N E Krebs

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi request reprint Bone mineral density changes during lactation: maternal, dietary, and biochemical correlates
    N F Krebs
    Department of Pediatrics, University of Colorado School of Medicine, Denver 80262, USA
    Am J Clin Nutr 65:1738-46. 1997
  2. ncbi request reprint Comprehensive integration of nutrition into medical training
    Nancy F Krebs
    Department of Pediatrics, University of Colorado School of Medicine, 4200 East Ninth Avenue, Box C225, Denver, CO 80262, USA
    Am J Clin Nutr 83:945S-950S. 2006
  3. ncbi request reprint Screening for overweight in children and adolescents: a call to action
    Nancy F Krebs
    Department of Pediatrics, University of Colorado Health Sciences Center School of Medicine Denver, CO 80262 0001, USA
    Pediatrics 116:238-9. 2005
  4. ncbi request reprint Exchangeable zinc pool size at birth is smaller in small-for-gestational-age than in appropriate-for-gestational-age preterm infants
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO 80262, USA
    Am J Clin Nutr 84:1340-3. 2006
  5. ncbi request reprint Food choices to meet nutritional needs of breast-fed infants and toddlers on mixed diets
    Nancy F Krebs
    University of Colorado Health Science Center, Department of Pediatrics, Denver, CO 80262 0001, USA
    J Nutr 137:511S-517S. 2007
  6. ncbi request reprint Exchangeable zinc pool size in infants is related to key variables of zinc homeostasis
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Nutr 133:1498S-501S. 2003
  7. ncbi request reprint Complementary feeding: clinically relevant factors affecting timing and composition
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO 80252, USA
    Am J Clin Nutr 85:639S-645S. 2007
  8. ncbi request reprint Meat as a first complementary food for breastfed infants: feasibility and impact on zinc intake and status
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA
    J Pediatr Gastroenterol Nutr 42:207-14. 2006
  9. ncbi request reprint Zinc supplementation during lactation
    N F Krebs
    Center for Human Nutrition, University of Colorado School of Medicine, Denver 80262, USA
    Am J Clin Nutr 68:509S-512S. 1998
  10. ncbi request reprint Bioavailability of dietary supplements and impact of physiologic state: infants, children and adolescents
    N F Krebs
    Department of Pediatrics, University of Colorado School of Medicine, Denver, Colorado 80262, USA
    J Nutr 131:1351S-4S. 2001

Research Grants

Collaborators

Detail Information

Publications51

  1. ncbi request reprint Bone mineral density changes during lactation: maternal, dietary, and biochemical correlates
    N F Krebs
    Department of Pediatrics, University of Colorado School of Medicine, Denver 80262, USA
    Am J Clin Nutr 65:1738-46. 1997
    ..The results also suggest that the bone loss may be attenuated by a generous dietary ratio of calcium to protein...
  2. ncbi request reprint Comprehensive integration of nutrition into medical training
    Nancy F Krebs
    Department of Pediatrics, University of Colorado School of Medicine, 4200 East Ninth Avenue, Box C225, Denver, CO 80262, USA
    Am J Clin Nutr 83:945S-950S. 2006
    ..Finally, a coordinator is needed to monitor the many "fronts" of the integrated nutrition curriculum and to continue networking and program implementation...
  3. ncbi request reprint Screening for overweight in children and adolescents: a call to action
    Nancy F Krebs
    Department of Pediatrics, University of Colorado Health Sciences Center School of Medicine Denver, CO 80262 0001, USA
    Pediatrics 116:238-9. 2005
  4. ncbi request reprint Exchangeable zinc pool size at birth is smaller in small-for-gestational-age than in appropriate-for-gestational-age preterm infants
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO 80262, USA
    Am J Clin Nutr 84:1340-3. 2006
    ..Small-for-gestational-age (SGA) infants are susceptible to postnatal zinc deficiency, but whether this susceptibility is due to intrauterine factors or to high postnatal growth requirements is unknown...
  5. ncbi request reprint Food choices to meet nutritional needs of breast-fed infants and toddlers on mixed diets
    Nancy F Krebs
    University of Colorado Health Science Center, Department of Pediatrics, Denver, CO 80262 0001, USA
    J Nutr 137:511S-517S. 2007
    ..In contrast to current practices in both developed and developing countries, meats should be considered as an early complementary food for breast-fed infants to provide essential micronutrients...
