Marlise I Klein

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Streptococcus mutans protein synthesis during mixed-species biofilm development by high-throughput quantitative proteomics
    Marlise I Klein
    Center for Oral Biology, University of Rochester Medical Center, Rochester, New York, USA
    PLoS ONE 7:e45795. 2012
  2. pmc Molecular approaches for viable bacterial population and transcriptional analyses in a rodent model of dental caries
    M I Klein
    Eastman Department of Dentistry and Center for Oral Biology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Mol Oral Microbiol 27:350-61. 2012
  3. pmc Novel antibiofilm chemotherapy targets exopolysaccharide synthesis and stress tolerance in Streptococcus mutans to modulate virulence expression in vivo
    Megan L Falsetta
    Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA
    Antimicrob Agents Chemother 56:6201-11. 2012
  4. pmc The exopolysaccharide matrix modulates the interaction between 3D architecture and virulence of a mixed-species oral biofilm
    Jin Xiao
    Center for Oral Biology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS Pathog 8:e1002623. 2012
  5. pmc Dynamics of Streptococcus mutans transcriptome in response to starch and sucrose during biofilm development
    Marlise I Klein
    Center for Oral Biology and Eastman Department of Dentistry, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 5:e13478. 2010
  6. pmc Influences of naturally occurring agents in combination with fluoride on gene expression and structural organization of Streptococcus mutans in biofilms
    Jae Gyu Jeon
    Center for Oral Biology, University of Rochester Medical Center, Rochester, New York, USA
    BMC Microbiol 9:228. 2009
  7. pmc Elevated incidence of dental caries in a mouse model of cystic fibrosis
    Marcelo A Catalán
    Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 6:e16549. 2011
  8. pmc The specific degree-of-polymerization of A-type proanthocyanidin oligomers impacts Streptococcus mutans glucan-mediated adhesion and transcriptome responses within biofilms
    Guoping Feng
    Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA
    Biofouling 29:629-40. 2013

Collaborators

  • Hyun Koo
  • JOSE A LEMOS
  • Gary Xie
  • William H Bowen
  • Jae Gyu Jeon
  • Megan L Falsetta
  • Guoping Feng
  • Jin Xiao
  • Marcelo A Catalán
  • Nicholi Vorsa
  • Stacy Gregoire
  • Ajay P Singh
  • John R Yates
  • Bingwen Lu
  • Senyo Agidi
  • Claire M Delahunty
  • Bruno B Silva
  • Kathy K Scott-Anne
  • Arne Heydorn
  • Kathleen Scott-Anne
  • James E Melvin

Detail Information

Publications8

  1. pmc Streptococcus mutans protein synthesis during mixed-species biofilm development by high-throughput quantitative proteomics
    Marlise I Klein
    Center for Oral Biology, University of Rochester Medical Center, Rochester, New York, USA
    PLoS ONE 7:e45795. 2012
    ..This reflects the intricate physiological processes linked to expression of virulence by this bacterium within complex biofilms...
  2. pmc Molecular approaches for viable bacterial population and transcriptional analyses in a rodent model of dental caries
    M I Klein
    Eastman Department of Dentistry and Center for Oral Biology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Mol Oral Microbiol 27:350-61. 2012
    ..Our approach could enhance the value of the current rodent model in further understanding the pathophysiology of this disease and facilitating the exploration of novel anti-caries therapies...
  3. pmc Novel antibiofilm chemotherapy targets exopolysaccharide synthesis and stress tolerance in Streptococcus mutans to modulate virulence expression in vivo
    Megan L Falsetta
    Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA
    Antimicrob Agents Chemother 56:6201-11. 2012
    ..These observations may have relevance for development of enhanced therapies against other biofilm-dependent infections...
  4. pmc The exopolysaccharide matrix modulates the interaction between 3D architecture and virulence of a mixed-species oral biofilm
    Jin Xiao
    Center for Oral Biology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS Pathog 8:e1002623. 2012
    ..These observations may have relevance beyond the mouth, as matrix is inherent to all biofilms...
  5. pmc Dynamics of Streptococcus mutans transcriptome in response to starch and sucrose during biofilm development
    Marlise I Klein
    Center for Oral Biology and Eastman Department of Dentistry, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 5:e13478. 2010
    ..Our data show complex remodeling of S. mutans-transcriptome in response to changing environmental conditions in situ, which could modulate the dynamics of biofilm development and pathogenicity...
  6. pmc Influences of naturally occurring agents in combination with fluoride on gene expression and structural organization of Streptococcus mutans in biofilms
    Jae Gyu Jeon
    Center for Oral Biology, University of Rochester Medical Center, Rochester, New York, USA
    BMC Microbiol 9:228. 2009
    ..mutans within biofilms and their structural organization using real-time PCR and confocal fluorescence microscopy...
  7. pmc Elevated incidence of dental caries in a mouse model of cystic fibrosis
    Marcelo A Catalán
    Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 6:e16549. 2011
    ..Given the close relationship between pH and caries development, we hypothesized that caries incidence might be elevated in the mouse CF model...
  8. pmc The specific degree-of-polymerization of A-type proanthocyanidin oligomers impacts Streptococcus mutans glucan-mediated adhesion and transcriptome responses within biofilms
    Guoping Feng
    Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA
    Biofouling 29:629-40. 2013
    ..This study identified putative molecular targets of A-type cranberry PACs in S. mutans while demonstrating that PAC oligomers with a specific DP may be effective in disrupting the assembly of cariogenic biofilms. ..