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Species | Laura KoutskySummaryAffiliation: University of Washington Country: USA Publications
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Chapter 13: Current findings from prophylactic HPV vaccine trialsLaura A Koutsky
Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195, USA
Vaccine 24:S3/114-21. 2006..Both vaccines have the potential to substantially reduce HPV-related morbidity and mortality. This review focuses on published data from clinical trials of these two vaccines...
The epidemiology behind the HPV vaccine discoveryLaura Koutsky
Department of Epidemiology, School of Public Health, University of Washington, 155 NE 100th St, Seattle, WA 98125
Ann Epidemiol 19:239-44. 2009..Presented below is one epidemiologist's perspective on events that contributed to these scientific achievements...- A controlled trial of a human papillomavirus type 16 vaccineLaura A Koutsky
Department of Epidemiology, University of Washington, Seattle, USA
N Engl J Med 347:1645-51. 2002..Although most infections are benign, some progress to anogenital cancer. A vaccine that reduces the incidence of HPV-16 infection may provide important public health benefits... - Cigarette smoking, oncogenic human papillomavirus, Ki-67 antigen, and cervical intraepithelial neoplasiaTiffany G Harris
Department of Epidemiology, University of Washington, Seattle, WA, USA
Am J Epidemiol 159:834-42. 2004..Since smoking was associated with both CIN1 and >/= CIN2-3, cigarette by-products may affect the early evolution of HPV-related lesions, possibly by increasing the rate of cell turnover... - Evaluation of human papillomavirus testing in primary screening for cervical abnormalities: comparison of sensitivity, specificity, and frequency of referralShalini L Kulasingam
Department of Epidemiology, University of Washington, Seattle, WA, USA
JAMA 288:1749-57. 2002..In some settings, particularly where screening intervals are long or haphazard, screening for HPV DNA may be a reasonable alternative to cytology-based screening of reproductive-age women... - Acquisition and natural history of human papillomavirus type 16 variant infection among a cohort of female university studentsLong Fu Xi
Department of Pathology, School of Medicine, University of Washington, Seattle, Washington 98103, USA
Cancer Epidemiol Biomarkers Prev 11:343-51. 2002.... - Genital human papillomavirus infection: incidence and risk factors in a cohort of female university studentsRachel L Winer
Department of Epidemiology, University of Washington, Seattle, WA 98103, USA
Am J Epidemiol 157:218-26. 2003..The data show that the incidence of HPV associated with acquisition of a new sex partner is high and that nonpenetrative sexual contact is a plausible route of transmission in virgins... - Characterization of IgA response among women with incident HPV 16 infectionTakashi Onda
Program in Cancer Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA
Virology 312:213-21. 2003..6 months for serum IgA, whereas approximately 20% of women with serum IgG antibodies reverted within 36 months. Thus, the duration of IgA in cervical secretions and sera was shorter than the duration of serum IgG (P = 0.007 and 0.001)... - Liquid-based Papanicolaou smears without a transformation zone component: should clinicians worry?Atar Baer
Department of Epidemiology, University of Washington, Seattle, Washington 98103, USA
Obstet Gynecol 99:1053-9. 2002..To evaluate whether ThinPrep smears without versus those with a transformation zone component were more likely to have falsely negative cytology findings... - Persistence of genital human papillomavirus infection in a long-term follow-up study of female university studentsLaura K Sycuro
Departments of Epidemiology, University of Washington, Seattle, WA 98103, USA
J Infect Dis 198:971-8. 2008..Little is known about the epidemiology of human papillomavirus (HPV) infections that persist for more than a few years... - Genital human papillomavirus infection in men: incidence and risk factors in a cohort of university studentsJeffrey M Partridge
Department of Epidemiology, University of Washington, Seattle, WA 98103, USA
J Infect Dis 196:1128-36. 2007..In contrast to the wealth of data on human papillomavirus (HPV) infections in women, much less is known about HPV in men... - Evaluation of an ELISA for p16INK4a as a screening test for cervical cancerAkhila Balasubramanian
Department of Epidemiology, University of Washington, Seattle, Washington, USA
Cancer Epidemiol Biomarkers Prev 18:3008-17. 2009..The low sensitivity of cytology and low specificity of human papillomavirus testing prompts searching for more accurate cervical cancer screening strategies. Our goal was to evaluate an ELISA-based test for p16(INK4a)... 