  6. ncbi request reprint Exchangeable zinc pool size in infants is related to key variables of zinc homeostasis
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Nutr 133:1498S-501S. 2003
    ..We conclude that the amount of absorbed zinc is not tightly regulated, and that endogenous fecal zinc is dependent on and responsive to the zinc status of the organism...
  7. ncbi request reprint Complementary feeding: clinically relevant factors affecting timing and composition
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO 80252, USA
    Am J Clin Nutr 85:639S-645S. 2007
    ....
  8. ncbi request reprint Meat as a first complementary food for breastfed infants: feasibility and impact on zinc intake and status
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA
    J Pediatr Gastroenterol Nutr 42:207-14. 2006
    ..This study was undertaken to assess the feasibility and effects of consuming either meat or iron-fortified infant cereal as the first complementary food...
  9. ncbi request reprint Zinc supplementation during lactation
    N F Krebs
    Center for Human Nutrition, University of Colorado School of Medicine, Denver 80262, USA
    Am J Clin Nutr 68:509S-512S. 1998
    ..The studies that have examined the zinc status of breast-fed infants are also reviewed...
  10. ncbi request reprint Bioavailability of dietary supplements and impact of physiologic state: infants, children and adolescents
    N F Krebs
    Department of Pediatrics, University of Colorado School of Medicine, Denver, Colorado 80262, USA
    J Nutr 131:1351S-4S. 2001
    ....
  11. ncbi request reprint Zinc metabolism and homeostasis: the application of tracer techniques to human zinc physiology
    N E Krebs
    Department of Pediatrics, University of Colorado School of Medicine, Denver, USA
    Biometals 14:397-412. 2001
    ....
  12. ncbi request reprint Assessment of child and adolescent overweight and obesity
    Nancy F Krebs
    Department of Pediatrics, University of Colorado School of Medicine, 4200 E Ninth Ave, Box C225, Denver, CO 80262, USA
    Pediatrics 120:S193-228. 2007
    ..With this information, clinicians should find themselves better equipped to face the challenges of assessing childhood overweight and obesity accurately...
  13. ncbi request reprint Dysprosium as a nonabsorbable fecal marker in studies of zinc homeostasis
    Xiao Yang Sheng
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Clin Nutr 82:1017-23. 2005
    ..Dysprosium is a nonabsorbable rare earth element that has had successful application as a marker for fecal excretion of unabsorbed zinc...
  14. ncbi request reprint Zinc homeostasis in Malawian children consuming a high-phytate, maize-based diet
    Mark J Manary
    Department of Pediatrics, Washington University School of Medicine, St Louis, USA
    Am J Clin Nutr 75:1057-61. 2002
    ..The gastrointestinal tract plays a central role in absorbing and conserving zinc, yet it has not been carefully studied in such children...
  15. pmc Zinc bioavailability and homeostasis
    K Michael Hambidge
    Department of Pediatrics, Section of Nutrition, University of Colorado Denver, Denver, CO, USA
    Am J Clin Nutr 91:1478S-1483S. 2010
    ..The effects of phytate on intestinal losses of endogenous zinc merit further investigation but are probably not of the same magnitude as its inhibitory effects on absorption of exogenous zinc...
  16. ncbi request reprint Zinc absorption from a low-phytic acid maize
    Christina L Adams
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver 80220, USA
    Am J Clin Nutr 76:556-9. 2002
    ..These low-phytic acid grains provide a strategy for improving the mineral (eg, zinc) status in populations that are dependent on grains, including maize (Zea mays L.), as major dietary staples...
  17. ncbi request reprint Meat as an early complementary food for infants: implications for macro- and micronutrient intakes
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Denver, Colorado, USA
    Nestle Nutr Workshop Ser Pediatr Program 60:221-9; discussion 229-33. 2007
    ..This pattern of macronutrient intake is contrary to that of the period when the human genome evolved, and may influence the metabolic profile in young children, especially under conditions of nutritional abundance...
  18. ncbi request reprint Zinc absorption as a function of the dose of zinc sulfate in aqueous solution
    Cuong D Tran
    Section of Nutrition, Department of Pediatrics, The University of Colorado Health Science Center, Denver, USA
    Am J Clin Nutr 80:1570-3. 2004
    ..Zinc supplements are used extensively in medicine and research and for public health purposes in the prevention and treatment of zinc deficiency. However, little is known about the efficiency of zinc utilization after different doses...
