M M Knudson

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Nonoperative management of solid organ injuries. Past, present, and future
    M M Knudson
    Department of Surgery, University of California, San Francisco, USA
    Surg Clin North Am 79:1357-71. 1999
  2. pmc Acquired A amyloidosis from injection drug use presenting with atraumatic splenic rupture in a hospitalized patient: a case report
    Garrett R Roll
    Department of Surgery, University of California San Francisco, San Francisco, USA
    J Med Case Reports 5:29. 2011
  3. pmc Identification of complex metabolic states in critically injured patients using bioinformatic cluster analysis
    Mitchell J Cohen
    Department of Surgery, University of California, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    Crit Care 14:R10. 2010
  4. ncbi request reprint Venous thromboembolism after trauma
    M Margaret Knudson
    Department of Surgery, University of California, San Francisco, California 94110, USA
    Curr Opin Crit Care 10:539-48. 2004
  5. pmc Thromboembolism after trauma: an analysis of 1602 episodes from the American College of Surgeons National Trauma Data Bank
    M Margaret Knudson
    Department of Surgery, San Francisco General Hospital, CA 94110, USA
    Ann Surg 240:490-6; discussion 496-8. 2004
  6. ncbi request reprint Improving outcomes in pediatric trauma care: essential characteristics of the trauma center
    M Margaret Knudson
    Department of Surgery, University of California San Francisco, USA
    J Trauma 63:S140-2. 2007
  7. doi request reprint Trauma training in simulation: translating skills from SIM time to real time
    M Margaret Knudson
    Department of Surgery, University of California, San Francisco, California, USA
    J Trauma 64:255-63; discussion 263-4. 2008
  8. ncbi request reprint Tissue oxygen monitoring during hemorrhagic shock and resuscitation: a comparison of lactated Ringer's solution, hypertonic saline dextran, and HBOC-201
    M Margaret Knudson
    San Francisco Injury Center, University of California, USA
    J Trauma 54:242-52. 2003
  9. doi request reprint Three thousand seven hundred thirty-eight posttraumatic pulmonary emboli: a new look at an old disease
    M Margaret Knudson
    Department of Surgery, University of California, San Francisco, CA 94110, USA
    Ann Surg 254:625-32. 2011
  10. doi request reprint Trauma/critical care surgery
    M Margaret Knudson
    University of California, San Francisco, Campus Box 0807, San Francisco, CA 94143 0807, USA
    Am J Surg 199:266-8. 2010

Research Grants

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Nonoperative management of solid organ injuries. Past, present, and future
    M M Knudson
    Department of Surgery, University of California, San Francisco, USA
    Surg Clin North Am 79:1357-71. 1999
    ..Currently, the morbidity and mortality rates of nonoperative management are acceptably low, but surgeons still must monitor their results carefully as they apply these methods more liberally among injured patients...
  2. pmc Acquired A amyloidosis from injection drug use presenting with atraumatic splenic rupture in a hospitalized patient: a case report
    Garrett R Roll
    Department of Surgery, University of California San Francisco, San Francisco, USA
    J Med Case Reports 5:29. 2011
    ..abstract:..
  3. pmc Identification of complex metabolic states in critically injured patients using bioinformatic cluster analysis
    Mitchell J Cohen
    Department of Surgery, University of California, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    Crit Care 14:R10. 2010
    ..We hypothesized that processing of multivariate data using hierarchical clustering techniques would allow identification of otherwise hidden patient physiologic patterns that would be predictive of outcome...
  4. ncbi request reprint Venous thromboembolism after trauma
    M Margaret Knudson
    Department of Surgery, University of California, San Francisco, California 94110, USA
    Curr Opin Crit Care 10:539-48. 2004
    ..Special attention is paid to patients with spinal cord injury, patients with head injury, and pediatric trauma patients...
  5. pmc Thromboembolism after trauma: an analysis of 1602 episodes from the American College of Surgeons National Trauma Data Bank
    M Margaret Knudson
    Department of Surgery, San Francisco General Hospital, CA 94110, USA
    Ann Surg 240:490-6; discussion 496-8. 2004
    ..Venous thromboembolic events (VTE) are potentially preventable causes of morbidity and mortality after injury. We hypothesized that the current clinical incidence of VTE is relatively low and that VTE risk factors could be identified...
  6. ncbi request reprint Improving outcomes in pediatric trauma care: essential characteristics of the trauma center
    M Margaret Knudson
    Department of Surgery, University of California San Francisco, USA
    J Trauma 63:S140-2. 2007
    ..Each of these areas encompasses important unanswered questions...
