Maranke I Koster

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi request reprint Epidermal differentiation: transgenic/knockout mouse models reveal genes involved in stem cell fate decisions and commitment to differentiation
    Maranke I Koster
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Investig Dermatol Symp Proc 7:41-5. 2002
  2. pmc Sorting out the p63 signaling network
    Maranke I Koster
    Department of Dermatology and Charles C Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado Denver, Aurora, Colorado 80045, USA
    J Invest Dermatol 128:1617-9. 2008
  3. ncbi request reprint Mechanisms regulating epithelial stratification
    Maranke I Koster
    Department of Dermatology and Charles C Gates Program in Regenerative Medicine and Stem Cell Biology, University of Colorado at Denver and Health Sciences Center, Aurora, CO 80010, USA
    Annu Rev Cell Dev Biol 23:93-113. 2007
  4. pmc DeltaNp63 knockdown mice: A mouse model for AEC syndrome
    Maranke I Koster
    Department of Dermatology and Charles C Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado Denver, Aurora, CO 80045, USA
    Am J Med Genet A 149:1942-7. 2009
  5. pmc p63 in skin development and ectodermal dysplasias
    Maranke I Koster
    Department of Dermatology, Charles C Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado Denver, Aurora, Colorado 80045, USA
    J Invest Dermatol 130:2352-8. 2010
  6. pmc Making an epidermis
    Maranke I Koster
    Department of Dermatology and Charles C Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado Denver, Aurora, Colorado 80045, USA
    Ann N Y Acad Sci 1170:7-10. 2009
  7. pmc Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation
    Bach Cuc Nguyen
    Cutaneous Biology Research Center, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA, and Department of Biochemistry, University of Lausanne, Switzerland
    Genes Dev 20:1028-42. 2006
  8. ncbi request reprint Conflicting roles for p63 in skin development and carcinogenesis
    Maranke I Koster
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Cell Cycle 6:269-73. 2007
  9. pmc p63 induces key target genes required for epidermal morphogenesis
    Maranke I Koster
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 104:3255-60. 2007
  10. ncbi request reprint P63 deficiency: a failure of lineage commitment or stem cell maintenance?
    Maranke I Koster
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Investig Dermatol Symp Proc 10:118-23. 2005

Collaborators

  • Piranit N Kantaputra
  • A A Mills
  • Aimee S Payne
  • Dennis R Roop
  • Jillian Guttormsen
  • Viraj R Shah
  • Bach Cuc Nguyen
  • William M Keyes
  • Kimberly A Honeycutt
  • Allen G Li
  • Quinton A Winger
  • John R Stevens
  • Trevor Williams
  • Lei Wei
  • Qi Li
  • David M Spencer
  • Robert J Schwartz
  • Jiang Chang
  • Alice Tommasi di Vignano
  • Xuecui Guo
  • Zhuo Zhang
  • Vikram Devgan
  • Yi Qi
  • Dario Antonini
  • Kristin M Petherbridge
  • Caterina Missero
  • Jian Wang
  • Allan Bradley
  • Karine Lefort
  • Hannes Vogel
  • Anna Mandinova
  • G Paolo Dotto
  • Giovanna Chiorino
  • Giusy Della Gatta
  • Jan Kitajewski
  • Xiao Jing Wang