Age of diagnosis of squamous cell cervical carcinoma and early sexual experienceZoe R Edelstein
University of Washington, HPV Research Group, Seattle, WA 98103, USA
Cancer Epidemiol Biomarkers Prev 18:1070-6. 2009....- Clinical findings among young women with genital human papillomavirus infectionConstance Mao
Department of Obstetrics and Gynecology, University of Washington, Seattle, USA
Am J Obstet Gynecol 188:677-84. 2003..Furthermore, a time lag analysis suggests that HPV infection usually precedes detection of BV. CONCLUSION: Most women who acquire genital HPV infection are asymptomatic; some, however, are at increased risk for BV... - Factors that are associated with parental acceptance of human papillomavirus vaccines: a randomized intervention study of written information about HPVAmanda F Dempsey
Robert Wood Johnson Clinical Scholars Program, University of Washington, Seattle, Washington, USA
Pediatrics 117:1486-93. 2006.... - The effect of vaginal speculum lubrication on the rate of unsatisfactory cervical cytology diagnosisAnne Marie E Amies
Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, Washington 98195, USA
Obstet Gynecol 100:889-92. 2002..We wanted to see if application of water-soluble gel lubricant to the plastic vaginal speculum would change the unsatisfactory cervical cytology diagnosis rate... - Antibody responses in oral fluid after administration of prophylactic human papillomavirus vaccinesAli Rowhani-Rahbar
Department of Epidemiology, University of Washington, Seattle, WA 98125, USA
J Infect Dis 200:1452-5. 2009..6% (95% confidence interval [CI], 42.0%-57.3%) before and 100% (95% CI, 92.0%-100%) after administration of the quadrivalent vaccine. Oral fluid may have the potential to be used for monitoring of prophylactic HPV vaccines in the future... - Risk of cervical intraepithelial neoplasia grade 2 or 3 after loop electrosurgical excision procedure associated with human papillomavirus type 16 variantsLong Fu Xi
Department of Pathology, School of Medicine, University of Washington, Seattle, WA 98103, USA
J Infect Dis 195:1340-4. 2007..1 (95% confidence interval, 1.1-8.9) was associated with HPV16 non-European, compared with European, variants, a finding that is consistent with the variant-related risk of prevalent/incident high-grade CIN... - Evaluation of a new p16(INK4A) ELISA test and a high-risk HPV DNA test for cervical cancer screening: results from proof-of-concept studyConstance Mao
Department of Obstetrics and Gynecology, University of Washington, Seattle, WA 98104 2499, USA
Int J Cancer 120:2435-8. 2007..These findings support proceeding with a larger study with samples from a population of women presenting for routine cytology screening... - Risk for high-grade cervical intraepithelial neoplasia associated with variants of human papillomavirus types 16 and 18Long Fu Xi
Department of Pathology, School of Medicine, University of Washington, Seattle, Washington 98103, USA
Cancer Epidemiol Biomarkers Prev 16:4-10. 2007..Although the variant lineages of human papillomavirus (HPV) types 16 and 18 are well established, their individual associations with high-grade cervical intraepithelial neoplasia (CIN) have not been extensively evaluated... - Concordance of self-collected and clinician-collected swab samples for detecting human papillomavirus DNA in women 18 to 32 years of ageRachel L Winer
Department of Epidemiology, University of Washington, Seattle, Washington, USA
Sex Transm Dis 34:371-7. 2007..The objective of this study was to determine whether self- and clinician-collected samples are comparable for human papillomavirus (HPV) detection... - Human papillomavirus type 16 variants in paired enrollment and follow-up cervical samples: implications for a proper understanding of type-specific persistent infectionsLong Fu Xi
Department of Pathology, School of Medicine, University of Washington, Seattle 98104, USA
J Infect Dis 202:1667-70. 2010..11). These results suggest the possibility that rare misclassification of transient infections as persistent infections occurs in natural history studies of type-specific HPV infections... - Longer term efficacy of a prophylactic monovalent human papillomavirus type 16 vaccineAli Rowhani-Rahbar
