Research Topics
| R M KotloffSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Publications
Comparison of short-term functional outcomes following unilateral and bilateral lung volume reduction surgeryR M Kotloff
Department of Medicine, University of Pennsylvania Medical Center, Philadelphia 19104, USA
Chest 113:890-5. 1998..To compare short-term functional outcomes following unilateral and bilateral lung volume reduction surgery (LVRS) performed in patients with advanced emphysema...- Pulmonary complications of solid organ and hematopoietic stem cell transplantationRobert M Kotloff
Section of Advanced Lung Disease and Lung Transplantation, Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Medical Center, 838 West Gates, 3400 Spruce Street, Philadelphia, PA 19027, USA
Am J Respir Crit Care Med 170:22-48. 2004.... - Medical complications of lung transplantationR M Kotloff
Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
Eur Respir J 23:334-42. 2004..Familiarity with, and vigilance for, these problems should facilitate earlier recognition, more expeditious intervention and more favourable outcomes... - Apical perfusion fraction as a predictor of short-term functional outcome following bilateral lung volume reduction surgeryR M Kotloff
Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
Chest 120:1609-15. 2001..To examine whether relative hypoperfusion to the apical one third of the lungs as determined by lung scintigraphy predicts a favorable functional outcome following bilateral lung volume reduction surgery (LVRS)... - Bilateral versus single lung transplantation for chronic obstructive pulmonary disease: intermediate-term resultsA Pochettino
Division of Cardiothoracic Surgery and Pulmonary, University of Pennsylvania Medical Center, Philadelphia, USA
Ann Thorac Surg 70:1813-8; discussion 1818-9. 2000..There is controversy regarding the transplant procedure of choice in chronic obstructive pulmonary disease. We reviewed our intermediate-term outcomes with single lung transplantation (SLT) versus bilateral lung transplantation (BLT)... - Bronchogenic carcinoma complicating lung transplantationS M Arcasoy
Division of the Pulmonary, Allergy and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104 4283, USA
J Heart Lung Transplant 20:1044-53. 2001..Although a variety of malignancies have been reported in lung transplant recipients, a paucity of information exists regarding the incidence and clinical course of bronchogenic carcinoma in this patient population... - Characteristics and outcomes of patients with sarcoidosis listed for lung transplantationS M Arcasoy
Divisions of Pulmonary, Allergy and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, USA
Chest 120:873-80. 2001..To characterize the course of patients with advanced sarcoidosis who have been listed for lung transplantation and to identify prognostic factors for death while they are on the waiting list... - Reduction in immunosuppression as initial therapy for posttransplant lymphoproliferative disorder: analysis of prognostic variables and long-term follow-up of 42 adult patientsD E Tsai
Hematologic Malignancies Program, University of Pennsylvania Cancer Center, Philadelphia 19104, USA
Transplantation 71:1076-88. 2001..With the increased use of organ transplantation and intensive immunosuppression, this disease is becoming more common. We explore reduction in immunosuppression as an initial therapy for PTLD... 
Risk factors for early primary graft dysfunction after lung transplantation: a registry studyCatherine L Kuntz
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Clin Transplant 23:819-30. 2009..We sought to identify risk factors for PGD using the United Network for Organ Sharing/International Society for Heart and Lung Transplant (UNOS/ISHLT) Registry...- Association of clinical risk factors with functional status following lung transplantationJ S Sager
Pulmonary, Allergy and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
Am J Transplant 6:2191-201. 2006..51). These findings may have implications in patient counseling, selection, procedure choice, and may lead to interventions aimed at improving the functional outcomes of lung transplantation... - Utility of high resolution computed tomography in predicting bronchiolitis obliterans syndrome following lung transplantation: preliminary findingsW T Miller
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, USA
J Thorac Imaging 16:76-80. 2001..No high resolution CT features accurately predicted the development of BOS... - Does lung transplantation confer a survival benefit?Robert M Kotloff
Section of Advanced Lung Disease and Lung Transplantation, Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
Curr Opin Organ Transplant 14:499-503. 2009..This article reviews the current literature addressing the question of whether transplantation is truly a life-extending procedure... - Association between elevated whole blood Epstein-Barr virus (EBV)-encoded RNA EBV polymerase chain reaction and reduced incidence of acute lung allograft rejectionVivek N Ahya
Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
J Heart Lung Transplant 26:839-44. 2007..We investigated the hypothesis that detection of latent Epstein-Barr virus (EBV) in peripheral blood may be a functional marker for the net effects of administered immunosuppression... - Low prevalence of prior streptococcus pneumoniae vaccination among potential lung transplant candidatesLeanne B Gasink
Division of Infectious Diseases, Department of Medicine, 502 Johnson Pavillion, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Chest 130:218-21. 2006..Appropriate vaccination status in the pre-solid organ transplant period is critically important... - Noninfectious pulmonary complications of liver, heart, and kidney transplantationRobert M Kotloff
Section of Advanced Lung Disease and Lung Transplantation, Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
Clin Chest Med 26:623-9, vii. 2005..This article focuses on noninfectious pulmonary complications in the three largest recipient populations: liver, kidney, and heart... 
