Joel H Kramer

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Configural errors on WISC-III block design
    J H Kramer
    University of California, San Francisco Medical Center, USA
    J Int Neuropsychol Soc 5:518-24. 1999
  2. ncbi Developmental sex differences in verbal learning
    J H Kramer
    Department of Psychiatry, University of California, Medical Center, San Francisco 94143, USA
    Neuropsychology 11:577-84. 1997
  3. pmc Forgetting in dementia with and without subcortical lacunes
    Joel H Kramer
    San Francisco Medical Center, University of California, CA 94143, USA
    Clin Neuropsychol 18:32-40. 2004
  4. ncbi The role of perceptual bias in complex figure recall
    Joel H Kramer
    San Francisco Medical Center, University of California, San Francisco, CA 94143, USA
    J Clin Exp Neuropsychol 26:838-45. 2004
  5. pmc Hippocampal volume and retention in Alzheimer's disease
    Joel H Kramer
    Department of Neurology, University of California at San Francisco, 94143, USA
    J Int Neuropsychol Soc 10:639-43. 2004
  6. ncbi Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer disease
    Joel H Kramer
    University of California Medical Center, San Francisco, California 94143, USA
    Cogn Behav Neurol 16:211-8. 2003
  7. pmc Multiple cognitive deficits in amnestic mild cognitive impairment
    Joel H Kramer
    San Francisco Medical Center, University of California, San Francisco, CA 94143, USA
    Dement Geriatr Cogn Disord 22:306-11. 2006
  8. ncbi Age and gender interactions on verbal memory performance
    Joel H Kramer
    University of California, San Francisco Medical Center, 94143, USA
    J Int Neuropsychol Soc 9:97-102. 2003
  9. pmc Dissociations in hippocampal and frontal contributions to episodic memory performance
    Joel H Kramer
    Department of Neurology, University of California, San Francisco Medical Center, San Francisco, CA 94143, USA
    Neuropsychology 19:799-805. 2005
  10. pmc Executive dysfunction in subcortical ischaemic vascular disease
    J H Kramer
    San Francisco Medical Center, University of California, 401 Parnassus Avenue, San Francisco, CA 94143, USA
    J Neurol Neurosurg Psychiatry 72:217-20. 2002

Detail Information

Publications132 found, 100 shown here

  1. ncbi Configural errors on WISC-III block design
    J H Kramer
    University of California, San Francisco Medical Center, USA
    J Int Neuropsychol Soc 5:518-24. 1999
    ..Broken configurations are also made more frequently by children whose perception is less influenced by the global properties of spatial stimuli...
  2. ncbi Developmental sex differences in verbal learning
    J H Kramer
    Department of Psychiatry, University of California, Medical Center, San Francisco 94143, USA
    Neuropsychology 11:577-84. 1997
    ..Because boys had higher mean scores on Wechsler Intelligence Scale for Children--Revised Vocabulary, the observed female superiority in verbal learning could not be attributed to sex differences in overall word knowledge...
  3. pmc Forgetting in dementia with and without subcortical lacunes
    Joel H Kramer
    San Francisco Medical Center, University of California, CA 94143, USA
    Clin Neuropsychol 18:32-40. 2004
    ..Three SIVD patients with rapid forgetting followed to autopsy all had AD pathology, further supporting the link between memory patterns and AD...
  4. ncbi The role of perceptual bias in complex figure recall
    Joel H Kramer
    San Francisco Medical Center, University of California, San Francisco, CA 94143, USA
    J Clin Exp Neuropsychol 26:838-45. 2004
    ....
  5. pmc Hippocampal volume and retention in Alzheimer's disease
    Joel H Kramer
    Department of Neurology, University of California at San Francisco, 94143, USA
    J Int Neuropsychol Soc 10:639-43. 2004
    ..Results suggest that the role of the hippocampus is relatively specific to the consolidation of new memories...
  6. ncbi Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer disease
    Joel H Kramer
    University of California Medical Center, San Francisco, California 94143, USA
    Cogn Behav Neurol 16:211-8. 2003
    ..To assess the ability of a brief neuropsychological bedside screening battery to discriminate between Alzheimer disease, frontotemporal dementia, and semantic dementia...
  7. pmc Multiple cognitive deficits in amnestic mild cognitive impairment
    Joel H Kramer
    San Francisco Medical Center, University of California, San Francisco, CA 94143, USA
    Dement Geriatr Cogn Disord 22:306-11. 2006
    ..To determine if more widespread cognitive deficits are present in a narrowly defined group of patients with the amnestic form of mild cognitive impairment (MCI)...
  8. ncbi Age and gender interactions on verbal memory performance
    Joel H Kramer
    University of California, San Francisco Medical Center, 94143, USA
    J Int Neuropsychol Soc 9:97-102. 2003
    ..The role of estrogen on cognition in normal aging warrants further study...
  9. pmc Dissociations in hippocampal and frontal contributions to episodic memory performance
    Joel H Kramer
    Department of Neurology, University of California, San Francisco Medical Center, San Francisco, CA 94143, USA
    Neuropsychology 19:799-805. 2005
    ....