Department of Epidemiology, University of Washington, Seattle, WA 98125, USA
Vaccine 27:5612-9. 2009..The results suggest that this monovalent HPV-16 vaccine remains efficacious through 8.5 years after its administration... - Detection of genital HPV types in fingertip samples from newly sexually active female university studentsRachel L Winer
University of Washington HPV Research Group, Box 359933, 325 9th Avenue, Seattle, WA 98104, USA
Cancer Epidemiol Biomarkers Prev 19:1682-5. 2010..The study objectives were to determine the presence of genital HPV types in fingertip samples and the agreement between fingertip and genital samples for detecting HPV... - Risk of female human papillomavirus acquisition associated with first male sex partnerRachel L Winer
Department of Epidemiology, University of Washington, Seattle, WA 98103, USA
J Infect Dis 197:279-82. 2008..6%-38.6%) and increased to almost 50% by 3 years. The risk was increased when the first male partner was sexually experienced. Our results indicate a high risk of HPV infection in young women who have had just 1 male sex partner... - Evaluation of primary cervical cancer screening with an oncogenic human papillomavirus DNA test and cervical cytologic findings among women who attended family planning clinics in the United StatesJanet G Baseman
Department of Epidemiology, University of Washington, Seattle, WA, USA
Am J Obstet Gynecol 199:26.e1-8. 2008.... - Effect of cervical cytologic status on the association between human papillomavirus type 16 DNA load and the risk of cervical intraepithelial neoplasia grade 3Long Fu Xi
Department of Pathology, School of Medicine, University of Washington, Seattle, Washington 98103, USA
J Infect Dis 198:324-31. 2008.... - Relationship between cigarette smoking and human papilloma virus types 16 and 18 DNA loadLong Fu Xi
Department of Pathology, University of Washington, Seattle, USA
Cancer Epidemiol Biomarkers Prev 18:3490-6. 2009..Although cigarette smoking has been associated with increased human papilloma virus (HPV) detection, its impact on HPV DNA load is unknown... - Development and evaluation of a liquid bead microarray assay for genotyping genital human papillomavirusesQinghua Feng
Department of Pathology, University of Washington, School of Public Health and Community Medicine, Seattle, Washington 98109, USA
J Clin Microbiol 47:547-53. 2009..The repeat test reproducibility for 100 samples was 99.1% (kappa=0.92; 95% CI, 0.90 to 0.95). We conclude that the new LBMA assay will be useful for clinical and epidemiological research... - Human papillomavirus type 18 DNA load and 2-year cumulative diagnoses of cervical intraepithelial neoplasia grades 2-3Long Fu Xi
Department of Pathology, School of Medicine, University of Washington, 1914 North 34th St, Suite 300, Seattle, WA 98103, USA
J Natl Cancer Inst 101:153-61. 2009..The clinical relevance of the amount of human papillomavirus type 18 (HPV18) DNA in cervical tissue (ie, HPV18 DNA load) is unknown... - Quantitative human papillomavirus 16 and 18 levels in incident infections and cervical lesion developmentRachel L Winer
Department of Epidemiology, University of Washington, Seattle, Washington, USA
J Med Virol 81:713-21. 2009..05, 95% CI = 1.09-92.56) and increased HPV DNA (VLR = 16.80, 95% CI = 1.46-193.01). In newly detected HPV-16 infections, increasing levels of E7 mRNA appear to be associated with an increased risk of developing cervical pre-cancer... - Human Papillomavirus (HPV) type 16 and type 18 DNA Loads at Baseline and Persistence of Type-Specific Infection during a 2-year follow-upLong Fu Xi
Department of Pathology, School of Medicine, University of Washington, Seattle, USA
J Infect Dis 200:1789-97. 2009..Studies of viral load-associated persistence of human papillomavirus (HPV) infection are rare, with inconsistent results reported... - Depot-medroxyprogesterone acetate and combined oral contraceptive use and cervical neoplasia among women with oncogenic human papillomavirus infectionTiffany G Harris
Department of Epidemiology, University of Washington School of Public Health and Community Medicine, Seattle, WA, USA
