Research Topics
| Rachel A KohmanSummaryAffiliation: University of Illinois Country: USA Publications
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Detail Information
Publications
Wheel running attenuates microglia proliferation and increases expression of a proneurogenic phenotype in the hippocampus of aged miceRachel A Kohman
Department of Psychology, University of Illinois, Beckman Institute, Urbana, IL 61801 3873, USA
Brain Behav Immun 26:803-10. 2012..Additionally, running enhanced survival of new neurons in both age groups. Findings suggest that wheel running may attenuate microglia division and promote a proneurogenic phenotype in aged mice...
Aging microglia: relevance to cognition and neural plasticityRachel A Kohman
Department of Psychology, University of Illinois at Urbana Champaign, Beckman Institute, Urbana, IL, USA
Methods Mol Biol 934:193-218. 2012..Discovering factors that induce neuroinflammation and investigating potential preventative therapies is expected to uncover the ways of maintaining normal microglia activity in the aged brain...
Voluntary wheel running enhances contextual but not trace fear conditioningRachel A Kohman
Department of Psychology, University of Illinois, Beckman Institute, Urbana, IL 61801 3873, USA
Behav Brain Res 226:1-7. 2012....
Voluntary wheel running reverses age-induced changes in hippocampal gene expressionRachel A Kohman
Department of Psychology, Beckman Institute, University of Illinois, Urbana, Illinois, United States of America
PLoS ONE 6:e22654. 2011..Collectively, findings show that even late-onset exercise may attenuate age-related changes in gene expression and identifies possible pathways through which exercise may exert its beneficial effects...
Differential sensitivity to endotoxin exposure in young and middle-age miceRachel A Kohman
Department of Psychology, University of Illinois, Urbana, IL 61801, USA
Brain Behav Immun 24:486-92. 2010..Collectively, the data suggest that middle-age subjects are more sensitive to an immune insult...
New neurons generated from running are broadly recruited into neuronal activation associated with three different hippocampus-involved tasksPeter J Clark
Department of Psychology, The Beckman Institute, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
Hippocampus 22:1860-7. 2012....
Adult hippocampal neurogenesis and c-Fos induction during escalation of voluntary wheel running in C57BL/6J micePeter J Clark
Department of Psychology, The Beckman Institute, University of Illinois at Urbana Champaign, 405 N Mathews Ave, Urbana, IL 61801, USA
Behav Brain Res 213:246-52. 2010..We conclude that sustained running maintains a stable rate of neurogenesis above sedentary via activity-dependent increases in differentiation and survival, not proliferation, of progenitor cells in the C57BL/6J model...
The effects of age on lipopolysaccharide-induced cognitive deficits and interleukin-1β expressionAndrew J Tarr
Department of Psychology, Texas Christian University, Fort Worth, TX 76129, USA
Behav Brain Res 217:481-5. 2011..The findings suggest that age and immune activation combine to impair learning and memory consolidation processes, and that increased central IL-1β production may play a role...
Influence of prenatal stress on behavioral, endocrine, and cytokine responses to adulthood bacterial endotoxin exposureRachel A Kohman
Department of Psychology, Texas Christian University, Fort Worth, TX 76129, USA
Behav Brain Res 193:257-68. 2008....
Systemic lipopolysaccharide plus MPTP as a model of dopamine loss and gait instability in C57Bl/6J miceStefanie L Byler
Texas Christian University, Department of Psychology, Fort Worth, TX, USA
Behav Brain Res 198:434-9. 2009..These data are consistent with the view that nigrostriatal dopamine neurons might succumb after time to multiple toxic agents that independently may have only a transient, adverse effect...
Effects of minocycline on spatial learning, hippocampal neurogenesis and microglia in aged and adult miceRachel A Kohman
University of North Carolina Wilmington, Department of Psychology, Wilmington, NC 28403 5612, USA
Behav Brain Res 242:17-24. 2013..Collectively, the data indicate that treatment with minocycline may recover some aspects of cognitive decline associated with aging, but the effect appears to be unrelated to adult hippocampal neurogenesis...
Neurogenesis, inflammation and behaviorRachel A Kohman
Department of Psychology, Beckman Institute, 405 N Mathews Ave, Urbana, IL 61801, United States
Brain Behav Immun 27:22-32. 2013....
Bacterial endotoxin-induced behavioral alterations in two variations of the Morris water mazeNathan L Sparkman
Department of Psychology, Texas Christian University, Fort Worth, 76129, USA
Physiol Behav 86:244-51. 2005....
Peripheral lipopolysaccharide administration impairs two-way active avoidance conditioning in C57BL/6J miceNathan L Sparkman
Department of Psychology, Texas Christian University, TCU Box 298920, Fort Worth, TX 76129, USA
Physiol Behav 85:278-88. 2005..These results support the theory that peripheral immune stimuli may induce deleterious effects on learning, and extend the work to a negatively reinforced operant procedure...