Detail Information

Publications23

  1. ncbi request reprint Epidermal differentiation: transgenic/knockout mouse models reveal genes involved in stem cell fate decisions and commitment to differentiation
    Maranke I Koster
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Investig Dermatol Symp Proc 7:41-5. 2002
    ..In this review, we discuss transgenic/knockout mouse models that have provided evidence linking c-Myc and p63 to different stages of epidermal development and differentiation...
  2. pmc Sorting out the p63 signaling network
    Maranke I Koster
    Department of Dermatology and Charles C Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado Denver, Aurora, Colorado 80045, USA
    J Invest Dermatol 128:1617-9. 2008
    ..In this issue, Antonini et al., describe a novel p63 target gene whose evolutionary conservation suggests a critical role for this gene in the epidermis...
  3. ncbi request reprint Mechanisms regulating epithelial stratification
    Maranke I Koster
    Department of Dermatology and Charles C Gates Program in Regenerative Medicine and Stem Cell Biology, University of Colorado at Denver and Health Sciences Center, Aurora, CO 80010, USA
    Annu Rev Cell Dev Biol 23:93-113. 2007
    ..In this review we summarize the current advances that have been made in understanding the molecular mechanisms that regulate epidermal morphogenesis...
  4. pmc DeltaNp63 knockdown mice: A mouse model for AEC syndrome
    Maranke I Koster
    Department of Dermatology and Charles C Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado Denver, Aurora, CO 80045, USA
    Am J Med Genet A 149:1942-7. 2009
    ..c) 2009 Wiley-Liss, Inc...
  5. pmc p63 in skin development and ectodermal dysplasias
    Maranke I Koster
    Department of Dermatology, Charles C Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado Denver, Aurora, Colorado 80045, USA
    J Invest Dermatol 130:2352-8. 2010
    ..This review summarizes the current understanding of the role of p63 in normal development and ectodermal dysplasias...
  6. pmc Making an epidermis
    Maranke I Koster
    Department of Dermatology and Charles C Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado Denver, Aurora, Colorado 80045, USA
    Ann N Y Acad Sci 1170:7-10. 2009
    ..This review summarizes our current understanding of the mechanisms that control proliferation and differentiation of epidermal stem cells, and thus addresses fundamental processes that control epidermal morphogenesis and function...
  7. pmc Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation
    Bach Cuc Nguyen
    Cutaneous Biology Research Center, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA, and Department of Biochemistry, University of Lausanne, Switzerland
    Genes Dev 20:1028-42. 2006
    ..Thus, a complex cross-talk between Notch and p63 is involved in the balance between keratinocyte self-renewal and differentiation...
  8. ncbi request reprint Conflicting roles for p63 in skin development and carcinogenesis
    Maranke I Koster
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Cell Cycle 6:269-73. 2007
    ..In this review, we discuss these conflicting findings and provide evidence for various roles of p63 in the epidermis under normal and pathological conditions...
  9. pmc p63 induces key target genes required for epidermal morphogenesis
    Maranke I Koster
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 104:3255-60. 2007
    ..Our data provide insights into the role of DeltaNp63alpha in epidermal morphogenesis and homeostasis, and may contribute to our understanding of the pathogenic mechanisms underlying disorders caused by p63 mutations...
  10. ncbi request reprint P63 deficiency: a failure of lineage commitment or stem cell maintenance?
    Maranke I Koster
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Investig Dermatol Symp Proc 10:118-23. 2005
    ..In this review, we discuss evidence suggesting that p63 is required for the commitment to stratification, making p63 the earliest known gene expressed in the developing epidermis that is specific for the keratinocyte lineage...
  11. pmc p63 is the molecular switch for initiation of an epithelial stratification program
    Maranke I Koster
    Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Genes Dev 18:126-31. 2004
    ..Our data demonstrate that p63 plays a dual role: initiating epithelial stratification during development and maintaining proliferative potential of basal keratinocytes in mature epidermis...
  12. ncbi request reprint The role of p63 in development and differentiation of the epidermis
    Maranke I Koster
    Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Dermatol Sci 34:3-9. 2004
    ..In this review, we discuss recent evidence supporting this dual role for p63 and place it in the context of our increasing knowledge of epidermal development and differentiation...
  13. ncbi request reprint p63 and epithelial appendage development
    Maranke I Koster
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Differentiation 72:364-70. 2004
    ..In this review, we will discuss the current knowledge of the developmental role of p63 and the implications for epithelial appendage development...
  14. ncbi request reprint Genes involved in stem cell fate decisions and commitment to differentiation play a role in skin disease
    Kimberly A Honeycutt
    Departments of Molecular and Cellular Biology, Houston, Texas 77030, USA
    J Investig Dermatol Symp Proc 9:261-8. 2004
    ..In this review, we will discuss recent data implicating a role for both c-Myc and p63 in human skin diseases...
  15. ncbi request reprint Transgenic mouse models provide new insights into the role of p63 in epidermal development
    Maranke I Koster
    Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Cell Cycle 3:411-3. 2004
    ..These data demonstrate that TA- and DeltaNp63 isoforms have fundamentally different roles during epidermal development and provide new insight into the molecular events required for normal epidermal morphogenesis...
  16. ncbi request reprint TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis
    Maranke I Koster
    Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Dev Biol 289:253-61. 2006
    ..Our data identify AP-2gamma as the first in vivo target gene of TAp63alpha, and provide novel insights into the molecular mechanisms associated with early events in epidermal morphogenesis...
  17. ncbi request reprint Roles of TGFbeta signaling in epidermal/appendage development
    Allen G Li
    Department of Dermatology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Cytokine Growth Factor Rev 14:99-111. 2003
    ..Future studies will be instrumental in defining the precise roles for TGFbeta superfamily signaling in epidermal/appendage development...
  18. pmc Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice
    Jillian Guttormsen
    Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA
    Dev Biol 317:187-95. 2008
    ..These results document an important role for AP-2 gamma in skin development, and reveal the existence of regulatory factors that can compensate for AP-2 gamma in its absence...
  19. pmc Double-inducible gene activation system for caspase 3 and 9 in epidermis
    Viraj R Shah
    Center for Molecular Development and Disease, Texas A and M University Health Science Center, Institute of Biosciences and Technology, Houston, Texas 77030, USA
    Genesis 45:194-9. 2007
    ..This Double-Inducible Gene Activation System generates two barriers for the target gene expression and protein activation thereby minimizing leakage...
  20. pmc p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors
    William M Keyes
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    Proc Natl Acad Sci U S A 103:8435-40. 2006
    ..These findings demonstrate that, in agreement with data from human tumors, p63 plays a markedly different biological role in cancer than p53...
  21. ncbi request reprint Genetic pathways required for epidermal morphogenesis
    Maranke I Koster
    Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Eur J Cell Biol 83:625-9. 2004
    ..In this review, we summarize the involvement of several signaling pathways in different stages of epidermal morphogenesis...
  22. ncbi request reprint Asymmetric cell division in skin development: a new look at an old observation
    Maranke I Koster
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Dev Cell 9:444-6. 2005
    ..A recent article by Lechler and Fuchs in Nature (Lechler and Fuchs, 2005) suggests that these events are triggered by asymmetric cell division...
  23. ncbi request reprint Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression
    Maranke I Koster
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Cancer Res 66:3981-6. 2006
    ..Thus, as observed for other developmental pathways, aberrant reactivation of TAp63 predisposes to tumor development and progression...