JOHN KRIEGER

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Prostatitis: what is the role of infection
    John N Krieger
    Department of Urology, School of Medicine, University of Washington, 112 UR, VA Puget Sound Health Care System, 1660 South Columbian Way, Seattle, WA 98108 1597, USA
    Int J Antimicrob Agents 19:475-9. 2002
  2. ncbi request reprint Epidemiology of prostatitis: new evidence for a world-wide problem
    John N Krieger
    Department of Urology, University of Washington School of Medicine, VAPSHCS 112 GU, 1600 South Columbian Way, Seattle, WA 98108, USA
    World J Urol 21:70-4. 2003
  3. ncbi request reprint Seminal fluid analysis in chronic prostatitis/chronic pelvic pain syndrome
    J N Krieger
    Department of Urology, University of Washington, Seattle, WA 98108, USA
    Andrologia 35:266-70. 2003
  4. ncbi request reprint Classification, epidemiology and implications of chronic prostatitis in North America, Europe and Asia
    J N Krieger
    Department of Urology, University of Washington, School of Medicine, Seattle, WA, USA
    Minerva Urol Nefrol 56:99-107. 2004
  5. ncbi request reprint Adult male circumcision: results of a standardized procedure in Kisumu District, Kenya
    John N Krieger
    Department of Urology, University of Washington, Box 356510, Seattle, WA 98195, USA
    BJU Int 96:1109-13. 2005
  6. ncbi request reprint Inconsistent localization of gram-positive bacteria to prostate-specific specimens from patients with chronic prostatitis
    John N Krieger
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Urology 66:721-5. 2005
  7. ncbi request reprint Adult male circumcision outcomes: experience in a developing country setting
    John N Krieger
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Urol Int 78:235-40. 2007
  8. doi request reprint Male circumcision and HIV infection risk
    John N Krieger
    Department of Urology, School of Medicine, University of Washington, Seattle, WA 98195, USA
    World J Urol 30:3-13. 2012
  9. pmc Epidemiology of prostatitis
    John N Krieger
    Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
    Int J Antimicrob Agents 31:S85-90. 2008
  10. pmc Adult male circumcision: effects on sexual function and sexual satisfaction in Kisumu, Kenya
    John N Krieger
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    J Sex Med 5:2610-22. 2008

Research Grants

Collaborators

Detail Information

Publications51

  1. ncbi request reprint Prostatitis: what is the role of infection
    John N Krieger
    Department of Urology, School of Medicine, University of Washington, 112 UR, VA Puget Sound Health Care System, 1660 South Columbian Way, Seattle, WA 98108 1597, USA
    Int J Antimicrob Agents 19:475-9. 2002
    ..Understanding the precise role of infection in this syndrome may well lead to better methods to elucidate the microbiology of the prostate in health and disease...
  2. ncbi request reprint Epidemiology of prostatitis: new evidence for a world-wide problem
    John N Krieger
    Department of Urology, University of Washington School of Medicine, VAPSHCS 112 GU, 1600 South Columbian Way, Seattle, WA 98108, USA
    World J Urol 21:70-4. 2003
    ..These data suggest that chronic prostatitis is an important international health care problem that merits increased priority from clinicians and researchers...
  3. ncbi request reprint Seminal fluid analysis in chronic prostatitis/chronic pelvic pain syndrome
    J N Krieger
    Department of Urology, University of Washington, Seattle, WA 98108, USA
    Andrologia 35:266-70. 2003
    ..The aim of this study is to examine our experience with seminal fluid analysis in this patient population, and to outline the potential utility of this examination in patient evaluation...
  4. ncbi request reprint Classification, epidemiology and implications of chronic prostatitis in North America, Europe and Asia
    J N Krieger
    Department of Urology, University of Washington, School of Medicine, Seattle, WA, USA
    Minerva Urol Nefrol 56:99-107. 2004
    ..These findings support the conclusions that chronic prostatitis is an important international health care problem that merits increased priority from clinicians as well as increased clinical and basic science research...
  5. ncbi request reprint Adult male circumcision: results of a standardized procedure in Kisumu District, Kenya
    John N Krieger
    Department of Urology, University of Washington, Box 356510, Seattle, WA 98195, USA
    BJU Int 96:1109-13. 2005
    ....
  6. ncbi request reprint Inconsistent localization of gram-positive bacteria to prostate-specific specimens from patients with chronic prostatitis
    John N Krieger
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Urology 66:721-5. 2005
    ..To determine the rate of gram-positive localizations and whether repetitive cultures demonstrate consistent localization of gram-positive bacteria in patients with chronic prostatitis symptoms...