  10. pmc Executive dysfunction in subcortical ischaemic vascular disease
    J H Kramer
    San Francisco Medical Center, University of California, 401 Parnassus Avenue, San Francisco, CA 94143, USA
    J Neurol Neurosurg Psychiatry 72:217-20. 2002
    ..Executive dysfunction has been reported in patients with subcortical-frontal pathology, even in the absence of dementia...
  11. pmc Neuropathological basis of magnetic resonance images in aging and dementia
    William J Jagust
    School of Public Health and Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720 3190, USA
    Ann Neurol 63:72-80. 2008
    ..Magnetic resonance (MR) imaging is used widely for assessment of patients with cognitive impairment, but the pathological correlates are unclear, especially when multiple pathologies are present...
  12. pmc Influences of lobar gray matter and white matter lesion load on cognition and mood
    Susanne G Mueller
    Center for Imaging of Neurodegenerative Diseases, VAMC University of California San Francisco, 4150 Clement Street, San Francisco, CA, 94121, USA
    Psychiatry Res 181:90-6. 2010
    ..Cognitive function is associated with GM atrophy and depressed mood is associated with frontal WML. This indicates that although both often occur together, depressed mood and cognitive impairment have different pathological correlates...
  13. pmc Cerebral blood flow in ischemic vascular dementia and Alzheimer's disease, measured by arterial spin-labeling magnetic resonance imaging
    Norbert Schuff
    Department of Veterans Affairs Medical Center, University of California at San Francisco, USA
    Alzheimers Dement 5:454-62. 2009
    ....
  14. pmc Neuropsychological correlates of dominance, warmth, and extraversion in neurodegenerative disease
    Marc Sollberger
    Memory and Aging Center, UCSF Department of Neurology, University of California San Francisco, 350 Parnassus Avenue, San Francisco, CA 94143 1207, USA
    Cortex 48:674-82. 2012
    ..In this study, we hypothesized that different combinations of cognitive, neuropsychiatric, and emotional measures would predict different interpersonal traits in patients with neurodegenerative diseases...
  15. ncbi Profiles of neuropsychological impairment in autopsy-defined Alzheimer's disease and cerebrovascular disease
    Bruce R Reed
    University of California, Davis, CA, USA
    Brain 130:731-9. 2007
    ....
  16. pmc Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia
    An Tao Du
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Brain 130:1159-66. 2007
    ..In conclusion, the characteristic patterns of cortical thinning in Alzheimer's disease and FTD suggest that cortical thickness may be a useful surrogate marker for these types of dementia...
  17. ncbi Neuroanatomical correlates of impaired recognition of emotion in dementia
    Howard J Rosen
    University of California at San Francisco Department of Neurology, Memory and Aging Center, 350 Parnassus Avenue, Suite 706, Box 1207, San Francisco, CA 94143 1207, USA
    Neuropsychologia 44:365-73. 2006
    ....
  18. pmc The MRI brain correlates of depressed mood, anhedonia, apathy, and anergia in older adults with and without cognitive impairment or dementia
    Helen Lavretsky
    Department of Psychiatry, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Int J Geriatr Psychiatry 23:1040-50. 2008
    ..We examined the magnetic resonance imaging (MRI) correlates of depressed mood, apathy, anhedonia, and anergia in older adults with and without cognitive impairment or dementia...
  19. pmc Longitudinal MRI and cognitive change in healthy elderly
    Joel H Kramer
    Department of Neurology, San Francisco Medical Center, University of California, San Francisco, CA 94143, USA
    Neuropsychology 21:412-8. 2007
    ..The association between WMSH and EXEC further highlights the cognitive sequealae associated with cerebrovascular disease in normal elderly...
  20. pmc Rule violation errors are associated with right lateral prefrontal cortex atrophy in neurodegenerative disease
    Katherine L Possin
    Department of Neurology, University of California San Francisco, San Francisco, California, USA
    J Int Neuropsychol Soc 15:354-64. 2009
    ..These data underscore the importance of right lateral PFC in behavioral monitoring and highlight the potential of RV error assessment for identifying patients with damage to this region...
  21. pmc Frontal paralimbic network atrophy in very mild behavioral variant frontotemporal dementia
    William W Seeley
    UCSF Memory and Aging Center, University of California San Francisco, 350 Parnassus Avenue, San Francisco, CA 94143 1207, USA
    Arch Neurol 65:249-55. 2008
    ..Behavioral variant frontotemporal dementia (bvFTD) strikes hardest at the frontal lobes, but the sites of earliest injury remain unclear...
  22. pmc Effects of Alzheimer disease on fronto-parietal brain N-acetyl aspartate and myo-inositol using magnetic resonance spectroscopic imaging
    Xiaoping Zhu
    Department of Radiology, VA Medical Center, University of California, San Francisco, CA 94121, USA
    Alzheimer Dis Assoc Disord 20:77-85. 2006
    ..However, the NAA and mI changes are not correlated with each other, suggesting that they represent different processes that might help staging of AD...
