L J Kricka

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Translating genes into health
    Larry J Kricka
    Department of Pathology and Laboratory Medicine at University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Nat Genet 45:4-5. 2013
  2. ncbi Microchips: an all-language literature survey including books and patents
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Clin Chem 48:1620-2. 2002
  3. ncbi Miniaturized detection technology in molecular diagnostics
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 7 103 Founders Pavilion, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Expert Rev Mol Diagn 5:549-59. 2005
  4. ncbi Bibliography. Luminescence literature. GFP and imaging 2002 literature
    L J Kricka
    Luminescence 20:97-102. 2005
  5. ncbi Microchip PCR
    L J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Anal Bioanal Chem 377:820-5. 2003
  6. ncbi Current perspectives in protein array technology
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Ann Clin Biochem 43:457-67. 2006
  7. ncbi Luminescence Literature. Electrochemiluminescence 1999-2002
    L J Kricka
    Luminescence 19:121-7. 2004
  8. ncbi Stains, labels and detection strategies for nucleic acids assays
    Larry J Kricka
    Department of Pathology, University of Pennsylvania, Philadelphia 19104, USA
    Ann Clin Biochem 39:114-29. 2002
  9. ncbi Validation and quality control of protein microarray-based analytical methods
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Mol Biotechnol 38:19-31. 2008
  10. ncbi Commentary: interferences in laboratory tests
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Clin Chem 54:1245. 2008

