Research Topics
| A H KoSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
A phase I trial of nab-paclitaxel, gemcitabine, and capecitabine for metastatic pancreatic cancerAndrew H Ko
Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, 94115, USA
Cancer Chemother Pharmacol 70:875-81. 2012....
Optimizing the administration of fixed-dose rate gemcitabine plus capecitabine using an alternating-week schedule: a dose finding and early efficacy study in advanced pancreatic and biliary carcinomasAndrew H Ko
Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA
Am J Clin Oncol 35:411-7. 2012....
A phase II randomized study of cetuximab and bevacizumab alone or in combination with gemcitabine as first-line therapy for metastatic pancreatic adenocarcinomaAndrew H Ko
Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, 1600 Divisadero Street, 4th Floor, Box 1705, San Francisco, CA 94115, USA
Invest New Drugs 30:1597-606. 2012..To our knowledge, this is one of the first trials to evaluate a completely noncytotoxic regimen in the first-line treatment of advanced pancreatic cancer. (ClinicalTrials.gov number, NCT00326911)...
A phase II study of bevacizumab plus erlotinib for gemcitabine-refractory metastatic pancreatic cancerAndrew H Ko
University of California at San Francisco Helen Diller Family Comprehensive Cancer Center, 1600 Divisadero Street, 4th Floor, Box 1705, San Francisco, CA 94115, USA
Cancer Chemother Pharmacol 66:1051-7. 2010..Based on potential for additive or synergistic activity by concurrent inhibition of VEGF and EGFR, we conducted a phase II study evaluating the combination of bevacizumab plus erlotinib in this patient population...
A phase II study evaluating bevacizumab in combination with fixed-dose rate gemcitabine and low-dose cisplatin for metastatic pancreatic cancer: is an anti-VEGF strategy still applicable?Andrew H Ko
University of California at San Francisco Comprehensive Cancer Center, 1600 Divisadero Street, 4th Floor, Box 1705, San Francisco, CA, 94115, USA
Invest New Drugs 26:463-71. 2008..The objectives of this study were to determine safety and efficacy in chemotherapy-naive patients with metastatic pancreatic cancer receiving bevacizumab in combination with fixed-dose rate (FDR) gemcitabine and low-dose cisplatin...
Excess toxicity associated with docetaxel and irinotecan in patients with metastatic, gemcitabine-refractory pancreatic cancer: results of a phase II studyAndrew H Ko
University of California at San Francisco Comprehensive Cancer Center, San Francisco, California 94115, USA
Cancer Invest 26:47-52. 2008..We, therefore, evaluated this regimen in patients with gemcitabine-refractory disease...
Future strategies for targeted therapies and tailored patient management in pancreatic cancerAndrew H Ko
Department of Medicine, University of California, San Francisco Comprehensive Cancer Center, San Francisco, CA, USA
Semin Oncol 34:354-64. 2007..A newer strategy worth pursuing involves tailoring an individual patient's therapy according to the molecular characteristics of both host and tumor, as has shown promise in other solid tumor types...
A phase II study of fixed-dose rate gemcitabine plus low-dose cisplatin followed by consolidative chemoradiation for locally advanced pancreatic cancerAndrew H Ko
Division of Hematology Oncology, University of California at San Francisco, San Francisco, CA 94115, USA
Int J Radiat Oncol Biol Phys 68:809-16. 2007..We conducted a Phase II nonrandomized trial to evaluate sequential chemotherapy followed by chemoradiation in this patient population...
Current and future strategies for combined-modality therapy in pancreatic cancerAndrew H Ko
Comprehensive Cancer Center, University of California at San Francisco, 1600 Divisadero Street, 4th Floor, San Francisco, CA 94115, USA
Curr Oncol Rep 4:202-12. 2002....
Phase II study of fixed dose rate gemcitabine with cisplatin for metastatic adenocarcinoma of the pancreasAndrew H Ko
University of California at San Francisco Comprehensive Cancer Center, San Francisco, CA 94115, USA
J Clin Oncol 24:379-85. 2006..The objectives of this study were to determine safety and efficacy in patients with metastatic pancreatic cancer treated with FDR gemcitabine in combination with low-dose cisplatin...
Treatment of metastatic pancreatic cancerAndrew H Ko
Division of Medical Oncology, University of California at San Francisco Comprehensive Cancer Center, San Francisco, California 94115, USA
J Natl Compr Canc Netw 3:627-36. 2005..This article provides the evidence to support each of these approaches and highlights future directions in the management of metastatic pancreatic cancer...
Systemic therapy for pancreatic cancerAndrew H Ko
San Francisco Comprehensive Cancer Center, University of California, San Francisco, CA, USA
Semin Radiat Oncol 15:245-53. 2005..The combination of standard cytotoxic agents and these newer targeted compounds offers promise that we will be able to make significant inroads in improving clinical outcomes for patients with advanced pancreatic cancer...
Clinical outcomes associated with very late relapses in diffuse large cell lymphomaAndrew H Ko
Division of Hematology Oncology, University of California, San Francisco Medical Center, San Francisco, CA 94115, USA
Leuk Lymphoma 43:1789-93. 2002..The overall poor prognosis in this group of patients justifies the use of more aggressive treatment approaches in the future, such as high dose therapy with stem cell support, rather than conventional salvage chemotherapy regimens...
Serum CA19-9 response as a surrogate for clinical outcome in patients receiving fixed-dose rate gemcitabine for advanced pancreatic cancerA H Ko
University of California at San Francisco Comprehensive Cancer Center, 1600 Divisadero Street, 4th Floor, Box 1705, San Francisco, CA 94115, USA
Br J Cancer 93:195-9. 2005....
Serum CA19-9 decline compared to radiographic response as a surrogate for clinical outcomes in patients with metastatic pancreatic cancer receiving chemotherapyDerrick Wong
University of California at San Francisco Comprehensive Cancer Center, San Francisco, CA, USA
Pancreas 37:269-74. 2008..Serum carbohydrate antigen 19-9 (CA19-9) has never been compared to radiographic objective response as a surrogate for clinical outcomes in patients receiving chemotherapy for metastatic pancreatic cancer...
A phase I study of a 2-day lapatinib chemosensitization pulse preceding nanoparticle albumin-bound Paclitaxel for advanced solid malignanciesAmy J Chien
Department of Medicine, University of California San Francisco, San Francisco, California 94143 0875, USA
Clin Cancer Res 15:5569-75. 2009..This study investigates the clinical relevance of this approach...
Radiation therapy in operable and locally advanced pancreatic cancerAndrew H Ko
Division of Hematology Oncology, University of California San Francisco Comprehensive Cancer Center, San Francisco, California, USA
J Natl Compr Canc Netw 8:1022-31. 2010....
Pancreatic cancer and medical history in a population-based case-control study in the San Francisco Bay Area, CaliforniaAndrew H Ko
Division of Hematology Oncology, University of California San Francisco, San Francisco, CA, USA
Cancer Causes Control 18:809-19. 2007..To determine the association between pancreatic cancer and medical conditions...
Tumor-associated hypoglycemia from metastatic colorectal adenocarcinoma: case report and review of the literatureAndrew H Ko
Division of Hematology and Oncology, University of California, San Francisco, California 94115, USA
Dig Dis Sci 48:192-6. 2003
