Research Topics
Species | Donna Kritz-SilversteinSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Isoflavones and cognitive function in older women: the SOy and Postmenopausal Health In Aging (SOPHIA) StudyDonna Kritz-Silverstein
University of California, San Diego, School of Medicine, Department of Family and Preventive Medicine, Division of Epidemiology, La Jolla 92093, USA
Menopause 10:196-202. 2003..This study examines the effects of a dietary supplement of isoflavones on cognitive function in postmenopausal women...- Hysterectomy status, estrogen use and quality of life in older women: the Rancho Bernardo studyDonna Kritz-Silverstein
Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, CA, USA
Qual Life Res 13:55-62. 2004..To examine the long-term effects of hysterectomy and use of estrogen replacement therapy on health related quality of life and symptom subscales in community dwelling postmenopausal women... 
Effects of dehydroepiandrosterone supplementation on cognitive function and quality of life: the DHEA and Well-Ness (DAWN) TrialDonna Kritz-Silverstein
Department of Family and Preventive Medicine, School of Medicine, University of California at San Diego, La Jolla, California 92093 0631, USA
J Am Geriatr Soc 56:1292-8. 2008..To examine the effects of dehydroepiandrosterone (DHEA) supplementation on cognitive function and quality of life in healthy older adults...- Breast cancer and bone mass in older women: is bone density prescreening for mammography useful?D Kritz-Silverstein
Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, 0631 C, La Jolla, 92093 0631, USA
Osteoporos Int 17:1196-201. 2006..This case-control study compares BMD at multiple sites in women with and without breast cancer to determine if BMD prescreening is useful in selecting women for continued screening mammograms... - The association of thyroid stimulating hormone levels with cognitive function and depressed mood: the Rancho Bernardo studyD Kritz-Silverstein
Department of Family and Preventive Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0607, USA
J Nutr Health Aging 13:317-21. 2009..To evaluate the association of thyroid stimulating hormone levels with cognitive function and depressed mood in a community-based sample... - Hysterectomy and oophorectomy are unrelated to bone loss in older womenDonna Kritz-Silverstein
Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, 0631 C, La Jolla, CA 92093 0607, USA
Maturitas 47:61-9. 2004..The relation of hysterectomy and oophorectomy to change in bone mineral density (BMD) was examined in older women using and not using estrogen replacement therapy (ERT)... - Elevated natriuretic peptide levels and cognitive function in community-dwelling older adultsLori B Daniels
Division of Cardiology, Department of Medicine, University of California at San Diego, USA
Am J Med 124:670.e1-8. 2011..We assessed the association between N-terminal pro B-type natriuretic peptide (NT-proBNP) levels and cognitive function in community-dwelling ambulatory older adults in the Rancho Bernardo Study... - The Dehydroepiandrosterone And WellNess (DAWN) study: research design and methodsDenise von Muhlen
University of California, San Diego, United States
Contemp Clin Trials 28:153-68. 2007..Potential mechanisms of DHEA action, including the biotransformation of DHEA to active steroids and steroid metabolites, enhancement of IGF-I bioavailability, and inhibition of IL-6 production can also be evaluated... - New onset and persistent symptoms of post-traumatic stress disorder self reported after deployment and combat exposures: prospective population based US military cohort studyTyler C Smith
Department of Defense Center for Deployment Health Research at the Naval Health Research Center, San Diego, CA 92106, USA
BMJ 336:366-71. 2008..To describe new onset and persistence of self reported post-traumatic stress disorder symptoms in a large population based military cohort, many of whom were deployed in support of the wars in Iraq and Afghanistan... - Metabolic syndrome and 16-year cognitive decline in community-dwelling older adultsLinda K McEvoy