  23. pmc Association of depressed mood and mortality in older adults with and without cognitive impairment in a prospective naturalistic study
    Helen Lavretsky
    Department of Psychiatry, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Am J Psychiatry 167:589-97. 2010
    ....
  24. pmc Age effects on atrophy rates of entorhinal cortex and hippocampus
    An Tao Du
    Magnetic Resonance Unit 114M, Department of Veterans Affairs Medical Center, 4150, Clement Street, San Francisco, CA 94121, USA
    Neurobiol Aging 27:733-40. 2006
    ..In conclusion, age and presence of lacunes should be taken into consideration in imaging studies of CN subjects and AD patients to predict AD progression and assess the response to treatment trials...
  25. pmc Subcortical lacunes are associated with executive dysfunction in cognitively normal elderly
    Catherine L Carey
    Department of Psychiatry, University of California, San Diego, 150 W Washington, 2nd Floor San Diego, CA 92103, USA
    Stroke 39:397-402. 2008
    ..We therefore hypothesized that MRI markers of SIVD would be selectively associated with worse executive functioning...
  26. pmc Cognitive impact of subcortical vascular and Alzheimer's disease pathology
    Helena C Chui
    Department of Neurology, University of Southern California, Los Angeles, USA
    Ann Neurol 60:677-87. 2006
    ..To assess the interactions among three types of pathology (ie, cerebrovascular disease, hippocampal sclerosis [HS], and Alzheimer's disease [AD]), cognitive status, and apolipoprotein E genotype...
  27. pmc Baseline predictors of clinical progression among patients with dysexecutive mild cognitive impairment
    Julene K Johnson
    Institute for Health and Aging, University of California, San Francisco, USA
    Dement Geriatr Cogn Disord 30:344-51. 2010
    ..The purpose of this study was to evaluate baseline predictors of clinical progression after 2 years for patients with dysexecutive MCI (dMCI), a single-domain non-amnestic MCI subgroup...
  28. pmc Antisaccade task reflects cortical involvement in mild cognitive impairment
    Hilary W Heuer
    From the Memory and Aging Center H W H, J B M, E L K, B L M, J H K, A L B, Department of Neurology, University of California, San Francisco and Frontotemporal Disorders Unit B C D, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston
    Neurology 81:1235-43. 2013
    ....
  29. ncbi White matter lesions are associated with cortical atrophy more than entorhinal and hippocampal atrophy
    An Tao Du
    Magnetic Resonance Unit 114M, Department of Veterans Affairs Medical Center, 4150, Clement Street, San Francisco, CA 94121, USA
    Neurobiol Aging 26:553-9. 2005
    ..Further, AD pathology and subcortical vascular disease may independently affect cortical atrophy...
  30. pmc The frontal-anatomic specificity of design fluency repetitions and their diagnostic relevance for behavioral variant frontotemporal dementia
    Katherine L Possin
    Department of Neurology, University of California, San Francisco, San Francisco, California 94143 1207, USA
    J Int Neuropsychol Soc 18:834-44. 2012
    ..These results highlight the frontal-anatomic specificity of design fluency repetitions. In addition, the results indicate that the propensity to make these errors supports the diagnosis of bvFTD. (JINS, 2012, 18, 1-11)...
  31. pmc Double dissociation in the anatomy of socioemotional disinhibition and executive functioning in dementia
    Casey E Krueger
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, USA
    Neuropsychology 25:249-59. 2011
    ....
  32. pmc Development of methodology for conducting clinical trials in frontotemporal lobar degeneration
    David S Knopman
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Brain 131:2957-68. 2008
    ..There are several candidate outcome measures -- including the FTLD-CDR and the cognitive composites -- that could be used in clinical trials across the spectrum of FTLD...
  33. pmc TDP-43 frontotemporal lobar degeneration and autoimmune disease
    Zachary A Miller
    UCSF Memory and Aging Center, University of California San Francisco, San Francisco, California 94143 1207, USA
    J Neurol Neurosurg Psychiatry 84:956-62. 2013
    ..Given the association between systemic inflammation and other neurodegenerative processes, links between autoimmunity and FTD need to be explored...
  34. pmc Anterior temporal lobe degeneration produces widespread network-driven dysfunction
    Christine C Guo
    1 Memory and Ageing Centre, Department of Neurology, University of California, San Francisco, USA
    Brain 136:2979-91. 2013
    ..The findings provide a neurophysiological basis for the theory that semantic processing is orchestrated through interactions between a critical anterior temporal lobe hub and modality-selective processing nodes. ..
  35. doi Normative data in women aged 85 and older: verbal fluency, digit span, and the CVLT-II short form
    Eric M Fine
    Department of Neurology, University of California, San Francisco, CA, USA
    Clin Neuropsychol 26:18-30. 2012
    ..Findings from the present normative study are discussed within the context of "robust" longitudinal normative data...
