Vikram D Kodibagkar

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi request reprint Physical principles of quantitative nuclear magnetic resonance oximetry
    Vikram D Kodibagkar
    Cancer Imaging Program, Department of Radiology, UT Southwestern, Dallas, TX 75390 9058, USA
    Front Biosci 13:1371-84. 2008
  2. ncbi request reprint 19F-NMR detection of lacZ gene expression via the enzymic hydrolysis of 2-fluoro-4-nitrophenyl beta-D-galactopyranoside in vivo in PC3 prostate tumor xenografts in the mouse
    Li Liu
    Department of Radiology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, Texas 75390 9058, USA
    FASEB J 21:2014-9. 2007
  3. pmc A 19F-NMR approach using reporter molecule pairs to assess beta-galactosidase in human xenograft tumors in vivo
    Jian Xin Yu
    Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9058, USA
    NMR Biomed 21:704-12. 2008
  4. pmc S-Gal, a novel 1H MRI reporter for beta-galactosidase
    Weina Cui
    Department of Radiology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9058, USA
    Magn Reson Med 64:65-71. 2010
  5. pmc Proton imaging of siloxanes to map tissue oxygenation levels (PISTOL): a tool for quantitative tissue oximetry
    Vikram D Kodibagkar
    Cancer Imaging Program, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    NMR Biomed 21:899-907. 2008
  6. ncbi request reprint Novel 1H NMR approach to quantitative tissue oximetry using hexamethyldisiloxane
    Vikram D Kodibagkar
    Cancer Imaging Program, Department of Radiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9058, USA
    Magn Reson Med 55:743-8. 2006
  7. ncbi request reprint Imaging beta-galactosidase activity using 19F chemical shift imaging of LacZ gene-reporter molecule 2-fluoro-4-nitrophenol-beta-D-galactopyranoside
    Vikram D Kodibagkar
    Department of Radiology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9058, USA
    Magn Reson Imaging 24:959-62. 2006
  8. pmc Dual 19F/1H MR gene reporter molecules for in vivo detection of β-galactosidase
    Jian Xin Yu
    Department of Radiology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Bioconjug Chem 23:596-603. 2012
  9. pmc Novel S-Gal(®) analogs as (1)H MRI reporters for in vivo detection of β-galactosidase
    Praveen K Gulaka
    Joint Program in Biomedical Engineering, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA
    Magn Reson Imaging 31:1006-11. 2013
  10. pmc Compressive sensing could accelerate 1H MR metabolic imaging in the clinic
    Sairam Geethanath
    Joint Graduate Program in Biomedical Engineering, UT Arlington and UT Southwestern Medical Center, Dallas, Tex, USA
    Radiology 262:985-94. 2012

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Physical principles of quantitative nuclear magnetic resonance oximetry
    Vikram D Kodibagkar
    Cancer Imaging Program, Department of Radiology, UT Southwestern, Dallas, TX 75390 9058, USA
    Front Biosci 13:1371-84. 2008
    ..Practical considerations for choice of reporter molecules for in vivo measurements, general methodology and new developments are also described...
  2. ncbi request reprint 19F-NMR detection of lacZ gene expression via the enzymic hydrolysis of 2-fluoro-4-nitrophenyl beta-D-galactopyranoside in vivo in PC3 prostate tumor xenografts in the mouse
    Li Liu
    Department of Radiology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, Texas 75390 9058, USA
    FASEB J 21:2014-9. 2007
    ..More importantly, we demonstrate for the first time the ability to differentiate wild-type and lacZ-expressing prostate tumor xenografts in mice using this approach...
  3. pmc A 19F-NMR approach using reporter molecule pairs to assess beta-galactosidase in human xenograft tumors in vivo
    Jian Xin Yu
    Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9058, USA
    NMR Biomed 21:704-12. 2008
    ..Most significantly, hydrolytic activity observed by 19F NMR corresponded to differential activity in lacZ-expressing tumors...
  4. pmc S-Gal, a novel 1H MRI reporter for beta-galactosidase
    Weina Cui
    Department of Radiology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9058, USA
    Magn Reson Med 64:65-71. 2010
    ..3,4-Cyclohexenoesculetin beta-D-galactopyranoside activation in combination with ferric ions introduces a novel approach for assaying enzyme activity by MRI in vivo...
  5. pmc Proton imaging of siloxanes to map tissue oxygenation levels (PISTOL): a tool for quantitative tissue oximetry
    Vikram D Kodibagkar
    Cancer Imaging Program, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    NMR Biomed 21:899-907. 2008
    ..This new method offers a potentially valuable new tool to image pO(2) in vivo for any healthy or diseased state by (1)H MRI...
