A E Kitabchi

Summary

Affiliation: University of Tennessee
Country: USA

Publications

  1. ncbi Evidence for strict inpatient blood glucose control: time to revise glycemic goals in hospitalized patients
    Abbas E Kitabchi
    University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Metabolism 57:116-20. 2008
  2. ncbi Changes in serum leptin in lean and obese subjects with acute hyperglycemic crises
    Abbas E Kitabchi
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Clin Endocrinol Metab 88:2593-6. 2003
  3. ncbi Diabetic ketoacidosis induces in vivo activation of human T-lymphocytes
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 315:404-7. 2004
  4. ncbi Thirty years of personal experience in hyperglycemic crises: diabetic ketoacidosis and hyperglycemic hyperosmolar state
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes, and Metabolism, University of Tennessee Health Science Center, 920 Madison Avenue 909, Memphis, TN 38163, USA
    J Clin Endocrinol Metab 93:1541-52. 2008
  5. ncbi Is a priming dose of insulin necessary in a low-dose insulin protocol for the treatment of diabetic ketoacidosis?
    Abbas E Kitabchi
    Department of Medicine and Molecular Sciences, Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Diabetes Care 31:2081-5. 2008
  6. ncbi Hyperglycemic crises in diabetes mellitus: diabetic ketoacidosis and hyperglycemic hyperosmolar state
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Endocrinol Metab Clin North Am 35:725-51, viii. 2006
  7. ncbi Management of type 2 diabetes. Evolving strategies for treatment
    G E Umpierrez
    Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Obstet Gynecol Clin North Am 28:401-19, viii. 2001
  8. ncbi Hyperglycemic crises in adult patients with diabetes: a consensus statement from the American Diabetes Association
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, 956 Court Ave, Suite D334, Memphis, Tennessee 38163, USA
    Diabetes Care 29:2739-48. 2006
  9. ncbi Hyperglycemia-induced activation of human T-lymphocytes with de novo emergence of insulin receptors and generation of reactive oxygen species
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 335:491-5. 2005
  10. ncbi De novo emergence of growth factor receptors in activated human CD4+ and CD8+ T lymphocytes
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Tennessee Health Science Center, Memphis 38163, USA
    Metabolism 53:117-22. 2004

