-3112, USA
J Agric Food Chem 53:5187-91. 2005..The fungicidal activity of sorbic acid was enhanced 512-fold in combination with 1/2 MFC of polygodial. Conversely, the fungicidal activity of polygodial was enhanced 128-fold in combination with 1/2 MFC of sorbic acid... - Multifunctional cytotoxic agents from Anacardium occidentaleIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3114, USA
Phytother Res 25:38-45. 2011..Both anacardic acids and cardols exhibited moderate cytotoxicity... - Tyrosinase inhibition kinetics of anisic acidIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
Z Naturforsch C 58:713-8. 2003..603 mM. Anisic acid also inhibited the hydroxylation of L-tyrosine catalyzed by tyrosinase. The lag phase caused by the monophenolase activity was lengthened and the steady-state activity of the enzyme was decreased by anisic acid... - Tyrosinase inhibitors from galls of Rhus javanica leaves and their effects on insectsIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
Z Naturforsch C 58:719-25. 2003..18.1) with an IC50 of 22 microM. The aphid would detoxify the ingested toxic tannic acid to relatively nontoxic gallic acid, whereas the non-adapted pink bollworm Pectinophora gossypiella larvae are sensitive to the ingested tannic acid... - Modes of antifungal action of alkanols against Saccharomyces cerevisiaeIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720 3112, USA
Bioorg Med Chem 11:1117-22. 2003..Hence, the antifungal activity of alkanols is mediated by biophysical process, and the maximum activity can be obtained when balance between hydrophilic and hydrophobic portions becomes the most appropriate... - Non-antibiotic antibacterial activity of dodecyl gallateIsao Kubo
Department of Environmental Science, Policy and Management, University of California, CA 94720 3112, Berkeley, USA
Bioorg Med Chem 11:573-80. 2003..As far as alkyl gallates are concerned, their antimicrobial spectra and potency depend in part on the hydrophobic portion of the molecule... - QSAR and kinetics of the inhibition of benzaldehyde derivatives against Sacrophaga neobelliaria phenoloxidaseWei Li
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720-3112, USA
Bioorg Med Chem 12:701-13. 2004.... - Antioxidant activity of dodecyl gallateIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
J Agric Food Chem 50:3533-9. 2002..Dodecyl gallate protected mitochondrial functions and human red blood cells against oxidative stresses, but gallic acid showed little effect. The hydrophobic dodecyl group is largely associated with the preventive antioxidative activity... - Molecular design of antifungal agentsIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
J Agric Food Chem 50:3992-8. 2002..As far as alkyl gallates are concerned, their antimicrobial spectra and potency depend largely on the hydrophobic portion of the molecules... - Effects of quercetin on mushroom tyrosinase and B16-F10 melanoma cellsIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720 3114, USA
Molecules 12:1045-56. 2007..The concentration leading to 50% viable cells lost was established as 20 microM and almost complete lethality was observed at 80 microM... - Anti-Salmonella activity of alkyl gallatesIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
J Agric Food Chem 50:6692-6. 2002.... - Antibacterial activity of ent-kaurene diterpenoids from Rabdosia rosthorniiIsao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720 3112, USA
Phytother Res 18:180-3. 2004..They exhibited antibacterial activity specifically against Gram-positive bacteria, among which Propionibacterium acnes was noted to be the most susceptible... - Antibacterial action of anacardic acids against methicillin resistant Staphylococcus aureus (MRSA)Isao Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
J Agric Food Chem 51:7624-8. 2003..The compounds possessing the similar log P values exhibit similar activity... - Anti-Helicobacter pylori agents from the cashew appleJ Kubo
Department of Environmental Science, Policy and Management, University of California, Berkeley 94720 3112, USA
J Agric Food Chem 47:533-7. 1999..The same antibacterial compounds have also been found to inhibit urease (EC 3.5.1.5)... - Anisaldehyde, a melanogenesis potentiatorTeruhiko Nitoda
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720, USA