  36. pmc Predicting regional neurodegeneration from the healthy brain functional connectome
    Juan Zhou
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA
    Neuron 73:1216-27. 2012
    ..Molecular pathological approaches may help clarify what makes each epicenter vulnerable to its targeting disease and how toxic protein species travel between networked brain structures...
  37. pmc C-reactive protein is related to memory and medial temporal brain volume in older adults
    Brianne Magouirk Bettcher
    Department of Neurology, University of California, San Francisco, Memory and Aging Center, San Francisco, CA, USA
    Brain Behav Immun 26:103-8. 2012
    ..These findings underscore a potential role for inflammation in cognitive aging as a modifiable risk factor...
  38. pmc Magnetic resonance imaging correlates of set shifting
    Joel H Kramer
    Department of Neurology, University of California San Francisco, San Francisco, CA 94143, USA
    J Int Neuropsychol Soc 13:386-92. 2007
    ..Follow-up analyses indicated that frontal contributions to shifting were not related to working memory. Results highlight the importance of carefully controlling for component cognitive processes when studying executive functioning...
  39. ncbi Discriminant validity and neuroanatomical correlates of rule monitoring in frontotemporal dementia and Alzheimer's disease
    Catherine L Carey
    Department of Psychiatry, University of California, San Francisco Medical Center, United States
    Neuropsychologia 46:1081-7. 2008
    ..Findings are consistent with literature implicating the frontal lobes in performance monitoring and highlight the importance of characterizing the component processes of performance failures in the cognitive assessment of FTD and AD...
  40. pmc Atrophy in two attention networks is associated with performance on a Flanker task in neurodegenerative disease
    Tracy L Luks
    Department of Radiology and Biomedical Imaging, University of California San Francisco, CA 94143, USA
    Neuropsychologia 48:165-70. 2010
    ....
  41. pmc White matter damage in frontotemporal dementia and Alzheimer's disease measured by diffusion MRI
    Yu Zhang
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Brain 132:2579-92. 2009
    ..Taken together, the results suggest that white matter degradation measured with DTI may improve the diagnostic differentiation between FTD and Alzheimer's disease...
  42. pmc Longitudinal changes in memory and executive functioning are associated with longitudinal change in instrumental activities of daily living in older adults
    Sarah Tomaszewski Farias
    Department of Neurology, School of Medicine, University of California, Davis, CA, USA
    Clin Neuropsychol 23:446-61. 2009
    ..Findings indicate that declines in MEM and EXEC over time make unique and independent contributions to declines in older adults' ability to function in daily life...
  43. pmc Gray matter correlates of set-shifting among neurodegenerative disease, mild cognitive impairment, and healthy older adults
    Judy Pa
    Alzheimer Disease Research Center, Dept of Neurology, University of California, San Francisco, California, USA
    J Int Neuropsychol Soc 16:640-50. 2010
    ..Overall, these findings highlight the neuroanatomical correlates of set-shifting and the importance of controlling for component processes when investigating complex cognitive tasks...
  44. pmc Intrinsic connectivity network disruption in progressive supranuclear palsy
    Raquel C Gardner
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA
    Ann Neurol 73:603-16. 2013
    ..Progressive supranuclear palsy (PSP) has been conceptualized as a large-scale network disruption, but the specific network targeted has not been fully characterized. We sought to delineate the affected network in patients with clinical PSP...
  45. pmc Executive functions and the down-regulation and up-regulation of emotion
    Anett Gyurak
    Departments of Psychiatry and Psychology, Stanford University, San Francisco, CA, USA
    Cogn Emot 26:103-18. 2012
    ..These findings contribute to our understanding of emotion-cognition interaction, suggesting a link between emotion-regulatory abilities and individual differences in complex executive functions...
  46. pmc Coronary artery disease is associated with cognitive decline independent of changes on magnetic resonance imaging in cognitively normal elderly adults
    Ling Zheng
    Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Am Geriatr Soc 60:499-504. 2012
    ..To examine in cognitively normal elderly adults whether vascular factors predict cognitive decline and whether these associations are mediated by magnetic resonance imaging (MRI) measures of subclinical vascular brain injury...
  47. pmc Patterns of white matter atrophy in frontotemporal lobar degeneration
    Linda L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Arch Neurol 64:1619-24. 2007
    ..Structural magnetic resonance imaging (MRI) has been used to investigate the in vivo pathology of frontotemporal lobar degeneration. However, few neuroimaging studies have focused on white matter (WM) alterations in this disease...
  48. pmc ASL perfusion MRI predicts cognitive decline and conversion from MCI to dementia
    Linda L Chao
    Center for Imaging of Neurodegenerative Disease, San Francisco, CA, USA
    Alzheimer Dis Assoc Disord 24:19-27. 2010
    ..03). These results suggest that hypoperfusion as detected by ASL-MRI can predict subsequent clinical, functional, and cognitive decline and may be useful for identifying candidates for future Alzheimer disease treatment trials...
  49. pmc Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease
    Juan Zhou
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA 94117, USA
    Brain 133:1352-67. 2010
    ..Further developed, intrinsic connectivity network signatures may provide simple, inexpensive, and non-invasive biomarkers for dementia differential diagnosis and disease monitoring...