Detail Information

Publications43

  1. ncbi Evidence for strict inpatient blood glucose control: time to revise glycemic goals in hospitalized patients
    Abbas E Kitabchi
    University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Metabolism 57:116-20. 2008
    ..We propose a more conservative approach of glycemic control than current American Association of Clinical Endocrinology recommendations until results of prospective, multicenter, randomized studies become available...
  2. ncbi Changes in serum leptin in lean and obese subjects with acute hyperglycemic crises
    Abbas E Kitabchi
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Clin Endocrinol Metab 88:2593-6. 2003
    ..The low serum leptin level on admission in subjects with hyperglycemic crises may be the result of impaired adipocyte glucose utilization due to insulin deficiency and/or to increased catecholamine levels...
  3. ncbi Diabetic ketoacidosis induces in vivo activation of human T-lymphocytes
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 315:404-7. 2004
    ..We propose DKA changes the T-lymphocytes to insulin sensitive tissues as a compensatory mechanism...
  4. ncbi Thirty years of personal experience in hyperglycemic crises: diabetic ketoacidosis and hyperglycemic hyperosmolar state
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes, and Metabolism, University of Tennessee Health Science Center, 920 Madison Avenue 909, Memphis, TN 38163, USA
    J Clin Endocrinol Metab 93:1541-52. 2008
    ..This paper summarizes the results of these prospective studies on the management and pathophysiology of DKA...
  5. ncbi Is a priming dose of insulin necessary in a low-dose insulin protocol for the treatment of diabetic ketoacidosis?
    Abbas E Kitabchi
    Department of Medicine and Molecular Sciences, Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Diabetes Care 31:2081-5. 2008
    ..The purpose of this study was to assess the efficacy of an insulin priming dose with a continuous insulin infusion versus two continuous infusions without a priming dose...
  6. ncbi Hyperglycemic crises in diabetes mellitus: diabetic ketoacidosis and hyperglycemic hyperosmolar state
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Endocrinol Metab Clin North Am 35:725-51, viii. 2006
    ..DKA and HHS also are economically burdensome; therefore, any resources invested in their prevention would be rewarding...
  7. ncbi Management of type 2 diabetes. Evolving strategies for treatment
    G E Umpierrez
    Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Obstet Gynecol Clin North Am 28:401-19, viii. 2001
    ..This article examines the current classification, diagnostic criteria for diabetes, and screening recommendations and provides a therapeutic strategy for improving glycemic control in patients with type 2 diabetes...
  8. ncbi Hyperglycemic crises in adult patients with diabetes: a consensus statement from the American Diabetes Association
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, 956 Court Ave, Suite D334, Memphis, Tennessee 38163, USA
    Diabetes Care 29:2739-48. 2006
  9. ncbi Hyperglycemia-induced activation of human T-lymphocytes with de novo emergence of insulin receptors and generation of reactive oxygen species
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 335:491-5. 2005
    ..We propose that activation of T-cells with development of insulin receptors in hyperglycemic conditions may serve as a mechanism for control of glucose entry into these cells, thus, protecting them against glucose toxicity...
  10. ncbi De novo emergence of growth factor receptors in activated human CD4+ and CD8+ T lymphocytes
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Tennessee Health Science Center, Memphis 38163, USA
    Metabolism 53:117-22. 2004
    ....
  11. ncbi Active use of cocaine: an independent risk factor for recurrent diabetic ketoacidosis in a city hospital
    Ebenezer A Nyenwe
    Department of Medicine, Bronx Lebanon Hospital Center, Albert Einstein College of Medicine, Bronx, New York, USA
    Endocr Pract 13:22-9. 2007
    ..To identify the risk factors for recurrent diabetic ketoacidosis (DKA) in a city hospital...
  12. ncbi Palmitic acid-induced activation of human T-lymphocytes and aortic endothelial cells with production of insulin receptors, reactive oxygen species, cytokines, and lipid peroxidation
    Frankie B Stentz
    Division of Endocrinology Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 346:721-6. 2006
    ..We hypothesize that these events may serve as protective defense mechanisms against acute effects of glucotoxicity and lipotoxicity in these cells...
  13. ncbi Effects of intravenous glucose load on insulin secretion in patients with ketosis-prone diabetes during near-normoglycemia remission
    Aidar R Gosmanov
    Department of Medicine, Emory University, Atlanta, Georgia, USA
