Research Topics
| Frank A KozelSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
Research Grants
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Detail Information
Publications
Decision analysis of the cost-effectiveness of repetitive transcranial magnetic stimulation versus electroconvulsive therapy for treatment of nonpsychotic severe depressionF Andrew Kozel
Brain Stimulation Laboratory, Department of Psychiatry, Medical University of South Carolina, and Ralph H Johnson Veterans Affairs Medical Center, Charleston, USA
CNS Spectr 9:476-82. 2004..Repetitive transcranial magnetic stimulation (rTMS) is a new treatment with promise for resistant depression...
The neuroscience of functional magnetic resonance imaging fMRI for deception detectionKevin A Johnson
Medical University of South Carolina, USA
Am J Bioeth 7:58-60. 2007
Feature selection for fMRI-based deception detectionBo Jin
Medical University of South Carolina, Charleston, SC, USA
BMC Bioinformatics 10:S15. 2009..In this paper, we investigated the procedures of feature selection to enhance fMRI-based deception detection...
Fractional anisotropy changes after several weeks of daily left high-frequency repetitive transcranial magnetic stimulation of the prefrontal cortex to treat major depressionF Andrew Kozel
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
J ECT 27:5-10. 2011..A decrease in fractional anisotropy values of the left prefrontal WM could indicate damage to the region...
Treatment outcomes for older depressed patients with earlier versus late onset of first depressive episode: a Sequenced Treatment Alternatives to Relieve Depression (STAR*D) reportF Andrew Kozel
Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
Am J Geriatr Psychiatry 16:58-64. 2008..In this study of older depressed outpatients, the authors evaluated whether the age at onset of the first major depressive episode (MDE) was related to clinical outcomes...
Can simultaneously acquired electrodermal activity improve accuracy of fMRI detection of deception?F Andrew Kozel
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9119, USA
Soc Neurosci 4:510-7. 2009..Further work is required to test whether EDA improves accuracy in other testing formats or with higher levels of jeopardy...
Detecting deception using functional magnetic resonance imagingF Andrew Kozel
Center for Advanced Imaging Research CAIR, Medical University of South Carolina, Charleston, SC, USA
Biol Psychiatry 58:605-13. 2005..e., conduct disorder, antisocial personality disorder, etc.)...
Developing a neuropsychiatric functional brain imaging testF Andrew Kozel
Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9119, USA
Neurocase 14:54-8. 2008..Incorporating what has been learned with medical diagnostic test development will enable legitimate and significant neuropsychiatric functional brain imaging tests to be developed in the future...
Using simultaneous repetitive Transcranial Magnetic Stimulation/functional Near Infrared Spectroscopy (rTMS/fNIRS) to measure brain activation and connectivityF Andrew Kozel
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9119, USA
Neuroimage 47:1177-84. 2009..In addition, the effects of rTMS in distinct brain regions without quantifiable behavioral changes can be objectively measured...
Serial vagus nerve stimulation functional MRI in treatment-resistant depressionZiad Nahas
Department of Psychiatry, Brain Stimulation Laboratory, Mood Disorders Program, Institute of Psychiatry, Charleston, SC 29403, USA
Neuropsychopharmacology 32:1649-60. 2007..Future interleaved VNS/fMRI studies to confirm these findings and further clarify the regional neurobiological effects of VNS...
Decreased brain activation during a working memory task at rested baseline is associated with vulnerability to sleep deprivationQiwen Mu
Brain Stimulation Laboratory, Medical University of South Carolina IOP, 502 N, 67 President St, Charleston, SC 29425, USA
Sleep 28:433-46. 2005..To examine whether differences in patterns of brain activation under baseline conditions relate to the differences in sleep-deprivation vulnerability...
A pilot study of functional magnetic resonance imaging brain correlates of deception in healthy young menF Andrew Kozel
Center for Advanced Imaging Research, Department of Psychiatry, Medical University of South Carolina, South Carolina, USA
J Neuropsychiatry Clin Neurosci 16:295-305. 2004..Individually and as a group, EDA correlated with blood flow changes in the OFCx and AC. Specific brain regions were activated during deception, but the present technique lacks good predictive power for individuals...
Functional MRI detection of deception after committing a mock sabotage crimeF Andrew Kozel
Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9119, USA
J Forensic Sci 54:220-31. 2009..BOLD fMRI presently can be used to detect deception concerning past events with high sensitivity, but low specificity...
Interleaved transcranial magnetic stimulation/functional MRI confirms that lamotrigine inhibits cortical excitability in healthy young menXingbao Li
Brain Stimulation Laboratory, Center for Advanced Imaging Research CAIR, Medical University of South Carolina MUSC, Charleston, SC 29425, USA
Neuropsychopharmacology 29:1395-407. 2004..Furthermore, the interleaved TMS/fMRI technique may be a useful tool for investigating regional brain effects of psychoactive compounds...
Safety and benefits of distance-adjusted prefrontal transcranial magnetic stimulation in depressed patients 55-75 years of age: a pilot studyZiad Nahas
Brain Stimulation Laboratory, Institute of Psychiatry, Medical University of South Carolina, Charleston, SC 29425, USA
Depress Anxiety 19:249-56. 2004....
Cost-effectiveness of transcranial magnetic stimulation in the treatment of major depression: a health economics analysisKit N Simpson
Medical University of South Carolina, 67 President Street, Room 502N, Charleston, SC, 29403, USA
Adv Ther 26:346-68. 2009..The incremental cost-effectiveness and the direct cost burden compared with sham treatment were estimated, and compared with the current standard of care...
Acute left prefrontal transcranial magnetic stimulation in depressed patients is associated with immediately increased activity in prefrontal cortical as well as subcortical regionsXingbao Li
Brain Stimulation Laboratory, Department of Psychiatry, Charleston, South Carolina 29425, USA
Biol Psychiatry 55:882-90. 2004..Further work is needed to understand whether these immediate changes vary as a function of TMS use parameters (intensity, frequency, location) and whether they relate to neurobiologic effects and antidepressant mechanisms of TMS...
Research Grants
- Investigating Neurocircuitry of Geriatric DepressionFRANK KOZEL; Fiscal Year: 2007..The numerous clinical trials of mood disorders presently ongoing at UTSW provide a wealth of subjects for which different imaging hypotheses can be developed and tested...
