Dimitry N Krementsov

Summary

Affiliation: University of Vermont
Country: USA

Publications

  1. pmc Exacerbation of autoimmune neuroinflammation by dietary sodium is genetically controlled and sex specific
    Dimitry N Krementsov
    Department of Medicine, Immunobiology Program, University of Vermont, Burlington, Vermont, USA and Department of Pathology, Dartmouth Medical School, Hanover, New Hampshire, USA
    FASEB J 29:3446-57. 2015
  2. pmc Tetraspanins regulate cell-to-cell transmission of HIV-1
    Dimitry N Krementsov
    Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA
    Retrovirology 6:64. 2009
  3. pmc Formation of syncytia is repressed by tetraspanins in human immunodeficiency virus type 1-producing cells
    Jia Weng
    Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA
    J Virol 83:7467-74. 2009
  4. pmc HIV-1 assembly differentially alters dynamics and partitioning of tetraspanins and raft components
    Dimitry N Krementsov
    Graduate Program in Cell and Molecular Biology, University of Vermont, Burlington, VT 05405, USA
    Traffic 11:1401-14. 2010
  5. pmc Human immunodeficiency virus type 1 and influenza virus exit via different membrane microdomains
    Sandhya Khurana
    Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA
    J Virol 81:12630-40. 2007
  6. pmc The Y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease
    Laure K Case
    Department of Medicine, University of Vermont, Burlington, Vermont 05405, USA
    Genome Res 23:1474-85. 2013
  7. pmc Histamine H₂ receptor signaling × environment interactions determine susceptibility to experimental allergic encephalomyelitis
    Naresha Saligrama
    1Immunobiology Program, C331 Given Medical Building, University of Vermont, Burlington, VT 05405, USA
    FASEB J 28:1898-909. 2014
  8. pmc Sex-specific control of central nervous system autoimmunity by p38 mitogen-activated protein kinase signaling in myeloid cells
    Dimitry N Krementsov
    Department of Medicine, Immunobiology Program, University of Vermont, Burlington, VT
    Ann Neurol 75:50-66. 2014
  9. pmc Histamine H(3) receptor integrates peripheral inflammatory signals in the neurogenic control of immune responses and autoimmune disease susceptibility
    Dimitry N Krementsov
    Department of Medicine, Immunobiology Program, University of Vermont, Burlington, Vermont, USA
    PLoS ONE 8:e62743. 2013
  10. pmc Mapping of tetraspanin-enriched microdomains that can function as gateways for HIV-1
    Sascha Nydegger
    Graduate Program in Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA
    J Cell Biol 173:795-807. 2006