    Diabetes Care 33:854-60. 2010
    ..The aim of this study was to determine the effect of glucotoxicity on beta-cell function during remission in obese patients with KPD...
  14. ncbi Immunogenetic analysis suggests different pathogenesis for obese and lean African-Americans with diabetic ketoacidosis
    G E Umpierrez
    Department of Medicine, Emory University, Atlanta, Georgia 30312, USA
    Diabetes Care 22:1517-23. 1999
    ..The aim of this study was to determine whether obese African-American patients with DKA could be determined to have type 1 or type 2 diabetes based on insulin secretion or the presence of immunological and genetic markers...
  15. ncbi Does syndrome X exist in hypertensive elderly persons with impaired glycemic control?
    K C Johnson
    Department of Preventive Medicine, University of Tennessee, Memphis 38163, USA
    J Gerontol A Biol Sci Med Sci 54:M571-6. 1999
    ..This report focuses on the glycemic state in relation to insulin and lipid levels of a cohort of elderly hypertensive persons to estimate the prevalence of syndrome X...
  16. ncbi Transcriptome and proteome expressions involved in insulin resistance in muscle and activated T-lymphocytes of patients with type 2 diabetes
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Genomics Proteomics Bioinformatics 5:216-35. 2007
    ..These alterations in transcriptomes and proteomes in T2DM may be involved in insulin resistance...
  17. ncbi Laparoscopic bariatric patients' will to help: the foundation of research
    David S Tichansky
    Section of Minimally Invasive Surgery, Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Surg Obes Relat Dis 3:180-3. 2007
    ..Bariatric patient enthusiasm for research participation has never been objectively measured. Our hypothesis was that most laparoscopic bariatric surgery patients would participate in clinical research...
  18. ncbi Intravenous intralipid-induced blood pressure elevation and endothelial dysfunction in obese African-Americans with type 2 diabetes
    Guillermo E Umpierrez
    Department of Medicine, General Clinical Research Center, Emory University School of Medicine, 49 Jesse Hill Jr Drive, Atlanta, Georgia 30303, USA
    J Clin Endocrinol Metab 94:609-14. 2009
    ..We evaluated the effect of sustained elevations of FFA on blood pressure, endothelial function, insulin secretion, inflammatory markers, and renin-angiotensin system...
  19. ncbi Lack of lipotoxicity effect on {beta}-cell dysfunction in ketosis-prone type 2 diabetes
    Guillermo E Umpierrez
    Department of Medicine, Emory University, Atlanta, Georgia, USA
    Diabetes Care 33:626-31. 2010
    ..A high FFA level by intralipid infusion for 48 h was not associated with beta-cell decompensation (lipotoxicity) in KPDM patients...
  20. ncbi Admission hyperglycemia and other risk factors as predictors of hospital mortality in a medical ICU population
    Amado X Freire
    Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, University of Tennessee Health Science Center, Memphis, 38163, USA
    Chest 128:3109-16. 2005
    ..Tight glycemic control is recommended for patients in the ICU, as hyperglycemia is associated with increased morbidity and mortality...
  21. ncbi Activated T lymphocytes in Type 2 diabetes: implications from in vitro studies
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Curr Drug Targets 4:493-503. 2003
    ..Due to the accessibility of obtaining these cells from patients, activated T-lymphocytes offer the potential of studying diabetes and other disease in human subjects...
  22. ncbi Thyroid dysfunction in patients with type 1 diabetes: a longitudinal study
    Guillermo E Umpierrez
    Division of Endocrinology, Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Diabetes Care 26:1181-5. 2003
    ..However, longitudinal studies to determine the natural history of thyroid dysfunction in patients with type 1 diabetes are lacking...
  23. ncbi Predictors of intensive care unit and hospital length of stay in diabetic ketoacidosis
    Amado X Freire
    Department of Medicine, The University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
    J Crit Care 17:207-11. 2002
    ....
  24. ncbi Hyperglycemia: an independent marker of in-hospital mortality in patients with undiagnosed diabetes
    Guillermo E Umpierrez
    Division of Endocrinology and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Clin Endocrinol Metab 87:978-82. 2002
    ..Patients with newly diagnosed hyperglycemia had a significantly higher mortality rate and a lower functional outcome than patients with a known history of diabetes or normoglycemia...
  25. ncbi Proinflammatory cytokines, markers of cardiovascular risks, oxidative stress, and lipid peroxidation in patients with hyperglycemic crises
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Diabetes 53:2079-86. 2004
