Robert C Knowlton

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Magnetoencephalography in epilepsy
    Robert C Knowlton
    University of Alabama at Birmingham School of Medicine, UAB Epilepsy Center, Birmingham, Alabama 35294, USA
    Epilepsia 45:61-71. 2004
  2. ncbi request reprint In vivo hippocampal glucose metabolism in mesial temporal lobe epilepsy
    R C Knowlton
    Department of Neurology, University of Alabama at Birmingham, 35294, USA
    Neurology 57:1184-90. 2001
  3. doi request reprint Preference-based quality-of-life measures for neocortical epilepsy surgery
    Robert C Knowlton
    Department of Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294 0001, USA
    Epilepsia 52:1018-20. 2011
  4. pmc Effect of epilepsy magnetic source imaging on intracranial electrode placement
    Robert C Knowlton
    Epilepsy Center, Department of Neurology, University of Alabama at Birmingham, School of Medicine, Birmingham, AL 35294 0001, USA
    Ann Neurol 65:716-23. 2009
  5. doi request reprint Functional imaging: I. Relative predictive value of intracranial electroencephalography
    Robert C Knowlton
    Department of Neurology, University of Alabama at Birmingham Epilepsy Center, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294 0001, USA
    Ann Neurol 64:25-34. 2008
  6. ncbi request reprint Magnetic source imaging versus intracranial electroencephalogram in epilepsy surgery: a prospective study
    Robert C Knowlton
    Department of Neurology, UAB Epilepsy Center, University of Alabama at Birmingham School of Medicine, 35294 0001, USA
    Ann Neurol 59:835-42. 2006
  7. ncbi request reprint The role of FDG-PET, ictal SPECT, and MEG in the epilepsy surgery evaluation
    Robert C Knowlton
    UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
    Epilepsy Behav 8:91-101. 2006
  8. ncbi request reprint Ictal single-photon emission computed tomography imaging in extra temporal lobe epilepsy using statistical parametric mapping
    Robert C Knowlton
    University of Alabama at Birmingham Epilepsy Center, Department of Neurology, School of Medicine, Birmingham, AL 35294, USA
    J Neuroimaging 14:324-30. 2004
  9. ncbi request reprint Ictal SPECT analysis in epilepsy: subtraction and statistical parametric mapping techniques
    Robert C Knowlton
    Department of Neurology, University of Alabama at Birmingham Epilepsy Center, 1719 6th Avenue South, Birmingham, AL 35294, USA
    Neurology 63:10-5. 2004
  10. ncbi request reprint Multimodality imaging in partial epilepsies
    Robert C Knowlton
    UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA
    Curr Opin Neurol 17:165-72. 2004

Research Grants

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Magnetoencephalography in epilepsy
    Robert C Knowlton
    University of Alabama at Birmingham School of Medicine, UAB Epilepsy Center, Birmingham, Alabama 35294, USA
    Epilepsia 45:61-71. 2004
    ..Combined with mapping of normal or eloquent brain function, MEG should ultimately play a major role in the totally noninvasive epilepsy surgery evaluation...
  2. ncbi request reprint In vivo hippocampal glucose metabolism in mesial temporal lobe epilepsy
    R C Knowlton
    Department of Neurology, University of Alabama at Birmingham, 35294, USA
    Neurology 57:1184-90. 2001
    ..Increased partial volume effects due to atrophic hippocampi may further increase appearance of hypometabolism...
  3. doi request reprint Preference-based quality-of-life measures for neocortical epilepsy surgery
    Robert C Knowlton
    Department of Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294 0001, USA
    Epilepsia 52:1018-20. 2011
    ..Seizure freedom achieved with polytherapy medical management may be less desirable than that achieved with surgery and monotherapy...
  4. pmc Effect of epilepsy magnetic source imaging on intracranial electrode placement
    Robert C Knowlton
    Epilepsy Center, Department of Neurology, University of Alabama at Birmingham, School of Medicine, Birmingham, AL 35294 0001, USA
    Ann Neurol 65:716-23. 2009
    ....
  5. doi request reprint Functional imaging: I. Relative predictive value of intracranial electroencephalography
    Robert C Knowlton
    Department of Neurology, University of Alabama at Birmingham Epilepsy Center, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294 0001, USA
    Ann Neurol 64:25-34. 2008
    ....
  6. ncbi request reprint Magnetic source imaging versus intracranial electroencephalogram in epilepsy surgery: a prospective study
    Robert C Knowlton
    Department of Neurology, UAB Epilepsy Center, University of Alabama at Birmingham School of Medicine, 35294 0001, USA
    Ann Neurol 59:835-42. 2006
    ..This study prospectively examined the agreement between magnetic source imaging (MSI) and ICEEG localization in epilepsy surgery candidates...