Collaborators

Detail Information

Publications45

  1. ncbi Translating genes into health
    Larry J Kricka
    Department of Pathology and Laboratory Medicine at University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Nat Genet 45:4-5. 2013
    ..These challenges and opportunities for genomic medicine were central themes of the Golden Helix Symposium held in Turin, Italy, 18-21 April 2012...
  2. ncbi Microchips: an all-language literature survey including books and patents
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Clin Chem 48:1620-2. 2002
  3. ncbi Miniaturized detection technology in molecular diagnostics
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 7 103 Founders Pavilion, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Expert Rev Mol Diagn 5:549-59. 2005
    ..These nanofabricated objects provide new tools for sequencing of nucleic acids and rapid, multiplexed, nucleic acid detection...
  4. ncbi Bibliography. Luminescence literature. GFP and imaging 2002 literature
    L J Kricka
    Luminescence 20:97-102. 2005
  5. ncbi Microchip PCR
    L J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Anal Bioanal Chem 377:820-5. 2003
    ..It also discusses the problems attributable to surface chemistry of microchip components (inhibition of PCR), and the static and dynamic surface passivation strategies developed for the solution of these difficulties..
  6. ncbi Current perspectives in protein array technology
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Ann Clin Biochem 43:457-67. 2006
    ..Important requirements for the quality control and quality assurance of protein microarray assays as they move from the research environment into routine clinical application are also discussed...
  7. ncbi Luminescence Literature. Electrochemiluminescence 1999-2002
    L J Kricka
    Luminescence 19:121-7. 2004
  8. ncbi Stains, labels and detection strategies for nucleic acids assays
    Larry J Kricka
    Department of Pathology, University of Pennsylvania, Philadelphia 19104, USA
    Ann Clin Biochem 39:114-29. 2002
    ....
  9. ncbi Validation and quality control of protein microarray-based analytical methods
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Mol Biotechnol 38:19-31. 2008
    ..With the development of appropriate quality control and assurance measures, we anticipate protein microarray-based assays will be of substantial benefit in the future practice of laboratory medicine...
  10. ncbi Commentary: interferences in laboratory tests
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Clin Chem 54:1245. 2008
  11. ncbi Luminescence literature. GFP and imaging 2001 literature
    L J Kricka
    Luminescence 20:57-62. 2005
  12. ncbi Luminescence literature
    L J Kricka
    Luminescence 19:359-67. 2004
  13. ncbi Analytical ancestry: "firsts" in fluorescent labeling of nucleosides, nucleotides, and nucleic acids
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Clin Chem 55:670-83. 2009
    ..The inherent fluorescent properties of nucleosides, nucleotides, and nucleic acids are limited, and thus the need has arisen for fluorescent labeling of these molecules for a variety of analytical applications...
  14. ncbi Analytical ancestry: evolution of the array in analysis
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Clin Chem 56:1797-803. 2010
    ..Macro-, micro-, and nanosized arrays of test sites at various densities have emerged as important types of analytical devices in response to the need for high volume parallel analysis in both the research and the clinical laboratory...
  15. ncbi International year of Chemistry 2011. A guide to the history of clinical chemistry
    Larry J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, USA
    Clin Chem 57:1118-26. 2011
    ..This review was written as part of the celebration of the International Year of Chemistry 2011...
  16. ncbi Luminescence literature. Green fluorescent protein (GFP)--2001 literature
    L J Kricka
    Luminescence 19:296-318. 2004
  17. ncbi Luminescence literature. Sonoluminescence 1999-2002
    L J Kricka
    Luminescence 19:116-21. 2004
  18. ncbi Agilent 2100 bioanalyzer for restriction fragment length polymorphism analysis of the Campylobacter jejuni flagellin gene
    I Nachamkin
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4283, USA
    J Clin Microbiol 39:754-7. 2001
    ..Overall, the bioanalyzer has the potential to replace conventional RFLP analysis by gel electrophoresis, but improvements in the chip separation are needed...
  19. ncbi Microchip module for blood sample preparation and nucleic acid amplification reactions
    P K Yuen
    Department of Pathology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Genome Res 11:405-12. 2001
    ..The microchip module provides a convenient means to simplify nucleic acid analyses by integrating two key steps in genetic testing procedures, cell isolation and PCR and promises to be adaptable for additional types of integrated assays...
  20. ncbi Diagnosis of Duchenne/Becker muscular dystrophy and quantitative identification of carrier status by use of entangled solution capillary electrophoresis
    P Fortina
    Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine 19104 4318, USA
    Clin Chem 43:745-51. 1997
    ....
  21. ncbi Diagnostic challenges for multiplexed protein microarrays
    Stephen R Master
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Drug Discov Today 11:1007-11. 2006
    ....
  22. ncbi Molecular diagnostics: hurdles for clinical implementation
    Paolo Fortina
    Dept of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, 310 C Abramson Pediatric Research Center, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Trends Mol Med 8:264-6. 2002
    ..Together with proteomic-based testing, these advances will improve molecular diagnostic testing and will present additional challenges for implementing such testing in health care settings...
  23. ncbi Human anti-animal antibody interferences in immunological assays
    L J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
    Clin Chem 45:942-56. 1999
    ..The scope and significance of human anti-animal antibody interference in immunological assays is reviewed with an emphasis on human anti-animal immunoglobulins, particularly human anti-mouse antibodies (HAMAs)...
  24. ncbi Microchips, microarrays, biochips and nanochips: personal laboratories for the 21st century
    L J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Clin Chim Acta 307:219-23. 2001
    ..The next level of miniaturization is the nanochip (nanometer-sized features) and the technological foundation for these futuristic devices is discernable in nanotubes and self-assembling molecular structures...