Am J Obstet Gynecol 200:489.e1-8. 2009..The objective of the study was to examine the relationship of depot-medroxyprogesterone acetate (DMPA) and combined oral contraceptive (COC) use with cervical intraepithelial neoplasia (CIN)... - Condom use and the risk of genital human papillomavirus infection in young womenRachel L Winer
Department of Epidemiology, University of Washington, Seattle, USA
N Engl J Med 354:2645-54. 2006.... - Characterization of vaginal flora and bacterial vaginosis in women who have sex with womenJeanne M Marrazzo
Department of Medicine, University of Washington, Seattle, WA 98104, USA
J Infect Dis 185:1307-13. 2002..These data support the hypothesis that sexual exchange of vaginal secretions is a possible mechanism for acquisition of BV... - The epidemiology of human papillomavirus infectionsJanet G Baseman
UW HPV Research Group, Lake Union Place, Suite 300, 1914 N 34th Street, Seattle, WA 98103, USA
J Clin Virol 32:S16-24. 2005..Finally, we discuss strategies for preventing HPV infection... - Evaluation of genital sites and sampling techniques for detection of human papillomavirus DNA in menBethany A Weaver
Center for AIDS and STD Research, Department of Medicine, University of Washington, Harborview Medical Center, 325 9th Avenue, Box 359931, Seattle, WA 98104 USA
J Infect Dis 189:677-85. 2004..The HPV prevalence was similar for circumcised and uncircumcised men. Testing multiple sites increased the number of men for whom HPV DNA was detected... - Should liquid-based cytology be repeated at the time of colposcopy?Constance Mao
Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, USA
J Low Genit Tract Dis 9:82-8. 2005..To evaluate the usefulness of repeated liquid cytology at the time of colposcopy... - p16(INK4a) expression correlates with degree of cervical neoplasia: a comparison with Ki-67 expression and detection of high-risk HPV typesS Nicholas Agoff
Department of Pathology, University of Washington, Seattle, Washington 98195, USA
Mod Pathol 16:665-73. 2003..Although expression of p16(INK4a) in endometrial epithelium may be problematic in terms of screening, the potential of p16(INK4a) as a screening test warrants investigation... - Do condoms prevent genital HPV infection, external genital warts, or cervical neoplasia? A meta-analysisLisa E Manhart
Department of Medicine, University of Washington, Seattle, Washington, USA
Sex Transm Dis 29:725-35. 2002..Although condoms most likely prevent HIV infection, evidence of their effectiveness against other sexually transmitted diseases is mixed... - Human papillomavirus type 16 and 18 variants: race-related distribution and persistenceLong Fu Xi
Department of Pathology, School of Medicine, University of Washington, Seattle, WA, USA
J Natl Cancer Inst 98:1045-52. 2006.... - Human papillomavirus infection among sexually active young women in the United States: Implications for developing a vaccination strategyLisa E Manhart
Department of Epidemiology, University of Washington, Seattle, Washington, USA
Sex Transm Dis 33:502-8. 2006..Population-level data on prevalence and distribution of human papillomavirus (HPV) types in the United States are necessary to guide optimal vaccination strategies... - Development and duration of human papillomavirus lesions, after initial infectionRachel L Winer
Department of Epidemiology, University of Washington, Seattle, Washington 98103, USA
J Infect Dis 191:731-8. 2005..4%). CONCLUSIONS: Intraepithelial lesions are common early events among women with incident HPV infection, and the interval between incident HPV-16 or HPV-18 infection and biopsy-confirmed CIN grade 2-3 appears to be relatively short... - Comparison of incident cervical and vulvar/vaginal human papillomavirus infections in newly sexually active young womenRachel L Winer
Department of Epidemiology, University of Washington, Seattle 98103, USA
J Infect Dis 199:815-8. 2009..03). Site-by-species differences were not statistically significant. Our results suggest that low- or undetermined-risk HPV types preferentially infect vaginal epithelium... - Evaluation of transported dry and wet cervical exfoliated samples for detection of human papillomavirus infectionQinghua Feng