  19. ncbi request reprint Relationships among plasma zinc, plasma prolactin, milk transfer, and milk zinc in lactating women
    Nancy F Krebs
    University of Colorado Cancer Center, Denver 80262, USA
    J Hum Lact 23:179-83. 2007
    ..67, P<.001) and 7 months (r=.53, P<.01), consistent with PRL role in lactation maintenance. Studies including zinc-deficient lactating women are required to clarify the interrelationships between zinc status and PRL secretion...
  20. pmc A mathematical model of zinc absorption in humans as a function of dietary zinc and phytate
    Leland V Miller
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Nutr 137:135-41. 2007
    ..The model was judged to be valid and of immediate value for studying and predicting absorption. A version of the model incorporating a passive absorption mechanism was not supported by the available data...
  21. pmc Dietary reference intakes for zinc may require adjustment for phytate intake based upon model predictions
    K Michael Hambidge
    Department of Pediatrics, Section of Nutrition, University of Colorado, School of Medicine, Denver, CO 80262, USA
    J Nutr 138:2363-6. 2008
    ..4 mg Zn/d. Extrapolation of the model suggested, for example, that with 900 mg/d phytate, 100 mg dietary Zn is required to attain 6.4 mg absorbed Zn/d. Experimental studies with higher Zn intakes are required to test these predictions...
  22. ncbi request reprint Zinc deficiency: a special challenge
    K Michael Hambidge
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80220, USA
    J Nutr 137:1101-5. 2007
    ..Barriers to acceptability and availability of affordable meat are considered, but these are neither universal nor irresolvable in all populations...
  23. pmc Zinc absorption during late pregnancy in rural southern Ethiopia
    K Michael Hambidge
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO, USA
    Am J Clin Nutr 84:1102-6. 2006
    ..Little is yet known about zinc absorption in late pregnancy, and no information on absorption from the total diet is available...
  24. ncbi request reprint Measurements of zinc absorption: application and interpretation in research designed to improve human zinc nutriture
    K Michael Hambidge
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Box C225, 4200 E 9th Av, Denver, Colorado, 80262, USA
    Int J Vitam Nutr Res 75:385-93. 2005
    ..They also suggest the potential utility of measurements of the quantity of zinc absorbed when evaluating the zinc status of populations...
  25. ncbi request reprint Intestinal excretion of endogenous zinc in Guatemalan school children
    K Michael Hambidge
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Nutr 137:1747-9. 2007
    ..Supported by other recent childhood data, these results suggest that the current estimates of EFZ(PR) used in the calculation of Zn requirements for children are misleadingly low...
  26. ncbi request reprint Changes in zinc absorption during development
    K Michael Hambidge
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Pediatr 149:S64-8. 2006
    ..Normal homeostatic mechanisms in the premature infant prevented efficient absorption of the quantity of Zn required or/and optimal conservation of endogenous Zn...
  27. ncbi request reprint Zinc and breastfed infants: if and when is there a risk of deficiency?
    Nancy F Krebs
    University of Colorado, School of Medicine, Denver 80262, USA
    Adv Exp Med Biol 503:69-75. 2002
    ....
  28. ncbi request reprint Zinc absorption from low-phytate hybrids of maize and their wild-type isohybrids
    K Michael Hambidge
    University of Colorado Health Sciences Center, Department of Pediatrics, Section of Nutrition, Denver 80262, USA
    Am J Clin Nutr 79:1053-9. 2004
    ....
  29. ncbi request reprint Zinc homeostasis during lactation in a population with a low zinc intake
    Lei Sian
    Section of Nutrition, The Department of Pediatrics, The University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Clin Nutr 75:99-103. 2002
    ....
  30. pmc Absorption of calcium from tortilla meals prepared from low-phytate maize
    K Michael Hambidge
    Department of Pediatrics, Section of Nutrition, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Clin Nutr 82:84-7. 2005
    ..Bioavailability of calcium is, however, compromised by phytate, which is present in large quantities in maize kernels and is only modestly reduced by nixtamalization...