Department of Radiology, University of California, San Diego, La Jolla, CA, USA
Ann Epidemiol 22:310-7. 2012..To determine whether metabolic syndrome is associated with accelerated cognitive decline in community-dwelling older adults... - Sex differences in the association of Framingham Cardiac Risk Score with cognitive decline in community-dwelling elders without clinical heart diseaseGail A Laughlin
Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA
Psychosom Med 73:683-9. 2011.... - Hormone use and lung cancer incidence: the Rancho Bernardo cohort studyJoshua R Smith
Department of Family and Preventive Medicine, School of Medicine, University of California San Diego, La Jolla, CA, USA
Menopause 16:1044-8. 2009..This study examines the association of hormone use and lung cancer among women... - Vitamin D, parathyroid hormone levels, and the prevalence of metabolic syndrome in community-dwelling older adultsJared P Reis
Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California 92093 0607, USA
Diabetes Care 30:1549-55. 2007..We examined the association of 25(OH)D and PTH with the prevalence of metabolic syndrome in a community-based cohort of older adults... - Modifiable predictors of bone loss in older men: a prospective studyLudmila N Bakhireva
University of California, San Diego, Department of Family and Preventive Medicine, Division of Epidemiology, La Jolla, California 92093-0607, USA
Am J Prev Med 26:436-42. 2004..Potentially modifiable characteristics such as low body mass, weight loss, smoking, and physical inactivity were important predictors of bone loss and should be considered for the prevention of osteoporosis in men... - The prospective association of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: the Rancho Bernardo StudyGail A Laughlin
Department of Family and Preventive Medicine, University of California San Diego School of Medicine, La Jolla, California 92093 0607
J Clin Endocrinol Metab 89:114-20. 2004..We conclude that low baseline levels of IGF-I and IGFBP-1 increase the risk of fatal IHD among elderly men and women independent of prevalent IHD and CVD risk factors... - Walking decreased risk of cardiovascular disease mortality in older adults with diabetesTyler C Smith
Division of Epidemiology, Department of Family and Preventive Medicine, University of California San Diego, 9500 Gilman Drive 0607, La Jolla, CA 92093 0607, USA
J Clin Epidemiol 60:309-17. 2007..This study examines the association of walking with mortality in persons with type 2 diabetes compared to those with normal glucose tolerance... - Pet ownership and blood pressure in old ageJoel David Wright
University of California, San Diego, CA 92093 0631, USA
Epidemiology 18:613-8. 2007..This study examines the relation of pet ownership with systolic and diastolic blood pressure, pulse pressure, mean arterial pressure, and hypertension in a large sample of older men and women... - The association of angina pectoris with heart disease mortality among men and women by diabetes status: the Rancho Bernardo StudyKimbach T Carpiuc
Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California 92093 0607, USA
J Womens Health (Larchmt) 19:1433-9. 2010..To study the sex-specific association of angina pectoris with mortality in community-dwelling older adults with and without diabetes... - Is radiographic vertebral fracture a risk factor for mortality?Daniel W Trone
Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
Am J Epidemiol 166:1191-7. 2007..04) but not cardiovascular disease or cancer. A single radiographic vertebral fracture is not a risk for mortality in older women; larger, longer studies of men and those with two or more radiographic vertebral fractures are needed... - The association of reproductive history with all-cause and cardiovascular mortality in older women: the Rancho Bernardo StudyMarni B Jacobs
Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, California 92093 0607, USA
Fertil Steril 97:118-24. 2012..To examine associations of gravidity and parity with all-cause, cardiovascular disease (CVD), and coronary heart disease (CHD) mortality in postmenopausal women... 
