Andras Komaromy

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Hypertensive retinopathy and choroidopathy in a cat
    Andras M Komaromy
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 0126, USA
    Vet Ophthalmol 7:3-9. 2004
  2. ncbi Periocular sarcoid in a horse
    Andras M Komaromy
    Department of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 0126, USA
    Vet Ophthalmol 7:141-6. 2004
  3. ncbi Application of a new subretinal injection device in the dog
    Andras M Komaromy
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Cell Transplant 15:511-9. 2006
  4. ncbi Targeting gene expression to cones with human cone opsin promoters in recombinant AAV
    A M Komaromy
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Gene Ther 15:1049-55. 2008
  5. ncbi Operating in the dark: a night-vision system for surgery in retinas susceptible to light damage
    Andras M Komaromy
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey St, Philadelphia, PA 19104, USA
    Arch Ophthalmol 126:714-7. 2008
  6. ncbi Gene therapy rescues cone function in congenital achromatopsia
    Andras M Komaromy
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Hum Mol Genet 19:2581-93. 2010
  7. ncbi Equine Multiple Congenital Ocular Anomalies (MCOA) syndrome in PMEL17 (Silver) mutant ponies: five cases
    Andras M Komaromy
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Vet Ophthalmol 14:313-20. 2011
  8. ncbi Exclusion of RPGRIP1 ins44 from primary causal association with early-onset cone-rod dystrophy in dogs
    Tatyana Kuznetsova
    Section of Ophthalmology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Invest Ophthalmol Vis Sci 53:5486-501. 2012
  9. ncbi Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer
    Jeannette Bennicelli
    Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6069, USA
    Mol Ther 16:458-65. 2008

Research Grants

  1. Achromatopsia - Disease Mechanisms and Cone-Directed Gene Therapy
    Andras Komaromy; Fiscal Year: 2010
  2. Achromatopsia - Disease Mechanisms and Cone-Directed Gene Therapy
    Andras Komaromy; Fiscal Year: 2010

Collaborators

Detail Information

Publications9

  1. ncbi Hypertensive retinopathy and choroidopathy in a cat
    Andras M Komaromy
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 0126, USA
    Vet Ophthalmol 7:3-9. 2004
    ..The cat subsequently regained vision. The improvement in retinal function was documented using electroretinography...
  2. ncbi Periocular sarcoid in a horse
    Andras M Komaromy
    Department of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 0126, USA
    Vet Ophthalmol 7:141-6. 2004
    ..In total, five injections were performed at 2-week intervals. At follow-up 7 months after the last BCG injection, the tumor was completely resolved. Two years after the last treatment, the horse remains tumor-free...
  3. ncbi Application of a new subretinal injection device in the dog
    Andras M Komaromy
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Cell Transplant 15:511-9. 2006
    ..In summary, the use of the RetinaJect can be recommended as an alternative to the CSID for subretinal injections in dogs...
  4. ncbi Targeting gene expression to cones with human cone opsin promoters in recombinant AAV
    A M Komaromy
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Gene Ther 15:1049-55. 2008
    ..These results suggest that L/M cones, the predominant class of cone photoreceptors in the retinas of dogs and most mammalian species can be successfully targeted using the human red cone opsin promoter...
  5. ncbi Operating in the dark: a night-vision system for surgery in retinas susceptible to light damage
    Andras M Komaromy
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey St, Philadelphia, PA 19104, USA
    Arch Ophthalmol 126:714-7. 2008
    ....
  6. ncbi Gene therapy rescues cone function in congenital achromatopsia
    Andras M Komaromy
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Hum Mol Genet 19:2581-93. 2010
    ..Our results hold promise for future clinical trials of cone-directed gene therapy in achromatopsia and other cone-specific disorders...
  7. ncbi Equine Multiple Congenital Ocular Anomalies (MCOA) syndrome in PMEL17 (Silver) mutant ponies: five cases
    Andras M Komaromy
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Vet Ophthalmol 14:313-20. 2011
    ..To describe the clinical phenotype and genetics of equine Multiple Congenital Ocular Anomalies (MCOA) syndrome in PMEL17 (Silver) mutant ponies...
  8. ncbi Exclusion of RPGRIP1 ins44 from primary causal association with early-onset cone-rod dystrophy in dogs
    Tatyana Kuznetsova
    Section of Ophthalmology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Invest Ophthalmol Vis Sci 53:5486-501. 2012
    ..However, from the recent identification of a significant discordance in genotype-phenotype association, we have reexamined the role of cRPGRIP1 in cord1...
  9. ncbi Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer
    Jeannette Bennicelli
    Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6069, USA
    Mol Ther 16:458-65. 2008
    ..The data demonstrate that AAV2.RPE65 delivers the RPE65 transgene efficiently and quickly to the appropriate target cells in vivo in animal models. This vector holds great promise for treatment of LCA due to RPE65 mutations...

Research Grants3

  1. Achromatopsia - Disease Mechanisms and Cone-Directed Gene Therapy
    Andras Komaromy; Fiscal Year: 2010
    ..This research proposal focuses on the development of a new gene therapy to recover diseased cones and their function and to restore day-vision ..
  2. Achromatopsia - Disease Mechanisms and Cone-Directed Gene Therapy
    Andras Komaromy; Fiscal Year: 2010
    ..This research proposal focuses on the development of a new gene therapy to recover diseased cones and their function and to restore day-vision ..