MALAK YS KOTB

Summary

Affiliation: University of Tennessee
Country: USA

Publications

  1. ncbi request reprint An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections
    Malak Kotb
    Veterans Affairs Medical Center, Research Service, Memphis, Tennessee, USA
    Nat Med 8:1398-404. 2002
  2. pmc An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis
    Nourtan F Abdeltawab
    Mid South Center for Biodefense and Security, The University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
    PLoS Pathog 4:e1000042. 2008
  3. ncbi request reprint Association of human leukocyte antigen with outcomes of infectious diseases: the streptococcal experience
    M Kotb
    Veterans Affairs Medical Center, Research Service, Memphis, Tennessee 38163, USA
    Scand J Infect Dis 35:665-9. 2003
  4. ncbi request reprint Human islet graft function in NOD-SCID mice predicts clinical response in islet transplant recipients
    A O Gaber
    Department of Surgery, University of Tennessee, Memphis, 38103, USA
    Transplant Proc 36:1108-10. 2004
  5. ncbi request reprint Host variation in cytokine responses to superantigens determine the severity of invasive group A streptococcal infection
    A Norrby-Teglund
    Veterans Affairs Medical Center, Research Service, Memphis, TN, USA
    Eur J Immunol 30:3247-55. 2000
  6. pmc Reciprocal, temporal expression of SpeA and SpeB by invasive M1T1 group a streptococcal isolates in vivo
    S U Kazmi
    Research Service, Veterans Affairs Medical Center, Memphis, Tennessee 38104, USA
    Infect Immun 69:4988-95. 2001

Collaborators

Detail Information

Publications6

  1. ncbi request reprint An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections
    Malak Kotb
    Veterans Affairs Medical Center, Research Service, Memphis, Tennessee, USA
    Nat Med 8:1398-404. 2002
    ..We propose that human leukocyte antigen class II allelic variation contributes to differences in severity of invasive streptococcal infections through their ability to regulate cytokine responses triggered by streptococcal superantigens...
  2. pmc An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis
    Nourtan F Abdeltawab
    Mid South Center for Biodefense and Security, The University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
    PLoS Pathog 4:e1000042. 2008
    ..The association of GAS sepsis with multiple pathways underscores the complexity of traits modulating GAS sepsis and provides a powerful approach for analyzing interactive traits affecting outcomes of other infectious diseases...
  3. ncbi request reprint Association of human leukocyte antigen with outcomes of infectious diseases: the streptococcal experience
    M Kotb
    Veterans Affairs Medical Center, Research Service, Memphis, Tennessee 38163, USA
    Scand J Infect Dis 35:665-9. 2003
    ....
  4. ncbi request reprint Human islet graft function in NOD-SCID mice predicts clinical response in islet transplant recipients
    A O Gaber
    Department of Surgery, University of Tennessee, Memphis, 38103, USA
    Transplant Proc 36:1108-10. 2004
    ..8 ng/mL and insulin free until suffering a rejection episode 3 months later. We observed that human islet graft function in NOD-SCID mice correlated with clinical response in islet transplant recipients...
  5. ncbi request reprint Host variation in cytokine responses to superantigens determine the severity of invasive group A streptococcal infection
    A Norrby-Teglund
    Veterans Affairs Medical Center, Research Service, Memphis, TN, USA
    Eur J Immunol 30:3247-55. 2000
    ..We therefore conclude that host factors influence the magnitude of cytokine responses to superantigens and consequently the clinical outcome of the infection...
  6. pmc Reciprocal, temporal expression of SpeA and SpeB by invasive M1T1 group a streptococcal isolates in vivo
    S U Kazmi
    Research Service, Veterans Affairs Medical Center, Memphis, Tennessee 38104, USA
    Infect Immun 69:4988-95. 2001
    ..This underscores the role of the host-pathogen interaction in regulating the expression of streptococcal virulence factors in vivo. The model described here should facilitate such studies...