Matthew D Krasowski

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. pmc Positive hepatitis B surface antigen tests due to recent vaccination: a persistent problem
    Carolyn D Rysgaard
    Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA
    BMC Clin Pathol 12:15. 2012
  2. pmc Clinical decision support of therapeutic drug monitoring of phenytoin: measured versus adjusted phenytoin plasma concentrations
    Matthew D Krasowski
    Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    BMC Med Inform Decis Mak 12:7. 2012
  3. pmc A retrospective analysis of glycol and toxic alcohol ingestion: utility of anion and osmolal gaps
    Matthew D Krasowski
    Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA
    BMC Clin Pathol 12:1. 2012
  4. pmc Evolutionary diversity of bile salts in reptiles and mammals, including analysis of ancient human and extinct giant ground sloth coprolites
    Lee R Hagey
    Department of Medicine, University of California San Diego, La Jolla, CA, USA
    BMC Evol Biol 10:133. 2010
  5. pmc The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species
    Matthew D Krasowski
    Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    BMC Biochem 12:5. 2011
  6. pmc Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR
    Matthew D Krasowski
    Department of Pathology, University of Iowa Hospitals and Clinics, RCP 6233, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Mol Cell Endocrinol 334:39-48. 2011
  7. pmc Evolution of the bile salt nuclear receptor FXR in vertebrates
    Erica J Reschly
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    J Lipid Res 49:1577-87. 2008
  8. pmc Drug monitoring: simultaneous analysis of lamotrigine, oxcarbazepine, 10-hydroxycarbazepine, and zonisamide by HPLC-UV and a rapid GC method using a nitrogen-phosphorus detector for levetiracetam
    Elizabeth Greiner-Sosanko
    Toxicology and Therapeutic Drug Monitoring Laboratory, Division of Clinical Chemistry, Department of Pathology, University of Pittsburgh Medical Center, Children s Hospital Main Tower 5812, Pittsburgh, PA 15213, USA
    J Chromatogr Sci 45:616-22. 2007
  9. pmc Functional evolution of the vitamin D and pregnane X receptors
    Erica J Reschly
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Evol Biol 7:222. 2007
  10. pmc Functional evolution of the pregnane X receptor
    Manisha Iyer
    Department of Pathology, University of Pittsburgh, Scaife Hall S 730, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    Expert Opin Drug Metab Toxicol 2:381-97. 2006

Collaborators

  • Sean Ekins
  • Anthony F Pizon
  • Gwendolyn A McMillin
  • Alan F Hofmann
  • Nathan Bahary
  • Erica J Reschly
  • Lee R Hagey
  • Elizabeth Greiner-Sosanko
  • Carolyn D Rysgaard
  • Denny Drees
  • Vilte E Barakauskas
  • Michelle Kurt-Mangold
  • Mohamed A Virji
  • Darla R Lower
  • E J Reschly
  • Manisha Iyer
  • Jeff Kulhavy
  • Tami Bebber
  • Cory S Morris
  • Rebecka Davis
  • Scott R Davis
  • Nicolas Vidal
  • William J Welsh
  • Ni Ai
  • Raman Venkataramanan
  • Jaco Joaquim Mattos
  • Afonso Celso Dias Bainy
  • Junhai Ou
  • Spiros Giannoutsos
  • Sripal R Mada