Z Naturforsch C 62:143-9. 2007..The melanin content per cell at 1 mM was increased 5-fold compared to control and morphological observations showed the deposition of melanin pigments. Anisaldehyde was also examined against cultured human A375 melanoma cells... - Structural criteria for depigmenting mechanism of arbutinIkuyo Hori
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA, USA
Phytother Res 18:475-9. 2004..The depigmenting mechanism of arbutin previously reported is supportable if a cofactor is not available in the melanocytes. The combination with L-ascorbic acid is a useful application, particularly when oxygen is limited... - Effects of cuminaldehyde on melanoma cellsTeruhiko Nitoda
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720, USA
Phytother Res 22:809-13. 2008..25 mm without affecting cell growth. Approximately 30% suppression in melanin production resulted when the cells were cultured with 0.25 mm of cuminaldehyde. This activity was not noticeable with cultured human A375 melanoma cells... - Antifungal activity of alkanols against Zygosaccharomyces bailii and their effects on fungal plasma membraneKen ichi Fujita
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3114, USA
Phytother Res 22:1349-55. 2008..The antifungal activity of decanol against Z. bailii was slightly enhanced in combination with anethole... - Volatile aldehydes are promising broad-spectrum postharvest insecticidesD G Hammond
Agricultural and Environmental Chemistry Group and Department of Environmental Science, Policy and Management, 201 Wellman Hall, University of California at Berkeley, Berkeley, California 94720 3112, USA
J Agric Food Chem 48:4410-7. 2000..Preliminary assays indicate that similar doses are also effective against mealybugs, thrips, and whitefly... - Slow-binding inhibition of soybean lipoxygenase-1 by dodecyl gallateTae Joung Ha
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3114, USA
J Agric Food Chem 55:446-51. 2007..Both the initial velocity and steady-state rate in the progress curve decreased with increasing dodecyl gallate. The kinetic parameters that described the inhibition by dodecyl gallate were evaluated by nonlinear regression fits... - Insect antifeedants from tropical plants: structures of dumnin and dumseninKen-ichi Nihei
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720-3112, USA
J Agric Food Chem 52:3325-8. 2004..0 microg/mL) against the larvae of pink bollworm, Pectinophora gossypiella, and/or fall armyworm, Spodoptera frugiperda, providing results comparable to dumsin and zumsin, previously isolated from the same plant... - Insect antifeedants from tropical plants II: structure of zumsinKen-ichi Nihei
Department of Environmental Science, Policy and Management, University of California, Berkeley 94720-3112, USA
J Agric Food Chem 50:5048-52. 2002..The structure consists of an A'-B trans-fused ring while dumsin (2), a constituent of the same source, maintains an A'-B cis-fused ring, and suggests two unique biosynthetic processes after A ring oxidative expansion... - Hydroquinone, a control agent of agglutination and adherence of Streptococcus mutans induced by sucroseMasaki Himejima
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720-3112, USA
Bioorg Med Chem 12:921-5. 2004..The agglutination altering activity of hydroquinone seems to be specific for strains of S. mutans. As a result, hydroquinone inhibits sucrose-induced adherence of S. mutans... - Alkanols inhibit respiration of intact mitochondria and display cutoff similar to that measured in vivoD G Hammond
Department of Environmental Science, Policy, and Management, University of California, Berkeley, USA
J Pharmacol Exp Ther 293:822-8. 2000.... - Insect antifeedants from Croton jatrophoides: structures of zumketol, zumsenin, and zumsenolKen-ichi Nihei
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720-31122, USA
J Nat Prod 68:244-7. 2005..The alpha-ketol 1 may be biosynthesized via the intramolecular acyloin condensation of a dicarboxylate intermediate... - Arudonine, an allelopathic steroidal glycoalkaloid from the root bark of Solanum arundo MatteiKatsuya Fukuhara
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720-3112, USA
Phytochemistry 65:1283-6. 2004..This steroidal glycoalkaloid inhibited the growth of lettuce seedlings (Lactuca sativa)... - (+)-2,3-dehydro-10-oxo-alpha-isosparteine in Uresiphita reversalis larvae fed on Cytisus monspessulanus leavesKen ichi Nihei