Department of Pathology, School of Medicine, University of Washington, 815 Mercer St, UW Medicine Box 358050, Seattle, WA 98109, USA
J Clin Microbiol 48:3068-72. 2010..6 times lower than those in matched STM samples. We concluded that exfoliated cervical cells could be collected as dry swab samples for HPV detection... - Efficacy of human papillomavirus-16 vaccine to prevent cervical intraepithelial neoplasia: a randomized controlled trialConstance Mao
Department of Obstetrics and Gynecology and Epidemiology, University of Washington, Seattle, Washington 98104 2499, USA
Obstet Gynecol 107:18-27. 2006..Whether protection lasts longer than 18 months and, thus, impacts rates of cervical intraepithelial neoplasia (CIN) 2-3 has not yet been established. We present results from an HPV16 L1 VLP vaccine trial through 48 months... - The theoretical population-level impact of a prophylactic human papilloma virus vaccineJames P Hughes
Department of Biostatistics, University of Washington, Seattle, WA 98195, USA
Epidemiology 13:631-9. 2002..The ongoing development of a vaccine against human papillomavirus (HPV) raises important questions about the impact of various vaccination strategies... - Humoral immune response recognizes a complex set of epitopes on human papillomavirus type 6 l1 capsomersJohnnie J Orozco
Program in Cancer Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA
J Virol 79:9503-14. 2005..Reactivity in two sera was not eliminated even with all six regions swapped. The patterns of epitope recognition did not change over time in women whose sera were examined 9 years after their first-seropositive visit... - Sequence variation of human papillomavirus type 16 and measurement of viral integration by quantitative PCRMingjun Jiang
Department of Pathology, School of Medicine, University of Washington, Seattle, Washington, USA
J Clin Microbiol 47:521-6. 2009.... - Genital human papillomavirus infection in menJeffrey M Partridge
Department of Epidemiology, University of Washington HPV Research Group, University of Washington, Seattle, WA 98103, USA
Lancet Infect Dis 6:21-31. 2006.... - Accuracy and cost-effectiveness of cervical cancer screening by high-risk human papillomavirus DNA testing of self-collected vaginal samplesAkhila Balasubramanian
Department of Epidemiology, University of Washington, Seattle, WA, USA
J Low Genit Tract Dis 14:185-95. 2010..Estimate the accuracy and cost-effectiveness of cervical cancer screening strategies based on high-risk human papillomavirus (HPV) DNA testing of self-collected vaginal samples... - Development of genital warts after incident detection of human papillomavirus infection in young menYuzo Arima
Departments of 1Epidemiology, and 6Harborview Medical Center, University of Washington, Seattle, WA 98104, USA
J Infect Dis 202:1181-4. 2010..7% (95% CI, 0.2%-2.8%) among 331 men who tested negative for HPV. Our results suggest that genital warts are common after HPV-6 or HPV-11 infection in young men... - Identification of human papillomavirus type 16 L1 surface loops required for neutralization by human seraJoseph J Carter
Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N MSC 015, P O Box 19024, Seattle, WA 98109 1024, USA
J Virol 80:4664-72. 2006..These observations are consistent with the existence of multiple neutralizing epitopes on the HPV virion surface... - Obtaining sensitive data through the Web: an example of design and methodsAtar Baer
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA, USA
Epidemiology 13:640-5. 2002..We also discuss compliance, as well as methods for assuring appropriate security, confidentiality and privacy... - Re: Specific antibody levels at the cervix during the menstrual cycle of women vaccinated with human papillomavirus 16 virus-like particlesEliav Barr
J Natl Cancer Inst 96:412-3; author reply 413-4. 2004 - Comparison of oral fluid and serum ELISAs in the determination of IgG response to natural human papillomavirus infection in university womenFarrel J Buchinsky
Center for Genomic Sciences, Allegheny Singer Research Institute, 320 E North Avenue, Pittsburgh, PA 15212 4772, USA
