Research Topics
Species | Nerissa U KoSummaryAffiliation: University of California Country: USA Publications
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Publications
Endothelial nitric oxide synthase polymorphism (-786T->C) and increased risk of angiographic vasospasm after aneurysmal subarachnoid hemorrhageNerissa U Ko
Department of Neurology, University of California, San Francisco, USA
Stroke 39:1103-8. 2008..Decreased availability of nitric oxide (NO) may be crucial in its pathogenesis. We hypothesized that endothelial NO synthase (eNOS) polymorphisms may determine susceptibility to vasospasm in SAH patients...
Common variants in interleukin-1-Beta gene are associated with intracranial hemorrhage and susceptibility to brain arteriovenous malformationHelen Kim
Center for Cerebrovascular Research, Department of Anesthesia and Perioperative Care, University of California San Francisco, 1001 Potrero Avenue, San Francisco, CA 94110, USA
Cerebrovasc Dis 27:176-82. 2009..The aim of this study was to investigate associations between single nucleotide polymorphisms (SNPs) in IL-1beta and intracranial hemorrhage (ICH) in the natural course of brain arteriovenous malformation (BAVM) patients...
Association of tumor necrosis factor-alpha-238G>A and apolipoprotein E2 polymorphisms with intracranial hemorrhage after brain arteriovenous malformation treatmentAchal S Achrol
Center for Cerebrovascular Research and Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94110, USA
Neurosurgery 61:731-9; discussion 740. 2007..We hypothesized that the risk of posttreatment ICH would also be greater in patients with brain arteriovenous malformations with these genotypes...
Visual grading system for vasospasm based on perfusion CT imaging: comparisons with conventional angiography and quantitative perfusion CTMax Wintermark
Department of Radiology, University of California, San Francisco, CA 94143, USA
Cerebrovasc Dis 26:163-70. 2008..The purpose of this study was to compare simple visual grading of perfusion CT (PCT) maps to a more quantitative, threshold-based interpretation of PCT parameters in the characterization of presence and severity of vasospasm...
Ten-year detection rate of brain arteriovenous malformations in a large, multiethnic, defined populationRodney A Gabriel
UCSF Department of Anesthesia and Perioperative Care, 1001 Potrero Ave, Room 3C 38, San Francisco, CA 94110, USA
Stroke 41:21-6. 2010....
Racial/Ethnic differences in longitudinal risk of intracranial hemorrhage in brain arteriovenous malformation patientsHelen Kim
Center for Cerebrovascular Research, Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94115, USA
Stroke 38:2430-7. 2007..We evaluated whether race/ethnicity was a risk factor for ICH in the natural course in a large, multiethnic cohort of patients with brain arteriovenous malformation followed longitudinally...
Cerebral blood flow changes after endovascular treatment of cerebrovascular stenosesNerissa U Ko
Department of Neurology, University of California, San Francisco 94110, USA
AJNR Am J Neuroradiol 26:538-42. 2005..However, the increased CBF appeared to be unrelated to the degree of vascular stenosis, suggesting a relationship to availability of collateral flow pathways or a neurogenic influence...
Estimation of fusiform intracranial aneurysm growth by serial magnetic resonance imagingBradley P Dispensa
Department of Anesthesia and Perioperative Care and Center for Cerebrovascular Research, University of California San Francisco, San Francisco, California 94110, USA
J Magn Reson Imaging 26:177-83. 2007..Intracranial aneurysm (IA) growth is associated with increased morbidity. We sought to establish a quantitative computational method based on contrast-enhanced MR angiography (CE-MRA) for estimating aneurysmal volume changes over time...
Elevated BNP is associated with vasospasm-independent cerebral infarction following aneurysmal subarachnoid hemorrhagePam R Taub
Department of Medicine, Cardiology Division, University of California, San Diego, CA 94114, USA
Neurocrit Care 15:13-8. 2011..We sought to determine whether elevated levels of BNP are independently associated with radiographic cerebral infarction after SAH...
Apolipoprotein E epsilon 2 is associated with new hemorrhage risk in brain arteriovenous malformationsLudmila Pawlikowska
The Cardiovascular Research Institute, University of California, San Francisco 94110, USA
Neurosurgery 58:838-43; discussion 838-43. 2006..Identification of genetic variants associated with increased new ICH risk would facilitate risk stratification and guide therapeutic intervention...
Magnetic resonance perfusion tracks 133Xe cerebral blood flow changes after carotid stentingNerissa U Ko
Department of Neurology, University of California, San Francisco, USA
Stroke 36:676-8. 2005..CONCLUSIONS: Bolus-tracking MR perfusion correlates with 133Xe-CBF in estimating postprocedural increases in blood flow but may underestimate the magnitude of the change with higher relative changes...
Improvement in intensive care unit outcomes in patients with subarachnoid hemorrhage after initiation of neurointensivist co-managementS Andrew Josephson
Department of Neurology, University of California, San Francisco, California 94143, USA
J Neurosurg 112:626-30. 2010..No study to date has examined the role of neurointensivists specifically in subarachnoid hemorrhage (SAH) management. This study examined the use of a team-based neurointensivist co-management approach...
Neurotoxicity of intra-arterial papaverine preserved with chlorobutanol used for the treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhageWade S Smith
Department of Neurology, University of California, San Francisco, Calif 94134 0114, USA
Stroke 35:2518-22. 2004..Papaverine is used to vasodilate cerebral arteries undergoing vasospasm from subarachnoid hemorrhage. However, papaverine inhibits cellular respiration in vitro and could cause neurotoxicity in humans...
Accuracy of dynamic perfusion CT with deconvolution in detecting acute hemispheric strokeMax Wintermark
Department of Radiology, Neuroradiology Section, University of California, San Francisco, USA
AJNR Am J Neuroradiol 26:104-12. 2005..2%, 91.8%, and 87.9% in showing the extent. CONCLUSION: Dynamic PCT maps are more accurate than nonenhanced CT in detecting hemispheric strokes. Despite limited spatial coverage, PCT is highly reliable to assess the stroke extent...
Research Grants
- Apolipoprotein E and Outcomes in Subarachnoid HemorrhageNerissa Ko; Fiscal Year: 2007..A program of didactic courses and mentoring in this project will build upon the candidate's clinical training, and allow her to develop into an independent clinical investigator in neurovascular neurology. ..
