Satoshi Komatsu

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. pmc Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes
    Satoshi Komatsu
    Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Cell Physiol 227:3201-7. 2012
  2. pmc The phosphorylation of myosin II at the Ser1 and Ser2 is critical for normal platelet-derived growth factor induced reorganization of myosin filaments
    Satoshi Komatsu
    Department of Physiology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Mol Biol Cell 18:5081-90. 2007
  3. ncbi request reprint Protein kinase Cepsilon and the antiadrenergic action of adenosine in rat ventricular myocytes
    Koji Miyazaki
    Dept of Physiology, S4 242, University of Massachusetts Medical School, 55 Lake Avenue N, Worcester, MA 01655, USA
    Am J Physiol Heart Circ Physiol 287:H1721-9. 2004
  4. pmc Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-epsilon to RACK2 in adult rat and mouse
    Richard A Fenton
    Department of Physiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Physiol Heart Circ Physiol 297:H718-25. 2009
  5. pmc Novel ZIP kinase isoform lacks leucine zipper
    Norio Takamoto
    Department of Physiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Arch Biochem Biophys 456:194-203. 2006
  6. ncbi request reprint Dynamics of RhoA and ROKalpha translocation in single living cells
    Koji Miyazaki
    Department of Physiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Cell Biochem Biophys 45:243-54. 2006
  7. pmc ZIP kinase is responsible for the phosphorylation of myosin II and necessary for cell motility in mammalian fibroblasts
    Satoshi Komatsu
    Dept of Physiology, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
    J Cell Biol 165:243-54. 2004
  8. pmc Head-head and head-tail interaction: a general mechanism for switching off myosin II activity in cells
    Hyun Suk Jung
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Mol Biol Cell 19:3234-42. 2008
  9. pmc ZIPK is critical for the motility and contractility of VSMCs through the regulation of nonmuscle myosin II isoforms
    Satoshi Komatsu
    Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts
    Am J Physiol Heart Circ Physiol 306:H1275-86. 2014
  10. ncbi request reprint Translocation of telokin by cGMP signaling in smooth muscle cells
    Satoshi Komatsu
    Department of Physiology, University of Massachusetts Medical School, Worcester 01655, USA
    Am J Physiol Cell Physiol 283:C752-61. 2002

Collaborators

Detail Information

Publications10

  1. pmc Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes
    Satoshi Komatsu
    Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Cell Physiol 227:3201-7. 2012
    ..In that this translocation has been previously associated with the antiadrenergic property of A(1)R, it is apparent that the interactive effects of adenosine and β(1)-adrenergic agonists on function are complex in the heart...
  2. pmc The phosphorylation of myosin II at the Ser1 and Ser2 is critical for normal platelet-derived growth factor induced reorganization of myosin filaments
    Satoshi Komatsu
    Department of Physiology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Mol Biol Cell 18:5081-90. 2007
    ....
  3. ncbi request reprint Protein kinase Cepsilon and the antiadrenergic action of adenosine in rat ventricular myocytes
    Koji Miyazaki
    Dept of Physiology, S4 242, University of Massachusetts Medical School, 55 Lake Avenue N, Worcester, MA 01655, USA
    Am J Physiol Heart Circ Physiol 287:H1721-9. 2004
    ..These results suggest that the translocation of PKCepsilon to the t-tubular system plays an important role in A(1)R-mediated antiadrenergic actions in the heart...
  4. pmc Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-epsilon to RACK2 in adult rat and mouse
    Richard A Fenton
    Department of Physiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Physiol Heart Circ Physiol 297:H718-25. 2009
    ..In conclusion, A(1)R stimulation of the heart is associated with PLC-initiated PKC-epsilon translocation and association with RACK2...
  5. pmc Novel ZIP kinase isoform lacks leucine zipper
    Norio Takamoto
    Department of Physiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Arch Biochem Biophys 456:194-203. 2006
    ..These results suggest that the newly found hZIPK-S as well as the long isoform play an important role in the regulation of myosin phosphorylation...
  6. ncbi request reprint Dynamics of RhoA and ROKalpha translocation in single living cells
    Koji Miyazaki
    Department of Physiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Cell Biochem Biophys 45:243-54. 2006
    ....
  7. pmc ZIP kinase is responsible for the phosphorylation of myosin II and necessary for cell motility in mammalian fibroblasts
    Satoshi Komatsu
    Dept of Physiology, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
    J Cell Biol 165:243-54. 2004
    ..These results suggest that ZIP kinase is critical for myosin phosphorylation and necessary for cell motile processes in mammalian fibroblasts...
  8. pmc Head-head and head-tail interaction: a general mechanism for switching off myosin II activity in cells
    Hyun Suk Jung
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Mol Biol Cell 19:3234-42. 2008
    ..These interactions are broken when myosin is activated...
  9. pmc ZIPK is critical for the motility and contractility of VSMCs through the regulation of nonmuscle myosin II isoforms
    Satoshi Komatsu
    Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts
    Am J Physiol Heart Circ Physiol 306:H1275-86. 2014
    ..These results suggest that NMIIA and NMIIB uniquely control VSMC migration and may contribute to vascular remodeling, which are both regulated by zipper-interacting protein kinase. ..
  10. ncbi request reprint Translocation of telokin by cGMP signaling in smooth muscle cells
    Satoshi Komatsu
    Department of Physiology, University of Massachusetts Medical School, Worcester 01655, USA
    Am J Physiol Cell Physiol 283:C752-61. 2002
    ..These results suggest that telokin changes its intracellular localization because of phosphorylation at Ser13 and/or Ser19 via the cGMP-signaling pathway...