  50. pmc Concordance and discordance between brain perfusion and atrophy in frontotemporal dementia
    Soichiro Shimizu
    Center for Imaging of Neurodegenerative Diseases, Veterans Affairs Medical Center, Department of Radiology and Biomedical Imaging, University of California, San Francisco, 4150 Clement Street, 114M, San Francisco, CA 94121, USA
    Brain Imaging Behav 4:46-54. 2010
    ..Detection of discordance between brain perfusion and structure in FTD might aid diagnosis and staging of the disease...
  51. pmc Cognitive and neuroimaging predictors of instrumental activities of daily living
    Deborah A Cahn-Weiner
    Department of Neurology, University of California, San Francisco, California 94143 0138, USA
    J Int Neuropsychol Soc 13:747-57. 2007
    ..Perhaps executive function is particularly important with respect to maintaining IADLs. Alternatively, executive dysfunction may be a sentinel event indicating widespread cortical involvement and poor prognosis...
  52. pmc Do tests of executive functioning predict ability to downregulate emotions spontaneously and when instructed to suppress?
    Anett Gyurak
    Institute of Personality and Social Research, Department of Psychology, University of California, Berkeley, California 94720 5050, USA
    Cogn Affect Behav Neurosci 9:144-52. 2009
    ....
  53. pmc Distinct neuroanatomical substrates and cognitive mechanisms of figure copy performance in Alzheimer's disease and behavioral variant frontotemporal dementia
    Katherine L Possin
    University of California, 350 Parnassus Ste 905, San Francisco, CA 94143 1207, United States
    Neuropsychologia 49:43-8. 2011
    ..Alternative methods of visual spatial assessment for dementia evaluations are proposed...
  54. pmc Patterns of cerebral hypoperfusion in amnestic and dysexecutive MCI
    Linda L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Alzheimer Dis Assoc Disord 23:245-52. 2009
    ..These data further suggest that cognitive impairment in MCI is related to cerebral hypoperfusion...
  55. ncbi Emotion comprehension in the temporal variant of frontotemporal dementia
    Howard J Rosen
    Department of Neurology, Memory and Aging Center, University of California at San Francisco, 350 Parnassus Avenue, Suite 800, Box 1207, San Francisco, CA 94143 1207, USA
    Brain 125:2286-95. 2002
    ..These results have implications both for the clinical presentation in tvFTD patients and for the study of the neuroanatomical basis of emotion...
  56. pmc Longitudinal volumetric MRI change and rate of cognitive decline
    D Mungas
    Department of Neurology, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA
    Neurology 65:565-71. 2005
    ..To examine how baseline and change of volumetric MRI relate to cognitive decline in older individuals...
  57. pmc Intrinsic connectivity networks in healthy subjects explain clinical variability in Alzheimer's disease
    Manja Lehmann
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA 94158, USA
    Proc Natl Acad Sci U S A 110:11606-11. 2013
    ..Our findings indicate that the posterior DMN and precuneus network are commonly affected in AD variants, whereas syndrome-specific neurodegenerative patterns are driven by the involvement of specific networks outside the DMN. ..
  58. pmc Patterns of brain atrophy in clinical variants of frontotemporal lobar degeneration
    Po H Lu
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Dement Geriatr Cogn Disord 35:34-50. 2013
    ..Using magnetic resonance imaging (MRI), tensor-based morphometry (TBM) was used to determine distinct patterns of atrophy between these three clinical groups...
  59. ncbi Fresh blood and aged stored blood are equally efficacious in immediately reversing anemia-induced brain oxygenation deficits in humans
    Richard B Weiskopf
    Department of Anesthesia and Cardiovascular Research Institute, University of California, San Francisco, USA
    Anesthesiology 104:911-20. 2006
    ..The authors tested the hypothesis that erythrocytes stored for 3 weeks are as effective in supplying oxygen to human tissues as are erythrocytes stored for less than 5 h...
  60. ncbi Response bias and aging on a recognition memory task
    Terri J Huh
    Department of Psychiatry, Memory and Aging Center, University of California San Francisco, California 94143, USA
    J Int Neuropsychol Soc 12:1-7. 2006
    ..In the light of reported relationships between frontal regions and both aging and response bias, we hypothesize that frontal changes may be the underlying mechanism explaining the increase in liberal response bias with age...
  61. ncbi Neuropsychological and functional measures of severity in Alzheimer disease, frontotemporal dementia, and semantic dementia
    Howard J Rosen
    Department of Neurology, Memory and Aging Center, University of California at San Francisco, San Francisco, California 94143 1207, USA
    Alzheimer Dis Assoc Disord 18:202-7. 2004
    ..Thus, in FTD the CDR reveals functional impairments in a wide variety of domains that are more severe than those seen in AD or SD patients with an equivalent Mini-Mental State Examination...