Prior assault and posttraumatic stress disorder after combat deploymentTyler C Smith
Department of Defense Center for Deployment Health Research, Naval Health Research Center, San Diego, CA 92186 5122, USA
Epidemiology 19:505-12. 2008..The objective of this study was to prospectively examine the relation between prior assault and new-onset PTSD symptoms in a large US military cohort deployed in the wars in Iraq and Afghanistan...- Endogenous oestrogens predict 4-year decline in verbal fluency in postmenopausal women: the Rancho Bernardo StudyGail A Laughlin
Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, CA 92093, USA
Clin Endocrinol (Oxf) 72:99-106. 2010..This study examines the association between endogenous oestrogen levels and subsequent 4-year decline in cognitive function test performance in community-dwelling older women... - Differences in association of bone mineral density with coronary artery calcification in men and women: the Rancho Bernardo StudyLudmila N Bakhireva
Department of Family and Preventive Medicine, Division of Epidemiology, University of California, San Diego, La Jolla, 92093-0607, USA
Menopause 12:691-8. 2005..1). CONCLUSION: Lack of association between BMD and CACS in men and women not using HT and the inverse association in women on HT suggest that the association between coronary and bone calcium might be mediated by estrogen... - Insulin-like growth factor-I and cancer mortality in older menJacqueline M Major
Department of Family and Preventive Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093 0631C, USA
J Clin Endocrinol Metab 95:1054-9. 2010..These results suggest caution in the use of IGF-I-enhancing therapies to slow the adverse effects of aging... - Estrogen therapy and bone mineral density in African-American and Caucasian womenSusan L Eskridge
San Diego Joint Doctoral Program in Public Health Epidemiology, San Diego State University University of California, San Diego, California, USA
Am J Epidemiol 171:808-16. 2010..13-0.37). Results suggest that higher levels of bone mineral density in African-American women were not due to estrogen use... - Hysterectomy status and life satisfaction in older womenDonna Kritz-Silverstein
Department of Family and Preventive Medicine, Division of Epidemiology, University of California, San Diego, La Jolla, USA
J Womens Health Gend Based Med 11:181-90. 2002..Relief from symptoms necessitating hysterectomy may be responsible for this increase. This difference may be specific to hysterectomy because there were no differences in general life satisfaction as assessed with standardized measures... - Sensitivity and specificity of death certificates for diabetes: as good as it gets?W Susan Cheng
Joint Doctoral Program, University of California, San Diego, La Jolla, CA 92093 0607, USA
Diabetes Care 31:279-84. 2008..In this study we examined death certificate sensitivity and specificity for diabetes, as well as the factors related to better reporting, in a community-based sample... - Regular alcohol consumption is associated with increasing quality of life and mood in older men and women: the Rancho Bernardo StudyAmanda Michele Chan
Thurgood Marshall College, University of California, San Diego, La Jolla, CA, USA
Maturitas 62:294-300. 2009..This study examines the sex-specific association between alcohol intake and health-related quality of life in middle class community-dwelling older adults... - Bone mineral density in postmenopausal Caucasian, Filipina, and Hispanic womenDeborah J Morton
University of California, San Diego, La Jolla, CA 92093, USA
Int J Epidemiol 32:150-6. 2003.... - Premature graying, balding, and low bone mineral density in older women and men: the Rancho Bernardo studyDeborah J Morton
Department of Family and Preventive Medicine, Division of Epidemiology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0622, USA
J Aging Health 19:275-85. 2007..The authors report the association of balding or graying with BMD in older adults... - Usual dietary isoflavone intake and body composition in postmenopausal womenDeborah Goodman-Gruen
University of California, San Diego, Department of Family and Preventive Medicine, La Jolla, CA, USA
Menopause 10:427-32. 2003..The purpose of this study was to investigate the cross-sectional association between isoflavone consumption from a typical Western diet and measures of total body fat, body fat distribution and lean body mass... - Hysterectomy, oophorectomy, and cognitive function in older womenDonna Kritz-Silverstein
Department of Family and Preventive Medicine, University of California, San Diego, California 92093, USA
J Am Geriatr Soc 50:55-61. 2002.... - Apolipoprotein E genotype and response of lipid levels to postmenopausal estrogen useDenise von Muhlen
Department of Family and Preventive Medicine, Division of Epidemiology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0607, USA
Atherosclerosis 161:209-14. 2002..015). The unfavorable effect of ApoE 4 genotype on lipoproteins is not altered by HRT, but ApoE 2 genotype modulates the HDL-ERT association in older women... - Coffee consumption and cognitive function among older adultsMarilyn Johnson-Kozlow
