M W Klymkowsky

Summary

Affiliation: University of Colorado
Country: USA

Publications

  1. pmc Teaching without a textbook: strategies to focus learning on fundamental concepts and scientific process
    M W Klymkowsky
    The Bioliteracy Project Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Boulder, CO 80309 0347, USA
    CBE Life Sci Educ 6:190-3. 2007
  2. ncbi request reprint Plakophilin, armadillo repeats, and nuclear localization
    M W Klymkowsky
    Molecular, Cellular and Developmental Biology, University of Colorado, Boulder 80309 0347, USA
    Microsc Res Tech 45:43-54. 1999
  3. pmc Membrane-anchored plakoglobins have multiple mechanisms of action in Wnt signaling
    M W Klymkowsky
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Boulder, Colorado, 80309 0347, USA
    Mol Biol Cell 10:3151-69. 1999
  4. ncbi request reprint SOX7 is an immediate-early target of VegT and regulates Nodal-related gene expression in Xenopus
    Chi Zhang
    Molecular, Cellular and Developmental Biology, University of Colorado, Porter Biosci Building, Boulder, CO 80309 0347, USA
    Dev Biol 278:526-41. 2005
  5. ncbi request reprint Cadherins and catenins, Wnts and SOXs: embryonic patterning in Xenopus
    A L St Amand
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder 80309, USA
    Int Rev Cytol 203:291-355. 2001
  6. ncbi request reprint The beta-catenin/VegT-regulated early zygotic gene Xnr5 is a direct target of SOX3 regulation
    Chi Zhang
    Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, Colorado 80309 0347, USA
    Development 130:5609-24. 2003
  7. ncbi request reprint Embryonic expression of Xenopus laevis SOX7
    Shana R Fawcett
    Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA
    Gene Expr Patterns 4:29-33. 2004
  8. pmc Jaw muscle development as evidence for embryonic repatterning in direct-developing frogs
    J Hanken
    Department of Environmental, Population, and Organismic Biology, University of Colorado, Boulder 80309 0334, USA
    Proc Biol Sci 264:1349-54. 1997
  9. ncbi request reprint The body language of cells: the intimate connection between cell adhesion and behavior
    M W Klymkowsky
    University of Colorado, Boulder, Colorado 80309 0347, USA
    Cell 83:5-8. 1995
  10. ncbi request reprint The appearance of acetylated alpha-tubulin during early development and cellular differentiation in Xenopus
    D T Chu
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder 80309 0347
    Dev Biol 136:104-17. 1989

Collaborators

Detail Information

Publications13

  1. pmc Teaching without a textbook: strategies to focus learning on fundamental concepts and scientific process
    M W Klymkowsky
    The Bioliteracy Project Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Boulder, CO 80309 0347, USA
    CBE Life Sci Educ 6:190-3. 2007
    ....
  2. ncbi request reprint Plakophilin, armadillo repeats, and nuclear localization
    M W Klymkowsky
    Molecular, Cellular and Developmental Biology, University of Colorado, Boulder 80309 0347, USA
    Microsc Res Tech 45:43-54. 1999
    ..Based on these types of experiments, GFP can be seen as a marker of the distribution of the mature form of the tagged polypeptide...
  3. pmc Membrane-anchored plakoglobins have multiple mechanisms of action in Wnt signaling
    M W Klymkowsky
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Boulder, Colorado, 80309 0347, USA
    Mol Biol Cell 10:3151-69. 1999
    ..Based on these data, we conclude that, in addition to its effects on beta-catenin, cnxPg interacts with other components of the Wnt pathway, perhaps TCFs, and that these interactions contribute to its signaling activity...
  4. ncbi request reprint SOX7 is an immediate-early target of VegT and regulates Nodal-related gene expression in Xenopus
    Chi Zhang
    Molecular, Cellular and Developmental Biology, University of Colorado, Porter Biosci Building, Boulder, CO 80309 0347, USA
    Dev Biol 278:526-41. 2005
    ..2004. Dev. Biol. 273, 23) and their common binding sites in the Xnr5 promoter, we propose a model in which competitive interactions between these two proteins are involved in refining the domain of endodermal differentiation...
  5. ncbi request reprint Cadherins and catenins, Wnts and SOXs: embryonic patterning in Xenopus
    A L St Amand
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder 80309, USA
    Int Rev Cytol 203:291-355. 2001
    ..We review this literature, focusing on the role of Wnt signaling and interacting components in establishing patterns within the early embryo...
  6. ncbi request reprint The beta-catenin/VegT-regulated early zygotic gene Xnr5 is a direct target of SOX3 regulation
    Chi Zhang
    Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, Colorado 80309 0347, USA
    Development 130:5609-24. 2003
    ..These observations indicate that maternal XSOX3 acts in a novel manner to restrict Xnr5 expression to the vegetal hemisphere...
  7. ncbi request reprint Embryonic expression of Xenopus laevis SOX7
    Shana R Fawcett
    Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA
    Gene Expr Patterns 4:29-33. 2004
    ..XSOX7 expression continues within the hindbrain in 3-day old ( approximately stage 40) larvae. Given its widespread expression, XSOX7 is likely to be involved in a number of developmental processes...
  8. pmc Jaw muscle development as evidence for embryonic repatterning in direct-developing frogs
    J Hanken
    Department of Environmental, Population, and Organismic Biology, University of Colorado, Boulder 80309 0334, USA
    Proc Biol Sci 264:1349-54. 1997
    ..Such mechanisms may also facilitate, in organisms with a primitively complex life cycle, the evolutionary dissociation of embryonic, larval, and adult features...
  9. ncbi request reprint The body language of cells: the intimate connection between cell adhesion and behavior
    M W Klymkowsky
    University of Colorado, Boulder, Colorado 80309 0347, USA
    Cell 83:5-8. 1995
  10. ncbi request reprint The appearance of acetylated alpha-tubulin during early development and cellular differentiation in Xenopus
    D T Chu
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder 80309 0347
    Dev Biol 136:104-17. 1989
    ..The changing pattern of anti-acetylated tubulin staining during Xenopus development raises intriguing questions as to the physiological significance of tubulin acetylation...
  11. pmc Thinking about the conceptual foundations of the biological sciences
    M W Klymkowsky
    University of Colorado Boulder, 80309 0347, USA
    CBE Life Sci Educ 9:405-7. 2010
    ..Not until the core concepts of biology are clearly defined and become the focus of instruction and assessment can we expect meaningful improvements in biological literacy and the removal of unnecessary barriers to student engagement...
  12. ncbi request reprint Mitochondrial activity, embryogenesis, and the dialogue between the big and little brains of the cell
    M W Klymkowsky
    Molecular, Cellular and Developmental Biology and CU Teach, University of Colorado, Boulder, Boulder, CO 80309 0347, USA
    Mitochondrion 11:814-9. 2011
    ..g. β-catenin, NF-κB, p53, and STAT3, have been found to localize to mitochondria...