Research Topics
| Wendy Klein-SchwartzSummaryAffiliation: University of Maryland Country: USA Publications
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Detail Information
Publications
Comparison of citalopram and other selective serotonin reuptake inhibitor ingestions in childrenWendy Klein-Schwartz
Maryland Poison Center, University of Maryland School of Pharmacy, 220 Arch Street, Baltimore, MD 21201, USA
Clin Toxicol (Phila) 50:418-23. 2012..Data in children are lacking, yet the 2007 American Association of Poison Control Centers out-of-hospital citalopram consensus guideline mirrors the guideline for other SSRIs...
Toxicity of polysaccharide--iron complex exposures reported to poison control centersW Klein-Schwartz
Research and Education, Maryland Poison Center, Baltimore 21201, USA
Ann Pharmacother 34:165-9. 2000..To evaluate the toxicity of polysaccharide-iron complex (PIC) exposures reported to poison centers in the US...- Impact of the voluntary withdrawal of over-the-counter cough and cold medications on pediatric ingestions reported to poison centersWendy Klein-Schwartz
Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, MD, USA
Pharmacoepidemiol Drug Saf 19:819-24. 2010..To assess the impact of a voluntary withdrawal of over-the-counter cough and cold medications (OTC CCMs) labeled for children under age 2 years on pediatric ingestions reported to the American Association of Poison Control Centers... - Prospective observational multi-poison center study of ziprasidone exposuresWendy Klein-Schwartz
Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, Maryland 21201, USA
Clin Toxicol (Phila) 45:782-6. 2007..We characterized the clinical manifestations associated with ziprasidone overdoses, in particular the incidence and severity of QTc prolongation... - Characterization of gabapentin overdose using a poison center case seriesWendy Klein-Schwartz
Maryland Poison Center, Department of Pharmacy Practice and Science, University of Maryland School of Pharmacy, Baltimore, Maryland 21201, USA
J Toxicol Clin Toxicol 41:11-5. 2003..Gabapentin is an anticonvulsant that is being used for an increasing number of off-label indications. The purpose of this study is to document the clinical manifestations and outcomes of gabapentin exposures reported to poison centers... - Poison centers' experience with methylphenidate abuse in pre-teens and adolescentsWendy Klein-Schwartz
Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA
J Am Acad Child Adolesc Psychiatry 42:288-94. 2003..To evaluate trends and toxicity of methylphenidate abuse in pre-teens and adolescents reported to poison centers... - Intravenous acetylcysteine for the treatment of acetaminophen overdoseWendy Klein-Schwartz
University of Maryland, School of Pharmacy, 220 Arch Street, Room 01 108, Baltimore, MD 21201, USA
Expert Opin Pharmacother 12:119-30. 2011.... - Abuse and toxicity of methylphenidateWendy Klein-Schwartz
Research and Education, Maryland Poison Center and Department of Pharmacy Practice and Science, University of Maryland School of Pharmacy, Baltimore, Maryland 21201, USA
Curr Opin Pediatr 14:219-23. 2002..Despite its abuse potential, there is disagreement regarding the extent to which methylphenidate is being diverted from legitimate use to abuse in preteens and adolescents... - Trends and toxic effects from pediatric clonidine exposuresWendy Klein-Schwartz
Maryland Poison Center, Department of Pharmacy Practice and Science, University of Maryland School of Pharmacy, 20 N Pine St, Baltimore, MD 21201, USA
Arch Pediatr Adolesc Med 156:392-6. 2002..To analyze the trends, demographics, and toxic effects associated with pediatric clonidine hydrochloride exposures reported to poison centers... - Frequency of medication errors with intravenous acetylcysteine for acetaminophen overdoseBryan D Hayes
Maryland Poison Center, School of Pharmacy, University of Maryland, Baltimore, MD, USA
Ann Pharmacother 42:766-70. 2008..The dosing regimen is complex, consisting of a loading dose followed by 2 maintenance doses, each with different infusion rates... - Unexpected late rise in plasma acetaminophen concentrations with change in risk stratification in acute acetaminophen overdosesPatrick P Dougherty
Clinical Toxicology, University of Maryland School of Pharmacy, Maryland Poison Center, Baltimore, Maryland, USA
J Emerg Med 43:58-63. 2012..There are case reports of patients with acute overdoses of acetaminophen combination products in whom a toxic PAC occurred later after an initial non-toxic PAC at approximately 4 h... - Hepatotoxicity despite early administration of intravenous N-acetylcysteine for acute acetaminophen overdoseSuzanne Doyon
Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, MD, USA
Acad Emerg Med 16:34-9. 2009..The objective was to evaluate the effectiveness of intravenous N-acetylcysteine (IV NAC; 300 mg/kg over 21 hours) in early acute acetaminophen (APAP) overdose patients... - Comparison of toxicity of acute overdoses with citalopram and escitalopramBryan D Hayes
Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, Maryland 21230, USA
J Emerg Med 39:44-8. 2010..Seizures and QTc prolongation are associated with citalopram poisoning; however, overdose experience with escitalopram is more limited... - Incidence and onset of delayed seizures after overdoses of extended-release bupropionPaul Starr
Maryland Poison Center Department of Pharmacy Practice and Science, University of Maryland Baltimore, Baltimore, MD 21201, USA
Am J Emerg Med 27:911-5. 2009..This study systematically evaluates the frequency and timing of seizures and an association between other toxic effects (ie, agitation, tremors, and hallucinations) and seizures... - Atypical experience: a case series of pediatric aripiprazole exposuresAmanda L Lofton
Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, MD 21201-1180, USA
Clin Toxicol (Phila) 43:151-3. 2005..Adolescents in this series experienced only minor, if any, clinical effects. Major clinical effects, i.e., seizures, dysrhythmias, were not reported in this series... - Toxicity of buprenorphine overdoses in childrenBryan D Hayes
PharmD, Maryland Poison Center, University of Maryland School of Pharmacy, 220 Arch St, Office Level 1, Baltimore, MD 21201, USA
Pediatrics 121:e782-6. 2008..The purpose of this study was to analyze buprenorphine overdoses in young children reported by US poison centers to the Researched Abuse, Diversion, and Addiction-Related Surveillance System... - Evaluation of lamotrigine toxicity reported to poison centersAmanda L Lofton
Maryland Poison Center, School of Pharmacy, University of Maryland, Baltimore, MD, USA
Ann Pharmacother 38:1811-5. 2004..6%) cases. There were no deaths. CONCLUSIONS: These data demonstrate that the majority of patients exposed to lamotrigine in overdose experienced minor or no clinical effects. Although rare, serious effects can also occur... - Epidemiology and toxicity of pediatric guanfacine exposuresJean C McGrath
Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, MD, USA
Ann Pharmacother 36:1698-703. 2002..To examine the epidemiology and toxicity of guanfacine exposures in children and adolescents reported to poison control centers... - Octreotide's role in the management of sulfonylurea-induced hypoglycemiaPatrick P Dougherty
Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA
J Med Toxicol 6:199-206. 2010..Based on animal and human data, there is sufficient evidence to recommend the use of octreotide with supplemental dextrose for the treatment of sulfonylurea-induced hypoglycemia... - Consistency between coded poison center data and fatality abstract narratives for therapeutic error deaths in older adultsBryan D Hayes
Department of Pharmacy Services, University of Maryland Medical Center, Baltimore, MD, USA
Clin Toxicol (Phila) 48:68-71. 2010..A secondary goal was to elucidate causes and coding consistency for fatal iatrogenic errors... - Causes of therapeutic errors in older adults: evaluation of National Poison Center dataBryan D Hayes
Maryland Poison Center, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201, USA
J Am Geriatr Soc 57:653-8. 2009..To evaluate the reasons for unintentional therapeutic errors in older adults, the types of medications most frequently involved, and the medical outcomes related to these adverse drug events... - Potential for erroneous interpretation of poisoning outcomes due to changes in National Poison Data System reportingBruce Anderson
Maryland Poison Center, University of Maryland School of Pharmacy, 220 Arch St, Baltimore, MD 21201, USA
Clin Toxicol (Phila) 48:745-9. 2010..The objective of this study is to describe the potential impact of this reporting change on longitudinal analysis of outcomes... - Pediatric methylphenidate exposures: 7-year experience of poison centers in the United StatesWendy Klein-Schwartz
Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA
Clin Pediatr (Phila) 42:159-64. 2003..The trend of increasing frequency of methylphenidate exposures reported to poison centers exactly parallels increasing therapeutic use... - Acute, unintentional pediatric brodifacoum ingestionsGreene Shepherd
Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, USA
Pediatr Emerg Care 18:174-8. 2002..Large overdoses and chronic intoxication have been associated with significant coagulopathies and death. Currently, the management of acute unintentional ingestions by young children is controversial... - A novel approach to informing the public about the risks of overdose and nonmedical use of prescription medicationsSuzanne Doyon
School of Pharmacy, University of Maryland, Baltimore, MD, USA
Am J Addict 22:108-12. 2013..Implementation of a telephone-based program of overdose prevention and screening for nonmedical use of prescription medications is examined... 