Collaborators

Detail Information

Publications14

  1. pmc Exacerbation of autoimmune neuroinflammation by dietary sodium is genetically controlled and sex specific
    Dimitry N Krementsov
    Department of Medicine, Immunobiology Program, University of Vermont, Burlington, Vermont, USA and Department of Pathology, Dartmouth Medical School, Hanover, New Hampshire, USA
    FASEB J 29:3446-57. 2015
    ..Our results demonstrate that the effects of dietary sodium on autoimmune neuroinflammation are sex specific, genetically controlled, and CNS mediated...
  2. pmc Tetraspanins regulate cell-to-cell transmission of HIV-1
    Dimitry N Krementsov
    Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA
    Retrovirology 6:64. 2009
    ..Here we used overexpression and knockdown approaches to address this question...
  3. pmc Formation of syncytia is repressed by tetraspanins in human immunodeficiency virus type 1-producing cells
    Jia Weng
    Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA
    J Virol 83:7467-74. 2009
    ..Overall, these data establish tetraspanins as negative regulators of HIV-1-induced cell-cell fusion, and they start delineating the requirements for this regulation...
  4. pmc HIV-1 assembly differentially alters dynamics and partitioning of tetraspanins and raft components
    Dimitry N Krementsov
    Graduate Program in Cell and Molecular Biology, University of Vermont, Burlington, VT 05405, USA
    Traffic 11:1401-14. 2010
    ..Importantly, our findings support the emerging concept that cellular and viral components, instead of clustering at preexisting microdomain platforms, direct the formation of distinct domains for the execution of specific functions...
  5. pmc Human immunodeficiency virus type 1 and influenza virus exit via different membrane microdomains
    Sandhya Khurana
    Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA
    J Virol 81:12630-40. 2007
    ..Altogether, these data strongly suggest that the bimodal egress of these two pathogenic viruses, like their entry into target cells, is guided by specific sets of host cell proteins...
  6. pmc The Y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease
    Laure K Case
    Department of Medicine, University of Vermont, Burlington, Vermont 05405, USA
    Genome Res 23:1474-85. 2013
    ..Thus, as in Drosophila, these data establish the mammalian ChrY as a member of the regulatory genome due to its ability to epigenetically regulate genome-wide gene expression in immune cells. ..
  7. pmc Histamine H₂ receptor signaling × environment interactions determine susceptibility to experimental allergic encephalomyelitis
    Naresha Saligrama
    1Immunobiology Program, C331 Given Medical Building, University of Vermont, Burlington, VT 05405, USA
    FASEB J 28:1898-909. 2014
    ..Thus, the regulation of encephalitogenic T-cell responses and EAE susceptibility by H2R signaling in CD4(+) T cells is dependent on gene × environment interactions...
  8. pmc Sex-specific control of central nervous system autoimmunity by p38 mitogen-activated protein kinase signaling in myeloid cells
    Dimitry N Krementsov
    Department of Medicine, Immunobiology Program, University of Vermont, Burlington, VT
    Ann Neurol 75:50-66. 2014
    ..Investigators have described p38 mitogen-activated protein kinase (MAPK) as a key regulator of inflammatory responses in autoimmunity, but its role in the sexual dimorphism in MS or MS models remains unexplored...
  9. pmc Histamine H(3) receptor integrates peripheral inflammatory signals in the neurogenic control of immune responses and autoimmune disease susceptibility
    Dimitry N Krementsov
    Department of Medicine, Immunobiology Program, University of Vermont, Burlington, Vermont, USA
    PLoS ONE 8:e62743. 2013
    ..Pharmacological targeting of H(3)R may therefore be useful in preventing the development and formation of new lesions in MS, thereby limiting disease progression...
  10. pmc Mapping of tetraspanin-enriched microdomains that can function as gateways for HIV-1
    Sascha Nydegger
    Graduate Program in Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA
    J Cell Biol 173:795-807. 2006
    ....
  11. pmc Environmental factors acting during development to influence MS risk: insights from animal studies
    Dimitry N Krementsov
    Department of Medicine, University of Vermont, Burlington, VT, USA
    Mult Scler 19:1684-9. 2013
    ..Nonetheless, studies in this area so far are few. In this review, we summarize the insights gleaned from studies that test environmental influences in animal models of MS, with a particular focus on gestational and early life exposures. ..
  12. pmc Studies in experimental autoimmune encephalomyelitis do not support developmental bisphenol a exposure as an environmental factor in increasing multiple sclerosis risk
    Dimitry N Krementsov
    Department of Medicine, Immunobiology Program, University of Vermont, Burlington, Vermont 05405, USA
    Toxicol Sci 135:91-102. 2013
    ..Overall, our results do not support gestational BPA exposure as a significant contributor to the increasing female MS risk. ..
  13. pmc The emerging role of p38 mitogen-activated protein kinase in multiple sclerosis and its models
    Dimitry N Krementsov
    Department of Medicine, Immunobiology Program, University of Vermont, Burlington, Vermont, USA
    Mol Cell Biol 33:3728-34. 2013
    ....
  14. pmc Histamine H4 receptor optimizes T regulatory cell frequency and facilitates anti-inflammatory responses within the central nervous system
    Roxana del Rio
    Department of Medicine, Immunobiology Program, University of Vermont, Burlington, VT 05405, USA
    J Immunol 188:541-7. 2012
    ..Moreover, the lack of H(4)R leads to an impairment of an anti-inflammatory response due to fewer T(R) cells in the CNS during the acute phase of the disease and an increase in the proportion of Th17 cells...