  7. ncbi request reprint The role of FDG-PET, ictal SPECT, and MEG in the epilepsy surgery evaluation
    Robert C Knowlton
    UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
    Epilepsy Behav 8:91-101. 2006
    ..Ultimately, appropriate use of these tests, combined with more comprehensive functional brain mapping (e.g., with MEG or functional MRI), may lead to completely noninvasive epilepsy surgery evaluation...
  8. ncbi request reprint Ictal single-photon emission computed tomography imaging in extra temporal lobe epilepsy using statistical parametric mapping
    Robert C Knowlton
    University of Alabama at Birmingham Epilepsy Center, Department of Neurology, School of Medicine, Birmingham, AL 35294, USA
    J Neuroimaging 14:324-30. 2004
    ..To examine the application of statistical parametric mapping (SPM) to analyze ictal single-photon emission computed tomography (SPECT) scans in surgical candidates with extratemporal lobe epilepsy...
  9. ncbi request reprint Ictal SPECT analysis in epilepsy: subtraction and statistical parametric mapping techniques
    Robert C Knowlton
    Department of Neurology, University of Alabama at Birmingham Epilepsy Center, 1719 6th Avenue South, Birmingham, AL 35294, USA
    Neurology 63:10-5. 2004
    ..The limitations of both methodologies are discussed, and suggestions for further study of validation, improvement, and routine clinical implementation of advanced analysis methods are provided...
  10. ncbi request reprint Multimodality imaging in partial epilepsies
    Robert C Knowlton
    UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA
    Curr Opin Neurol 17:165-72. 2004
    ....
  11. ncbi request reprint Magnetoencephalography: clinical application in epilepsy
    Robert C Knowlton
    UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham School of Medicine, 1719 6th Avenue South, Suite 312, Birmingham, AL 35294, USA
    Curr Neurol Neurosci Rep 3:341-8. 2003
    ..Ultimately, MEG should play a major role in totally noninvasive epilepsy surgery evaluation...
  12. ncbi request reprint In vivo hippocampal metabolic dysfunction in human temporal lobe epilepsy
    Robert C Knowlton
    UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham School of Medicine, 35294 0021, USA
    Arch Neurol 59:1882-6. 2002
    ..The nature of functional metabolic disturbances in mesial temporal lobe epilepsy remains unclear...
  13. doi request reprint Functional imaging: II. Prediction of epilepsy surgery outcome
    Robert C Knowlton
    UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham, School of Medicine, Birmingham, AL 35294 0001, USA
    Ann Neurol 64:35-41. 2008
    ....
  14. pmc Short latency activation of cortex by clinically effective thalamic brain stimulation for tremor
    Harrison C Walker
    Department of Neurology, University of Alabama Birmingham, Birmingham, Alabama, USA
    Mov Disord 27:1404-12. 2012
    ....
  15. pmc Multimodal analysis of the hippocampus in schizophrenia using proton magnetic resonance spectroscopy and functional magnetic resonance imaging
    Nathan L Hutcheson
    Department of Psychiatry and Behavioral Neurobiology, The University of Alabama at Birmingham, Birmingham, AL, USA
    Schizophr Res 140:136-42. 2012
    ..In this study, we combined proton magnetic resonance spectroscopy (¹H-MRS) and functional magnetic resonance imaging (fMRI) to clarify the neurobiology of memory deficits in schizophrenia...
  16. ncbi request reprint Musicogenic seizures can arise from multiple temporal lobe foci: intracranial EEG analyses of three patients
    Tania F Tayah
    Department of Neurology, Vanderbilt University, Nashville, Tennessee 37232 8552, USA
    Epilepsia 47:1402-6. 2006
    ..To determine the ictal-onset zone of musicogenic seizures by using intracranial EEG monitoring...
  17. ncbi request reprint Temporal lobectomy in congenital porencephaly associated with hippocampal sclerosis
    Jorge G Burneo
    Department of Neurology, Epilepsy Center, University of Alabama at Birmingham, 35294, USA
    Arch Neurol 60:830-4. 2003
    ..Clinical and neuroimaging features of patients with epilepsy and coexisting extratemporal porencephaly and hippocampal sclerosis have been previously described...
  18. ncbi request reprint Significance of fornix atrophy in temporal lobe epilepsy surgery outcome
    Jorge G Burneo
    University of Alabama at Birmingham Epilepsy Center, and the Department of Neurology and Neurosurgery, University of Alabama at Birmingham, 35294, USA
    Arch Neurol 60:1238-42. 2003
    ..The contribution of the fornix as an independent preoperative determinant of surgical outcome is unknown...
