Research Topics
| Jessica KissingerSummaryAffiliation: University of Georgia Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Identification and functional characterization of cis-regulatory elements in the apicomplexan parasite Toxoplasma gondiiNandita Mullapudi
Department of Genetics, University of Georgia, East Green Street, Athens, Georgia 30602, USA
Genome Biol 10:R34. 2009..We have approached the question of gene regulation from a sequence perspective by mining the genomic sequence data to identify putative cis-regulatory elements using a de novo approach...- Phylogenomic evidence supports past endosymbiosis, intracellular and horizontal gene transfer in Cryptosporidium parvumJinling Huang
Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA
Genome Biol 5:R88. 2004..Given the importance of gene transfers in eukaryotic evolution and the potential implications for chemotherapy, it is important to identify the complement of transferred genes in Cryptosporidium... - piggyBac is an effective tool for functional analysis of the Plasmodium falciparum genomeBharath Balu
Department of Global Health, University of South Florida, Tampa, Florida 33612, USA
BMC Microbiol 9:83. 2009..Transposon mutagenesis has been used widely to identify gene functions in many organisms and would be extremely valuable for functional analysis of the Plasmodium genome... - Identification of putative cis-regulatory elements in Cryptosporidium parvum by de novo pattern findingNandita Mullapudi
Department of Genetics and Center for Tropical and Emerging Global Diseases, Paul D Coverdell Center, University of Georgia, Athens, GA 30602, USA
BMC Genomics 8:13. 2007..parvum. To support our findings, we have established comparative real-time -PCR expression profiles for the groups of genes examined computationally... - The Alveolate Perkinsus marinus: biological insights from EST gene discoverySandeep J Joseph
Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA
BMC Genomics 11:228. 2010..g. parasitism) within the Alveolata. Despite intense parasite pressure, no disease-resistant oysters have been identified and no effective therapies have been developed to date... - Consistent and contrasting properties of lineage-specific genes in the apicomplexan parasites Plasmodium and TheileriaChih Horng Kuo
Department of Genetics, University of Georgia, Athens, GA 30602, USA
BMC Evol Biol 8:108. 2008..In parasitic organisms, lineage-specific gene products are possible targets for vaccine development or therapeutics when these genes are absent from the host genome... - Genome cartography: charting the apicomplexan genomeJessica C Kissinger
Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, USA
Trends Parasitol 27:345-54. 2011.... 
SynView: a GBrowse-compatible approach to visualizing comparative genome dataHaiming Wang
Center for Tropical and Emerging Global Diseases, University of Georgia Athens, GA 30602-2606, USA
Bioinformatics 22:2308-9. 2006..CryptoDB.org) projects and can be easily integrated into other cross-species comparative genome projects. AVAILABILITY: The program and instructions are freely available at http://www.ApiDB.org/apps/SynView/ CONTACT: ...- A tale of three genomes: the kinetoplastids have arrivedJessica C Kissinger
Department of Genetics and Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30606, USA
Trends Parasitol 22:240-3. 2006.... - A first glimpse into the pattern and scale of gene transfer in ApicomplexaJinling Huang
Center for Tropical and Emerging Global Diseases, University of Georgia, 623 Biological Sciences, Athens, GA 30602 2606, USA
Int J Parasitol 34:265-74. 2004.... 