  31. ncbi request reprint Major variables of zinc homeostasis in Chinese toddlers
    Xiao Yang Sheng
    Department of Child and Adolescent Health, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Am J Clin Nutr 84:389-94. 2006
    ..The data required for this approach have not been available for toddlers, whose requirements have been estimated by extrapolation from other age groups...
  32. ncbi request reprint Community-based dietary phytate reduction and its effect on iron status in Malawian children
    Mark J Manary
    Department of Pediatrics, Washington University School of Medicine, St Louis Children s Hospital, One Children s Place, St Louis, MO 63110, USA
    Ann Trop Paediatr 22:133-6. 2002
    ..Phytate was removed by soaking maize flour in excess water with phytase and decanting the water before cooking the flour. Iron status, as measured by soluble transferrin receptor and zinc protoporphyrin, was improved but not normal...
  33. ncbi request reprint Validation of a food frequency questionnaire in preschool children
    Lezlie A Parrish
    Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver 80262, USA
    Epidemiology 14:213-7. 2003
    ..Support for the validity of food frequency questionnaires (FFQ) in preschool children using parental report is limited...
  34. pmc The use of dysprosium to measure endogenous zinc excretion in feces eliminates the necessity of complete fecal collections
    Leland V Miller
    University of Colorado Denver, Department of Pediatrics, Aurora, CO 80045, USA
    J Nutr 140:1524-8. 2010
    ..We found that the measurement of the sample Dy:Zn ratio was useful for selecting samples for measurement. We conclude that the Dy method of determining EFZ is a valid and less burdensome alternative to current techniques...
  35. pmc Efficacy and safety of a high protein, low carbohydrate diet for weight loss in severely obese adolescents
    Nancy F Krebs
    Department of Pediatrics, Section of Nutrition, University of Colorado Denver, Aurora, CO 80045, USA
    J Pediatr 157:252-8. 2010
    ..To evaluate the efficacy and safety of a carbohydrate restricted versus a low fat diet on weight loss, metabolic markers, body composition, and cardiac function tests in severely obese adolescents...
  36. pmc Early growth faltering in healthy term infants predicts longitudinal growth
    Erin S Ross
    Section of Nutrition, Department of Pediatrics, School of Medicine, University of Colorado Denver, Aurora, CO 80045, USA
    Early Hum Dev 85:583-8. 2009
    ..Early growth monitoring may not identify infants at-risk for later growth faltering because it is difficult for the provider to recognize how large of a negative shift might be problematic...
  37. ncbi request reprint Disease severity at time of referral for pediatric failure to thrive and obesity: time for a paradigm shift?
    Laurie A Miller
    Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Denver 80262, USA
    J Pediatr 141:121-4. 2002
    ..Results indicated that underweight children were mildly underweight, whereas the overweight children were severely so. In primary care settings, underweight children may be referred more aggressively than overweight children...
  38. doi request reprint Breastfeeding and WIC enrollment in the Nurse Family Partnership Program
    Maya Bunik
    Department of Pediatrics, University of Colorado Denver, Aurora, Colorado, USA
    Breastfeed Med 4:145-9. 2009
    ..Our aim was to compare breastfeeding rates at 6 and 12 months in NFP high-risk mothers who were enrolled in WIC to those who were not enrolled in WIC...
  39. ncbi request reprint Zinc, low birth weight, and breastfeeding
    K Michael Hambidge
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Pediatrics 112:1419-20. 2003
  40. ncbi request reprint Accuracy of simple techniques for estimating fractional zinc absorption in humans
    Michael Hambidge
    J Nutr 132:322-3. 2002
  41. ncbi request reprint Zinc absorption and exchangeable zinc pool sizes in breast-fed infants fed meat or cereal as first complementary food
    Sanju Jalla
    Johns Hopkins University, Baltimore, Maryland, USA
    J Pediatr Gastroenterol Nutr 34:35-41. 2002
    ....
  42. ncbi request reprint Zinc absorption in Guatemalan schoolchildren fed normal or low-phytate maize
    Manolo Mazariegos
    Center for Studies of Sensory Impairments, Aging, and Metabolism, Guatemala City, Guatemala
    Am J Clin Nutr 83:59-64. 2006
    ..Poor bioavailability of zinc from high-phytate diets is an important contributory factor to zinc deficiency in low-income populations...
