Randall H Kramer

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Tumor cell invasion and survival in head and neck cancer
    Randall H Kramer
    Head and Neck Oncology Program, Department of Cell and Tissue Biology, University of California San Francisco, San Francisco, CA 94143, USA
    Cancer Metastasis Rev 24:35-45. 2005
  2. doi request reprint Bcl-2 overexpression induces a partial epithelial to mesenchymal transition and promotes squamous carcinoma cell invasion and metastasis
    Jianhong Zuo
    Department of Cell and Tissue Biology, University of California San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0640, USA
    Mol Cancer Res 8:170-82. 2010
  3. pmc Analysis of human muscle stem cells reveals a differentiation-resistant progenitor cell population expressing Pax7 capable of self-renewal
    Bradley Pawlikowski
    Department of Cell and Tissue Biology, University of California San Francisco, School of Dentistry, San Francisco, California 94143, USA
    Dev Dyn 238:138-49. 2009
  4. ncbi request reprint Integrin engagement differentially modulates epithelial cell motility by RhoA/ROCK and PAK1
    Hua Zhou
    Department of Cell and Tissue Biology, University of California, San Francisco, California 94143, USA
    J Biol Chem 280:10624-35. 2005
  5. pmc Sdc1 negatively modulates carcinoma cell motility and invasion
    Tohru Ishikawa
    Department of Cell and Tissue Biology, University of California San Francisco, 521 Parnassus Avenue, Room C 640, San Francisco, CA 94143 0640, USA
    Exp Cell Res 316:951-65. 2010
  6. pmc STAT3 signaling is induced by intercellular adhesion in squamous cell carcinoma cells
    Akiko Onishi
    Department of Cell and Tissue Biology, University of California San Francisco, San Francisco, California 94143 0640, USA
    Exp Cell Res 314:377-86. 2008
  7. pmc Modulation of satellite cell adhesion and motility following BMP2-induced differentiation to osteoblast lineage
    Nobuaki Ozeki
    Department of Cell and Tissue Biology, University of California at San Francisco, San Francisco, CA 94143, USA
    Biochem Biophys Res Commun 353:54-9. 2007
  8. doi request reprint Transcriptional profiling identifies upregulated genes following induction of epithelial-mesenchymal transition in squamous carcinoma cells
    Joseph O Humtsoe
    Department of Cell and Tissue Biology, School of Dentistry, 521 Parnassus Avenue, University of California at San Francisco, San Francisco, CA 94143, USA
    Exp Cell Res 318:379-90. 2012
  9. pmc alpha7 integrin expressing human fetal myogenic progenitors have stem cell-like properties and are capable of osteogenic differentiation
    Nobuaki Ozeki
    Department of Cell and Tissue Biology, University of California San Francisco, Box 0640, 521 Parnassus Avenue, Room C 640, San Francisco, CA 94143 0640, USA
    Exp Cell Res 312:4162-80. 2006
  10. ncbi request reprint Alpha7 integrin expression is negatively regulated by deltaEF1 during skeletal myogenesis
    Poonam Jethanandani
    Department of Cell and Tissue Biology, University of California, San Francisco, California 94143 0640, USA
    J Biol Chem 280:36037-46. 2005

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Tumor cell invasion and survival in head and neck cancer
    Randall H Kramer
    Head and Neck Oncology Program, Department of Cell and Tissue Biology, University of California San Francisco, San Francisco, CA 94143, USA
    Cancer Metastasis Rev 24:35-45. 2005
    ..Understanding the molecular events that define this subset of invasive cells will facilitate the development of new treatment strategies...
  2. doi request reprint Bcl-2 overexpression induces a partial epithelial to mesenchymal transition and promotes squamous carcinoma cell invasion and metastasis
    Jianhong Zuo
    Department of Cell and Tissue Biology, University of California San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0640, USA
    Mol Cancer Res 8:170-82. 2010
    ....
  3. pmc Analysis of human muscle stem cells reveals a differentiation-resistant progenitor cell population expressing Pax7 capable of self-renewal
    Bradley Pawlikowski
    Department of Cell and Tissue Biology, University of California San Francisco, School of Dentistry, San Francisco, California 94143, USA
    Dev Dyn 238:138-49. 2009
    ..This study extends our understanding of the role of Pax7 in regulating human satellite stem cell differentiation and self-renewal...
  4. ncbi request reprint Integrin engagement differentially modulates epithelial cell motility by RhoA/ROCK and PAK1
    Hua Zhou
    Department of Cell and Tissue Biology, University of California, San Francisco, California 94143, USA
    J Biol Chem 280:10624-35. 2005
    ..The data demonstrate that specific ligand-integrin pairs regulate cell motility differentially by selectively modulating activities of Rho GTPases and their effectors...