  6. ncbi request reprint Novel 1H NMR approach to quantitative tissue oximetry using hexamethyldisiloxane
    Vikram D Kodibagkar
    Cancer Imaging Program, Department of Radiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9058, USA
    Magn Reson Med 55:743-8. 2006
    ..In tumors, altering the inspired gas also produced significant (albeit generally smaller) changes. This new pO2 reporter molecule offers a potentially valuable new tool for investigating pO2 in vivo...
  7. ncbi request reprint Imaging beta-galactosidase activity using 19F chemical shift imaging of LacZ gene-reporter molecule 2-fluoro-4-nitrophenol-beta-D-galactopyranoside
    Vikram D Kodibagkar
    Department of Radiology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9058, USA
    Magn Reson Imaging 24:959-62. 2006
    ..19F CSI studies of enzyme activity and lacZ gene expression in 9L-glioma and MCF7 breast cancer cells are presented, providing further evidence for the utility of OFPNPG as a gene-reporter molecule for future in vivo studies...
  8. pmc Dual 19F/1H MR gene reporter molecules for in vivo detection of β-galactosidase
    Jian Xin Yu
    Department of Radiology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Bioconjug Chem 23:596-603. 2012
    ..In the presence of ferric ions, the liberated aglycone generates intense proton MRI T(2) contrast. The dual modality approach allows both the detection of substrate and the imaging of product enhancing the confidence in enzyme detection...
  9. pmc Novel S-Gal(®) analogs as (1)H MRI reporters for in vivo detection of β-galactosidase
    Praveen K Gulaka
    Joint Program in Biomedical Engineering, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA
    Magn Reson Imaging 31:1006-11. 2013
    ..Thus, C3-GD successfully detects β-galactosidase activity in vivo and shows promise as a lacZ gene (1)H MR reporter molecule...
  10. pmc Compressive sensing could accelerate 1H MR metabolic imaging in the clinic
    Sairam Geethanath
    Joint Graduate Program in Biomedical Engineering, UT Arlington and UT Southwestern Medical Center, Dallas, Tex, USA
    Radiology 262:985-94. 2012
    ..To retrospectively evaluate the fidelity of magnetic resonance (MR) spectroscopic imaging data preservation at a range of accelerations by using compressed sensing...
  11. ncbi request reprint Synthesis and evaluation of novel enhanced gene reporter molecules: detection of beta-galactosidase activity using 19F NMR of trifluoromethylated aryl beta-D-galactopyranosides
    Jianxin Yu
    Department of Radiology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA
    Bioorg Med Chem 14:326-33. 2006
    ..14 ppm) in breast cancer cells transfected to stably express lacZ...
  12. pmc Dual-modality, dual-functional nanoprobes for cellular and molecular imaging
    Jyothi U Menon
    Department of Radiology, UT Southwestern Medical Center at Dallas, Dallas, TX, USA
    Theranostics 2:1199-207. 2012
    ..As proof of principle, these nanoprobes were successfully used for fluorescence imaging and for measuring pO(2) changes in cells by magnetic resonance imaging, in vitro, thus showing potential for in vivo applications...
  13. pmc Synthesis and characterization of a hypoxia-sensitive MRI probe
    Federico A Rojas-Quijano
    Advanced Imaging Research Center, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA
    Chemistry 18:9669-76. 2012
    ..These results suggest that the nitroimidazole derivative might serve as a molecular reporter for discriminating hypoxic versus normoxic tissues by MRI...
  14. pmc On the potential for molecular imaging with Cerenkov luminescence
    Matthew A Lewis
    Advanced Radiological Sciences, Department of Radiology, UT Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9058, USA
    Opt Lett 35:3889-91. 2010
    ....
  15. ncbi request reprint 19F: a versatile reporter for non-invasive physiology and pharmacology using magnetic resonance
    Jian Xin Yu
    Department of Radiology, The University of Texas Southwestern Medical Center at Dallas, Texas 75390 9058, USA
    Curr Med Chem 12:819-48. 2005
    ..Indeed, the large chemical shift range (approximately 300 ppm) can allow multiple agents to be examined, simultaneously, using NMR spectroscopy or chemical shift selective imaging...
  16. pmc Albumin-binding PARACEST agents
    M Meser Ali
    Department of Chemistry, University of Texas at Dallas, P O Box 830688, Richardson, TX 75083 0688, USA
    J Biol Inorg Chem 12:855-65. 2007
    ..Water proton relaxation enhancements of 135 and 171% were observed upon binding of Gd2 and Gd3 to HSA, respectively, at 298 K and pH 7.4...