J Clin Virol 35:450-3. 2006..Venipuncture (phlebotomy) is an obstacle to subject recruitment and ongoing participation in cohort studies investigating human papillomavirus (HPV) infection. Anti-HPV antibodies are not only detected in serum but also in oral fluid... - Delivering reassurance to parents: perinatal human papillomavirus transmission is rareRachel L Winer
Sex Transm Dis 31:63-4. 2004 - Early assessment of the efficacy of a human papillomavirus type 16 L1 virus-like particle vaccineDarron R Brown
Department of Medicine, Indiana University School of Medicine, Emerson Hall Room 435, 545 Barnhill Drive, Indianapolis 46022, USA
Vaccine 22:2936-42. 2004..These results support the institution of larger efficacy trials for HPV L1 VLP vaccines... - Dose-ranging studies of the safety and immunogenicity of human papillomavirus Type 11 and Type 16 virus-like particle candidate vaccines in young healthy womenKenneth H Fife
Department of Medicine, Indiana University School of Medicine, Indianapolis, USA
Vaccine 22:2943-52. 2004..Antibody to HPV11 and 16 was still present at Month 36 in 96.8 and 93.5% of vaccinees, respectively. Both vaccines were well tolerated and were associated with only mild to moderate injection-site reactions... - Smokers at higher risk for undetected antibody for oncogenic human papillomavirus type 16 infectionDorothy J Wiley
School of Nursing, University of California at Los Angeles, Los Angeles, CA 90095 6919, USA
Cancer Epidemiol Biomarkers Prev 15:915-20. 2006..Main Outcome Measure: HPV16-L1 antibody (anti-HPV16 antibody) detected from serum using RIA or ELISA... - Potential impact of human papillomavirus vaccines on public STD clinic workloads and on opportunities to diagnose and treat other sexually transmitted diseasesAmanda F Dempsey
Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109, USA
Sex Transm Dis 34:503-7. 2007..Eradicating genital warts through HPV immunization could decrease STD clinic utilization but may result in missed opportunities to diagnose other STDs... - Noninferiority of antibody response to human papillomavirus type 16 in subjects vaccinated with monovalent and quadrivalent L1 virus-like particle vaccinesSuzanne M Garland
Microbiology and Infectious Diseases Department, Royal Women s Hospital, Carlton, University of Melbourne, Melbourne, Victoria, Australia
Clin Vaccine Immunol 14:792-5. 2007.... - Quadrivalent vaccine against human papillomavirus to prevent anogenital diseasesSuzanne M Garland
Microbiology and Infectious Diseases Department, Royal Women s Hospital, and the University of Melbourne, Melbourne, Australia
N Engl J Med 356:1928-43. 2007..A phase 3 trial was conducted to evaluate the efficacy of a prophylactic quadrivalent vaccine in preventing anogenital diseases associated with human papillomavirus (HPV) types 6, 11, 16, and 18... - Efficacy of a quadrivalent prophylactic human papillomavirus (types 6, 11, 16, and 18) L1 virus-like-particle vaccine against high-grade vulval and vaginal lesions: a combined analysis of three randomised clinical trialsElmar A Joura
Department of Gynecology and Obstetrics, Medical University of Vienna, Vienna, Austria
Lancet 369:1693-702. 2007..Our aim was to do a combined analysis of three randomised clinical trials to assess the effect of a prophylactic quadrivalent HPV vaccine on the incidence of these diseases... - Immunogenicity and reactogenicity of a novel vaccine for human papillomavirus 16: a 2-year randomized controlled clinical trialGregory A Poland
Division of General Internal Medicine, Mayo Vaccine Research Group, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 80:601-10. 2005..To evaluate the immunogenicity, reactogenicity, and tolerability of a prototype human papillomavirus (HPV) 16 viruslike particle (VLP) vaccine directed against the L1 capsid protein... - Human papillomavirus through the agesRachel L Winer
J Infect Dis 191:1787-9. 2005 - Using risk factors to predict human papillomavirus infection: implications for targeted vaccination strategies in young adult womenAmanda F Dempsey
Child Health Evaluation and Research Unit, Department of Pediatrics, University of Michigan, USA