  7. ncbi request reprint Adult male circumcision outcomes: experience in a developing country setting
    John N Krieger
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Urol Int 78:235-40. 2007
    ..We examined male circumcision outcomes among young adults in an African setting...
  8. doi request reprint Male circumcision and HIV infection risk
    John N Krieger
    Department of Urology, School of Medicine, University of Washington, Seattle, WA 98195, USA
    World J Urol 30:3-13. 2012
    ..This review evaluates the scientific evidence suggesting that male circumcision reduces HIV infection risk in high-risk heterosexual populations...
  9. pmc Epidemiology of prostatitis
    John N Krieger
    Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
    Int J Antimicrob Agents 31:S85-90. 2008
    ..Prostatitis describes a combination of infectious diseases (acute and chronic bacterial prostatitis), chronic pelvic pain syndrome, and asymptomatic inflammation...
  10. pmc Adult male circumcision: effects on sexual function and sexual satisfaction in Kisumu, Kenya
    John N Krieger
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    J Sex Med 5:2610-22. 2008
    ..Male circumcision is being promoted for HIV prevention in high-risk heterosexual populations. However, there is a concern that circumcision may impair sexual function...
  11. ncbi request reprint The NIH Consensus concept of chronic prostatitis/chronic pelvic pain syndrome compared with traditional concepts of nonbacterial prostatitis and prostatodynia
    John N Krieger
    Department of Urology, University of Washington School of Medicine, Box 356510, Seattle, WA 98109, USA
    Curr Urol Rep 3:301-6. 2002
    ..001). The new NIH consensus concept of inflammatory CP/CPPS includes almost twice as many patients as the traditional category of nonbacterial prostatitis...
  12. ncbi request reprint Prostatitis revisited: new definitions, new approaches
    John N Krieger
    Department of Urology, University of Washington School of Medicine, VA Puget Sound Health Care System, Section of Urology 112 GU, 1660 South Columbian Way, Seattle, WA 98108, USA
    Infect Dis Clin North Am 17:395-409. 2003
    ....
  13. ncbi request reprint Bacteria in the chronic prostatitis-chronic pelvic pain syndrome: molecular approaches to critical research questions
    John N Krieger
    Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
    J Urol 167:2574-83. 2002
    ..There is a pressing need to determine the causes and consequences of, and optimal therapy for the chronic prostatitis-chronic pelvic pain syndrome...
  14. ncbi request reprint Symptoms and inflammation in chronic prostatitis/chronic pelvic pain syndrome
    John N Krieger
    Department of Urology, School of Medicine, University of Washington, Seattle, Washington, USA
    Urology 60:959-63. 2002
    ..Patients with CP/CPPS present with characteristic symptoms without bacteriuria. The new National Institutes of Health consensus suggests that CP/CPPS can be divided into inflammatory and noninflammatory categories...
  15. ncbi request reprint Application of real-time polymerase chain reaction technology to detect prostatic bacteria in patients with chronic prostatitis/chronic pelvic pain syndrome
    Satoshi Takahashi
    Department of Urology, University of Washington School of Medicine, 112 GU, VA Puget Sound Health Care System1660 South Columbian Way, WA 98108 1597, Seattle, USA
    World J Urol 21:100-4. 2003
    ..Quantification, speed and specificity make real-time PCR a promising approach for the quantitative detection and identification of prostatic bacteria from CP/CPPS patients...
  16. pmc UTR dinucleotide simple sequence repeat evolution exhibits recurring patterns including regulatory sequence motif replacements
    Donald E Riley
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Gene 429:80-6. 2009
    ..These evolutionary replacements suggest that some diSSRs belong to a broader group of weak-folding repetitive sequences with potential regulatory roles...
  17. ncbi request reprint Simple repeat evolution includes dramatic primary sequence changes that conserve folding potential
    Donald E Riley
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Biochem Biophys Res Commun 355:619-25. 2007
    ..These observations reflect a predictable evolutionary pattern for some common non-coding genomic sequences...
  18. ncbi request reprint Urinary tract infections cranberry juice, underwear, and probiotics in the 21st century
    Jane L Miller
    Department of Urology, University of Washington School of Medicine, Seattle, WA 98195, USA
    Urol Clin North Am 29:695-9. 2002
    ..It is easy to understand this concern because UTIs are common, costly, and cause considerable morbidity...