Emergence of a group 3 coronavirus through recombinationMark W Jackwood
Department of Population Health, College of Veterinary Medicine, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
Virology 398:98-108. 2010....- CryptoDB: a Cryptosporidium bioinformatics resource updateMark Heiges
Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, USA
Nucleic Acids Res 34:D419-22. 2006.... - Many gene and domain families have convergent fates following independent whole-genome duplication events in Arabidopsis, Oryza, Saccharomyces and TetraodonAndrew H Paterson
Plant Genome Mapping Laboratory and Department of Genetics, University of Georgia, Athens, GA 30602, USA
Trends Genet 22:597-602. 2006..Angiosperms show more frequent polyploidization and a higher degree of duplicate gene preservation than other paleopolyploids, making them well-suited to further study of duplication-resistant genes... - Genomics meets transgenics in search of the elusive Cryptosporidium drug targetBoris Striepen
Center for Tropical and Emerging Global Diseases, University of Georgia, 623 Biological Sciences Building, Athens, GA 30602, USA
Trends Parasitol 20:355-8. 2004..New targets for Cryptosporidium drug and vaccine development can be identified and validated based on this approach... - Gene transfer in the evolution of parasite nucleotide biosynthesisBoris Striepen
Center for Tropical and Emerging Global Diseases and Departments of Cellular Biology, University of Georgia, Athens, GA 30602, USA
Proc Natl Acad Sci U S A 101:3154-9. 2004..Taken together, these data help to explain why widely used drugs fail in the treatment of cryptosporidiosis and suggest more promising targets... - O-glycosylation in Toxoplasma gondii: identification and analysis of a family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferasesMagdalena M Stwora Wojczyk
Department of Genetics, Center for Tropical and Emerging Global Diseases, University of Georgia, 422 Biological Sciences Building, Athens, GA 30602, USA
Int J Parasitol 34:309-22. 2004..Taken together, this information creates the basis for future studies of the function of the ppGalNAc-T gene family in the pathobiology of this apicomplexan parasite... - ApiDB: integrated resources for the apicomplexan bioinformatics resource centerCristina Aurrecoechea
Center for Tropical and Emerging Global Diseases, Athens, GA, USA
Nucleic Acids Res 35:D427-30. 2007..Through the ApiDB site, users may pose queries and search all available apicomplexan data and tools, or they may visit individual component organism databases... - EuPathDB: a portal to eukaryotic pathogen databasesCristina Aurrecoechea
Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA
Nucleic Acids Res 38:D415-9. 2010..Search results are dynamically displayed as the strategy is constructed or modified, and can be downloaded, saved, revised, or shared with other database users... - PlasmoDB: a functional genomic database for malaria parasitesCristina Aurrecoechea
Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA
Nucleic Acids Res 37:D539-43. 2009..Various results can then be combined with each other on the query history page. Search results can be downloaded with associated functional data and registered users can store their query history for future retrieval or analysis... - GiardiaDB and TrichDB: integrated genomic resources for the eukaryotic protist pathogens Giardia lamblia and Trichomonas vaginalisCristina Aurrecoechea
Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA
Nucleic Acids Res 37:D526-30. 2009..Phylogenetic relationships may also be interrogated. The ability to combine the results from independent queries, and to store queries and query results for future use facilitates complex, genome-wide mining of functional genomic data... - ToxoDB: accessing the Toxoplasma gondii genomeJessica C Kissinger
Department of Genetics Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602 2606, USA
Nucleic Acids Res 31:234-6. 2003..the database will provide an integrated data analysis platform facilitating user-defined queries across the different data types... - TcruziDB: an integrated Trypanosoma cruzi genome resourceMichael Luchtan
Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602-2606, USA
Nucleic Acids Res 32:D344-6. 2004..As annotation, microarray and proteomic data become available, the database will incorporate and integrate these data using the GUS (http://www.gusdb. org) relational framework... - The Apicomplexan whole-genome phylogeny: an analysis of incongruence among gene treesChih Horng Kuo
Department of Genetics, University of Georgia, USA
Mol Biol Evol 25:2689-98. 2008..The importance of examining multiple, unlinked genes that possess a strong phylogenetic signal cannot be overstated... - Applied genomics: data mining reveals species-specific malaria diagnostic targets more sensitive than 18S rRNAAllison Demas
Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30602, USA
J Clin Microbiol 49:2411-8. 2011..These novel targets provide a powerful alternative molecular diagnostic method for the detection of P. falciparum and P. vivax in conventional or multiplex PCR platforms... - Mining the Plasmodium genome database to define organellar function: what does the apicoplast do?David S Roos
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104 6018, USA
