Yann C Klimentidis

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc Natural selection at genomic regions associated with obesity and type-2 diabetes: East Asians and sub-Saharan Africans exhibit high levels of differentiation at type-2 diabetes regions
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, 1665 University Blvd, RPHB 327, Birmingham, AL 35294, USA
    Hum Genet 129:407-18. 2011
  2. pmc Genetic admixture, social-behavioural factors and body composition are associated with blood pressure differently by racial-ethnic group among children
    Y C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Hum Hypertens 26:98-107. 2012
  3. pmc Ancestry-informative markers on chromosomes 2, 8 and 15 are associated with insulin-related traits in a racially diverse sample of children
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA
    Hum Genomics 5:79-89. 2011
  4. pmc Natural selection among Eurasians at genomic regions associated with HIV-1 control
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Evol Biol 11:173. 2011
  5. pmc Prediction of expected years of life using whole-genome markers
    Gustavo de Los Campos
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 7:e40964. 2012
  6. doi request reprint A unified GMDR method for detecting gene-gene interactions in family and unrelated samples with application to nicotine dependence
    Guo Bo Chen
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, 1665 University Boulevard, RPHB 327, Birmingham, AL, 35294 0022, USA
    Hum Genet 133:139-50. 2014
  7. pmc Prediction of complex human traits using the genomic best linear unbiased predictor
    Gustavo de Los Campos
    Biostatistics Department, University of Alabama at Birmingham, Birmingham, Alabama, USA
    PLoS Genet 9:e1003608. 2013
  8. pmc A comprehensive genetic approach for improving prediction of skin cancer risk in humans
    Ana I Vazquez
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama, Birmingham, AL 35294, USA
    Genetics 192:1493-502. 2012
  9. pmc Associations of obesity genes with obesity-related outcomes in multiethnic children
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, 1530 Third Avenue South, Birmingham, AL 35294 3360, USA
    Arch Med Res 42:509-14. 2011
  10. pmc Beyond missing heritability: prediction of complex traits
    Robert Makowsky
    Department of Biostatistics, University of Alabama at Birmingham, Alabama, United States of America
    PLoS Genet 7:e1002051. 2011

Detail Information

Publications13

  1. pmc Natural selection at genomic regions associated with obesity and type-2 diabetes: East Asians and sub-Saharan Africans exhibit high levels of differentiation at type-2 diabetes regions
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, 1665 University Blvd, RPHB 327, Birmingham, AL 35294, USA
    Hum Genet 129:407-18. 2011
    ..Our findings suggest that there is an evolutionary genetic basis for population differences in these traits, and we have identified potential group-specific genetic risk factors...
  2. pmc Genetic admixture, social-behavioural factors and body composition are associated with blood pressure differently by racial-ethnic group among children
    Y C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Hum Hypertens 26:98-107. 2012
    ....
  3. pmc Ancestry-informative markers on chromosomes 2, 8 and 15 are associated with insulin-related traits in a racially diverse sample of children
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA
    Hum Genomics 5:79-89. 2011
    ..Importantly, we have implicated this region in the early development of diabetes-related phenotypes, and in the genetic aetiology of population differences in these phenotypes...
  4. pmc Natural selection among Eurasians at genomic regions associated with HIV-1 control
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Evol Biol 11:173. 2011
    ....
  5. pmc Prediction of expected years of life using whole-genome markers
    Gustavo de Los Campos
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 7:e40964. 2012
    ....
  6. doi request reprint A unified GMDR method for detecting gene-gene interactions in family and unrelated samples with application to nicotine dependence
    Guo Bo Chen
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, 1665 University Boulevard, RPHB 327, Birmingham, AL, 35294 0022, USA
    Hum Genet 133:139-50. 2014
    ....
  7. pmc Prediction of complex human traits using the genomic best linear unbiased predictor
    Gustavo de Los Campos
    Biostatistics Department, University of Alabama at Birmingham, Birmingham, Alabama, USA
    PLoS Genet 9:e1003608. 2013
    ..We show how PA can be enhanced with use of variable selection or differential shrinkage of estimates of marker effects. ..
  8. pmc A comprehensive genetic approach for improving prediction of skin cancer risk in humans
    Ana I Vazquez
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama, Birmingham, AL 35294, USA
    Genetics 192:1493-502. 2012
    ..We discuss avenues for improving prediction accuracy and speculate on the possible use of WGP to prospectively identify individuals at high risk...
  9. pmc Associations of obesity genes with obesity-related outcomes in multiethnic children
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, 1530 Third Avenue South, Birmingham, AL 35294 3360, USA
    Arch Med Res 42:509-14. 2011
    ....
  10. pmc Beyond missing heritability: prediction of complex traits
    Robert Makowsky
    Department of Biostatistics, University of Alabama at Birmingham, Alabama, United States of America
    PLoS Genet 7:e1002051. 2011
    ..While such R(2) values vastly exceed what has been previously reported using a reduced number of pre-selected markers (<0.10), given the heritability of the trait (∼ 0.80), substantial room for improvement remains...
  11. pmc Canaries in the coal mine: a cross-species analysis of the plurality of obesity epidemics
    Yann C Klimentidis
    Department of Biostatistics, University of Alabama, Birmingham, AL, USA
    Proc Biol Sci 278:1626-32. 2011
    ..g. viral pathogens, epigenetic factors). This finding may eventually enhance the discovery and fuller elucidation of other factors that have contributed to the recent rise in obesity rates...
  12. pmc A conserved role for syndecan family members in the regulation of whole-body energy metabolism
    Maria De Luca
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 5:e11286. 2010
    ..035) and intra-abdominal fat (P = 0.049), and SNP rs2267871 with insulin sensitivity (P = 0.037). Collectively, our results in Drosophila and humans argue that syndecan family members play a key role in the regulation of body metabolism...
  13. pmc Evidence for novel genetic loci associated with metabolic traits in Yup'ik people
    Stella Aslibekyan
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, 35294
    Am J Hum Biol 25:673-80. 2013
    ....