Phillip G Kopf

Summary

Affiliation: University of New Mexico
Country: USA

Publications

  1. pmc In utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effects on fetal and adult cardiac gene expression and adult cardiac and renal morphology
    Andrea C Aragon
    College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA
    Toxicol Sci 101:321-30. 2008
  2. pmc Hypertension, cardiac hypertrophy, and impaired vascular relaxation induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin are associated with increased superoxide
    Phillip G Kopf
    College of Pharmacy, University of New Mexico Health Sciences Center, MSC09 5360, 2502 Marble NE, Albuquerque, NM 87131, USA
    Cardiovasc Toxicol 8:181-93. 2008
  3. doi request reprint Overview of developmental heart defects by dioxins, PCBs, and pesticides
    Phillip G Kopf
    University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 27:276-85. 2009
  4. pmc Cytochrome P4501A1 is required for vascular dysfunction and hypertension induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    Phillip G Kopf
    Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131, USA
    Toxicol Sci 117:537-46. 2010

Collaborators

Detail Information

Publications4

  1. pmc In utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effects on fetal and adult cardiac gene expression and adult cardiac and renal morphology
    Andrea C Aragon
    College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA
    Toxicol Sci 101:321-30. 2008
    ..These results demonstrate that in utero and lactational TCDD exposures alter cardiac gene expression and cardiac and renal morphology in adulthood, which may increase the susceptibility to cardiovascular dysfunction...
  2. pmc Hypertension, cardiac hypertrophy, and impaired vascular relaxation induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin are associated with increased superoxide
    Phillip G Kopf
    College of Pharmacy, University of New Mexico Health Sciences Center, MSC09 5360, 2502 Marble NE, Albuquerque, NM 87131, USA
    Cardiovasc Toxicol 8:181-93. 2008
    ..Our model is the first to definitely demonstrate that sustained AhR activation by TCDD increases blood pressure and induces cardiac hypertrophy, which may be mediated, in part, by increased superoxide...
  3. doi request reprint Overview of developmental heart defects by dioxins, PCBs, and pesticides
    Phillip G Kopf
    University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 27:276-85. 2009
    ..However, recent animal research has confirmed human epidemiology studies that dioxin exposure in adulthood is associated with hypertension and cardiovascular disease...
  4. pmc Cytochrome P4501A1 is required for vascular dysfunction and hypertension induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    Phillip G Kopf
    Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131, USA
    Toxicol Sci 117:537-46. 2010
    ..These results demonstrate that CYP1A1 is required for TCDD-induced cardiovascular superoxide anion production, endothelial dysfunction, and hypertension...