Research Topics
| Michael KotlyarSummaryAffiliation: University of Minnesota Country: USA Publications
Research Grants
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Detail Information
Publications
Effect of paroxetine on physiological response to stress and smokingMichael Kotlyar
PharmD, Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, 7 170 Weaver Densford Hall, 308 Harvard St SE, Minneapolis, MN 55455
Psychosom Med 75:236-43. 2013..Further research is needed to determine the impact of these results on cardiovascular health. Trial Registration clinicaltrials.gov Identifier: NCT00218439...
Effect of stress and bupropion on craving, withdrawal symptoms, and mood in smokersMichael Kotlyar
Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, 7 170 Weaver Densford Hall, 308 Harvard Street SE, Minneapolis, MN 55455, USA
Nicotine Tob Res 13:492-7. 2011..The purpose of this study was to determine the effect of bupropion (an agent known to increase smoking cessation rates) on the craving, withdrawal, and mood response to stressful tasks administered in a laboratory setting...- Physiological response to a speech stressor presented in a virtual reality environmentMichael Kotlyar
Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, Minneapolis, Minnesota 55455, USA
Psychophysiology 45:1034-7. 2008..The use of VR technology may be a viable alternative to methods currently employed in presenting stressful tasks with the potential advantage of decreased variability in the audience response to the participants' performance... - Naltrexone effect on physiological and subjective response to a cold pressor taskMichael Kotlyar
Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, 7 170 Weaver Densford Hall, 308 Harvard St SE, Minneapolis, MN 55455, United States
Biol Psychol 77:233-6. 2008..No significant differences were found for other measures assessed. Further research is necessary to determine the subpopulations in which these effects are of greatest magnitude and the long term safety implications of these effects... - Nicotine pharmacokinetics and subjective effects of three potential reduced exposure products, moist snuff and nicotine lozengeMichael Kotlyar
Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA
Tob Control 16:138-42. 2007..To compare nicotine pharmacokinetics and subjective effects of three new smokeless tobacco potential reduced exposure products (PREPs; Ariva, Revel and Stonewall) with moist snuff (Copenhagen) and medicinal nicotine (Commit lozenge)... 
Effect of bupropion on physiological measures of stress in smokers during nicotine withdrawalMichael Kotlyar
Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA
Pharmacol Biochem Behav 83:370-9. 2006..This study suggests that bupropion may be maintaining physiological measures of stress during the nicotine withdrawal period...- Update on drug-induced depression in the elderlyMichael Kotlyar
Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, Minneapolis, Minnesota 55455, USA
Am J Geriatr Pharmacother 3:288-300. 2005..Depression is a common disorder in the elderly. Use of certain medications may be a potentially preventable cause of new-onset depression or worsening of established depression... - Inhibition of CYP2D6 activity by bupropionMichael Kotlyar
Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455, USA
J Clin Psychopharmacol 25:226-9. 2005..Bupropion is therefore a potent inhibitor of CYP2D6 activity, and care should be exercised when initiating or discontinuing bupropion use in patients taking drugs metabolized by CYP2D6... - Managing nicotine addictionMichael Kotlyar
Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota at Twin Cities, Minneapolis 55455, USA
J Dent Educ 66:1061-73. 2002..This review summarizes the characteristics of nicotine addiction, reviews the pharmacological agents currently used to treat tobacco use disorder, and describes possible approaches to treat nicotine dependence in the future... - Nefazodone inhibits methylprednisolone disposition and enhances its adrenal-suppressant effectMichael Kotlyar
School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
J Clin Psychopharmacol 23:652-6. 2003..28 +/- 0.49 vs. 3.32 +/- 0.95 hours; P < 0.02). The duration of cortisol suppression after methylprednisolone administration was longer (> or =32 vs. 23.3 +/- 3.43 hours) during nefazodone administration... - Effect of oral snus and medicinal nicotine in smokers on toxicant exposure and withdrawal symptoms: a feasibility studyMichael Kotlyar
University of Minnesota Tobacco Use Research Center, University of Minnesota, Minneapolis, Minnesota, USA
