Vaishnav Krishnan

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi Calcium-sensitive adenylyl cyclases in depression and anxiety: behavioral and biochemical consequences of isoform targeting
    Vaishnav Krishnan
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Biol Psychiatry 64:336-43. 2008
  2. ncbi Linking molecules to mood: new insight into the biology of depression
    Vaishnav Krishnan
    Department of Psychiatry, University of Texas Southwestern Medical Center, USA
    Am J Psychiatry 167:1305-20. 2010
  3. ncbi Animal models of depression: molecular perspectives
    Vaishnav Krishnan
    Departments of Internal Medicine, Psychiatry and Neuroscience, The University of Texas Southwestern Medical Center, Dallas, TX, USA
    Curr Top Behav Neurosci 7:121-47. 2011
  4. ncbi AKT signaling within the ventral tegmental area regulates cellular and behavioral responses to stressful stimuli
    Vaishnav Krishnan
    Department of Psychiatry and Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Biol Psychiatry 64:691-700. 2008
  5. ncbi Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions
    Vaishnav Krishnan
    Department of Psychiatry, The University of Texas Southwestern Medical Center UTSWMC, 5323 Harry Hines Boulevard, Dallas, TX 75390 9070, USA
    Cell 131:391-404. 2007
  6. ncbi Orexin signaling mediates the antidepressant-like effect of calorie restriction
    Michael Lutter
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9070, USA
    J Neurosci 28:3071-5. 2008
  7. ncbi Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli
    William Renthal
    Department of Psychiatry and Basic Neuroscience, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9070, USA
    Neuron 56:517-29. 2007
  8. ncbi Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses
    Olivier Berton
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Neuron 55:289-300. 2007
  9. ncbi CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits
    Deanna L Wallace
    Department of Psychiatry and Neuroscience, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9070, USA
    Nat Neurosci 12:200-9. 2009
  10. ncbi Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance
    Diane C Lagace
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Proc Natl Acad Sci U S A 107:4436-41. 2010

Collaborators

Detail Information

Publications15

  1. ncbi Calcium-sensitive adenylyl cyclases in depression and anxiety: behavioral and biochemical consequences of isoform targeting
    Vaishnav Krishnan
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Biol Psychiatry 64:336-43. 2008
    ..This study examines the contribution of these AC isoforms to emotional behavior...
  2. ncbi Linking molecules to mood: new insight into the biology of depression
    Vaishnav Krishnan
    Department of Psychiatry, University of Texas Southwestern Medical Center, USA
    Am J Psychiatry 167:1305-20. 2010
    ..The authors provide recommendations for future research, with a focus on translating today's discoveries into improved diagnostic tests and treatments...
  3. ncbi Animal models of depression: molecular perspectives
    Vaishnav Krishnan
    Departments of Internal Medicine, Psychiatry and Neuroscience, The University of Texas Southwestern Medical Center, Dallas, TX, USA
    Curr Top Behav Neurosci 7:121-47. 2011
    ..These paradigms are critically evaluated in relation to their ease, validity and replicability, the molecular insights that they have provided, and their capacity to offer the next generation of therapeutics for depression...
  4. ncbi AKT signaling within the ventral tegmental area regulates cellular and behavioral responses to stressful stimuli
    Vaishnav Krishnan
    Department of Psychiatry and Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Biol Psychiatry 64:691-700. 2008
    ..Recent evidence suggests that dopaminergic neurons of the ventral tegmental area (VTA) play a key role in the manifestation of stress vulnerability...
  5. ncbi Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions
    Vaishnav Krishnan
    Department of Psychiatry, The University of Texas Southwestern Medical Center UTSWMC, 5323 Harry Hines Boulevard, Dallas, TX 75390 9070, USA
    Cell 131:391-404. 2007
    ....
  6. ncbi Orexin signaling mediates the antidepressant-like effect of calorie restriction
    Michael Lutter
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9070, USA
    J Neurosci 28:3071-5. 2008
    ..Together, these data indicate that orexin plays an essential role in mediating reduced depression-like symptoms induced by calorie restriction...
  7. ncbi Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli
    William Renthal
    Department of Psychiatry and Basic Neuroscience, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9070, USA
    Neuron 56:517-29. 2007
    ....
  8. ncbi Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses
    Olivier Berton
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Neuron 55:289-300. 2007
    ..These results indicate that IS-induced accumulation of DeltaFosB in the vlPAG desensitizes substance P neurons enriched in this area and opposes behavioral despair by promoting active defense responses...
  9. ncbi CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits
    Deanna L Wallace
    Department of Psychiatry and Neuroscience, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9070, USA
    Nat Neurosci 12:200-9. 2009
    ....
  10. ncbi Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance
    Diane C Lagace
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Proc Natl Acad Sci U S A 107:4436-41. 2010
    ....
  11. ncbi A beta3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress
    Jen Chieh Chuang
    Department of Internal Medicine Division of Hypothalamic Research, The University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Biol Psychiatry 67:1075-82. 2010
    ..Likewise, these stress-related disturbances are associated with a higher rate of obesity; yet, the neurobiological mechanisms linking obesity and stress remain incompletely understood...
  12. ncbi The use of animal models in psychiatric research and treatment
    Vaishnav Krishnan
    Department of Psychiatry, UT Southwestern Medical Center, 5323 Harry Hines Blvd, NE5.110, Dallas, TX 75390-9070, USA
    Am J Psychiatry 165:1109. 2008
  13. ncbi Mania-like behavior induced by disruption of CLOCK
    Kole Roybal
    Department of Psychiatry and Center for Basic Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Proc Natl Acad Sci U S A 104:6406-11. 2007
    ..These findings establish the Clock mutant mice as a previously unrecognized model of human mania and reveal an important role for CLOCK in the dopaminergic system in regulating behavior and mood...
  14. ncbi The molecular neurobiology of depression
    Vaishnav Krishnan
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Nature 455:894-902. 2008
    ..They also show that understanding the mechanisms of resilience to stress offers a crucial new dimension for the development of fundamentally novel antidepressant treatments...
  15. ncbi Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress
    Olivier Berton
    Department of Psychiatry and Center for Basic Neuroscience, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9070, USA
    Science 311:864-8. 2006
    ..These results establish an essential role for BDNF in mediating long-term neural and behavioral plasticity in response to aversive social experiences...