Research Topics
Species | Yann C KlimentidisSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Publications
Natural selection at genomic regions associated with obesity and type-2 diabetes: East Asians and sub-Saharan Africans exhibit high levels of differentiation at type-2 diabetes regionsYann C Klimentidis
Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, 1665 University Blvd, RPHB 327, Birmingham, AL 35294, USA
Hum Genet 129:407-18. 2011..Our findings suggest that there is an evolutionary genetic basis for population differences in these traits, and we have identified potential group-specific genetic risk factors...- Genetic admixture, social-behavioural factors and body composition are associated with blood pressure differently by racial-ethnic group among childrenY C Klimentidis
Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Hum Hypertens 26:98-107. 2012.... - Ancestry-informative markers on chromosomes 2, 8 and 15 are associated with insulin-related traits in a racially diverse sample of childrenYann C Klimentidis
Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA
Hum Genomics 5:79-89. 2011..Importantly, we have implicated this region in the early development of diabetes-related phenotypes, and in the genetic aetiology of population differences in these phenotypes... - Natural selection among Eurasians at genomic regions associated with HIV-1 controlYann C Klimentidis
Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
BMC Evol Biol 11:173. 2011.... - Prediction of expected years of life using whole-genome markersGustavo de Los Campos
Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
PLoS ONE 7:e40964. 2012.... - A comprehensive genetic approach for improving prediction of skin cancer risk in humansAna I Vazquez
Section on Statistical Genetics, Department of Biostatistics, University of Alabama, Birmingham, AL 35294, USA
Genetics 192:1493-502. 2012..We discuss avenues for improving prediction accuracy and speculate on the possible use of WGP to prospectively identify individuals at high risk... - Associations of obesity genes with obesity-related outcomes in multiethnic childrenYann C Klimentidis
Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, 1530 Third Avenue South, Birmingham, AL 35294 3360, USA
Arch Med Res 42:509-14. 2011.... - Beyond missing heritability: prediction of complex traitsRobert Makowsky
Department of Biostatistics, University of Alabama at Birmingham, Alabama, United States of America
PLoS Genet 7:e1002051. 2011..While such R(2) values vastly exceed what has been previously reported using a reduced number of pre-selected markers (<0.10), given the heritability of the trait (∼ 0.80), substantial room for improvement remains... - Canaries in the coal mine: a cross-species analysis of the plurality of obesity epidemicsYann C Klimentidis
Department of Biostatistics, University of Alabama, Birmingham, AL, USA
Proc Biol Sci 278:1626-32. 2011..g. viral pathogens, epigenetic factors). This finding may eventually enhance the discovery and fuller elucidation of other factors that have contributed to the recent rise in obesity rates... - A conserved role for syndecan family members in the regulation of whole-body energy metabolismMaria De Luca
Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
PLoS ONE 5:e11286. 2010..035) and intra-abdominal fat (P = 0.049), and SNP rs2267871 with insulin sensitivity (P = 0.037). Collectively, our results in Drosophila and humans argue that syndecan family members play a key role in the regulation of body metabolism...