Plasma levels of receptor for advanced glycation end products, blood transfusion, and risk of primary graft dysfunctionJason D Christie
Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Am J Respir Crit Care Med 180:1010-5. 2009..We hypothesized that patients with primary graft dysfunction (PGD) after lung transplantation would have higher RAGE levels in plasma than patients without PGD...- Serum protein electrophoresis abnormalities in adult solid organ transplant patients with post-transplant lymphoproliferative disorderDonald E Tsai
Hematologic Malignancies Program, University of Pennsylvania Cancer Center, Philadelphia, PA 19104, USA
Clin Transplant 19:644-52. 2005..68 wk, p = 0.003). Persistence of MG after complete response of the PTLD did not predict relapse. There is a high incidence of MG and gammaglobulin abnormalities in patients with PTLD... - Renal and vestibular toxicity due to inhaled tobramycin in a lung transplant recipientVivek N Ahya
Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
J Heart Lung Transplant 24:932-5. 2005..We review the literature regarding the safety of inhaled tobramycin and discuss potential mechanisms that may promote systemic toxicity in transplant recipients... - The effect of primary graft dysfunction on survival after lung transplantationJason D Christie
Division of Pulmonary, Allergy, and Critical Care Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 423 Guardian Drive, 719 Blockley Hall, Philadelphia, PA 19104, USA
Am J Respir Crit Care Med 171:1312-6. 2005..Primary graft dysfunction is a severe acute lung injury syndrome after lung transplantation. Long-term outcomes of subjects with primary graft dysfunction have not been studied... - Impact of primary graft failure on outcomes following lung transplantationJason D Christie
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Chest 127:161-5. 2005..Primary graft failure (PGF) is a severe acute lung injury syndrome that occurs following lung transplantation. We compared the clinical outcomes of patients who developed PGF with those who did not... - CD3 monitoring of antithymocyte globulin therapy in thoracic organ transplantationAlyssa M Krasinskas
Department of Pathology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104-4283, USA
Transplantation 73:1339-41. 2002..CONCLUSION: CD3 monitoring of antithymocyte globulin therapy in thoracic organ recipients reduced the amount of drug received by each patient, while maintaining CD3 counts less than 100 cells/microl... - Recurrent spontaneous pneumothorax in a patient with Birt-Hogg-Dubé syndromeJarrod D Predina
Division of Thoracic Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Eur J Cardiothorac Surg 39:404-6. 2011..This case is of particular interest to the cardiothoracic surgery community as the patient described as well as several of his family members were managed by multiple thoracic surgeons, who did not appreciate the diagnosis... - Use of EBV PCR for the diagnosis and monitoring of post-transplant lymphoproliferative disorder in adult solid organ transplant patientsDonald E Tsai
Hematologic Malignancies Program, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania 19104, USA
Am J Transplant 2:946-54. 2002..We conclude that peripheral blood EBV PCR may have a role in the diagnosis and monitoring of post-transplant lymphoproliferative disorder in adult solid organ transplant patients... - Clinical risk factors for primary graft failure following lung transplantationJason D Christie
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelhia, 19104, USA
Chest 124:1232-41. 2003..s: Primary graft failure (PGF) is a devastating acute lung injury syndrome following lung transplantation. We sought to identify donor, recipient, and operative risk factors for its development... - Emergent lung retransplantation after discovery of two primary malignancies in the donorD Kreisel
Division of Cardiothoracic Surgery, Department of Surgery, University of Pennsylvania Medical Center, 3400 Spruce, Philadelphia, PA 19104, USA
Transplantation 71:1859-62. 2001..After 24 months, the patient is without evidence of malignancy. This case illustrates the role of immediate retransplantation for patients who have inadvertently received thoracic organs from donors harboring occult malignancies... - Risk factors for death of patients with cystic fibrosis awaiting lung transplantationRichard A Belkin