  25. ncbi Validation and quality control of protein microarray-based analytical methods
    Larry J Kricka
    Department of Pahology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Methods Mol Med 114:233-55. 2005
    ..The special considerations for protein microarrays as they transition from research into routine clinical analysis and the resulting quality control of clinical test results generated using such devices are discussed...
  26. ncbi Micromachined analytical devices: microchips for semen testing
    L J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia 19104, USA
    J Pharm Biomed Anal 15:1443-7. 1997
    ..This study demonstrates the feasibility of microchips for sperm motility testing and suggests that this technique would be applicable to the study of other types of motile cells...
  27. ncbi Analysis of ligase chain reaction products amplified in a silicon-glass chip using capillary electrophoresis
    J Cheng
    Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
    J Chromatogr A 732:151-8. 1996
    ..CE-LIF analysis is ideally suited to examination of micro-LCR amplification with high throughput. The technologies may find medical uses in disease diagnosis and research...
  28. ncbi Genotyping on a thermal gradient DNA chip
    Tomoharu Kajiyama
    Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Genome Res 13:467-75. 2003
    ..Unambiguous typing was achieved for clinically relevant loci within the factor VII and hemochromatosis genes...
  29. ncbi Miniaturization of analytical systems
    L J Kricka
    Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia 19104, USA
    Clin Chem 44:2008-14. 1998
    ..Resolution of these issues will be important for the long-term success of microminiature analyzers; in the meantime, the scope, diversity, and rate of progress in the development of these devices promises products in the near future...
  30. ncbi Bioconjugation of alkaline phosphatase to mechanically processed, aqueous suspendible electrospun polymer nanofibers for use in chemiluminescent detection assays
    Sonny S Mark
    Center for Biomedical Micro and Nanotechnology, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Macromol Biosci 8:484-98. 2008
    ....
  31. ncbi Mutation detection using ligase chain reaction in passivated silicon-glass microchips and microchip capillary electrophoresis
    Xing Jian Lou
    University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Biotechniques 37:392, 394, 396-8. 2004
    ..Ligated primers were detected and quantified simply and conveniently using microchip capillary electrophoresis...
  32. ncbi Increased amplification efficiency of microchip-based PCR by dynamic surface passivation
    Xing Jian Lou
    University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Biotechniques 36:248-52. 2004
    ..It can also be used in combination with static passivation (silicon oxide surface layer) to further improve PCR performance using silicon-glass PCR chips...
  33. ncbi Clinical analysis by microchip capillary electrophoresis
    Sam F Y Li
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Clin Chem 52:37-45. 2006
    ..To put into perspective its potential, we briefly compare microchip CE with conventional CE and review developments in this technique that may be useful in diagnosis of major diseases...
  34. ncbi Nanobiotechnology: the promise and reality of new approaches to molecular recognition
    Paolo Fortina
    Center for Translational Medicine, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Trends Biotechnol 23:168-73. 2005
    ..We also speculate on further pathways in nanotechnology development and the emergence of order in this somewhat chaotic, yet promising, new field...
  35. ncbi Biofunctionalization of aqueous dispersed, alumina membrane-templated polymer nanorods for use in enzymatic chemiluminescence assays
    Sonny S Mark
    Center for Biomedical Micro and Nanotechnology, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Colloids Surf B Biointerfaces 65:230-8. 2008
    ..5. To the best of our knowledge, this study represents the first report examining the preparation of aqueous dispersed, AAO-templated polymer nanorods for potential application as enzyme scaffolds in chemiluminescent-based assay systems...
  36. ncbi Fabrication of plastic microchips by hot embossing
    Larry J Kricka
    Departments of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Lab Chip 2:1-4. 2002
    ..This microfabrication technique offers a viable and potentially high-volume low cost production method for fabricating transparent microchips for analytical applications...
  37. ncbi Prospects for nano- and microtechnologies in clinical point-of-care testing
    Jason Y Park
    Center for Biomedical Micro and Nanotechnology, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, USA
    Lab Chip 7:547-9. 2007
  38. ncbi Nanotechnology and immunoassay
    Samuel I Stolper
    Clin Chem 53:1874. 2007
  39. ncbi Nanotechnology and applications: an all-language literature survey including books and patents
    Larry J Kricka
    Clin Chem 48:662-5. 2002
  40. ncbi Improving healthcare accessibility through point-of-care technologies
    Christopher P Price
    Department of Clinical Biochemistry, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Clin Chem 53:1665-75. 2007
    ..A hypothesis has been developed that testing closer to the point at which care is delivered may reduce fragmentation of care and improve outcomes...
  41. ncbi Additive-aggravated assays: an authoritative answer
    Larry J Kricka
    Clin Chem 51:1767. 2005
  42. ncbi Protein microarrays: a literature survey
    Larry J Kricka
    Clin Chem 49:2109. 2003
  43. ncbi Micropillar array chip for integrated white blood cell isolation and PCR
    Nicholas J Panaro
    Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Biomol Eng 21:157-62. 2005
    ..Reproducible on-chip PCR was achieved using white blood cell preparations isolated from whole human blood pumped through the chip...
  44. ncbi Surface effects on PCR reactions in multichip microfluidic platforms
    Nicholas J Panaro
    Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Founders Pavilion, Philadelphia, PA 19104, USA
    Biomed Microdevices 6:75-80. 2004
    ..These studies identified several common plastics, plastic tubing, and disposable syringes which were compatible with the PCR reaction...
  45. ncbi Fifty years of molecular (DNA/RNA) diagnostics
    Thomas R Gingeras
    Affymetrix, Inc, Santa Clara, CA, USA
    Clin Chem 51:661-71. 2005