Department of Family and Preventive Medicine, University of California, San Diego, La Jolla 92093, USA
Am J Epidemiol 156:842-50. 2002..Lifetime and current exposure to caffeine may be associated with better cognitive performance among women, especially among those aged 80 or more years... - Does coffee consumption reduce the risk of type 2 diabetes in individuals with impaired glucose?Besa Smith
Department of Family and Preventive Medicine, University of California San Diego, 9500 Gilman Dr 0607, La Jolla, CA 92093 0607, USA
Diabetes Care 29:2385-90. 2006.... - Treated hypothyroidism, cognitive function, and depressed mood in old age: the Rancho Bernardo StudyCaroline K Kramer
Division of Epidemiology, Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, California 92093 0607, USA
Eur J Endocrinol 161:917-21. 2009..Overt hypothyroidism is associated with cognitive impairment, which can be reversed if treated early and appropriately. We compared cognitive function (CF) of euthyroid older adults with those who had long-term treated hypothyroidism... - PTSD prevalence, associated exposures, and functional health outcomes in a large, population-based military cohortTyler C Smith
Department of Defense Center for Deployment Health Research, Naval Health Research Center, P O Box 85122, San Diego, CA 92186 5122, USA
Public Health Rep 124:90-102. 2009..The purpose of this study was to investigate the prevalence of PTSD symptoms and diagnosis, self-reported exposures, and functional health in a large cross-section of the U.S. military... - A longitudinal study of stress in first-year dental studentsSarah T Silverstein
Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, 9500 Gilman Drive, 0631 C, La Jolla, CA 92093, USA
J Dent Educ 74:836-48. 2010..Changes in sources of stress may reflect the different contributions of anticipatory and situational stress over time. First-year dental students may benefit from stress reduction programs... - Birth weight and cognitive performance in older women: the Rancho Bernardo studyKirsten Erickson
Department of Family and Preventive Medicine, University of California, San Diego, San Diego, CA, USA
Arch Womens Ment Health 13:141-6. 2010..Although this association could be spurious, it deserves further evaluation... - High dietary and plasma levels of the omega-3 fatty acid docosahexaenoic acid are associated with decreased dementia risk: the Rancho Bernardo studyL B Lopez
Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California 92093, USA
J Nutr Health Aging 15:25-31. 2011..This study examined the association of plasma DHA, dietary DHA, and fish intake with dementia and Alzheimer's Disease (AD) in older adults... - Sarcopenia in elderly men and women: the Rancho Bernardo studyEdward M Castillo
Joint Doctoral Program, Public Health, San Diego State University/University of California, San Diego, La Jolla, California, USA
Am J Prev Med 25:226-31. 2003..CONCLUSIONS: Sarcopenia increases with age. This study also identified lack of physical activity and current smoking as reversible risk factors for sarcopenia... - Five-year stability in associations of health-related quality of life measures in community-dwelling older adults: the Rancho Bernardo StudyClaudia Der-Martirosian
Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0607, La Jolla, CA 92093 0631, USA
Qual Life Res 19:1333-41. 2010..This study examines the five-year stability of the association of SF-12 and SF-6D scores with scores on the longer SF-36 and its domains in community-dwelling older men and women... - Usual dietary isoflavone intake, bone mineral density, and bone metabolism in postmenopausal womenDonna Kritz-Silverstein
University of California, San Diego, School of Medicine, Department of Family and Preventive Medicine, Division of Epidemiology, La Jolla, California 92093-0631, USA
J Womens Health Gend Based Med 11:69-78. 2002..These results suggest that usual, unsupplemented dietary isoflavone consumption may be protective against bone loss in postmenopausal women through a reduction in bone resorption... - A prospective study of albuminuria and cognitive function in older adults: the Rancho Bernardo studySimerjot K Jassal
VA San Diego Healthcare System, 3350 La Jolla Village Drive, Division of GIM G, MC 111N, San Diego, CA 92161, USA
Am J Epidemiol 171:277-86. 2010..Albuminuria may be an easily measured marker predicting future cognitive function decline. Results imply a common underlying mechanism affecting the renal and cerebral microvasculature...
Research Grants
- CVD RISK & HEALTH IN POSTMENOPAUSAL PHYTOESTROGEN USERSDonna Kritz Silverstein; Fiscal Year: 2001....
- CVD Mechanisms Associated with Phytoestrogens UseDonna Kritz Silverstein; Fiscal Year: 2003..Given that women can expect to live one-third of their lives after menopause, it is important to know whether and how phytoestrogens may modify cardiovascular disease mechanisms. ..