  7. doi request reprint Trauma training in simulation: translating skills from SIM time to real time
    M Margaret Knudson
    Department of Surgery, University of California, San Francisco, California, USA
    J Trauma 64:255-63; discussion 263-4. 2008
    ..Simulation may have a role in this educational process, but only if it can be demonstrated that skills learned in a simulated environment translate into enhanced performance in real-life trauma situations...
  8. ncbi request reprint Tissue oxygen monitoring during hemorrhagic shock and resuscitation: a comparison of lactated Ringer's solution, hypertonic saline dextran, and HBOC-201
    M Margaret Knudson
    San Francisco Injury Center, University of California, USA
    J Trauma 54:242-52. 2003
    ..We further hypothesized that changes in tissue oxygen tension measurements in the deltoid muscle would reflect the changes seen in the liver and could thus be used as a monitor of splanchnic resuscitation...
  9. doi request reprint Three thousand seven hundred thirty-eight posttraumatic pulmonary emboli: a new look at an old disease
    M Margaret Knudson
    Department of Surgery, University of California, San Francisco, CA 94110, USA
    Ann Surg 254:625-32. 2011
    ..This study was undertaken to determine the current incidence of pulmonary embolism (PE) and its attributable mortality after injury...
  10. doi request reprint Trauma/critical care surgery
    M Margaret Knudson
    University of California, San Francisco, Campus Box 0807, San Francisco, CA 94143 0807, USA
    Am J Surg 199:266-8. 2010
    ..However, careers in trauma/critical care and emergency surgery can offer a controlled lifestyle, challenging cases that cross over many disciplines, and a rich field for scientific investigation...
  11. ncbi request reprint Timing of urgent thoracotomy for hemorrhage after trauma: a multicenter study
    R Karmy-Jones
    Department of Surgery, Campus Box 359796, 325 Ninth Ave, Harborview Medical Center, Seattle, WA 98104, USA
    Arch Surg 136:513-8. 2001
    ..It is possible to quantify an amount of thoracic hemorrhage, after blunt and penetrating injury, at which delay of thoracotomy is associated with increased mortality...
  12. doi request reprint Use of hemoglobin-based oxygen-carrying solution-201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage: laboratory investigation
    Guy Rosenthal
    Department of Neurosurgery, University of California, San Francisco, CA 94117, USA
    J Neurosurg 108:575-87. 2008
    ..We studied the effects of hemoglobin-based oxygen-carrying (HBOC)-201 solution compared with lactated Ringer (LR) solution in a large animal model of brain injury and hemorrhage, in a blinded prospective randomized study...
  13. ncbi request reprint Trauma assessment training with a patient simulator: a prospective, randomized study
    Seong K Lee
    Department of Surgery, University of California, San Francisco, California 94110, USA
    J Trauma 55:651-7. 2003
    ..We hypothesized that trauma assessment training on a patient simulator would be as effective as training with a more traditional moulage patient/actor...
  14. ncbi request reprint Carbon dioxide reactivity and pressure autoregulation of brain tissue oxygen
    J C Hemphill
    Department of Neurology, University of California San Francisco, 94143-0112, USA
    Neurosurgery 48:377-83; discussion 383-4. 2001
    ..The relationship of PbrO2 with ET-CO2 and MAP appears to be similar to those historically established for CBF with ET-CO2 and MAP. This suggests that, under normal conditions, PbrO2 is strongly influenced by factors that regulate CBF...
  15. pmc Delayed internal fixation of femoral shaft fracture reduces mortality among patients with multisystem trauma
    Saam Morshed
    University of California at San Francisco, San Francisco General Hospital, 1001 Potrero Avenue, Room 3A 36, San Francisco, CA 94110, USA
    J Bone Joint Surg Am 91:3-13. 2009
    ..The appropriate timing of fracture repair is controversial. The purpose of the present study was to assess the effect of timing of internal fixation on mortality in patients with multisystem trauma...
  16. ncbi request reprint Continuous muscle tissue oxygenation in critically injured patients: a prospective observational study
    Danagra G Ikossi
    Department of Surgery, University of California, San Francisco and the San Francisco Injury Center for Research and Prevention, San Francisco, California, USA
    J Trauma 61:780-8; discussion 788-90. 2006
    ..A continuous, sensitive, and accurate measure of resuscitation after injury remains elusive...
  17. ncbi request reprint Prehospital hypoxia affects outcome in patients with traumatic brain injury: a prospective multicenter study
    John H Chi
    Department of Surgery, The University of California, San Francisco and the San Francisco Injury Center for Research and Prevention, San Francisco, California 94143, USA
    J Trauma 61:1134-41. 2006
    ....