Philos Trans R Soc Lond B Biol Sci 357:35-46. 2002.... - Determining the protein repertoire of Cryptosporidium parvum sporozoitesSanya J Sanderson
Departments of Pre clinical Veterinary Science and Veterinary Pathology, Faculty of Veterinary Science, University of Liverpool, Liverpool, UK
Proteomics 8:1398-414. 2008..For approximately half the proteome there was limited functional and structural information, highlighting the limitations in the current understanding of Cryptosporidium biology... - PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished)Amit Bahl
Department of Biology, University of Pennsylvania, 415 South University Avenue, Philadelphia, PA 19104-6018, USA
Nucleic Acids Res 30:87-90. 2002..g. by malaria researchers working in the field). The goal of PlasmoDB is to enhance utilization of the vast quantities of data emerging from genome-scale projects by the global malaria research community... - ToxoDB: an integrated Toxoplasma gondii database resourceBindu Gajria
Department of Biology, Department of Genetics, Center for Bioinformatics, University of Pennsylvania, Philadelphia, PA, USA
Nucleic Acids Res 36:D553-6. 2008..ToxoDB has matured significantly since its initial release. Here we outline the numerous updates with respect to the data and increased functionality available on the website... - PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational dataAmit Bahl
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
Nucleic Acids Res 31:212-5. 2003..The software used to develop PlasmoDB has been used to create a second Apicomplexan parasite genome database, ToxoDB (http://ToxoDB.org)... - CryptoDB: the Cryptosporidium genome resourceDaniela Puiu
Center for the Study of Biological Complexity, Virginia Commonwealth University, Richmond, VA, USA
Nucleic Acids Res 32:D329-31. 2004..This database, like other apicomplexan parasite databases, has been built utilizing the PlasmoDB model... - TcruziDB: an integrated, post-genomics community resource for Trypanosoma cruziFernan Aguero
Instituto de Investigaciones Biotecnologicas, Universidad de San Martín San Martín, B 1650 KNA, Buenos Aires, Argentina
Nucleic Acids Res 34:D428-31. 2006..TcruziDB has accepted, and will continue to accept the deposition of genomic and functional genomic datasets contributed by the research community... - Gene discovery in the apicomplexa as revealed by EST sequencing and assembly of a comparative gene databaseLi Li
Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Genome Res 13:443-54. 2003..These genes likely mediate the novel biological features of members of the Apicomplexa and hence offer great potential for biological investigation and as possible therapeutic targets... - Analysis of the first and second internal transcribed spacer sequences of the ribosomal DNA in Biomphalaria tenagophila complex (Mollusca: Planorbidae)Teofânia H D A Vidigal
Centro de Pesquisas Rene Rachou Fiocruz, Av Augusto de Lima, 1715, 30190 002 Belo Horizonte, MG, Brasil
Mem Inst Oswaldo Cruz 99:153-8. 2004..The present results provide support for the proposal that B. tenagophila represents a complex comprising B. tenagophila, B. occidentalis and B. t. guaibensis... - Adaptation of protein secretion to extremely high-salt conditions by extensive use of the twin-arginine translocation pathwayR Wesley Rose
Department of Biology, Leidy Laboratories, University of Pennsylvania, Philadelphia, PA 19104, USA
Mol Microbiol 45:943-50. 2002..This extensive utilization of the Tat pathway in haloarchaea suggests an evolutionary adaptation to high-salt conditions by allowing cytoplasmic folding of secreted proteins before their secretion... - Molecular phylogenetic analysis of the avian malarial parasite Plasmodium (Novyella) juxtanucleareJessica C Kissinger
Centro de Pesquisas René Rachou FIOCRUZ Avenida Augusto de Lima 1715, Barro Preto, Belo Horizonte, Minas Gerais 30190 002, Brazil
J Parasitol 88:769-73. 2002.... - PlasmoDB v5: new looks, new genomesChristian J Stoeckert
Department of Genetics, 1415 Blockley Hall, Center for Bioinformatics, 423 Guardian Drive, University of Pennsylvania, Philadelphia, PA 19104, USA
Trends Parasitol 22:543-6. 2006..This new release includes additional Plasmodium genomes and a newly designed website. The new site reflects the status of PlasmoDB as a member of a linked family of Apicomplexan databases... - The Plasmodium genome databaseJessica C Kissinger
Department of Biology and Genetics, Center for Bioinformatics and Genomics Institute, University of Pennsylvania, Philadelphia, 19104-6018, USA
Nature 419:490-2. 2002
Research Grants
- Genome Evolution, Innovation and Adaptation in the ApicomplexaJessica Kissinger; Fiscal Year: 2007..The results of these studies will be shared with the larger research community via publication and deposition in community databases and Bioinformatics Resource Centers. ..
- Genome Evolution, Innovation and Adaptation in the ApicomplexaJessica Kissinger; Fiscal Year: 2009..The results of these studies will be shared with the larger research community via publication and deposition in community databases and Bioinformatics Resource Centers. ..
- Genome Evolution, Innovation and Adaptation in the ApicomplexaJessica C Kissinger; Fiscal Year: 2010..The results of these studies will be shared with the larger research community via publication and deposition in community databases and Bioinformatics Resource Centers. ..