Scott Kitchen

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Stem-cell-based gene therapy for HIV infection
    Anjie Zhen
    Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, CA 90095, USA
    Viruses 6:1-12. 2014
  2. pmc In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells
    Scott G Kitchen
    Division of Hematology Oncology, The David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America
    PLoS Pathog 8:e1002649. 2012
  3. pmc Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice
    Scott G Kitchen
    Division of Hematology Oncology, The David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 4:e8208. 2009
  4. pmc CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes
    Marta Epeldegui
    Department of Microbiology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 5:e11448. 2010
  5. pmc Macrophage differentiation from embryoid bodies derived from human embryonic stem cells
    Aparna Subramanian
    Department of Medicine, Division of Hematology Oncology
    J Stem Cells 4:29-45. 2009

Research Grants

  1. The role of CD4 in macrophage differentiation and function
    Scott Kitchen; Fiscal Year: 2009
  2. The Role of CD8 on CD4+ T Cells
    Scott Kitchen; Fiscal Year: 2004
  3. The role of CD4 in macrophage differentiation and function
    Scott G Kitchen; Fiscal Year: 2010

Collaborators

Detail Information

Publications5

  1. pmc Stem-cell-based gene therapy for HIV infection
    Anjie Zhen
    Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, CA 90095, USA
    Viruses 6:1-12. 2014
    ..The first is to generate immune systems resistant to HIV infection while the second strategy involves enhancing anti-HIV immunity to eliminate HIV infected cells. ..
  2. pmc In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells
    Scott G Kitchen
    Division of Hematology Oncology, The David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America
    PLoS Pathog 8:e1002649. 2012
    ..These results strongly suggest that stem cell based gene therapy may be a feasible approach in the treatment of chronic viral infections and provide a foundation towards the development of this type of strategy...
  3. pmc Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice
    Scott G Kitchen
    Division of Hematology Oncology, The David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 4:e8208. 2009
    ....
  4. pmc CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes
    Marta Epeldegui
    Department of Microbiology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 5:e11448. 2010
    ..These findings are consistent with a role for HIV in the direct stimulation of B cells, potentially leading to the accumulation of molecular lesions that have the potential to contribute to the development of NHL...
  5. pmc Macrophage differentiation from embryoid bodies derived from human embryonic stem cells
    Aparna Subramanian
    Department of Medicine, Division of Hematology Oncology
    J Stem Cells 4:29-45. 2009
    ..Furthermore, this system is amenable to genetic manipulation and may thus be used to study important mechanisms of macrophage differentiation and function...

Research Grants3

  1. The role of CD4 in macrophage differentiation and function
    Scott Kitchen; Fiscal Year: 2009
    ....
  2. The Role of CD8 on CD4+ T Cells
    Scott Kitchen; Fiscal Year: 2004
    ..These studies combined will allow us to determine the possible effects that the appearance or loss of this subset may have on HIV disease progression and antiviral immunity. ..
  3. The role of CD4 in macrophage differentiation and function
    Scott G Kitchen; Fiscal Year: 2010
    ....