Research Topics
| S KnightSummaryAffiliation: University of Utah Country: USA Publications
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Detail Information
Publications
Evaluation of genetic risk scores for lipid levels using genome-wide markers in the Framingham Heart StudyStephen R Piccolo
Department of Biomedical Informatics, School of Medicine, University of Utah, 26 South 2000 East, Salt Lake City, Utah 84112, USA
BMC Proc 3:S46. 2009..In this paper, we evaluate a weighted and an unweighted approach for estimating the combined effect of multiple markers (using genotypes and haplotypes) on lipid levels for a given individual...
Shared genomic segment analysis: the power to find rare disease variantsStacey Knight
Division of Genetic Epidemiology, University of Utah School of Medicine, Salt Lake City, UT 84108, USA
Ann Hum Genet 76:500-9. 2012..96 Mb region containing the known causal APC gene with genome-wide significance. SGS is a powerful method for detecting rare variants and a valuable complement to genome-wide association studies and linkage analysis...- Health insurance, neighborhood income, and emergency department usage by Utah children 1996-1998Anthony Suruda
Intermountain Injury Control Research Center, University of Utah, 615 Arapeen Drive 202, Salt Lake City, Utah 84108, USA
BMC Health Serv Res 5:29. 2005..We examined pediatric ED usage in a U.S. state with respect to income, health insurance status, types of medical conditions, and whether introduction of managed care affected utilization by Medicaid children... - Validity and power of association testing in family-based sampling designs: evidence for and against the common wisdomStacey Knight
Division of Genetic Epidemiology, Salt Lake City, Utah, USA
Genet Epidemiol 35:174-81. 2011..These results suggest a more complex situation than previously assumed, which has important implications for study design and analysis... - Pedigree association: assigning individual weights to pedigree members for genetic association analysisStacey Knight
Biomedical Informatics Department, University of Utah, 26 South 2000 East Room 5775 HSEB, Salt Lake City, Utah 84112, USA
BMC Proc 3:S121. 2009..We compare this new method with an existing weighting algorithm, a naïve analysis (relatedness is ignored), and an empirical method that appropriately accounts for all relationships (the gold standard)... - Summary of contributions to GAW Group 15: family-based samples are useful in identifying common polymorphisms associated with complex traitsStacey Knight
Biomedical Informatics Department, University of Utah, Salt Lake City, Utah 84108, USA
Genet Epidemiol 33:S99-104. 2009..Our findings highlight the contribution of family-based samples to the genetic dissection of complex traits... - Linkage analysis of Tourette syndrome in a large Utah pedigreeStacey Knight
Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, USA
Am J Med Genet B Neuropsychiatr Genet 153:656-62. 2010..03). The significant linkage peaks on chromosomes 1p and 3p are in new areas of the genome for TS, and replication of these findings is necessary... 
Prehospital emergency care for children at school and nonschool locationsS Knight
Intermountain Injury Control Research Center, University of Utah, Salt Lake City, UT 84108, USA
Pediatrics 103:e81. 1999..The purpose of this study was to ascertain whether school-based emergency medical services (EMS) incidents are different from nonschool-based EMS incidents for school-aged children...- The fast and the fatal: street racing fatal crashes in the United StatesS Knight
Intermountain Injury Control Research Center, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, 84108, USA
Inj Prev 10:53-5. 2004..Compared with other drivers involved in fatal crashes, street racers were more likely to be teenagers, male, and have previous crashes and driving violations. Street racing involves risky driving behaviors and warrants further attention... - Shoulder belts in motor vehicle crashes: a statewide analysis of restraint efficacyS Knight
Intermountain Injury Control Research Center, University of Utah, Salt Lake City 84108, USA
Accid Anal Prev 33:65-71. 2001..1; 95% Cl = 0.9, 1.4). Average hospital inpatient length of stay, charges and injury severity scores were similar for all restraint types. These results stress the need for the use of a lap belt in conjunction with the shoulder belt... - Injuries sustained by students in shop classS Knight
Intermountain Injury Control Research Center, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
Pediatrics 106:10-3. 2000..The purpose of our study was to describe the epidemiology of shop class injuries in Utah public schools for the years 1992-1996... - Against all advice: an analysis of out-of-hospital refusals of careStacey Knight
Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA
Ann Emerg Med 42:689-96. 2003.... - Motor vehicle crash characteristics and medical outcomes among older drivers in Utah, 1992-1995L J Cook
University of Utah School of Medicine, Department of Pediatrics, The Intermountain Injury Control Research Center, Salt Lake City, UT, USA
Ann Emerg Med 35:585-91. 2000..We sought to compare the characteristics and medical outcomes of motor vehicle crashes for drivers 70 years and older with those of drivers between the ages of 30 and 39 years... - Analysis of school injuries resulting in emergency department or hospital admissionE P Junkins
Division of Pediatric Emergency Medicine, Division of Critical Care Medicine, Primary Children s Medical Center, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT 84113, USA
Acad Emerg Med 8:343-8. 2001..To describe the epidemiology of school injuries resulting in emergency department (ED) visits, hospital admission, or death... - The sumLINK statistic for genetic linkage analysis in the presence of heterogeneityG B Christensen
Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, Utah 84108 1266, USA
Genet Epidemiol 33:628-36. 2009..Further, loci identified with the sumLINK have good potential for gene localization via statistical recombinant mapping, as, by definition, several linked pedigrees contribute to each peak... - Multicenter cohort study of out-of-hospital pediatric cardiac arrestFrank W Moler
Pediatric Emergency Care Applied Research Network, Salt Lake City, UT, USA
Crit Care Med 39:141-9. 2011..These objectives were for planning an interventional trial of therapeutic hypothermia after pediatric cardiac arrest... - Factors associated with cervical spine injury in children after blunt traumaJulie C Leonard
Department of Pediatrics, Division of Emergency Medicine, School of Medicine, Washington University in St Louis, St Louis Children s Hospital, One Children s Place, St Louis, MO 63110, USA
Ann Emerg Med 58:145-55. 2011..The purpose of our study is to identify risk factors associated with cervical spine injury in children after blunt trauma... - Epidemiology of psychiatric-related visits to emergency departments in a multicenter collaborative research pediatric networkPrashant Mahajan
Division of Emergency Medicine, Department of Pediatrics, Children s Hospital of Michigan and Wayne State University, 3901 Beaubien, Detroit, MI 48201, USA
Pediatr Emerg Care 25:715-20. 2009..Describe the epidemiology of pediatric psychiatric-related visits to emergency departments participating in the Pediatric Emergency Care Applied Research Network... - Intracranial hemorrhage after blunt head trauma in children with bleeding disordersLois K Lee
Department of Pediatrics, Harvard Medical School, Boston, MA, USA
J Pediatr 158:1003-1008.e1-2. 2011..To determine computerized tomography (CT) use and prevalence of traumatic intracranial hemorrhage (ICH) in children with and without congenital and acquired bleeding disorders... - The use of generalized estimating equations in the analysis of motor vehicle crash dataCaroline B Hutchings
Intermountain Injury Control Research Center, School of Medicine, University of Utah, 615 Arapeen Drive, Suite 202, 84108, Salt Lake City, UT 84108, USA
Accid Anal Prev 35:3-8. 2003..The odds ratio of seat belt effectiveness in preventing injuries was 12% lower when a one-level nested model was used. Based on these results, we stress the need to use a nested model and GEEs when analyzing motor vehicle crash data... - Repeat patients to the emergency department in a statewide databaseLawrence J Cook
Intermountain Injury Control Research Center, University of Utah School of Medicine, Department of Pediatrics, Salt Lake City, UT, USA
Acad Emerg Med 11:256-63. 2004..To describe the epidemiology of repeat users of the emergency department (ED) using a statewide database... - Prediction of child abuse risk from emergency department useElisabeth Guenther
Division of Pediatric Emergency Medicine, University of Utah Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT 84158, USA
J Pediatr 154:272-7. 2009..To examine whether pre-abuse rates and patterns of emergency department (ED) visits between children with supported child abuse and age-matched control subjects are useful markers for abuse risk... - Graduated driver licensing in Utah: is it effective?Lisa K Hyde
Intermountain Injury Control Research Center, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT 84108, USA
Ann Emerg Med 45:147-54. 2005..We seek to examine the effectiveness of the graduated driver licensing system in Utah by determining whether crash rates of 16-year-old drivers decreased after graduated driver licensing implementation... - Underestimating injury mortality using statewide databasesN Clay Mann
