Michael Kotlyar

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc Effect of paroxetine on physiological response to stress and smoking
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, USA
    Psychosom Med 75:236-43. 2013
  2. pmc Effect of stress and bupropion on craving, withdrawal symptoms, and mood in smokers
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, 7 170 Weaver Densford Hall, 308 Harvard Street SE, Minneapolis, MN 55455, USA
    Nicotine Tob Res 13:492-7. 2011
  3. doi request reprint Physiological response to a speech stressor presented in a virtual reality environment
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, Minneapolis, Minnesota 55455, USA
    Psychophysiology 45:1034-7. 2008
  4. pmc Naltrexone effect on physiological and subjective response to a cold pressor task
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, 7 170 Weaver Densford Hall, 308 Harvard St SE, Minneapolis, MN 55455, United States
    Biol Psychol 77:233-6. 2008
  5. pmc Nicotine pharmacokinetics and subjective effects of three potential reduced exposure products, moist snuff and nicotine lozenge
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA
    Tob Control 16:138-42. 2007
  6. ncbi request reprint Effect of bupropion on physiological measures of stress in smokers during nicotine withdrawal
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA
    Pharmacol Biochem Behav 83:370-9. 2006
  7. ncbi request reprint Update on drug-induced depression in the elderly
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, Minneapolis, Minnesota 55455, USA
    Am J Geriatr Pharmacother 3:288-300. 2005
  8. ncbi request reprint Inhibition of CYP2D6 activity by bupropion
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455, USA
    J Clin Psychopharmacol 25:226-9. 2005
  9. ncbi request reprint Managing nicotine addiction
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota at Twin Cities, Minneapolis 55455, USA
    J Dent Educ 66:1061-73. 2002
  10. ncbi request reprint Nefazodone inhibits methylprednisolone disposition and enhances its adrenal-suppressant effect
    Michael Kotlyar
    School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    J Clin Psychopharmacol 23:652-6. 2003