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720 3112, USA
Phytochemistry 61:987-90. 2002..In addition, the quinolizidine alkaloid, (+)-2,3-dehydro-10-oxo-alpha-isosparteine was characterized in both the insect and host plant... - Pachyelasides A-D, novel molluscicidal triterpene saponins from Pachyelasma tessmanniiKen-ichi Nihei
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720-3112, USA
J Agric Food Chem 53:608-13. 2005..The structures were determined on the basis of extensive nuclear magnetic resonance spectroscopic and matrix-assisted laser desorption/ionization time-of-flight mass spectrometric studies... - Anacardic acids and ferric ion chelationKazuo Tsujimoto
School of Material Sciences, Japan Advanced Institute of Science and Technology, Nomi, Ishikawa 923 1292, Japan
Z Naturforsch C 62:710-6. 2007..Formation of the anacardic acids-ferric ion complex was detected in the ratio of 2:1 as the base peak in the negative ion electrospray ionization mass spectrometry. Hence, anacardic acids inhibit both Eox and Ered forms... - Design and evaluation of anacardic acid derivatives as anticavity agentsIvan R Green
Department of Chemistry, University of the Western Cape, P Bag X17, Bellville, 7530, South Africa
Eur J Med Chem 43:1315-20. 2008..Among them, 6-(4',8'-dimethylnonyl)salicylic acid was found to exhibit the most potent antibacterial activity against this cariogenic bacterium with the minimum inhibition concentration (MIC) of 0.78 microg/ml... - Molecular design of anti-MRSA agents based on the anacardic acid scaffoldIvan R Green
Department of Chemistry, University of the Western Cape, Bellville 7530, South Africa
Bioorg Med Chem 15:6236-41. 2007..This activity was superior to that of the most potent antibacterial anacardic acid isolated from the cashew Anacardium occidentale (Anacardiaceae), apple and nut, that is, the 6-[8'(Z),11'(Z),14'-pentadecatrienyl]salicylic acid... - Xanthine oxidase inhibitory activity of alkyl gallatesNoriyoshi Masuoka
Department of Life Science, Okayama University of Science, Ridai cho, Okayama, Japan
Mol Nutr Food Res 50:725-31. 2006..The suppression is not due to scavenging activity of these gallates but due to reduction of xanthine oxidase by these gallates. The reduced enzyme catalyzes the reaction to generate hydrogen peroxide and uric acid... - Antioxidants from Rabdosia japonicaNoriyoshi Masuoka
Department of Biochemistry, Okayama University Graduate School of Medicine and Dentistry, Okayama 700-8558, Japan
Phytother Res 20:206-13. 2006..On the other hand, isoquercitrin, rutin and rosmarinic acid were effective in scavenging superoxide radicals generated by the xanthine-xanthine oxidase system without inhibiting the enzyme... - Synergism of polygodial and trans-cinnamic acid on inhibition of root elongation in lettuce seedling growth bioassaysKen ichi Fujita
Graduate School of Science, Osaka City University, 3 3 138 Sugimoto, Sumiyoshi ku, Osaka 558 8585, Japan
J Chem Ecol 29:2253-62. 2003..These results suggest that polygodial functions synergistically with trans-cinnamic acid in the inhibition of root elongation via restriction of proton transport from the cytoplasm of germinated cells... - Inactivation kinetics of mushroom tyrosinase by cetylpyridinium chlorideQing Xi Chen
Key Laboratory of Ministry of Education for Cell Biology and Tumor Cell Engineering, Department of Biology, Xiamen University, Xiamen 361005, People s Republic of China
J Protein Chem 22:481-7. 2003..The micro rate constants of inactivation and the association constant were determined... - Characterization of xanthine oxidase inhibition by anacardic acidsNoriyoshi Masuoka
Department of Biochemistry, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikatacho, Okayama 700 8558, Japan
Biochim Biophys Acta 1688:245-9. 2004..Salicylic acid moiety and alkenyl side chain in anacardic acid are associated with the cooperative inhibition and hydrophobic binding, respectively... - Musidunin and musiduol, insect antifeedants from Croton jatrophoidesKen-ichi Nihei
Department of Applied Biochemistry, Faculty of Agriculture, Utsunomiya University, Utsunomiya, Tochigi 321-0943, Japan
J Nat Prod 69:975-7. 2006..Interestingly, A,B-seco limonoid 1 contains a unique acetal annulation of A, A', and B' rings. Both limonoids exhibited antifeedant activities against two pests, Pectinophora gossypiella and Spodoptera frugiperda...