Intermountain Injury Control Research Center, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
J Trauma 58:162-7. 2005.... - A comparison of aggressive and DUI crashesLawrence J Cook
University of Utah School of Medicine, Department of Pediatrics, Utah CODES, The Intermountain Injury Control Research Center, University of Utah, 295 Chipeta Way, P.O. Box 581289, Salt Lake City, UT 84158-1289, USA
J Safety Res 36:491-3. 2005 - Automated construction and testing of multi-locus gene-gene associationsRyan Abo
Department of Biomedical Informatics, University of Utah School of Medicine, UT, USA
Bioinformatics 27:134-6. 2011..This tool provides a flexible data-mining approach to identifying gene-gene effects that otherwise is currently unavailable. AVAILABILITY: http://bioinformatics.med.utah.edu/Genie/hapConstructor.html... - Modeling motor vehicle crashes for street racers using zero-inflated modelsZhuo Li
Department of Family and Preventive Medicine, University of Utah, 375 Chipeta Way, Salt Lake City, UT 84108, USA
Accid Anal Prev 40:835-9. 2008..However, drivers with increased numbers of non-street-racing citations experience crash risks approaching those of the cited street racers... - Classroom injuries in Utah public schoolsMichael D Kramer
Department of Pediatrics, and Intermountain Injury Control Research Center, University of Utah School of Medicine, Salt Lake City 84108, USA
Acad Emerg Med 10:978-84. 2003..School injuries are a serious public health problem, yet classroom injuries have received little attention. The purpose of this study was to describe the epidemiology of classroom injuries in Utah public schools... - hapConstructor: automatic construction and testing of haplotypes in a Monte Carlo frameworkRyan Abo
Department of Biomedical Informatics, University of Utah, UT, USA
Bioinformatics 24:2105-7. 2008..HapConstructor is a useful tool for exploring multi-locus associations in candidate genes and regions. AVAILABILITY: http://www-genepi.med.utah.edu/Genie... - Emergency department quality: an analysis of existing pediatric measuresEvaline Alessandrini
Department of Pediatrics, University of Cincinnati College of Medicine, James M Anderson Center for Health Systems Excellence, Cincinnati Children s Hospital Medical Center EA, KV, OH, USA
Acad Emerg Med 18:519-26. 2011..The authors undertook this study with the goals of enumerating and categorizing existing performance measures relevant to pediatric emergency care... - Lack of agreement in pediatric emergency department discharge diagnoses from clinical and administrative data sourcesMarc H Gorelick
Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA
Acad Emerg Med 14:646-52. 2007..Diagnosis information from existing data sources is used commonly for epidemiologic, administrative, and research purposes. The quality of such data for emergency department (ED) visits is unknown... - Revisiting the emergency medicine services for children research agenda: priorities for multicenter research in pediatric emergency careSteven Zane Miller
Department of Pediatrics, Division of Pediatric Emergency Medicine, Morgan Stanley Children s Hospital of New York Presbyterian, Columbia University Medical Center, New York, NY, USA
Acad Emerg Med 15:377-83. 2008..They sought to prioritize PECARN research efforts, to guide investigators planning to conduct research in PECARN, and to describe the creation of a prioritized EMSC research agenda specific for multicenter research... - Interobserver agreement in assessment of clinical variables in children with blunt head traumaMarc H Gorelick
Department of Pediatrics, Section of Emergency Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
Acad Emerg Med 15:812-8. 2008..The objective was to determine the interobserver agreement in the assessment of historical and physical examination findings of children undergoing emergency department (ED) evaluation for blunt head trauma... - Epidemiology of a pediatric emergency medicine research network: the PECARN Core Data ProjectElizabeth R Alpern
Department of Pediatrics, Division of Emergency Medicine, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Pediatr Emerg Care 22:689-99. 2006..To examine the epidemiology of pediatric patient visits to emergency departments (ED)... - Perceived challenges to obtaining informed consent for a time-sensitive emergency department study of pediatric status epilepticus: results of two focus groupsJames M Chamberlain
Department of Pediatrics, George Washington University School of Medicine and Health Sciences, Children s National Medical Center, Washington, DC, USA
Acad Emerg Med 16:763-70. 2009..The objective was to describe the perspective of research personnel on issues of informed consent in a time-sensitive clinical study under emergency circumstances...