Vaccine 26:1111-7. 2008..Our results support implementation of comprehensive HPV vaccination strategies... - Human papillomavirus infection and cervical cytology in women screened for cervical cancer in the United States, 2003-2005S Deblina Datta
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Ann Intern Med 148:493-500. 2008..Millions of women in the United States receive cervical screening in sexually transmitted disease (STD), family planning, and primary care clinical settings... - Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre phase II efficacy trialLuisa L Villa
Department of Virology, Ludwig Institute for Cancer Research, Sao Paulo, Brazil
Lancet Oncol 6:271-8. 2005.... - Immunologic responses following administration of a vaccine targeting human papillomavirus Types 6, 11, 16, and 18Luisa L Villa
Department of Virology, Ludwig Institute for Cancer Research, R Prof Antonio Prudente 109, 4th Floor, 01509 010 Sao Paulo, SP, Brazil
Vaccine 24:5571-83. 2006..Following an initial, similar sized decline, anti-HPV responses plateaued and remained stable through end-of-study (3.0 years). No vaccine-related serious adverse experiences were reported... - National burden of genital warts: a first step in defining the problemAmanda F Dempsey
Sex Transm Dis 35:361-2. 2008 - Men's perceptions and knowledge of human papillomavirus (HPV) infection and cervical cancerTara S McPartland
Yale University School of Medicine, Department of Pediatrics, New Haven, Connecticut 06520, USA
J Am Coll Health 53:225-30. 2005..The authors concluded that it is important to include men in HPV education and prevention efforts, especially within the context that HPV may lead to cervical cancer in female partners...
Research Grants
- ACQUISITION & NATURAL HISTORY OF GENITAL HPV INFECTIONSLaura Koutsky; Fiscal Year: 2004..Additionally, these data will provide investigators working on HPV vaccine development with information that is needed to guide the selection of appropriate target populations, outcome measures, and immunization strategies. ..
- ETIOLOGY AND NATURAL HISTORY OF CERVICAL NEOPLASIALaura Koutsky; Fiscal Year: 2004..The overall goal of this research is development of accurate and cost-effective cervical cancer prevention strategies that will improve the health of diverse populations. ..
- RNA Analysis of HPV Viral LoadsLaura Koutsky; Fiscal Year: 2005....
- Acquisition and Natural History of Genital HPV InfectionLaura Koutsky; Fiscal Year: 2007..In summary, the long-range goal of this project is to improve the effectiveness of both vaccine-based and behavioral strategies for preventing HPV infection. ..
- Natural History of HPV Infections in MenLaura Koutsky; Fiscal Year: 2007..Our long-term goal is development of cost-effective approaches to the prevention of HPV-related cancers. ..
- ETIOLOGY AND NATURAL HISTORY OF CERVICAL NEOPLASIALaura Koutsky; Fiscal Year: 2007..Clear public health benefits will accrue from development of more accurate and less costly screening tests. ..
- Acquisition and Natural History of Genital HPV InfectionLaura Koutsky; Fiscal Year: 2009..In summary, the long-range goal of this project is to improve the effectiveness of both vaccine-based and behavioral strategies for preventing HPV infection. ..
- ACQUISITION & NATURAL HISTORY OF GENITAL HPV INFECTIONSLaura Koutsky; Fiscal Year: 1999..g., immunization, condoms, or sexual behavior change) and secondary prevention (e.g., screening and treatment) of cervical cancer and other HPV associated epithelial lesions. ..
- ETIOLOGY AND NATURAL HISTORY OF CERVICAL NEOPLASIALaura Koutsky; Fiscal Year: 1993....
- ETIOLOGY AND NATURAL HISTORY OF CERVICAL NEOPLASIALaura Koutsky; Fiscal Year: 2001..The proposed studies are intended to contribute to understanding of the pathogenesis of cervical caner and to have important public health implications for cervical cancer control. ..
- HPV Testing--Self-Collected Samples for Cervical CancerLaura Koutsky; Fiscal Year: 2003....
- Natural History of HPV Infections in MenLaura Koutsky; Fiscal Year: 2009..Our long-term goal is development of cost-effective approaches to the prevention of HPV-related cancers. ..