Decrease in therapeutic errors involving prescription cough and cold medications in young childrenSuzanne Doyon
University of Maryland School of Pharmacy, Maryland Poison Center, Baltimore, Maryland
J Pediatr Pharmacol Ther 17:84-7. 2012....- Polypharmacy and the geriatric patientBryan D Hayes
Maryland Poison Center, University of Maryland, School of Pharmacy, 220 Arch Street, Baltimore, MD 21201, USA
Clin Geriatr Med 23:371-90, vii. 2007..Application of Beers criteria, appropriate therapeutic drug monitoring, and careful, periodic review of the patient's medication list will assist with preventing the sometimes lethal complications of polypharmacy... - Drug adsorption efficacy and palatability of a novel charcoal cookie formulationWendy Klein-Schwartz
Maryland Poison Center, Baltimore, Maryland 21201, USA
Pharmacotherapy 30:888-94. 2010..To determine the effect of a novel charcoal cookie formulation compared with a standard aqueous charcoal product on the absorption of orally administered cimetidine, and to compare the palatability of the two charcoal products... - Reply to clonidine exposures, not toxicityHenry A Spiller
J Pediatr 149:282-3. 2006 - 2001 Annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance SystemToby L Litovitz
Am J Emerg Med 20:391-452. 2002 - Toxic clonidine ingestion in childrenHenry A Spiller
Kentucky Regional Poison Center, Louisville, Kentucky 40232-5070, USA
J Pediatr 146:263-6. 2005..1 mg, (2) ingestion of >0.2 mg in children 5 to 8 years of age, and (3) ingestion of >or=0.4 mg in children older than 8 years of age. Observation for 4 hours may be sufficient to detect patients who will develop severe effects... - 2003 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance SystemWilliam A Watson
Am J Emerg Med 22:335-404. 2004 - 2004 Annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance SystemWilliam A Watson
American Association of Poison Control Centers, 3201 New Mexico Avenue, Ste. 330, Washington, DC 20016, USA
Am J Emerg Med 23:589-666. 2005 - Evaluation of toxicity of topiramate exposures reported to poison centersA L Lofton
Beverly Hospital, Northeast Health Systems, USA
Hum Exp Toxicol 24:591-5. 2005..Serious toxic effects, such as CNS depression with respiratory depression or persistent non-anion gap metabolic acidosis, are infrequent... - 2005 Annual Report of the American Association of Poison Control Centers' national poisoning and exposure databaseMelisa W Lai
American Association of Poison Control Centers, Washington, DC, USA
Clin Toxicol (Phila) 44:803-932. 2006.... - Are 1-2 dangerous? Chloroquine and hydroxychloroquine exposure in toddlersE Reed Smith
Department of Emergency Medicine, George Washington University Medical Center, Washington, DC 20007, USA
J Emerg Med 28:437-43. 2005..Thus, similar recommendations should be followed for triage after accidental hydroxychloroquine overdose... - Efficacy of activated charcoal administered more than four hours after acetaminophen overdoseHenry A Spiller
Kentucky Regional Poison Center, Louisville, Kentucky 40232-5070, USA
J Emerg Med 30:1-5. 2006.... - Adverse events associated with dietary supplements: an observational studyMary E Palmer
Department of Emergency Medicine, Landspitali University Hospital, Fossvogi, 108, Reykjavik, Iceland
Lancet 361:101-6. 2003..Adverse events associated with dietary supplements are difficult to monitor in the USA, because such products are not registered before sale, and there is little information about their content and safety... - Electrocardiographic changes associated with beta-blocker toxicityJeffrey N Love
Emergency Department, Georgetown University, Washington, DC, USA
Ann Emerg Med 40:603-10. 2002..We sought to characterize the ECG changes associated with symptomatic beta-blocker overdose... - High-dose insulin therapy for calcium-channel blocker overdoseGreene Shepherd
College of Pharmacy, University of Georgia, Augusta, GA, USA
Ann Pharmacother 39:923-30. 2005..To evaluate the evidence for using high-dose insulin therapy with supplemental dextrose and potassium in calcium-channel blocker (CCB) overdose... - 2002 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance SystemWilliam A Watson
Am J Emerg Med 21:353-421. 2003