  62. ncbi Recognition of emotion in the frontal and temporal variants of frontotemporal dementia
    Howard J Rosen
    Department of Neurology, University of California, Memory and Aging Center, San Francisco, Calif, USA
    Dement Geriatr Cogn Disord 17:277-81. 2004
    ..These results suggest that damage to frontal lobe regions in FTD may lead to more profound impairment in recognition of emotion than when damage is more limited to the temporal lobe...
  63. pmc Anti-saccade performance predicts executive function and brain structure in normal elders
    Jacob B Mirsky
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, CA 94143, USA
    Cogn Behav Neurol 24:50-8. 2011
    ..To assess the neuropsychological and anatomical correlates of anti-saccade (AS) task performance in normal elders...
  64. ncbi Mental flexibility: age effects on switching
    Nancy S Wecker
    San Francisco, CA 94131, USA
    Neuropsychology 19:345-52. 2005
    ..The results are discussed in terms of theories of executive control and neurologic correlates across the adult life span...
  65. pmc Neonatal watershed brain injury on magnetic resonance imaging correlates with verbal IQ at 4 years
    Kyle J Steinman
    MAS, University of California, Division of Child Neurology, 350 Parnassus Ave, Suite 609, San Francisco, CA 94117, USA
    Pediatrics 123:1025-30. 2009
    ....
  66. pmc Neuroanatomical correlates of cognitive self-appraisal in neurodegenerative disease
    Howard J Rosen
    Department of Neurology, University of California at San Francisco, San Francisco, CA, USA
    Neuroimage 49:3358-64. 2010
    ..We hypothesize that emotional/physiological processing carried out by vmPFC is an important factor mediating self-appraisal accuracy in dementia...
  67. ncbi Clinical and neuropsychological features in autopsy-defined vascular dementia
    Bruce R Reed
    Alzheimer s Disease Center, University of California, Davis 94553, USA
    Clin Neuropsychol 18:63-74. 2004
    ..A illustrative case example is included. We conclude that the profile of cognitive impairment in IVD is highly variable, but that in clinical settings neuropsychological readings may contribute to the differential diagnosis of dementia...
  68. pmc Know thyself: real-world behavioral correlates of self-appraisal accuracy
    Casey E Krueger
    Department of Neurology, University of California San Francisco, San Francisco, CA, USA
    Clin Neuropsychol 25:741-56. 2011
    ....
  69. pmc Spontaneous social behaviors discriminate behavioral dementias from psychiatric disorders and other dementias
    Katherine P Rankin
    Department of Neurology, University of California, San Francisco 94143 1207, USA
    J Clin Psychiatry 69:60-73. 2008
    ..The object of this study was to improve screening for behavioral dementias in primary care and mental health settings by quantifying spontaneous social behaviors specific to FTLD...
  70. pmc Let's inhibit our excitement: the relationships between Stroop, behavioral disinhibition, and the frontal lobes
    Lara H Heflin
    Department of Neurology, Memory and Aging Center, University of California, San Francisco Medical Center, USA
    Neuropsychology 25:655-65. 2011
    ..This study tested those interpretations by examining relationships between Stroop performance, behavioral disinhibition, and frontal lobe atrophy...
  71. pmc Right and left medial orbitofrontal volumes show an opposite relationship to agreeableness in FTD
    Katherine P Rankin
    University of California San Francisco, San Francisco, Calif, USA
    Dement Geriatr Cogn Disord 17:328-32. 2004
    ..These data support the hypothesis that regulation of agreeableness arises from a balanced, mutually inhibitory circuit involving both hemispheres...
  72. ncbi Psychometrically matched measures of global cognition, memory, and executive function for assessment of cognitive decline in older persons
    Dan Mungas
    Department of Neurology, School of Medicine, University of California, Davis, Sacramento 95817, USA
    Neuropsychology 17:380-92. 2003
    ..Association of measures with quantitative structural magnetic resonance imaging variables followed expected patterns. This approach to scale development may have applications for other neuropsychological assessment problems...
  73. pmc Longitudinal rates of lobar atrophy in frontotemporal dementia, semantic dementia, and Alzheimer's disease
    Casey E Krueger
    UCSF Department of Neurology, San Francisco, CA, USA
    Alzheimer Dis Assoc Disord 24:43-8. 2010
    ..Measuring specific regions of cerebral volume changes by serial neuroimaging may serve as a useful biomarker outcome measure for clinical trials in neurodegenerative diseases...
  74. ncbi Hemispheric dominance for emotions, empathy and social behaviour: evidence from right and left handers with frontotemporal dementia
    R J Perry
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, California 94143, USA
    Neurocase 7:145-60. 2001
    ..The other left hander showed the opposite pattern of deficits, suggesting a novel presentation of anomalous dominance with reversed hemispheric specialization of semantic memory and emotional processing...
  75. pmc Emotional reactivity and emotion recognition in frontotemporal lobar degeneration
    K H Werner
    Department of Psychology, University of California, Berkeley, CA 94720 1650, USA
    Neurology 69:148-55. 2007
    ....