Cancer Epidemiol Biomarkers Prev 20:91-100. 2011..Data are needed regarding how smokers interested in cessation would use these products, the levels of resultant toxicant exposure, and the feasibility of using these products as aids for tobacco cessation... - Reduced nicotine content cigarettes: effects on toxicant exposure, dependence and cessationDorothy K Hatsukami
University of Minnesota Transdisciplinary Tobacco Use Research Center, Minneapolis, MN 55414, USA
Addiction 105:343-55. 2010..To examine the effects of reduced nicotine cigarettes on smoking behavior, toxicant exposure, dependence and abstinence... - Effects of paroxetine on cardiovascular response to mental stress in subjects with a history of coronary artery disease and no psychiatric diagnosesMichael Golding
Psych Support Inc, Raleigh, NC, USA
Psychopharmacology (Berl) 182:321-6. 2005..Paroxetine may decrease mental stress-induced cardiovascular responses and so benefit individuals with heart disease, even those with no psychiatric illness... - Developing the science base for reducing tobacco harmDorothy K Hatsukami
University of Minnesota Transdisciplinary Tobacco Use Research Center, Minneapolis, MN 55414, USA
Nicotine Tob Res 9:S537-53. 2007..A description of the ongoing activities and challenges in these areas is provided, along with projected directions for the future... - Effects of cigarette reduction on cardiovascular risk factors and subjective measuresDorothy K Hatsukami
Transdisciplinary Tobacco Use Research Center, University of Minnesota, 2701 University Ave SE, Minneapolis, MN 55414, USA
Chest 128:2528-37. 2005..To assess the effect of continued smoking and smoking reduction on cardiovascular biomarkers (eg, WBC count, cholesterol concentrations, BP, heart rate)... - D-cycloserine augmented exposure therapy for obsessive-compulsive disorderMatt G Kushner
Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota 55454, USA
Biol Psychiatry 62:835-8. 2007..We predicted that DCS would accelerate obsession-related distress reduction in patients with obsessive-compulsive disorder (OCD) undergoing extinction-based exposure therapy... - Effects of sustained-release bupropion among persons interested in reducing but not quitting smokingDorothy K Hatsukami
Department of Psychiatry DKH, MK, University of Minnesota at Twin Cities, Minneapolis, Minnesota 55414, USA
Am J Med 116:151-7. 2004.... - Integration of an Internet-based medical chart into a pharmacotherapy lecture seriesMichael C Brown
College of Pharmacy, University of Minnesota, USA
Am J Pharm Educ 71:53. 2007.... - Harm reduction approaches to reducing tobacco-related mortalityDorothy K Hatsukami
University of Minnesota, Tobacco Use Research Center, Minneapolis, Minnesota 55414, USA
Annu Rev Public Health 25:377-95. 2004..A significant amount of independent research is needed to inform policy decisions. Regulatory authority over potential reduced exposure products is also essential... - Menstrual phase and depressive symptoms differences in physiological response to nicotine following acute smoking abstinenceSharon S Allen
Department of Family Medicine and Community Health, Medical School, University of Minnesota, Minneapolis, MN
Nicotine Tob Res 15:1091-8. 2013..This randomized crossover study assessed physiological response to nicotine by menstrual phase in female smokers with and without depressive symptoms following acute smoking abstinence... - Effect of selective serotonin reuptake inhibitors on cardiovascular morbidity and mortalityAbby E Von Ruden
College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA
J Cardiovasc Pharmacol Ther 13:32-40. 2008..Randomized controlled studies are clearly needed to definitively address this issue... - Premature ejaculation associated with citalopram withdrawalDavid E Adson
Department of Psychiatry, School of Medicine, University of Minnesota, Minneapolis, MN, USA
Ann Pharmacother 37:1804-6. 2003..To report a case of premature ejaculation occurring subsequent to citalopram discontinuation... - Lack of a fluoxetine effect on prednisolone disposition and cortisol suppressionStanley W Carson
Department of Pharmacotherapy, University of North Carolina at Chapel Hill, USA
Pharmacotherapy 24:482-7. 2004..Prednisolone may be a useful alternative for patients who require both glucocorticoid and fluoxetine therapy... - Paroxetine modulates psychological and sympathetic responses during public speakingMichael Golding
J Clin Psychopharmacol 22:98-9. 2002
Research Grants
- Smoking, Antidepressants and Response to Mental StressMichael Kotlyar; Fiscal Year: 2007..Patient-Oriented Research Career Development Award is to build upon the previous training and experience of Michael Kotlyar, PharmD, a tenure track assistant professor in Experimental and Clinical Pharmacology and Psychiatry...