Research Topics
| Vikram D KodibagkarSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
Physical principles of quantitative nuclear magnetic resonance oximetryVikram D Kodibagkar
Cancer Imaging Program, Department of Radiology, UT Southwestern, Dallas, TX 75390 9058, USA
Front Biosci 13:1371-84. 2008..Practical considerations for choice of reporter molecules for in vivo measurements, general methodology and new developments are also described...- 19F-NMR detection of lacZ gene expression via the enzymic hydrolysis of 2-fluoro-4-nitrophenyl beta-D-galactopyranoside in vivo in PC3 prostate tumor xenografts in the mouseLi Liu
Department of Radiology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, Texas 75390 9058, USA
FASEB J 21:2014-9. 2007..More importantly, we demonstrate for the first time the ability to differentiate wild-type and lacZ-expressing prostate tumor xenografts in mice using this approach... 
A 19F-NMR approach using reporter molecule pairs to assess beta-galactosidase in human xenograft tumors in vivoJian Xin Yu
Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9058, USA
NMR Biomed 21:704-12. 2008..Most significantly, hydrolytic activity observed by 19F NMR corresponded to differential activity in lacZ-expressing tumors...- S-Gal, a novel 1H MRI reporter for beta-galactosidaseWeina Cui
Department of Radiology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9058, USA
Magn Reson Med 64:65-71. 2010..3,4-Cyclohexenoesculetin beta-D-galactopyranoside activation in combination with ferric ions introduces a novel approach for assaying enzyme activity by MRI in vivo... - Imaging beta-galactosidase activity using 19F chemical shift imaging of LacZ gene-reporter molecule 2-fluoro-4-nitrophenol-beta-D-galactopyranosideVikram D Kodibagkar
Department of Radiology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9058, USA
Magn Reson Imaging 24:959-62. 2006..19F CSI studies of enzyme activity and lacZ gene expression in 9L-glioma and MCF7 breast cancer cells are presented, providing further evidence for the utility of OFPNPG as a gene-reporter molecule for future in vivo studies... - Novel 1H NMR approach to quantitative tissue oximetry using hexamethyldisiloxaneVikram D Kodibagkar
Cancer Imaging Program, Department of Radiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-9058, USA
Magn Reson Med 55:743-8. 2006..In tumors, altering the inspired gas also produced significant (albeit generally smaller) changes. This new pO2 reporter molecule offers a potentially valuable new tool for investigating pO2 in vivo... - Proton imaging of siloxanes to map tissue oxygenation levels (PISTOL): a tool for quantitative tissue oximetryVikram D Kodibagkar
Cancer Imaging Program, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA
NMR Biomed 21:899-907. 2008..This new method offers a potentially valuable new tool to image pO(2) in vivo for any healthy or diseased state by (1)H MRI... - Dual 19F/1H MR gene reporter molecules for in vivo detection of β-galactosidaseJian Xin Yu
Department of Radiology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA
Bioconjug Chem 23:596-603. 2012..In the presence of ferric ions, the liberated aglycone generates intense proton MRI T(2) contrast. The dual modality approach allows both the detection of substrate and the imaging of product enhancing the confidence in enzyme detection... - Compressive sensing could accelerate 1H MR metabolic imaging in the clinicSairam Geethanath
Joint Graduate Program in Biomedical Engineering, UT Arlington and UT Southwestern Medical Center, Dallas, Tex, USA
Radiology 262:985-94. 2012..To retrospectively evaluate the fidelity of magnetic resonance (MR) spectroscopic imaging data preservation at a range of accelerations by using compressed sensing... - Synthesis and evaluation of novel enhanced gene reporter molecules: detection of beta-galactosidase activity using 19F NMR of trifluoromethylated aryl beta-D-galactopyranosidesJianxin Yu
Department of Radiology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA
Bioorg Med Chem 14:326-33. 2006..14 ppm) in breast cancer cells transfected to stably express lacZ... - Synthesis and characterization of a hypoxia-sensitive MRI probeFederico A Rojas-Quijano
Advanced Imaging Research Center, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA
Chemistry 18:9669-76. 2012..These results suggest that the nitroimidazole derivative might serve as a molecular reporter for discriminating hypoxic versus normoxic tissues by MRI... - On the potential for molecular imaging with Cerenkov luminescenceMatthew A Lewis
Advanced Radiological Sciences, Department of Radiology, UT Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9058, USA
Opt Lett 35:3889-91. 2010.... - 19F: a versatile reporter for non-invasive physiology and pharmacology using magnetic resonanceJian-xin Yu
Department of Radiology, The University of Texas Southwestern Medical Center at Dallas, Texas 75390-9058, USA
Curr Med Chem 12:819-48. 2005..Indeed, the large chemical shift range (approximately 300 ppm) can allow multiple agents to be examined, simultaneously, using NMR spectroscopy or chemical shift selective imaging... - Albumin-binding PARACEST agentsM Meser Ali
Department of Chemistry, University of Texas at Dallas, P O Box 830688, Richardson, TX 75083 0688, USA
J Biol Inorg Chem 12:855-65. 2007..Water proton relaxation enhancements of 135 and 171% were observed upon binding of Gd2 and Gd3 to HSA, respectively, at 298 K and pH 7.4...