  76. pmc Computer-based cognitive training for mild cognitive impairment: results from a pilot randomized, controlled trial
    Deborah E Barnes
    Department of Psychiatry, University of California San Francisco, 4150 Clement Street 151R, San Francisco, CA 94121, USA
    Alzheimer Dis Assoc Disord 23:205-10. 2009
    ..We conclude that intensive, computer-based mental activity is feasible in subjects with mild cognitive impairment and that larger trials are warranted...
  77. pmc Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
    Katya Rascovsky
    Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, 3 West Gates, Philadelphia, PA 19104, USA
    Brain 134:2456-77. 2011
    ..Future studies will be needed to establish the reliability and specificity of these revised diagnostic guidelines...
  78. pmc Perioperative cognitive decline in the aging population
    Niccolò Terrando
    Department of Anesthesia and Perioperative Care, San Francisco, CA 94143 0648, USA
    Mayo Clin Proc 86:885-93. 2011
    ..A road map to further elucidate the mechanisms, diagnosis, risk factors, mitigation, and treatment of postoperative cognitive decline in the elderly is provided...
  79. ncbi Patterns of autobiographical memory loss in dementia
    Craig E Hou
    UCSF Memory and Aging Center, Department of Neurology, University of California at San Francisco, 350 Parnassus Avenue, Box 1207 San Francisco, CA 94143, USA
    Int J Geriatr Psychiatry 20:809-15. 2005
    ..Several studies have found impaired recall of remote autobiographical memories relative to recent memories in semantic dementia (SD), a pattern opposite to that in Alzheimer's disease (AD)...
  80. ncbi Clinical and neuropsychological features of corticobasal degeneration
    Nataliya Belfor
    University of California San Francisco, Memory and Aging Center, 350 Parnassus Avenue, Suite 705, 94143, USA
    Mech Ageing Dev 127:203-7. 2006
    ..Increasing awareness of this disorder has led to the realization that specific cognitive and imaging changes are common with CBD degeneration and that these changes help with clinical diagnosis...
  81. pmc Cognitive and neuropsychiatric profile of the synucleinopathies: Parkinson disease, dementia with Lewy bodies, and multiple system atrophy
    Aimee W Kao
    Department of Neurology, University of California San Francisco, 94143, USA
    Alzheimer Dis Assoc Disord 23:365-70. 2009
    ..PD, MSA, and DLB groups have similar neuropsychiatric profiles of increased depression and anxiety. Similar underlying alpha-synuclein pathology may contribute to these shared features...
  82. pmc Volumetric MRI predicts rate of cognitive decline related to AD and cerebrovascular disease
    D Mungas
    Department of Neurology, School of Medicine, University of California, Davis, USA
    Neurology 59:867-73. 2002
    ..To examine volumetric MRI correlates of longitudinal cognitive decline in normal aging, AD, and subcortical cerebrovascular brain injury (SCVBI)...
  83. ncbi A voxel-based morphometry study of patterns of brain atrophy in ALS and ALS/FTLD
    J L Chang
    Department of Neurology, University of California San Francisco, CA, USA
    Neurology 65:75-80. 2005
    ..To investigate the patterns of MRI brain atrophy in patients with ALS with and without clinically evident frontotemporal lobar dementia (FTLD) using voxel-based morphometry (VBM)...
  84. ncbi Longitudinal tracking of FTLD: toward developing clinical trial methodology
    David S Knopman
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Alzheimer Dis Assoc Disord 21:S58-63. 2007
    ..In addition, a multicenter trial is described in which some aspects of diagnosis and longitudinal measurement in the frontotemporal lobar degenerations are being specifically explored...
  85. pmc The early neuropsychological and behavioral characteristics of frontotemporal dementia
    Dana Wittenberg
    Memory and Aging Center, University of California San Francisco Medical Center, San Francisco, CA, USA
    Neuropsychol Rev 18:91-102. 2008
    ..As this review underscores, frontotemporal dementia remains a powerful model for studying brain-behavior relationships...
  86. pmc Joint assessment of structural, perfusion, and diffusion MRI in Alzheimer's disease and frontotemporal dementia
    Yu Zhang
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs San Francisco VA, Medical Center, 4150, Clement Street, San Francisco, CA 94121, USA
    Int J Alzheimers Dis 2011:546871. 2011
    ..Joint assessments of multimodal MRI have potential value to provide new imaging markers for improved differential diagnoses between FTD and AD...
  87. ncbi Are amyotrophic lateral sclerosis patients cognitively normal?
    C Lomen-Hoerth
    Department of Neurology, University of California at San Francisco, 94143, USA
    Neurology 60:1094-7. 2003
    ..In many instances, the frontal executive deficits represent the co-occurrence of frontotemporal lobar dementia (FTLD) and ALS...
  88. pmc Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease
    A T Du
    Magnetic Resonance Unit, Department of Veterans Affairs Medical Center (114M, University of California, San Francisco 94121, USA
    J Neurol Neurosurg Psychiatry 71:441-7. 2001
    ..CONCLUSIONS: Volume reductions in the ERC and hippocampus may be early signs of AD pathology that can be measured using MRI...