  18. doi request reprint Refining resuscitation strategies using tissue oxygen and perfusion monitoring in critical organ beds
    Jennifer J Wan
    Department of Surgery, University of California, San Francisco and the San Francisco Injury Center for Research and Prevention, San Francisco, California, USA
    J Trauma 66:353-7. 2009
    ..We further hypothesized that PmO2 would decrease even as PbrO2 increased when vasopressor therapy was used...
  19. ncbi request reprint Controlled cortical impact in swine: pathophysiology and biomechanics
    Geoffrey T Manley
    Department of Neurological Surgery, University of California, San Francisco, California 94110, USA
    J Neurotrauma 23:128-39. 2006
    ..Physiological parameters after injury are readily monitored in a setting mimicking conditions of an intensive care unit, establishing a more clinically relevant experimental model for future investigations...
  20. ncbi request reprint Small-volume resuscitation with HBOC-201: effects on cardiovascular parameters and brain tissue oxygen tension in an out-of-hospital model of hemorrhage in swine
    Seong K Lee
    San Francisco Injury Center, University of California, San Francisco, School of Medicine, San Francisco, CA, USA
    Acad Emerg Med 9:969-76. 2002
    ....
  21. doi request reprint Trauma, transfusions, and use of recombinant factor VIIa: A multicenter case registry report of 380 patients from the Western Trauma Association
    M Margaret Knudson
    Department of Surgery, University of California, San Francisco, USA
    J Am Coll Surg 212:87-95. 2011
    ..We hypothesized that we could describe the setting in which rFVIIa would be most successful in arresting hemorrhage after injury...
  22. ncbi request reprint Urgent and emergent thoracotomy for penetrating chest trauma
    Riyad Karmy-Jones
    Department of Surgery, Box 359796, 325 Ninth Avenue, Harborview Medical Center, Seattle, WA 98104, USA
    J Trauma 56:664-8; discussion 668-9. 2004
    ..Although the major factor in outcome is presenting physiology, the site of the TCY may influence survival, with the operating room offering a superior environment to the emergency room...
  23. ncbi request reprint Small-volume resuscitation with the hemoglobin substitute HBOC-201: effect on brain tissue oxygenation
    Geoffrey T Manley
    School of Medicine, University of California San Francisco, San Francisco Injury Center, Department of Neurological Surgery, USA
    Adv Exp Med Biol 530:311-7. 2003
    ..To investigate the effects of small-volume resuscitation with a hemoglobin based oxygen carrier on brain tissue oxygen tension (PbrO2) in hemorrhaged swine...
  24. ncbi request reprint Down's syndrome, precocious puberty, and transverse vaginal septum: an unusual cause of abdominal pain
    T Quinn
    Department of Surgery, University of California, San Francisco, CA 94110, USA
    J Pediatr Surg 36:641-3. 2001
    ..The diagnosis was facilitated using a combination of computed tomography and ultrasound scanning. J Pediatr Surg 36:641-643...
  25. ncbi request reprint Management of traumatic lung injury: a Western Trauma Association Multicenter review
    R Karmy-Jones
    Department of Surgery, Harborview Medical Center, Seattle, Washington 98104, USA
    J Trauma 51:1049-53. 2001
    ..Improved outcomes following lung injury have been reported using "lung sparing" techniques...
  26. ncbi request reprint Hypotension, hypoxia, and head injury: frequency, duration, and consequences
    G Manley
    Department of Surgery, San Francisco General Hospital, Ward 3A, 1001 Potrero Ave, San Francisco, CA 94110, USA
    Arch Surg 136:1118-23. 2001
    ..These prospective data reinforce the need for early continuous monitoring and improved treatment of hypotension in brain-injured patients...
  27. doi request reprint The effect of a change in the surgeon response time mandate on outcomes within Ohio level III trauma centers: it is all about commitment
    Angela Ingraham
    Department of Surgery, University of Cincinnati, Cincinnati, Ohio 45267 0558, USA
    J Trauma 68:1038-43. 2010
    ....
  28. doi request reprint Fondaparinux for prevention of venous thromboembolism in high-risk trauma patients: a pilot study
    Jong Ping Lu
    Department of Surgery, University of California San Francisco, San Francisco, CA
    J Am Coll Surg 209:589-94. 2009
    ..We hypothesized that the occult deep vein thrombosis (DVT) rate in high-risk patients receiving fondaparinux would be <5%...