Detail Information

Publications20

  1. pmc Positive hepatitis B surface antigen tests due to recent vaccination: a persistent problem
    Carolyn D Rysgaard
    Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA
    BMC Clin Pathol 12:15. 2012
    ..abstract:..
  2. pmc Clinical decision support of therapeutic drug monitoring of phenytoin: measured versus adjusted phenytoin plasma concentrations
    Matthew D Krasowski
    Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    BMC Med Inform Decis Mak 12:7. 2012
    ..The measured free phenytoin plasma concentration was used as the gold standard...
  3. pmc A retrospective analysis of glycol and toxic alcohol ingestion: utility of anion and osmolal gaps
    Matthew D Krasowski
    Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA
    BMC Clin Pathol 12:1. 2012
    ..abstract:..
  4. pmc Evolutionary diversity of bile salts in reptiles and mammals, including analysis of ancient human and extinct giant ground sloth coprolites
    Lee R Hagey
    Department of Medicine, University of California San Diego, La Jolla, CA, USA
    BMC Evol Biol 10:133. 2010
    ..We greatly extend prior surveys of bile salt diversity in both reptiles and mammals, including analysis of 8,000 year old human coprolites and coprolites from the extinct Shasta ground sloth (Nothrotherium shastense)...
  5. pmc The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species
    Matthew D Krasowski
    Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    BMC Biochem 12:5. 2011
    ..We utilize homology modelling, docking, and pharmacophore studies to understand the structural features of the Tetraodon receptors...
  6. pmc Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR
    Matthew D Krasowski
    Department of Pathology, University of Iowa Hospitals and Clinics, RCP 6233, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Mol Cell Endocrinol 334:39-48. 2011
    ....
  7. pmc Evolution of the bile salt nuclear receptor FXR in vertebrates
    Erica J Reschly
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    J Lipid Res 49:1577-87. 2008
    ..Our observations present an integrated picture of the coevolution of bile salt structure and of the binding pocket of their target nuclear receptor FXR...
  8. pmc Drug monitoring: simultaneous analysis of lamotrigine, oxcarbazepine, 10-hydroxycarbazepine, and zonisamide by HPLC-UV and a rapid GC method using a nitrogen-phosphorus detector for levetiracetam
    Elizabeth Greiner-Sosanko
    Toxicology and Therapeutic Drug Monitoring Laboratory, Division of Clinical Chemistry, Department of Pathology, University of Pittsburgh Medical Center, Children s Hospital Main Tower 5812, Pittsburgh, PA 15213, USA
    J Chromatogr Sci 45:616-22. 2007
    ....
  9. pmc Functional evolution of the vitamin D and pregnane X receptors
    Erica J Reschly
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Evol Biol 7:222. 2007
    ..In addition, several assays were used to search for evidence of PXR-mediated hepatic effects in three model non-mammalian species: sea lamprey (Petromyzon marinus), zebrafish (Danio rerio), and African clawed frog (Xenopus laevis)...
  10. pmc Functional evolution of the pregnane X receptor
    Manisha Iyer
    Department of Pathology, University of Pittsburgh, Scaife Hall S 730, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    Expert Opin Drug Metab Toxicol 2:381-97. 2006
    ..Research into the evolutionary history of the PXR gene has also provided insight into the function of PXR in humans and other animals...
  11. pmc Molecular similarity methods for predicting cross-reactivity with therapeutic drug monitoring immunoassays
    Matthew D Krasowski
    Department of Pathology, University of Pittsburgh, Scaife Hall S 737, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    Ther Drug Monit 31:337-44. 2009
    ....
  12. pmc Chemoinformatic methods for predicting interference in drug of abuse/toxicology immunoassays
    Matthew D Krasowski
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Clin Chem 55:1203-13. 2009
    ..To date, there has been little systematic investigation using computational tools to predict cross-reactive compounds...
  13. pmc Evolution of the pregnane x receptor: adaptation to cross-species differences in biliary bile salts
    Matthew D Krasowski
    University of Pittsburgh, Department of Pathology, 200 Lothrop, Pittsburgh, PA 15213, USA
    Mol Endocrinol 19:1720-39. 2005
    ..PXR specificity for bile salts has thus paralleled the increasing complexity of the bile salt synthetic pathway during vertebrate evolution, an unusual example of ligand-receptor coevolution in the nuclear hormone receptor superfamily...
  14. pmc Intrinsic disorder in nuclear hormone receptors
    Matthew D Krasowski
    Department of Pathology, University of Pittsburgh, Scaife Hall S 737, 3550 Terrace Street Pittsburgh, Pennsylvania 15261, USA
    J Proteome Res 7:4359-72. 2008
    ..This information enables further understanding of these therapeutic targets...
  15. pmc Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds
    E J Reschly
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Curr Drug Metab 7:349-65. 2006
    ..This review examines the insights that phylogenetic and experimental studies provide into the function of VDR, PXR, and CAR, and how the functions of these receptors have expanded to evolutionary advantage in humans and other animals...
  16. pmc Using molecular similarity to highlight the challenges of routine immunoassay-based drug of abuse/toxicology screening in emergency medicine
    Matthew D Krasowski
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Emerg Med 9:5. 2009
    ..For immunoassays targeted at a particular class of drugs, there can also be false negatives if there is failure to detect some drugs or their metabolites within that class...
  17. doi request reprint Extremely high myoglobin plasma concentrations producing hook effect in a critically ill patient
    Michelle Kurt-Mangold
    Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    Clin Chim Acta 414:179-81. 2012
    ..The patient required extended cardiopulmonary resuscitation and had further complications including compartment syndrome...
  18. doi request reprint Unresolved discrepancies between cannabinoid test results for infant urine
    Vilte E Barakauskas
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA
    Clin Chem 58:1364-7. 2012
    ..This study investigated the rate of unconfirmed positive screen results in infant and noninfant urine samples and evaluated possible reasons for differences...
  19. pmc Simultaneous determination of lamotrigine, zonisamide, and carbamazepine in human plasma by high-performance liquid chromatography
    Elizabeth Greiner-Sosanko
    Toxicology and Therapeutic Drug Monitoring Laboratory, Division of Clinical Chemistry, Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Biomed Chromatogr 21:225-8. 2007
    ..Other anti-epileptic medications tested did not interfere with the assay. The method is appropriate for determining lamotrigine, carbamazepine and zonisamide serum or plasma concentrations for therapeutic monitoring...
  20. doi request reprint Pathology consultation on vitamin D testing
    Matthew D Krasowski
    Department of Pathology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Am J Clin Pathol 136:507-14. 2011
    ..This article presents a common clinical case scenario regarding vitamin D and an up-to-date discussion and review of the literature on vitamin D testing...