S C Kogan
Affiliation: University of Central Florida
- The PEBP2betaMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasiaS C Kogan
G W Hooper Foundation, University of California, San Francisco, CA 94143 0552, USA
Proc Natl Acad Sci U S A 95:11863-8. 1998..These results show that PEBP2betaMYH11 can impair neutrophil development and provide evidence that alterations of Pebp2 can contribute to the genesis of myelodysplasia...
- BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemiaS C Kogan
Department of Laboratory Medicine, University of California at San Francisco, San Francisco, California 94143, USA
J Exp Med 193:531-43. 2001..Our results indicate that genetic changes that inhibit apoptosis can cooperate with PMLRARalpha to initiate APL...
- Acute promyelocytic leukemia: a view from a mouseS C Kogan
Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA 94143 0128, USA
Blood Cells Mol Dis 26:620-5. 2000..Molecularly targeted therapies that either restore maturation or abrogate growth autonomy represent a hope for improving survival of patients with other subtypes of AML...
- Mouse models of acute promyelocytic leukemiaS C Kogan
Department of Laboratory Medicine and Comprehensive Cancer Center, University of California, San Francisco, Room S 864, 513 Parnassus Avenue, San Francisco, CA 94143 0100, USA
Curr Top Microbiol Immunol 313:3-29. 2007..Furthermore, preclinical studies utilizing these mice have advanced therapy for myeloid leukemia...