  19. ncbi request reprint Complications of scrotal surgery for benign conditions
    Mia A Swartz
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Urology 69:616-9. 2007
    ..Frequent complications have been reported after scrotal surgery. We reviewed our experience to determine the complication rates, risk factors, and how our experience might differ from other series...
  20. ncbi request reprint Diverse eukaryotic transcripts suggest short tandem repeats have cellular functions
    Donald E Riley
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Biochem Biophys Res Commun 298:581-6. 2002
    ..These observations suggest that (GATA)n sequences probably function. In many cases, the function may be to encode post-transcriptional signals for mRNAs encoding membrane-associated proteins...
  21. pmc Embryonic nervous system genes predominate in searches for dinucleotide simple sequence repeats flanked by conserved sequences
    Donald E Riley
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Gene 429:74-9. 2009
    ..When flanked by conserved sequences, the self-complementary diSSR (AT)n was also associated with genes expressed in the developing nervous system. Our findings implicate functional roles for diSSRs in nervous system development...
  22. ncbi request reprint Short tandem repeat (STR) replacements in UTRs and introns suggest an important role for certain STRs in gene expression and disease
    Donald E Riley
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Gene 344:203-11. 2005
    ..STR replacements expand the list of STR sequences that may contribute to genetic activity and to disease processes...
  23. pmc Fournier's gangrene: management and mortality predictors in a population based study
    Mathew D Sorensen
    Harborview Injury Prevention and Research Center, University of Washington School of Medicine, Seattle, Washington 98195, USA
    J Urol 182:2742-7. 2009
    ..The Fournier's gangrene literature comes almost exclusively from tertiary referral centers. We used a population based database to evaluate variations in management and outcomes...
  24. pmc Post-prostatic massage fluid/urine as an alternative to semen for studying male genitourinary HIV-1 shedding
    Susan M Graham
    University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Sex Transm Infect 87:232-7. 2011
    ..Because semen collection is often impractical, the acceptability, feasibility and validity of post-prostatic massage fluid/urine (post-PMF/U) was evaluated for studying male genitourinary HIV-1 shedding...
  25. ncbi request reprint Lower genitourinary tract sources of seminal HIV
    Robert W Coombs
    Department of Laboratory Medicine, University of Washington, Seattle, WA 98104 2499, USA
    J Acquir Immune Defic Syndr 41:430-8. 2006
    ..To investigate genital tract sources of HIV-1, we conducted extensive genitourinary sampling of 23 seropositive men without urethritis who shed HIV in their seminal plasma...
  26. ncbi request reprint Counting leukocytes in expressed prostatic secretions from patients with chronic prostatitis/chronic pelvic pain syndrome
    John N Krieger
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98108 1597, USA
    Urology 62:30-4. 2003
    ....
  27. ncbi request reprint X Chromosomal short tandem repeat polymorphisms near the phosphoglycerate kinase gene in men with chronic prostatitis
    Donald E Riley
    Department of Urology, School of Medicine, University of Washington, Seattle, WA 98195, USA
    Biochim Biophys Acta 1586:99-107. 2002
    ..Further investigations involving family studies, larger patient populations, and other control groups may help elucidate this potential genetic predisposition in CP/CPPS...
  28. ncbi request reprint Chronic prostatitis: Charlottesville to Seattle
    John N Krieger
    Department of Urology, University of Washington School of Medicine, Seattle, Washington, USA
    J Urol 172:2557-60. 2004
    ..Since few men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) have culturable bacteria by traditional approaches, we used sensitive molecular methods to determine presence of fastidious microorganisms...
  29. ncbi request reprint Short tandem repeats are associated with diverse mRNAs encoding membrane-targeted proteins
    Donald E Riley
    Department of Research, VA Puget Sound Health Care System, Seattle, Washington, USA
    Bioessays 26:434-44. 2004
    ..001). Similarly, (GU)n was 8 times more common in membrane-function mRNAs than in the total database (P < 0.001). These observations suggest that (AC)n and (GU)n may be UTR signals for some mRNAs encoding membrane-targeted proteins...
  30. ncbi request reprint Simple repeat replacements support similar functions of distinct repeats in inter-species mRNA homologs
    Donald E Riley
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Gene 328:17-24. 2004
    ....
  31. ncbi request reprint Transcribed short tandem repeats occur in couples with strongly preferred registers
    Donald E Riley
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Biochem Biophys Res Commun 305:257-65. 2003
    ..These observations suggest that some transcribed STRs may be functional UTR signals with predictable organization and usage patterns...
