James J Kobie

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc 9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity
    James J Kobie
    Division of Allergy, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 7:e35356. 2012
  2. doi request reprint T helper cytokine patterns: defined subsets, random expression, and external modulation
    Tim R Mosmann
    David H Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, NY 14642, USA
    Immunol Res 45:173-84. 2009
  3. pmc Anti-idiotypic monobodies for immune response profiling
    Mark A Sullivan
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Methods 58:62-8. 2012
  4. pmc 9G4+ antibodies isolated from HIV-infected patients neutralize HIV-1 and have distinct autoreactivity profiles
    Danielle C Alcena
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 8:e85098. 2013
  5. pmc Decreased influenza-specific B cell responses in rheumatoid arthritis patients treated with anti-tumor necrosis factor
    James J Kobie
    Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 695, Rochester, NY 14642, USA
    Arthritis Res Ther 13:R209. 2011
  6. pmc Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine-mediated T cell hyporesponsiveness
    Shannon P Hilchey
    James P Wilmot Cancer Center, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Immunol 183:6157-66. 2009
  7. pmc Peak frequencies of circulating human influenza-specific antibody secreting cells correlate with serum antibody response after immunization
    Jessica L Halliley
    Division of Pulmonary and Critical Care Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Vaccine 28:3582-7. 2010
  8. pmc Human basophils express amphiregulin in response to T cell-derived IL-3
    Yilin Qi
    David H Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Allergy Clin Immunol 126:1260-6.e4. 2010
  9. doi request reprint Characterization of cell seeding and specific capture of B cells in microbubble well arrays
    Meghan C Jones
    Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA
    Biomed Microdevices 15:453-63. 2013

Collaborators

Detail Information

Publications9

  1. pmc 9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity
    James J Kobie
    Division of Allergy, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 7:e35356. 2012
    ..Our results suggest that the development of HIV BNAbs is not merely a consequence of a general breakdown in tolerance, but rather a more intricate expansion of selective autoreactive B cells and antibodies...
  2. doi request reprint T helper cytokine patterns: defined subsets, random expression, and external modulation
    Tim R Mosmann
    David H Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, NY 14642, USA
    Immunol Res 45:173-84. 2009
    ..Additional contributions to diversity may include new committed subsets, random expression of only part of the committed pattern, and modification of the expression patterns by cytokines and other mediators...
  3. pmc Anti-idiotypic monobodies for immune response profiling
    Mark A Sullivan
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Methods 58:62-8. 2012
    ....
  4. pmc 9G4+ antibodies isolated from HIV-infected patients neutralize HIV-1 and have distinct autoreactivity profiles
    Danielle C Alcena
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 8:e85098. 2013
    ..Further studies of 9G4+ B cells may shed light on the regulation of B cell tolerance and interface between the generation of specific autoreactivities and the induction of antiviral immunity in persons living with HIV. ..
  5. pmc Decreased influenza-specific B cell responses in rheumatoid arthritis patients treated with anti-tumor necrosis factor
    James J Kobie
    Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 695, Rochester, NY 14642, USA
    Arthritis Res Ther 13:R209. 2011
    ..Therefore, we asked if short-term effector (d5-d10) and memory (1 month or later) B cell responses to antigen were compromised in RA patients treated with anti-TNF therapy...
  6. pmc Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine-mediated T cell hyporesponsiveness
    Shannon P Hilchey
    James P Wilmot Cancer Center, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Immunol 183:6157-66. 2009
    ..In addition, these studies suggest that the A(2A/B) AR as well as CD39 are novel pharmacological targets for augmenting cancer immunotherapy...
  7. pmc Peak frequencies of circulating human influenza-specific antibody secreting cells correlate with serum antibody response after immunization
    Jessica L Halliley
    Division of Pulmonary and Critical Care Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Vaccine 28:3582-7. 2010
    ..The kinetics of this response and the relationship of circulating ASCs to protective antibody titers have not been completely explored...
  8. pmc Human basophils express amphiregulin in response to T cell-derived IL-3
    Yilin Qi
    David H Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Allergy Clin Immunol 126:1260-6.e4. 2010
    ..Amphiregulin produced by mouse hematopoietic cells contributes to the elimination of a nematode infection by a type 2 effector response...
  9. doi request reprint Characterization of cell seeding and specific capture of B cells in microbubble well arrays
    Meghan C Jones
    Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA
    Biomed Microdevices 15:453-63. 2013
    ..These results emphasize the importance of using primary cells in technology development and suggest the need to utilize B cell capture agents that are insensitive to cell activation...