  19. ncbi request reprint Reliability of language mapping with magnetic source imaging in epilepsy surgery candidates
    Dongwook Lee
    Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA
    Epilepsy Behav 8:742-9. 2006
    ..The results further support the adequacy of this MEG-based brain mapping protocol as a noninvasive tool for receptive language localization in epilepsy surgery candidates...
  20. ncbi request reprint Dynamic brain activation patterns for face recognition: a magnetoencephalography study
    Dongwook Lee
    Department of Neurology, University of Alabama, Birmingham, AL 35233, USA
    Brain Topogr 18:19-26. 2005
    ..The results indicate right hemisphere predominance in the degree of engagement of neurophysiological processes involved in both the pre- and post-recognition phases of face processing...
  21. ncbi request reprint Cortical reorganization in malformations of cortical development: a magnetoencephalographic study
    Jorge G Burneo
    University of Alabama at Birmingham Epilepsy Center, USA
    Neurology 63:1818-24. 2004
    ..Magnetoencephalography (MEG) source localization of evoked fields can address whether functional reorganization of primary sensory modalities exists in MCDs...
  22. doi request reprint Left mesial temporal sclerosis and verbal memory: a magnetoencephalography study
    Lawrence W Ver Hoef
    University of Alabama Epilepsy Center, Department of Neurology, Birmingham, Alabama, USA
    J Clin Neurophysiol 25:1-6. 2008
    ..A trend toward less left mesial temporal activity in LMTS patients is seen as well. Further study is needed to determine the predictive value of this technique regarding postresection memory outcome...
  23. doi request reprint Advances in intracranial monitoring
    Jeffrey P Blount
    Comprehensive Epilepsy Center, University of Alabama at Birmingham, Alabama 35233, USA
    Neurosurg Focus 25:E18. 2008
    ..Each form has its own advantages and shortcomings but extensive subdural implantation of electrodes is most common and is most comprehensively discussed. The indications for intracranial electrodes are reviewed...
  24. ncbi request reprint Confirmation of nonconvulsive limbic status epilepticus with the sodium amytal test
    Jorge G Burneo
    Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Epilepsia 44:1122-6. 2003
    ..We present the case of a patient who had dominant limbic hippocampal SE, but in whom the diagnosis could not be confirmed until a modified novel use of the sodium amytal test was performed...
  25. doi request reprint Effect of detection parameters on automated electroencephalography spike detection sensitivity and false-positive rate
    Lawrence Ver Hoef
    UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Clin Neurophysiol 27:12-6. 2010
    ..The authors report sensitivities and false-positive rates for several different sets of detection parameters...
  26. pmc Assessments of function and biochemistry of the anterior cingulate cortex in schizophrenia
    Meredith A Reid
    Department of Psychiatry and Behavioral Neurobiology, University of Alabama, Birmingham, Alabama 35294 0017, USA
    Biol Psychiatry 68:625-33. 2010
    ..In this study, we sought to clarify the nature of this abnormality by combining proton magnetic resonance spectroscopy (1H-MRS) with functional magnetic resonance imaging (fMRI) at 3T...
  27. pmc Evaluating hippocampal internal architecture on MRI: Inter-rater reliability of a proposed scoring system
    Lawrence W Ver Hoef
    UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, United States Neurology Service, Birmingham VA Medical Center, Birmingham, AL, United States Electronic address
    Epilepsy Res 106:146-54. 2013
    ..We propose a visual scoring system that rates HIA clarity from 1 (imperceptible) to 4 (excellent) and report the inter-rater reliability (IRR) of this system...
  28. pmc Short latency activation of cortex during clinically effective subthalamic deep brain stimulation for Parkinson's disease
    Harrison C Walker
    Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0017, USA
    Mov Disord 27:864-73. 2012
    ....
  29. ncbi request reprint Evolving antiepileptic drug treatment in juvenile myoclonic epilepsy
    Avinash Prasad
    Epilepsy Division, Department of Neurology, University of Alabama School of Medicine, 312 Civitan International Research Center, 1719 Sixth Avenue, Birmingham, AL 35492, USA
    Arch Neurol 60:1100-5. 2003
    ..In the face of availability of newer antiepileptic drugs (AEDs) such as lamotrigine and topiramate, there is need to reassess the role of older AEDs in the treatment of juvenile myoclonic epilepsy (JME)...