  32. ncbi request reprint Overview summary statement. Diagnosis and management of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)
    Anthony J Schaeffer
    Department of Urology, Northwestern University Medical School, Chicago, Illinois, USA
    Urology 60:1-4. 2002
    ....
  33. ncbi request reprint Chronic prostatitis: epidemiology and role of infection
    John N Krieger
    Department of Urology, University of Washington School of Medicine, Seattle, Washington, USA
    Urology 60:8-12; discussion 13. 2002
    ..These data suggest that colonization and/or infection occurs in the prostates of many patients with CP/CPPS. Further molecular research is needed to define the role of bacteria in the etiology of CP/CPPS...
  34. pmc Fournier's Gangrene: population based epidemiology and outcomes
    Mathew D Sorensen
    Harborview Injury Prevention and Research Center, University of Washington School of Medicine, Seattle, Washington 98195, USA
    J Urol 181:2120-6. 2009
    ..Because to our knowledge there are no population based data, we used a national database to investigate the epidemiology of Fournier's gangrene...
  35. doi request reprint Male genital tract compartmentalization of human immunodeficiency virus type 1 (HIV)
    Kurt Diem
    Department of Laboratory Medicine, University of Washington, Seattle, Washington 98195, USA
    AIDS Res Hum Retroviruses 24:561-71. 2008
    ..As such, our study findings are important for understanding the long-term response to antiretroviral therapy, the design of vaccines, and the sexual transmission of HIV...
  36. pmc Pregabalin for the treatment of men with chronic prostatitis/chronic pelvic pain syndrome: a randomized controlled trial
    Michel A Pontari
    Department of Urology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    Arch Intern Med 170:1586-93. 2010
    ..Evidence suggests that the urogenital pain of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) may be neuropathic...
  37. ncbi request reprint Penile cancer: importance of circumcision, human papillomavirus and smoking in in situ and invasive disease
    Janet R Daling
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Int J Cancer 116:606-16. 2005
    ..Circumcision in early childhood may help prevent penile cancer by eliminating phimosis, a significant risk factor for the disease...
  38. doi request reprint Validation of a sham acupuncture procedure in a randomised, controlled clinical trial of chronic pelvic pain treatment
    Shaun Wen Huey Lee
    Department of Urological Surgery, University of Washington, 1660 S Columbian Way, Seattle, WA 98108, USA
    Acupunct Med 29:40-6. 2011
    ..Unfortunately, it is difficult to determine the benefit of acupuncture because few studies have employed controls or had physiological outcome measures...
  39. ncbi request reprint Chronic prostatitis/chronic pelvic pain syndrome: role of alpha blocker therapy
    Shaun Wen Huey Lee
    Department of Urology, University of Washington School of Medicine, Seattle, Wash 98195, USA
    Urol Int 78:97-105. 2007
    ..This article reviews the rationale and data supporting alpha blocker therapy for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), the most common and difficult prostatitis syndrome...
  40. ncbi request reprint Urinary tract infections: what's new?
    John N Krieger
    Department of Urology, University of Washington, School of Medicine, Seattle, USA
    J Urol 168:2351-8. 2002
    ..This review provides practicing urologists with important basic information about urinary tract infections (UTIs) that can be applied to everyday clinical problems...
  41. doi request reprint Adverse impact of sexual dysfunction in chronic prostatitis/chronic pelvic pain syndrome
    Shaun Wen Huey Lee
    School of Pharmaceutical Sciences, University of Science Malaysia, Penang, Malaysia
    Urology 71:79-84. 2008
    ..To examine the prevalence, characteristics, and impact of sexual dysfunction in our primary care referral population...
  42. doi request reprint Acupuncture versus sham acupuncture for chronic prostatitis/chronic pelvic pain
    Shaun Wen Huey Lee
    School of Pharmaceutical Science, University of Science, Malaysia
    Am J Med 121:79.e1-7. 2008
    ..Available therapies offer little or no proven benefit. Because acupuncture represents an attractive "natural" therapy, we compared the efficacy of acupuncture to sham acupuncture for CP/CPPS...
  43. ncbi request reprint Pentosan polysulfate sodium therapy for men with chronic pelvic pain syndrome: a multicenter, randomized, placebo controlled study
    J Curtis Nickel
    Department of Urology, Queens University, Kingston, Ontario, Canada
    J Urol 173:1252-5. 2005
    ..We evaluated the efficacy and tolerability of pentosan polysulfate sodium (PPS) for the treatment of men with chronic pelvic pain syndrome (CPPS), National Institutes of Health (NIH) category III...