Division of Pulmonary, Allergy, and Critical Care, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Medical Center, Philadelphia, PA, USA
Am J Respir Crit Care Med 173:659-66. 2006..The optimal timing for listing of cystic fibrosis patients for lung transplantation is controversial... - Lung transplant outcomes in white and African American recipients: special focus on acute and chronic rejectionRajiv Lingaraju
Division of Pulmonary Critical Care, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Heart Lung Transplant 28:8-13. 2009.... - Effects of lung allocation score on waiting list rankings and transplant proceduresRajiv Lingaraju
Division of Pulmonary/Critical Care, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Heart Lung Transplant 25:1167-70. 2006.... - Association between pulmonary fibrosis and coronary artery diseaseJorge R Kizer
Division of Cardiology, Department of Medicine, Weill Medical College of Cornell University, New York, NY, USA
Arch Intern Med 164:551-6. 2004..Further research is necessary to confirm this relationship and to explore the pathologic processes underlying, and potentially linking, these 2 conditions... - Lung transplantation for chronic obstructive pulmonary disease: special considerationsJoshua Diamond
Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
Semin Respir Crit Care Med 31:115-22. 2010..Those undergoing SLT are uniquely at risk for complications related to the remaining native lung-bronchogenic carcinoma and progressive hyperinflation-which are fortunately rare... - Cardiopulmonary bypass for bilateral sequential lung transplantation in patients with chronic obstructive pulmonary disease without adverse effect on lung function or clinical outcomeWilson Y Szeto
Department of Surgery, Division of Cardiothoracic Surgery, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
J Thorac Cardiovasc Surg 124:241-9. 2002..We hope that this pilot study removes some of the unwarranted fear of the use of bypass in lung transplantation for chronic obstructive pulmonary disease... - An overview of solid organ transplantationRoy D Bloom
Renal, Electrolyte, and Hypertension Division, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
Clin Chest Med 26:529-43, v. 2005..This article offers an overview of the various solid organ transplant procedures to provide a context within which subsequent articles on pulmonary complications can be viewed... - Pro/Con debate: lung allocation should be based on medical urgency and transplant survival and not on waiting timeThomas M Egan
University of Pennsylvania Medical Center, 838 West Gates, 3400 Spruce Street, Philadelphia, PA 19027, USA
Chest 128:407-15. 2005 - Central airways obstruction due to Aspergillus fumigatus after lung transplantationElizabeth Cerceo
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Heart Lung Transplant 28:515-9. 2009..All 3 patients presented with atypical features of Aspergillus infection, but all responded to treatments with either steroids, anti-fungals or both... - Severe venous and lymphatic obstruction after single-chamber pacemaker implantation in a patient with chest radiation therapyJoshua M Diamond
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA
Pacing Clin Electrophysiol 33:520-4. 2010..pace 2010; 520-524)... - Selection of candidates for lung transplantationMaryl Kreider
Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
Proc Am Thorac Soc 6:20-7. 2009..It will highlight current guidelines put forth by the International Society of Heart and Lung Transplantation and will explore the published data upon which these guidelines are based... - Echocardiographic assessment of pulmonary hypertension in patients with advanced lung diseaseSelim M Arcasoy
Division of Pulmonary, Allergy and Critical Care, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Am J Respir Crit Care Med 167:735-40. 2003.... - Lung retransplantation: all for one or one for all?Robert M Kotloff
Chest 123:1781-2. 2003 - Update in transplantation 2005Marc Estenne
Chest Service, Erasme University Hospital, 808 Route de Lennik, B-1070 Brussels, Belgium
Am J Respir Crit Care Med 173:593-8. 2006