  30. ncbi request reprint Neuroimaging of epilepsy
    Ruben I Kuzniecky
    UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Semin Neurol 22:279-88. 2002
    ..New developments such as MR spectroscopy, receptor PET, and magnetic source imaging are becoming clinical tools and have the promise of improving diagnosis...
  31. doi request reprint Hyperammonemia following intravenous valproate loading
    Jennifer L DeWolfe
    University of Alabama at Birmingham Epilepsy Center, Department of Neurology, 1719 6th Avenue South, CIRC 312, Birmingham, AL 35294 0021, United States
    Epilepsy Res 85:65-71. 2009
    ..Valproic acid (VPA) has been associated with hyperammonemia with and without encephalopathy. We report the frequent but transient nature of hyperammonemia following intravenous (IV) administration of loading doses of VPA...
  32. ncbi request reprint Dexmedetomidine as rescue drug during awake craniotomy for cortical motor mapping and tumor resection
    Thomas A Moore
    Department of Anesthesiology, University of Alabama School of Medicine, Birmingham, Alabama 35249 6810, USA
    Anesth Analg 102:1556-8. 2006
    ..Herein, we describe the use of dexmedetomidine as a rescue drug during awake craniotomy avoiding conversion to general anesthesia, thus allowing completion of cortical mapping...
  33. pmc Smaller regional gray matter volume in homeless african american cocaine-dependent men: a preliminary report
    Rosalyn E Weller
    Department of Psychology, University of Alabama at Birmingham UAB, Birmingham, AL, London
    Open Neuroimag J 5:57-64. 2011
    ..Reduced gray matter in executive function/inhibitory control regions of the brain in cocaine-dependent individuals may be a preexisting risk factor for the development of addiction and/or a consequence of drug abuse...
  34. doi request reprint Widespread reward-system activation in obese women in response to pictures of high-calorie foods
    Luke E Stoeckel
    Department of Psychology, University of Alabama at Birmingham, Birmingham, AL 35294 1170, USA
    Neuroimage 41:636-47. 2008
    ..In summary, compared to normal-weight controls, obese women exhibited greater activation in response to pictures of high-calorie foods in a large number of regions hypothesized to mediate motivational effects of food cues...
  35. doi request reprint Predictive value of hippocampal internal architecture asymmetry in temporal lobe epilepsy
    Lawrence W Ver Hoef
    UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, United States Neurology Service, Birmingham VA Medical Center, Birmingham, AL, United States Electronic address
    Epilepsy Res 106:155-63. 2013
    ....
  36. ncbi request reprint Race/ethnicity: a predictor of temporal lobe epilepsy surgery outcome?
    Jorge G Burneo
    Epilepsy Programme, University of Western Ontario, London, Canada
    Epilepsy Behav 7:486-90. 2005
    ..Nonetheless, whether race influences the outcome of temporal lobe surgery is unknown. The purpose of this study was to evaluate if race plays a role in outcome following surgery...
  37. ncbi request reprint Electroclinical and magnetoencephalographic studies in epilepsy patients with polymicrogyria
    Jorge G Burneo
    Epilepsy Programme, London Health Sciences Center, University of Western Ontario, 339 Windermere Road, London, Ontario, Canada N6A 5A5
    Epilepsy Res 62:125-33. 2004
    ..The present descriptive study analysis the electroclinical and magnetoencephalographic findings of patients with epilepsy and polymicrogyria without schizencephaly...
  38. ncbi request reprint Kaplan-Meier analysis on seizure outcome after epilepsy surgery: do gender and race influence it?
    Jorge G Burneo
    Epilepsy Programme, University of Western Ontario, London Health Science Center, 339 Windermere Road, London, Ontario, Canada
    Seizure 17:314-9. 2008
    ..To evaluate seizure outcome following epilepsy surgery for patients with temporal lobe epilepsy and evaluate is gender and race/ethnicity influence it...
  39. ncbi request reprint Race/ethnicity, sex, and socioeconomic status as predictors of outcome after surgery for temporal lobe epilepsy
    Jorge G Burneo
    Epilepsy Programme, University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada
    Arch Neurol 63:1106-10. 2006
    ..Several risk factors have been attributed to seizure recurrence after surgery. It is unknown whether race/ethnicity plays a role in outcome...
  40. pmc Design and applications of a multimodality image data warehouse framework
    Stephen T C Wong
    Department of Radiology, University of California San Francisco, 94143, USA
    J Am Med Inform Assoc 9:239-54. 2002
    ..The image data warehouse framework can be modified and generalized for new application domains...

Research Grants1

  1. ROLE OF FDG-PET, 1H-MRSI, AND MSI IN EPILEPSY SURGERY
    Robert Knowlton; Fiscal Year: 2005
    ....