  44. ncbi request reprint Reliability and validity of the National Institutes of Health: Chronic Prostatitis Symptom Index in a Malaysian population
    Phaik Yeong Cheah
    School of Pharmaceutical Sciences, University of Science Malaysia, Penang, Malaysia
    World J Urol 24:79-87. 2006
    ..Short-term TR and discriminant validity were excellent for all three versions. However, long-term TR was only moderate, which might reflect variation in patients' perceptions of symptoms over time...
  45. ncbi request reprint Initial, long-term, and durable responses to terazosin, placebo, or other therapies for chronic prostatitis/chronic pelvic pain syndrome
    Phaik Yeong Cheah
    University of Science Malaysia School of Pharmaceutical Sciences, Penang, Malaysia
    Urology 64:881-6. 2004
    ..To evaluate the initial, long-term, and durable response rates to terazosin, placebo, or other therapies in patients with chronic prostatitis/chronic pelvic pain syndrome...
  46. ncbi request reprint The problem with prostatitis. What do we know? What do we need to know?
    John N Krieger
    J Urol 172:432-3. 2004
  47. ncbi request reprint Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial
    Robert C Bailey
    Division of Epidemiology and Biostatistics, University of Illinois at Chicago, Chicago, IL 60612, USA
    Lancet 369:643-56. 2007
    ..Our aim was to determine whether male circumcision had a protective effect against HIV infection, and to assess safety and changes in sexual behaviour related to this intervention...
  48. ncbi request reprint Chronic prostatitis: symptom survey with follow-up clinical evaluation
    Phaik Yeong Cheah
    University of Science Malaysia School of Pharmaceutical Sciences, Penang, Malaysia
    Urology 61:60-4. 2003
    ..quot;..
  49. ncbi request reprint Terazosin therapy for chronic prostatitis/chronic pelvic pain syndrome: a randomized, placebo controlled trial
    Phaik Yeong Cheah
    School of Pharmaceutical Sciences, University of Science Malaysia, Penang, Malaysia
    J Urol 169:592-6. 2003
    ..We evaluate terazosin therapy for chronic prostatitis/chronic pelvic pain syndrome...
  50. ncbi request reprint Prostatitis: ancient history and new horizons
    John N Krieger
    World J Urol 21:51-3. 2003
  51. ncbi request reprint Demographic and clinical characteristics of chronic prostatitis: prospective comparison of the University of Sciences Malaysia Cohort with the United States National Institutes of Health Cohort
    Shaun Wen Huey Lee
    School of Pharmaceutical Sciences, University of Sciences Malaysia, Penang, Malaysia
    J Urol 177:153-7; discussion 158. 2007
    ..We compared demographic and clinical characteristics of the University of Sciences Malaysia Chronic Prostatitis Cohort to the United States National Institutes of Health Chronic Prostatitis Cohort...

Research Grants24

  1. UROLOGICAL STUDIES OF IDEOPATHIC LOWER TRACT SYNDROMES
    JOHN KRIEGER; Fiscal Year: 2000
    ..This study will provide insight into the pathophysiology of chronic prostatitis and the clinical utility of cystoscopy under anaesthesia for evaluating patients. ..
  2. MALE GENITAL TRACT RESERVOIRS AND VIRAL SHEDDING
    JOHN KRIEGER; Fiscal Year: 2004
    ..Thus, controlling one genital tract virus may limit viral-viral interactions, reduce the viral burden in semen, and decrease the sexual transmission of other viruses. ..
  3. Urological Studies of Ideopathic Lower Tract Syndrome
    JOHN KRIEGER; Fiscal Year: 2005
    ..These studies will determine if EPS or SFA can be used to identify prostatic bacteria and may result in clinical methods for non-invasive diagnosis of prostatic infection. ..
  4. UROLOGICAL STUDIES OF IDIOPATHIC LOWER TRACT SYNDROMES
    JOHN KRIEGER; Fiscal Year: 1991
    ..These studies will elucidate fundamental aspects of pathogenesis and facilitate recommendations for urological evaluation and treatment of millions of men annually in the United States...
  5. UROLOGICAL STUDIES OF IDIOPATHIC LOWER TRACT SYNDROMES
    JOHN KRIEGER; Fiscal Year: 1993
    ..Understanding the etiology of common lower tract syndromes will improve urological evaluation and treatment of millions of men annually in the U.S...
  6. UW/USM Chronic Prostatitis CRC
    JOHN KRIEGER; Fiscal Year: 2007
    ..Potential outcomes include: symptom indexes (e.g., the NIH-CPSI), urodynamics and inflammation. ..