  89. pmc Effects of subcortical ischemic vascular dementia and AD on entorhinal cortex and hippocampus
    A T Du
    Magnetic Resonance Unit, Department of Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Neurology 58:1635-41. 2002
    ..To determine the effects of subcortical ischemic vascular dementia (SIVD) and AD on entorhinal cortex (ERC) and hippocampus...
  90. ncbi Challenging the clinical utility of the 14-3-3 protein for the diagnosis of sporadic Creutzfeldt-Jakob disease
    Michael D Geschwind
    Department of Neurology, University of California, San Francisco Medical Center, San Francisco, CA 94143, USA
    Arch Neurol 60:813-6. 2003
    ..Previous studies have suggested that, in the proper clinical context, the 14-3-3 protein in cerebrospinal fluid is a reliable marker for sporadic CJD...
  91. ncbi Patterns of cerebral atrophy in primary progressive aphasia
    Howard J Rosen
    Department of Neurology, Memory and Aging Center, University of California at San Francisco, CA 94143 1207, USA
    Am J Geriatr Psychiatry 10:89-97. 2002
    ..Different clinical syndromes in PPA are associated with different patterns of atrophy. In the future, combined analysis of imaging and clinical characteristics may allow more accurate etiologic diagnosis...
  92. ncbi Continuum of frontal lobe impairment in amyotrophic lateral sclerosis
    Jennifer M Murphy
    Department of Neurology, ALS Center, University of California, San Francisco, CA 94117, USA
    Arch Neurol 64:530-4. 2007
    ..To identify the nature and prevalence of cognitive and behavioral abnormalities in patients with amyotrophic lateral sclerosis (ALS)...
  93. ncbi Very early-onset familial Alzheimer's disease: a novel presenilin 1 mutation
    Jill S Goldman
    UCSF Memory and Aging Center, San Francisco, CA 94143, USA
    Int J Geriatr Psychiatry 17:649-51. 2002
    ..Early-onset familial Alzheimer's disease (EOFAD) is linked to mutations in three autosomal dominant genes: PS1, PS2 and APP. The clinical presentation and age of onset of mutations is variable...
  94. ncbi Patterns of cognitive and emotional empathy in frontotemporal lobar degeneration
    Katherine P Rankin
    Memory and Aging Center, University of California San Francisco, California 94145 1203, USA
    Cogn Behav Neurol 18:28-36. 2005
    ..To examine the relationship between empathy and cognition in frontotemporal lobar degeneration (FTLD)...
  95. ncbi Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): current limitations and future directions
    Katya Rascovsky
    Memory and Aging Center, University of California, San Francisco, CA 94117, USA
    Alzheimer Dis Assoc Disord 21:S14-8. 2007
    ..In this article, we discuss the limitations of current diagnostic criteria and propose the establishment of an international consortium to revise diagnostic and research criteria for the behavioral variant of frontotemporal dementia...
  96. pmc Mild cognitive impairment, dementia, and their subtypes in oldest old women
    Kristine Yaffe
    Department of Psychiatry, University of California at San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
    Arch Neurol 68:631-6. 2011
    ..The population of oldest old is increasing, but the prevalence of cognitive impairment is not well characterized in this group...
  97. pmc Double dissociation of social functioning in frontotemporal dementia
    Katherine P Rankin
    University of California San Francisco, USA
    Neurology 60:266-71. 2003
    ..Efforts to characterize changes in social functioning in frontotemporal dementia (FTD) have failed to elicit clear dissociation between frontal and temporal variants of the disease based on behavioral measures...
  98. ncbi Oxygen reverses deficits of cognitive function and memory and increased heart rate induced by acute severe isovolemic anemia
    Richard B Weiskopf
    Department of Anesthesia, University of California, San Francisco, California 94143 0648, USA
    Anesthesiology 96:871-7. 2002
    ....
  99. ncbi DHEA treatment of Alzheimer's disease: a randomized, double-blind, placebo-controlled study
    O M Wolkowitz
    Department of Psychiatry, Center for Neurobiology and Psychiatry, University of California San Francisco UCSF School of Medicine, USA
    Neurology 60:1071-6. 2003
    ..To compare the efficacy and tolerability of dehydroepiandrosterone (DHEA) vs placebo in AD...
  100. pmc MRI predictors of cognition in subcortical ischemic vascular disease and Alzheimer's disease
    D Mungas
    Department of Neurology, School of Medicine University of California, Davis 95817, USA
    Neurology 57:2229-35. 2001
    ....
  101. ncbi Utility of clinical criteria in differentiating frontotemporal lobar degeneration (FTLD) from AD
    Howard J Rosen
    Department of Neurology, Memory and Aging Center, University of California at San Francisco, 350 Parnassus Avenue, Suite 800, San Francisco, CA 94143 1207, USA
    Neurology 58:1608-15. 2002
    ..To assess the ability of the current diagnostic criteria for frontotemporal lobar degeneration (FTLD) to differentiate FTLD from AD...