    ..Return of these values to normal levels with insulin therapy demonstrates a robust anti-inflammatory effect of insulin...
  26. ncbi Transcriptome and proteome expression in activated human CD4 and CD8 T-lymphocytes
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN, USA
    Biochem Biophys Res Commun 324:692-6. 2004
    ..To our knowledge this is the first report of an hitherto unreported event. Possible implications of these processes are discussed in the light of their physiological significance...
  27. ncbi Diabetic ketoacidosis: risk factors and management strategies
    Guillermo E Umpierrez
    Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Treat Endocrinol 2:95-108. 2003
    ..Novel approaches to patient education incorporating a variety of healthcare beliefs and socioeconomic issues are critical to an effective prevention program...
  28. ncbi Treatment of diabetic ketoacidosis with subcutaneous insulin aspart
    Guillermo E Umpierrez
    Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30303, USA
    Diabetes Care 27:1873-8. 2004
    ....
  29. ncbi Risk of new-onset diabetes mellitus and worsening glycaemic variables for established diabetes in men undergoing androgen-deprivation therapy for prostate cancer
    Ithaar H Derweesh
    Department of Urology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    BJU Int 100:1060-5. 2007
    ....
  30. ncbi Racial differences in the correlation between gonadal androgens and serum insulin levels
    A E Kitabchi
    Department of Medicine, The Clinical Research Center, University of Tennessee, Memphis 38163, USA
    Diabetes Care 22:1524-9. 1999
    ..To examine these potentially important racial differences further, 14 premenopausal females from each ethnic group, of similar age, BMI, and waist-to-hip ratio, were studied...
  31. ncbi Proinflammatory cytokines in response to insulin-induced hypoglycemic stress in healthy subjects
    Laleh Razavi Nematollahi
    The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Metabolism 58:443-8. 2009
    ..Elevations of NE, EP, corticotropin, and cortisol in hypoglycaemia are associated with the elevation of the proinflammatory cytokines and leukocytosis...
  32. ncbi De novo emergence of insulin-stimulated glucose uptake in human aortic endothelial cells incubated with high glucose
    Aidar R Gosmanov
    Department of Medicine, The University of Tennessee Health Science Center, 956 Court Ave, Suite D334, Memphis, TN 38163, USA
    Am J Physiol Endocrinol Metab 290:E516-22. 2006
    ....
  33. ncbi Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program
    Allan F Moore
    Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
    Diabetes 57:2503-10. 2008
    ....
  34. ncbi Hyperglycemic crises in patients with diabetes mellitus
    Abbas E Kitabchi
    Diabetes Care 26:S109-17. 2003
  35. ncbi The use of alkali therapy in severe diabetic ketoacidosis
    Kashif A Latif
    Diabetes Care 25:2113-4. 2002
  36. ncbi Ketosis-prone diabetes--a new subgroup of patients with atypical type 1 and type 2 diabetes?
    Abbas E Kitabchi
    J Clin Endocrinol Metab 88:5087-9. 2003
  37. ncbi Sliding-scale insulin: more evidence needed before final exit?
    Abbas E Kitabchi
    Diabetes Care 30:2409-10. 2007
  38. ncbi Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial
    Xavier Pi-Sunyer
    St Luke s Roosevelt Hospital Center, USA
    Diabetes Care 30:1374-83. 2007
    ..This report describes 1-year changes in CVD risk factors in a trial designed to examine the long-term effects of an intensive lifestyle intervention on the incidence of major CVD events...
  39. ncbi Hyperglycemic crises in diabetes
    Abbas E Kitabchi
    Diabetes Care 27:S94-102. 2004
  40. ncbi Narrative review: ketosis-prone type 2 diabetes mellitus
    Guillermo E Umpierrez
    Emory University School of Medicine, Atlanta, Georgia 30303, USA
    Ann Intern Med 144:350-7. 2006
    ..The underlying mechanisms for beta-cell dysfunction in ketosis-prone type 2 diabetes are not known; however, preliminary evidence suggests an increased susceptibility to glucose desensitization...
  41. ncbi Hyperglycemic crises: improving prevention and management
    Abbas E Kitabchi
    Am Fam Physician 71:1659-60. 2005
  42. ncbi Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin
    Abbas E Kitabchi
    Diabetes Prevention Program Coordinating Center, The Biostatistics Center, George Washington University, Rockville, MD 20852, USA
    Diabetes 54:2404-14. 2005
    ..The better preventive effectiveness of intensive lifestyle may be due to improved insulin sensitivity concomitant with preservation of beta-cell function...
  43. ncbi Pathogenic potential of adipose tissue and metabolic consequences of adipocyte hypertrophy and increased visceral adiposity
    Harold E Bays
    L MARC Research Center, 3288 Illinois Avenue, Louisville, KY 40213, USA
    Expert Rev Cardiovasc Ther 6:343-68. 2008
    ....