  5. pmc Sdc1 negatively modulates carcinoma cell motility and invasion
    Tohru Ishikawa
    Department of Cell and Tissue Biology, University of California San Francisco, 521 Parnassus Avenue, Room C 640, San Francisco, CA 94143 0640, USA
    Exp Cell Res 316:951-65. 2010
    ..Downregulation of Sdc1 expression during carcinoma progression may represent a mechanism by which tumor cells become more invasive and metastatic...
  6. pmc STAT3 signaling is induced by intercellular adhesion in squamous cell carcinoma cells
    Akiko Onishi
    Department of Cell and Tissue Biology, University of California San Francisco, San Francisco, California 94143 0640, USA
    Exp Cell Res 314:377-86. 2008
    ..These results indicate that, in HNSCC cells, cadherin-mediated intercellular adhesion induces STAT signaling that may modulate cell survival and resistance to apoptosis during tumor progression...
  7. pmc Modulation of satellite cell adhesion and motility following BMP2-induced differentiation to osteoblast lineage
    Nobuaki Ozeki
    Department of Cell and Tissue Biology, University of California at San Francisco, San Francisco, CA 94143, USA
    Biochem Biophys Res Commun 353:54-9. 2007
    ..The results identify a novel role for BMP2 in modulating satellite cell integrin expression and altering their interactions with the microenvironment during osteoblastic differentiation...
  8. doi request reprint Transcriptional profiling identifies upregulated genes following induction of epithelial-mesenchymal transition in squamous carcinoma cells
    Joseph O Humtsoe
    Department of Cell and Tissue Biology, School of Dentistry, 521 Parnassus Avenue, University of California at San Francisco, San Francisco, CA 94143, USA
    Exp Cell Res 318:379-90. 2012
    ..This set of newly identified genes that are modulated during EMT-like conversion may be important diagnostic biomarkers during the process of HNSCC progression...
  9. pmc alpha7 integrin expressing human fetal myogenic progenitors have stem cell-like properties and are capable of osteogenic differentiation
    Nobuaki Ozeki
    Department of Cell and Tissue Biology, University of California San Francisco, Box 0640, 521 Parnassus Avenue, Room C 640, San Francisco, CA 94143 0640, USA
    Exp Cell Res 312:4162-80. 2006
    ....
  10. ncbi request reprint Alpha7 integrin expression is negatively regulated by deltaEF1 during skeletal myogenesis
    Poonam Jethanandani
    Department of Cell and Tissue Biology, University of California, San Francisco, California 94143 0640, USA
    J Biol Chem 280:36037-46. 2005
    ..These findings suggest that deltaEF1 has a role in suppressing integrin expression in myoblasts by displacing MYOD and competing for p300/CBP co-activator...
  11. ncbi request reprint Regulation of alpha7 integrin expression during muscle differentiation
    Jianqiao Xiao
    Departments of Stomatology and Anatomy, University of California at San Francisco, San Francisco, California 94143 0422, USA
    J Biol Chem 278:49780-8. 2003
    ..Our results suggest that the interaction of c-Myc with this promoter region is an important regulatory element controlling alpha7 integrin expression during muscle development and myotendinous junction formation...
  12. pmc The beta1 cytoplasmic domain regulates the laminin-binding specificity of the alpha7X1 integrin
    Ming Guang Yeh
    Department of Stomatology, University of California at San Francisco, San Francisco, CA 94143 0512, USA
    Mol Biol Cell 14:3507-18. 2003
    ..Functional regulation of alpha7beta1 by developmentally regulated splicing events may be important during myogenic differentiation and repair because the integrin mediates adhesion, motility, and cell survival...
  13. pmc Adhesion-mediated squamous cell carcinoma survival through ligand-independent activation of epidermal growth factor receptor
    Xiaodong Shen
    Department of Stomatology, School of Medicine, University of California at San Francisco, Box 0512, Room HSW 604, San Francisco, CA 94143 0512, USA
    Am J Pathol 165:1315-29. 2004
    ..Our data implicate cell-cell adhesion-induced activation of EGFR as a cooperative mechanism that generates compensatory survival signaling, protecting malignant cells from detachment-induced death...
  14. ncbi request reprint The extracellular matrix protein betaIG-H3 is expressed at myotendinous junctions and supports muscle cell adhesion
    Jill W Ferguson
    Department of Biology, The University of Texas at San Antonio, 6900 North Loop 1604 West, TX 78249, San Antonio, USA
    Cell Tissue Res 313:93-105. 2003
    ....
  15. ncbi request reprint Dominant-negative E-cadherin alters adhesion and reverses contact inhibition of growth in breast carcinoma cells
    Ioannis S Vizirianakis
    Laboratory of Pharmacology, Department of Pharmaceutical Sciences, Aristotle University of Thessaloniki, GR 54006 Thessaloniki, Greece
    Int J Oncol 21:135-44. 2002
    ..Overall, these observations suggest that in breast carcinoma, disruption of E-cadherin and catenin function modulates both cell-cell adhesion and permits escape from cell-cell contact-involved inhibition of cell growth...