  29. ncbi request reprint First Trauma Verification Review Committee site visit outside the U.S.: Landstuhl Regional Medical Center, Germany
    M Margaret Knudson
    University of California, San Francisco, USA
    Bull Am Coll Surg 92:16-9. 2007
  30. ncbi request reprint The abdominal compartment syndrome complicating nonoperative management of major blunt liver injuries: recognition and treatment using multimodality therapy
    Edmund Y Yang
    Department of Surgery, University of California, San Francisco 94110, USA
    J Trauma 52:982-6. 2002
  31. ncbi request reprint Surgeons and injury prevention: what you don't know can hurt you!
    M M Knudson
    San Francisco Injury Center, University of California, USA
    J Am Coll Surg 193:119-24. 2001
    ..Advancements in the field of injury control will require efforts to educate medical professionals and the public...
  32. doi request reprint Management of patients with anterior abdominal stab wounds: a Western Trauma Association multicenter trial
    Walter L Biffl
    Department of Surgery, Denver Health Medical Center University of Colorado Denver, Denver, Colorado 80204 4507, USA
    J Trauma 66:1294-301. 2009
    ....
  33. ncbi request reprint Posttraumatic stress symptoms in children after mild to moderate pediatric trauma: a longitudinal examination of symptom prevalence, correlates, and parent-child symptom reporting
    Herbert Schreier
    Department of Psychiatry, Children s Hospital and Research Center at Oakland, Oakland, CA 94110, USA
    J Trauma 58:353-63. 2005
    ....
  34. ncbi request reprint Surgeon-performed bedside organ assessment with sonography after trauma (BOAST): a pilot study from the WTA Multicenter Group
    Grace S Rozycki
    Department of Surgery, Emory University School of Medicine, Grady Memorial Hospital, Atlanta, GA 30303, USA
    J Trauma 59:1356-64. 2005
    ....
  35. ncbi request reprint Lion heart: Saleh Khalef
    M Margaret Knudson
    University of California, San Francisco, USA
    Bull Am Coll Surg 91:27-33. 2006
  36. ncbi request reprint Mental illness as an independent risk factor for unintentional injury and injury recidivism
    Jennifer J Wan
    Department of Surgery at the University of California, San Francisco, California, USA
    J Trauma 61:1299-304. 2006
    ..We hypothesized that diagnosed mental illness is an independent risk factor for unintentional injury and it increases the risk of recidivism...
  37. ncbi request reprint Fractures in access to and assessment of trauma systems
    Mary J Vassar
    San Francisco Injury Center, University of California, San Francisco, San Francisco, CA, USA
    J Am Coll Surg 197:717-25. 2003
    ..This study was undertaken to determine how frequently patients incurring serious trauma in California receive treatment at a trauma center...
  38. ncbi request reprint Blood doping in the surgical intensive care unit
    Jennifer J Wan
    Department of Surgery, University of California, San Francisco East Bay Alameda County Medical Center, Oakland, USA
    Surgery 140:6-8. 2006
  39. ncbi request reprint Profile of mothers at risk: an analysis of injury and pregnancy loss in 1,195 trauma patients
    Danagra G Ikossi
    Department of Surgery, University of California San Francisco, and San Francisco Injury Center, San Francisco, CA 94110, USA
    J Am Coll Surg 200:49-56. 2005
    ..We hypothesized that we could identify women at risk for injury during pregnancy and focus our prevention efforts...
  40. ncbi request reprint Military-civilian collaboration in trauma care and the senior visiting surgeon program
    Ernest E Moore
    Department of Surgery at the Denver Health Medical Center, University of Colorado at Denver, Denver, USA
    N Engl J Med 357:2723-7. 2007
  41. ncbi request reprint Splenic embolization revisited: a multicenter review
    James M Haan
    Department of Surgical Critical Care, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, 22 South Green Street, Baltimore, MD 21201 1595, USA
    J Trauma 56:542-7. 2004
    ..Splenic embolization can increase nonoperative salvage. However, complications are not clearly defined. A retrospective multicenter review was performed to delineate the risks and benefits of splenic embolization...
  42. ncbi request reprint An evaluation of the American College of Surgeons' ultrasound education program
    Edgar D Staren
    Cancer Treatment Centers of America, 2520 Elisha Ave, Zion, IL 60099, USA
    Am J Surg 191:489-96. 2006
    ..The purpose of this study was to evaluate the impact and effectiveness of the ACoS ultrasound education program...
  43. ncbi request reprint Motorcycle helmet laws: every surgeon's responsibility
    M Margaret Knudson
    J Am Coll Surg 199:261-4. 2004

Research Grants3