Natalia M Kleinhans

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Atypical [corrected] participation of visual cortex during word processing in autism: an fMRI study of semantic decision
    Michael S Gaffrey
    Brain Development Imaging Laboratory, Department of Psychology, San Diego State University, San Diego, CA 92120, USA
    Neuropsychologia 45:1672-84. 2007
  2. ncbi request reprint Increased amygdala activation to neutral faces is associated with better face memory performance
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Seattle, Washington 98195, USA
    Neuroreport 18:987-91. 2007
  3. pmc N-acetyl aspartate in autism spectrum disorders: regional effects and relationship to fMRI activation
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Box 357115, Seattle, WA 98195, USA
    Brain Res 1162:85-97. 2007
  4. pmc Atypical functional lateralization of language in autism spectrum disorders
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Brain Res 1221:115-25. 2008
  5. doi request reprint Altered Dynamics of the fMRI Response to Faces in Individuals with Autism
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Box 357115, Seattle, WA, 98195, USA
    J Autism Dev Disord 46:232-41. 2016
  6. pmc Age-related abnormalities in white matter microstructure in autism spectrum disorders
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Seattle, WA, USA
    Brain Res 1479:1-16. 2012
  7. pmc Association between amygdala response to emotional faces and social anxiety in autism spectrum disorders
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Neuropsychologia 48:3665-70. 2010
  8. pmc fMRI evidence of neural abnormalities in the subcortical face processing system in ASD
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Neuroimage 54:697-704. 2011
  9. pmc Brief report: biochemical correlates of clinical impairment in high functioning autism and Asperger's disorder
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Box 357115, Seattle, WA 98195, USA
    J Autism Dev Disord 39:1079-86. 2009
  10. doi request reprint Reduced neural habituation in the amygdala and social impairments in autism spectrum disorders
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Box 357115, Seattle, WA 98195, USA
    Am J Psychiatry 166:467-75. 2009

Collaborators

Detail Information

Publications16

  1. pmc Atypical [corrected] participation of visual cortex during word processing in autism: an fMRI study of semantic decision
    Michael S Gaffrey
    Brain Development Imaging Laboratory, Department of Psychology, San Diego State University, San Diego, CA 92120, USA
    Neuropsychologia 45:1672-84. 2007
    ....
  2. ncbi request reprint Increased amygdala activation to neutral faces is associated with better face memory performance
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Seattle, Washington 98195, USA
    Neuroreport 18:987-91. 2007
    ..These findings indicate that the role of the amygdala may include processing neutral yet socially relevant stimuli. Further, amygdala activation, independent of emotional valence, appears to be associated with memory enhancement...
  3. pmc N-acetyl aspartate in autism spectrum disorders: regional effects and relationship to fMRI activation
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Box 357115, Seattle, WA 98195, USA
    Brain Res 1162:85-97. 2007
    ..Furthermore, this study provided the first direct evidence of the relationship between abnormal functional activation in prefrontal cortex and neuronal dysfunction in ASD...
  4. pmc Atypical functional lateralization of language in autism spectrum disorders
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Brain Res 1221:115-25. 2008
    ..Abnormal functional organization may contribute to the language impairment seen in ASD...
  5. doi request reprint Altered Dynamics of the fMRI Response to Faces in Individuals with Autism
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Box 357115, Seattle, WA, 98195, USA
    J Autism Dev Disord 46:232-41. 2016
    ..TD; area under the curve (AUC) = .852, p < .001]. In contrast, habituation to houses had no predictive value (AUC = .573, p = .365). Amygdala habituation to emotional faces may be useful for quantifying risk in ASD. ..
  6. pmc Age-related abnormalities in white matter microstructure in autism spectrum disorders
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Seattle, WA, USA
    Brain Res 1479:1-16. 2012
    ..Future longitudinal studies that include a wider range of ages and more extensive clinical characterization will be critical for further uncovering the neurodevelopmental processes unfolding during this dynamic time in development...
  7. pmc Association between amygdala response to emotional faces and social anxiety in autism spectrum disorders
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Neuropsychologia 48:3665-70. 2010
    ..These results indicate that level of social anxiety mediates the neural response to emotional face perception in ASD...
  8. pmc fMRI evidence of neural abnormalities in the subcortical face processing system in ASD
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Neuroimage 54:697-704. 2011
    ..Neural abnormalities in this system may contribute to early-emerging deficits in social orienting and attention, the putative precursors to abnormalities in social cognition and cortical face processing specialization...
  9. pmc Brief report: biochemical correlates of clinical impairment in high functioning autism and Asperger's disorder
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Box 357115, Seattle, WA 98195, USA
    J Autism Dev Disord 39:1079-86. 2009
    ..This suggests that altered metabolite levels in the amygdala may be associated with a more severe early developmental course in ASD...
  10. doi request reprint Reduced neural habituation in the amygdala and social impairments in autism spectrum disorders
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Box 357115, Seattle, WA 98195, USA
    Am J Psychiatry 166:467-75. 2009
    ..This study was designed to investigate whether abnormal habituation characterizes amygdala dysfunction in autism spectrum disorders and whether the rate of amygdala habituation is related to social impairment...
  11. doi request reprint Abnormal functional connectivity in autism spectrum disorders during face processing
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Box 357115, Seattle, WA 98195, USA
    Brain 131:1000-12. 2008
    ..These results suggest that abnormal neural connections within the limbic system may contribute to the social impairments observed in ASD...
  12. pmc An investigation of the relationship between fMRI and ERP source localized measurements of brain activity during face processing
    Neva M Corrigan
    Department of Radiology, University of Washington, 1100 NE 45th Street, Suite 555, Seattle, WA, 98195, USA
    Brain Topogr 22:83-96. 2009
    ..The combination of data from these techniques suggested that electrical brain activity at the latency of the N170 is highly represented in fMRI statistical maps...
  13. doi request reprint Functional neuroimaging in craniopharyngioma: a useful tool to better understand hypothalamic obesity?
    Christian L Roth
    Seattle Children s Research Institute, Center of Integrative Brain Research, University of Washington, Seattle, WA, USA
    Obes Facts 5:243-53. 2012
    ....
  14. doi request reprint Alterations in Connectivity on Functional Magnetic Resonance Imaging with Provocation of Lower Urinary Tract Symptoms: A MAPP Research Network Feasibility Study of Urological Chronic Pelvic Pain Syndromes
    Natalia M Kleinhans
    Department of Radiology, University of Washington, Seattle, Washington Department of Integrative Brain Imaging Center, University of Washington, Seattle, Washington
    J Urol 195:639-45. 2016
    ..We tested to see whether it could discriminate between persons with urological chronic pelvic pain syndrome-like symptoms and asymptomatic controls...
  15. pmc Acquired differences in brain responses among monozygotic twins discordant for restrained eating
    Ellen A Schur
    Division of General Internal Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, WA, United States
    Physiol Behav 105:560-7. 2012
    ..Because of the discordant monozygotic twin study design, the findings provide a rigorous level of support for the hypothesis that adopting an intention to restrain eating alters brain response to food cues...
  16. doi request reprint Posterior Cingulate Lactate as a Metabolic Biomarker in Amnestic Mild Cognitive Impairment
    Kurt E Weaver
    Department of Radiology, University of Washington, P O Box 357115, Seattle, WA 98195, USA Integrated Brain Imaging Center, University of Washington, Seattle, WA 98195, USA
    Biomed Res Int 2015:610605. 2015
    ....