Research Grants

Detail Information

Publications24

  1. pmc Effect of paroxetine on physiological response to stress and smoking
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, USA
    Psychosom Med 75:236-43. 2013
    ..Because exaggerated cardiovascular response to stress is associated with cardiovascular disease risk, this study examined paroxetine's effect on the physiological response to combining stress and smoking...
  2. pmc Effect of stress and bupropion on craving, withdrawal symptoms, and mood in smokers
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, 7 170 Weaver Densford Hall, 308 Harvard Street SE, Minneapolis, MN 55455, USA
    Nicotine Tob Res 13:492-7. 2011
    ..The purpose of this study was to determine the effect of bupropion (an agent known to increase smoking cessation rates) on the craving, withdrawal, and mood response to stressful tasks administered in a laboratory setting...
  3. doi request reprint Physiological response to a speech stressor presented in a virtual reality environment
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, Minneapolis, Minnesota 55455, USA
    Psychophysiology 45:1034-7. 2008
    ..The use of VR technology may be a viable alternative to methods currently employed in presenting stressful tasks with the potential advantage of decreased variability in the audience response to the participants' performance...
  4. pmc Naltrexone effect on physiological and subjective response to a cold pressor task
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, 7 170 Weaver Densford Hall, 308 Harvard St SE, Minneapolis, MN 55455, United States
    Biol Psychol 77:233-6. 2008
    ..No significant differences were found for other measures assessed. Further research is necessary to determine the subpopulations in which these effects are of greatest magnitude and the long term safety implications of these effects...
  5. pmc Nicotine pharmacokinetics and subjective effects of three potential reduced exposure products, moist snuff and nicotine lozenge
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA
    Tob Control 16:138-42. 2007
    ..To compare nicotine pharmacokinetics and subjective effects of three new smokeless tobacco potential reduced exposure products (PREPs; Ariva, Revel and Stonewall) with moist snuff (Copenhagen) and medicinal nicotine (Commit lozenge)...
  6. ncbi request reprint Effect of bupropion on physiological measures of stress in smokers during nicotine withdrawal
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA
    Pharmacol Biochem Behav 83:370-9. 2006
    ..This study suggests that bupropion may be maintaining physiological measures of stress during the nicotine withdrawal period...
  7. ncbi request reprint Update on drug-induced depression in the elderly
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, Minneapolis, Minnesota 55455, USA
    Am J Geriatr Pharmacother 3:288-300. 2005
    ..Depression is a common disorder in the elderly. Use of certain medications may be a potentially preventable cause of new-onset depression or worsening of established depression...
  8. ncbi request reprint Inhibition of CYP2D6 activity by bupropion
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455, USA
    J Clin Psychopharmacol 25:226-9. 2005
    ..Bupropion is therefore a potent inhibitor of CYP2D6 activity, and care should be exercised when initiating or discontinuing bupropion use in patients taking drugs metabolized by CYP2D6...
  9. ncbi request reprint Managing nicotine addiction
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota at Twin Cities, Minneapolis 55455, USA
    J Dent Educ 66:1061-73. 2002
    ..This review summarizes the characteristics of nicotine addiction, reviews the pharmacological agents currently used to treat tobacco use disorder, and describes possible approaches to treat nicotine dependence in the future...
  10. ncbi request reprint Nefazodone inhibits methylprednisolone disposition and enhances its adrenal-suppressant effect
    Michael Kotlyar
    School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    J Clin Psychopharmacol 23:652-6. 2003
    ..28 +/- 0.49 vs. 3.32 +/- 0.95 hours; P < 0.02). The duration of cortisol suppression after methylprednisolone administration was longer (> or =32 vs. 23.3 +/- 3.43 hours) during nefazodone administration...
  11. pmc Effect of oral snus and medicinal nicotine in smokers on toxicant exposure and withdrawal symptoms: a feasibility study
    Michael Kotlyar
    University of Minnesota Tobacco Use Research Center, University of Minnesota, Minneapolis, Minnesota, USA
    Cancer Epidemiol Biomarkers Prev 20:91-100. 2011
    ..Data are needed regarding how smokers interested in cessation would use these products, the levels of resultant toxicant exposure, and the feasibility of using these products as aids for tobacco cessation...
  12. ncbi request reprint Effects of paroxetine on cardiovascular response to mental stress in subjects with a history of coronary artery disease and no psychiatric diagnoses
    Michael Golding
    Psych Support Inc, Raleigh, NC, USA
    Psychopharmacology (Berl) 182:321-6. 2005
    ..Paroxetine may decrease mental stress-induced cardiovascular responses and so benefit individuals with heart disease, even those with no psychiatric illness...
  13. ncbi request reprint Reduced nicotine content cigarettes: effects on toxicant exposure, dependence and cessation
    Dorothy K Hatsukami
    University of Minnesota Transdisciplinary Tobacco Use Research Center, Minneapolis, MN 55414, USA
    Addiction 105:343-55. 2010
    ..To examine the effects of reduced nicotine cigarettes on smoking behavior, toxicant exposure, dependence and abstinence...
  14. ncbi request reprint Developing the science base for reducing tobacco harm
    Dorothy K Hatsukami
    University of Minnesota Transdisciplinary Tobacco Use Research Center, Minneapolis, MN 55414, USA
    Nicotine Tob Res 9:S537-53. 2007
    ..A description of the ongoing activities and challenges in these areas is provided, along with projected directions for the future...
  15. ncbi request reprint Effects of cigarette reduction on cardiovascular risk factors and subjective measures
    Dorothy K Hatsukami
    Transdisciplinary Tobacco Use Research Center, University of Minnesota, 2701 University Ave SE, Minneapolis, MN 55414, USA
    Chest 128:2528-37. 2005
    ..To assess the effect of continued smoking and smoking reduction on cardiovascular biomarkers (eg, WBC count, cholesterol concentrations, BP, heart rate)...
  16. ncbi request reprint D-cycloserine augmented exposure therapy for obsessive-compulsive disorder
    Matt G Kushner
    Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota 55454, USA
    Biol Psychiatry 62:835-8. 2007
    ..We predicted that DCS would accelerate obsession-related distress reduction in patients with obsessive-compulsive disorder (OCD) undergoing extinction-based exposure therapy...
  17. ncbi request reprint Effects of sustained-release bupropion among persons interested in reducing but not quitting smoking
    Dorothy K Hatsukami
    Department of Psychiatry DKH, MK, University of Minnesota at Twin Cities, Minneapolis, Minnesota 55414, USA
    Am J Med 116:151-7. 2004
    ....
  18. pmc Integration of an Internet-based medical chart into a pharmacotherapy lecture series
    Michael C Brown
    College of Pharmacy, University of Minnesota, USA
    Am J Pharm Educ 71:53. 2007
    ....
  19. ncbi request reprint Harm reduction approaches to reducing tobacco-related mortality
    Dorothy K Hatsukami
    University of Minnesota, Tobacco Use Research Center, Minneapolis, Minnesota 55414, USA
    Annu Rev Public Health 25:377-95. 2004
    ..A significant amount of independent research is needed to inform policy decisions. Regulatory authority over potential reduced exposure products is also essential...
  20. pmc Menstrual phase and depressive symptoms differences in physiological response to nicotine following acute smoking abstinence
    Sharon S Allen
    Department of Family Medicine and Community Health, Medical School, University of Minnesota, Minneapolis, MN 55414, USA
    Nicotine Tob Res 15:1091-8. 2013
    ..This randomized crossover study assessed physiological response to nicotine by menstrual phase in female smokers with and without depressive symptoms following acute smoking abstinence...
  21. ncbi request reprint Effect of selective serotonin reuptake inhibitors on cardiovascular morbidity and mortality
    Abby E Von Ruden
    College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA
    J Cardiovasc Pharmacol Ther 13:32-40. 2008
    ..Randomized controlled studies are clearly needed to definitively address this issue...
  22. ncbi request reprint Premature ejaculation associated with citalopram withdrawal
    David E Adson
    Department of Psychiatry, School of Medicine, University of Minnesota, Minneapolis, MN, USA
    Ann Pharmacother 37:1804-6. 2003
    ..To report a case of premature ejaculation occurring subsequent to citalopram discontinuation...
  23. ncbi request reprint Lack of a fluoxetine effect on prednisolone disposition and cortisol suppression
    Stanley W Carson
    Department of Pharmacotherapy, University of North Carolina at Chapel Hill, USA
    Pharmacotherapy 24:482-7. 2004
    ..To evaluate the potential effect of fluoxetine, a cytochrome P450 isoenzyme inhibitor, on prednisolone disposition and cortisol suppression...
  24. ncbi request reprint Paroxetine modulates psychological and sympathetic responses during public speaking
    Michael Golding
    J Clin Psychopharmacol 22:98-9. 2002

Research Grants2

  1. Smoking, Antidepressants and Response to Mental Stress
    Michael Kotlyar; Fiscal Year: 2007
    ..Patient-Oriented Research Career Development Award is to build upon the previous training and experience of Michael Kotlyar, PharmD, a tenure track assistant professor in Experimental and Clinical Pharmacology and Psychiatry...