  43. ncbi request reprint Inadequate intakes of dietary zinc among pregnant women from subsistence households in Sidama, Southern Ethiopia
    Yewelsew Abebe
    College of Agriculture, Hawassa University, Awassa, Ethiopia
    Public Health Nutr 11:379-86. 2008
    ..To assess the prevalence of zinc inadequacy based on dietary intakes and plasma zinc concentrations and, simultaneously, the prevalence of inadequate intakes of energy, protein, calcium and iron...
  44. ncbi request reprint Lower calcium absorption in infants fed casein hydrolysate- and soy protein-based infant formulas containing palm olein versus formulas without palm olein
    Karin M Ostrom
    Research and Development and Scientific Affairs, Ross Products Division, Abbott Laboratories, Columbus, Ohio 43215, USA
    J Am Coll Nutr 21:564-9. 2002
    ..In both SPF and CHF virtually all calcium is added as calcium salts...
  45. ncbi request reprint Prevention of pediatric overweight and obesity
    Nancy F Krebs
    Pediatrics 112:424-30. 2003
    ..This statement proposes strategies for early identification of excessive weight gain by using body mass index, for dietary and physical activity interventions during health supervision encounters, and for advocacy and research...
  46. ncbi request reprint Longitudinal measurements of zinc absorption in Peruvian children consuming wheat products fortified with iron only or iron and 1 of 2 amounts of zinc
    Daniel Lopez de Romaña
    Program in International Nutrition and the Department of Nutrition, University of California, Davis 95616, USA
    Am J Clin Nutr 81:637-47. 2005
    ..Information is needed on the fractional absorption of zinc (FAZ) and absorbed zinc (AZ) during prolonged exposure to zinc-fortified foods...
  47. ncbi request reprint Zinc homeostasis in premature infants does not differ between those fed preterm formula or fortified human milk
    Sanju Jalla
    Johns Hopkins Oncology Center, Johns Hopkins University, Baltimore, Maryland 21231, USA
    Pediatr Res 56:615-20. 2004
    ..Current zinc intakes from fortified human milk or formula are associated with acceptable weight gain, but whether the observed net zinc absorption was optimal in the human milk group cannot be definitively determined from these data...
  48. ncbi request reprint Optimizing bone health and calcium intakes of infants, children, and adolescents
    Frank R Greer
    Pediatrics 117:578-85. 2006
    ..Establishing these practices in childhood is important so that they will be followed throughout the life span...
  49. pmc Zinc, gravida, infection, and iron, but not vitamin B-12 or folate status, predict hemoglobin during pregnancy in Southern Ethiopia
    Rosalind S Gibson
    Department of Human Nutrition, University of Otago, Dunedin, New Zealand 9015
    J Nutr 138:581-6. 2008
    ..Despite some early functional vitamin B-12 deficiency, there was no macrocytic anemia. Consumption of fermented enset may have increased vitamin B-12 levels in diet and plasma...
  50. ncbi request reprint Bariatric surgery for severely overweight adolescents: concerns and recommendations
    Thomas H Inge
    Department of Pediatric Surgery, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229, USA
    Pediatrics 114:217-23. 2004
    ..Surgery should be performed in institutions that are equipped to meet the tertiary care needs of severely obese patients and to collect long-term data on the clinical outcomes of these patients...
  51. ncbi request reprint Plasma zinc concentrations are depressed during the acute phase response in children with falciparum malaria
    Christopher Duggan
    Division of Gastroenterology and Nutrition, Children s Hospital, Boston, MA, USA
    J Nutr 135:802-7. 2005
    ..In children whose age, diet, and/or nutritional status place them at risk of zinc deficiency, those with low plasma zinc levels should be supplemented with oral zinc and followed for clinical and/or biochemical response...

Research Grants4

  1. Intestinal Endogenous Zinc: Role for Metallothionein?
    Nancy Krebs; Fiscal Year: 2003
    ..abstract_text> ..
  2. INTEGRATION OF CLINICAL NUTRITION INTO MEDICAL TRAINING
    Nancy Krebs; Fiscal Year: 2004
    ..An evaluation will examine process and impact on learner knowledge, attitudes, and confidence regarding nutrition assessment and counseling. ..
  3. INSTITUTIONAL TRAINING PROGRAM IN NUTRITION
    Nancy Krebs; Fiscal Year: 2007
    ....