Irving Kirsch

Summary

Affiliation: University of Connecticut
Country: USA

Publications

  1. ncbi request reprint National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disorders
    Dennis S Charney
    Division of Intramural Research Programs, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 59:262-70. 2002
  2. ncbi request reprint St John's wort, conventional medication, and placebo: an egregious double standard
    I Kirsch
    Department of Psychology, University of Connecticut, Storrs, CT 06269, USA
    Complement Ther Med 11:193-5. 2003
  3. pmc Moving beyond depression: How full is the glass?
    Irving Kirsch
    BMJ 336:629-30. 2008
  4. ncbi request reprint Conditioning, expectancy, and the placebo effect: comment on Stewart-Williams and Podd (2004)
    Irving Kirsch
    Department of Psychology, University of Connecticut, Storrs, CT 06269 1020, USA
    Psychol Bull 130:341-3; discussion 344-5. 2004
  5. ncbi request reprint The role of cognition in classical and operant conditioning
    Irving Kirsch
    University of Connecticut, USA
    J Clin Psychol 60:369-92. 2004
  6. ncbi request reprint Clinical trials and the response rate illusion
    Irving Kirsch
    Psychology, University of Hull, Hull HU6 7RX, United Kingdom
    Contemp Clin Trials 28:348-51. 2007
  7. doi request reprint Consistency of the placebo effect
    Ben Whalley
    School of Psychology, University of Plymouth, Plymouth, UK
    J Psychosom Res 64:537-41. 2008
  8. pmc Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome
    Ted J Kaptchuk
    Osher Research Center, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA
    BMJ 336:999-1003. 2008
  9. doi request reprint Do "placebo responders" exist?
    Ted J Kaptchuk
    Osher Research Center, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA
    Contemp Clin Trials 29:587-95. 2008
  10. pmc Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration
    Irving Kirsch
    Department of Psychology, University of Hull, Hull, United Kingdom
    PLoS Med 5:e45. 2008

Collaborators

Detail Information

Publications16

  1. ncbi request reprint National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disorders
    Dennis S Charney
    Division of Intramural Research Programs, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 59:262-70. 2002
    ..Research is needed on the ethical conduct of studies to limit risks of medication-free intervals and facilitate poststudy treatment. Patients must fully understand the risks and lack of individualized treatment involved in research...
  2. ncbi request reprint St John's wort, conventional medication, and placebo: an egregious double standard
    I Kirsch
    Department of Psychology, University of Connecticut, Storrs, CT 06269, USA
    Complement Ther Med 11:193-5. 2003
    ..Instead they show that hypericum and conventional antidepressants are equally effective (or ineffective). This suggests that different standards are being used to evaluate the two types of treatment...
  3. pmc Moving beyond depression: How full is the glass?
    Irving Kirsch
    BMJ 336:629-30. 2008
  4. ncbi request reprint Conditioning, expectancy, and the placebo effect: comment on Stewart-Williams and Podd (2004)
    Irving Kirsch
    Department of Psychology, University of Connecticut, Storrs, CT 06269 1020, USA
    Psychol Bull 130:341-3; discussion 344-5. 2004
    ..Thus, the higher up the phylogenetic scale, the smaller the role of nonconscious conditioning processes and the larger the role of cognition...
  5. ncbi request reprint The role of cognition in classical and operant conditioning
    Irving Kirsch
    University of Connecticut, USA
    J Clin Psychol 60:369-92. 2004
    ..In this article, the data pertaining to the role of higher-order cognition in conditioning is reviewed, and a theoretical synthesis is proposed that provides a role for both automatic and cognitively mediated processes...
  6. ncbi request reprint Clinical trials and the response rate illusion
    Irving Kirsch
    Psychology, University of Hull, Hull HU6 7RX, United Kingdom
    Contemp Clin Trials 28:348-51. 2007
    ..Response rates based on continuous data do not add information, and they can create an illusion of clinical effectiveness...
  7. doi request reprint Consistency of the placebo effect
    Ben Whalley
    School of Psychology, University of Plymouth, Plymouth, UK
    J Psychosom Res 64:537-41. 2008
    ..For prediction to be possible, the response to placebo must be reliable. We tested the consistency of the placebo effect by assessing the response to four trials of placebo analgesic treatment...
  8. pmc Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome
    Ted J Kaptchuk
    Osher Research Center, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA
    BMJ 336:999-1003. 2008
    ..To assess the relative magnitude of these components...
  9. doi request reprint Do "placebo responders" exist?
    Ted J Kaptchuk
    Osher Research Center, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA
    Contemp Clin Trials 29:587-95. 2008
    ..Finally, this paper proposes one model to rigorously investigate the stability of placebo responses...
  10. pmc Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration
    Irving Kirsch
    Department of Psychology, University of Hull, Hull, United Kingdom
    PLoS Med 5:e45. 2008
    ..The purpose of this analysis is to establish the relation of baseline severity and antidepressant efficacy using a relevant dataset of published and unpublished clinical trials...
  11. ncbi request reprint Placebo analgesia: findings from brain imaging studies and emerging hypotheses
    Jian Kong
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, MA, USA
    Rev Neurosci 18:173-90. 2007
    ..The literature suggests that multiple brain regions, including the anterior cingulate cortex, anterior insula, prefrontal cortex and periaqueductal grey, play a pivotal role in these processes...
  12. ncbi request reprint Investigating placebo effects in irritable bowel syndrome: a novel research design
    Lisa A Conboy
    Osher Institute, Division for Research and Education in Complementary and Integrative Therapies, Harvard Medical School, 401 Park Drive, Suite 22A, Boston, MA 02115, USA
    Contemp Clin Trials 27:123-34. 2006
    ..quot; The trial also uses an innovative combination of quantitative and qualitative methods...
  13. ncbi request reprint Brain activity associated with expectancy-enhanced placebo analgesia as measured by functional magnetic resonance imaging
    Jian Kong
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    J Neurosci 26:381-8. 2006
    ..Our results suggest that placebo analgesia may be configured through multiple brain pathways and mechanisms...
  14. pmc Efficacy of antidepressants in adults
    Joanna Moncrieff
    Department of Mental Health Sciences, University College London, London W1N 8AA
    BMJ 331:155-7. 2005
  15. ncbi request reprint Placebo psychotherapy: synonym or oxymoron?
    Irving Kirsch
    Faculty of Health and Social Work, University of Plymouth, UK
    J Clin Psychol 61:791-803. 2005
    ..The idea of evaluating the efficacy of psychotherapy by controlling for nonspecific or placebo factors is based on a flawed analogy and should be abandoned...
  16. ncbi request reprint Antidepressant drugs 'work', but they are not clinically effective
    Irving Kirsch
    Br J Hosp Med (Lond) 69:359. 2008