J K Kirklin

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Strategies for minimizing hyperlipidemia after cardiac transplantation
    James K Kirklin
    Department of Surgery, Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Am J Cardiovasc Drugs 2:377-87. 2002
  2. doi request reprint Mechanical circulatory support: strategies and outcomes in pediatric congenital heart disease
    James K Kirklin
    Division of Cardiothoracic Surgery, The University of Alabama at Birmingham, Birmingham, AL Electronic address
    Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 17:62-8. 2014
  3. doi request reprint Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) analysis of pump thrombosis in the HeartMate II left ventricular assist device
    James K Kirklin
    University of Alabama at Birmingham, Birmingham, Alabama Electronic address
    J Heart Lung Transplant 33:12-22. 2014
  4. doi request reprint Quantifying the effect of cardiorenal syndrome on mortality after left ventricular assist device implant
    James K Kirklin
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama Electronic address
    J Heart Lung Transplant 32:1205-13. 2013
  5. doi request reprint Fifth INTERMACS annual report: risk factor analysis from more than 6,000 mechanical circulatory support patients
    James K Kirklin
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Heart Lung Transplant 32:141-56. 2013
  6. pmc Long-term mechanical circulatory support (destination therapy): on track to compete with heart transplantation?
    James K Kirklin
    Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Thorac Cardiovasc Surg 144:584-603; discussion 597-8. 2012
  7. doi request reprint Novel technique of valve-sparing aortic root replacement in two children younger than 3 years of age
    James K Kirklin
    Department of Surgery, Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Ann Thorac Surg 94:299-301. 2012
  8. doi request reprint Implantation of the HeartWare HVAD in a child after a recent thromboembolic stroke
    James K Kirklin
    Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Ann Thorac Surg 93:977-8. 2012
  9. doi request reprint The Fourth INTERMACS Annual Report: 4,000 implants and counting
    James K Kirklin
    Division of Cardiovascular, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Heart Lung Transplant 31:117-26. 2012
  10. pmc Surgical strategy to prevent cardiac injury during reoperation in infants
    Christopher J Knott-Craig
    Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Cardiothorac Surg 3:10. 2008

Detail Information

Publications109 found, 100 shown here

  1. ncbi request reprint Strategies for minimizing hyperlipidemia after cardiac transplantation
    James K Kirklin
    Department of Surgery, Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Am J Cardiovasc Drugs 2:377-87. 2002
    ..Consensus exists within the transplant community that a HMG-CoA reductase inhibitor such as pravastatin, should be part of the routine post-transplant drug regimen, and persistent hyperlipidemia should be aggressively treated...
  2. doi request reprint Mechanical circulatory support: strategies and outcomes in pediatric congenital heart disease
    James K Kirklin
    Division of Cardiothoracic Surgery, The University of Alabama at Birmingham, Birmingham, AL Electronic address
    Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 17:62-8. 2014
    ..Several emerging miniature continuous flow devices will soon broaden the landscape of available pediatric devices. ..
  3. doi request reprint Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) analysis of pump thrombosis in the HeartMate II left ventricular assist device
    James K Kirklin
    University of Alabama at Birmingham, Birmingham, Alabama Electronic address
    J Heart Lung Transplant 33:12-22. 2014
    ....
  4. doi request reprint Quantifying the effect of cardiorenal syndrome on mortality after left ventricular assist device implant
    James K Kirklin
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama Electronic address
    J Heart Lung Transplant 32:1205-13. 2013
    ..We analyzed patients from the Interagency Registry for Mechanically Assist Circulatory Support to better estimate postimplant mortality according to the severity of renal dysfunction...
  5. doi request reprint Fifth INTERMACS annual report: risk factor analysis from more than 6,000 mechanical circulatory support patients
    James K Kirklin
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Heart Lung Transplant 32:141-56. 2013
    ..Quality of life indicators are generally favorable and adverse event burden will likely influence patient selections of advanced heart failure therapies...
  6. pmc Long-term mechanical circulatory support (destination therapy): on track to compete with heart transplantation?
    James K Kirklin
    Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Thorac Cardiovasc Surg 144:584-603; discussion 597-8. 2012
    ....
  7. doi request reprint Novel technique of valve-sparing aortic root replacement in two children younger than 3 years of age
    James K Kirklin
    Department of Surgery, Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Ann Thorac Surg 94:299-301. 2012
    ..Follow-up at 2 years in 1 patient and 7 months in a second patient revealed satisfactory valve function with stable aortic root size...
  8. doi request reprint Implantation of the HeartWare HVAD in a child after a recent thromboembolic stroke
    James K Kirklin
    Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Ann Thorac Surg 93:977-8. 2012
    ..After device implantation and intensive physical rehabilitation, the patient underwent successful cardiac transplantation after 60 days of support...
  9. doi request reprint The Fourth INTERMACS Annual Report: 4,000 implants and counting
    James K Kirklin
    Division of Cardiovascular, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Heart Lung Transplant 31:117-26. 2012
    ..Current actuarial survival with continuous-flow pumps exceeds 80% at 1 year and 70% at 2 years...
  10. pmc Surgical strategy to prevent cardiac injury during reoperation in infants
    Christopher J Knott-Craig
    Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Cardiothorac Surg 3:10. 2008
    ..Since few technical options are available for re-entry cardiac injuries in small infants, we postulate that this technique may be equally helpful in those situations...
  11. doi request reprint Is the "perfect Fontan" operation routinely achievable in the modern era?
    James K Kirklin
    Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Cardiol Young 18:328-36. 2008
    ..The objective of this study was to test the hypothesis that a "perfect" outcome is routinely achievable in the current era when using a standardized surgical procedure...
  12. ncbi request reprint Evolving trends in risk profiles and causes of death after heart transplantation: a ten-year multi-institutional study
    J K Kirklin
    University of Alabama at Birmingham, Birmingham, Ala 35293, USA
    J Thorac Cardiovasc Surg 125:881-90. 2003
    ..Results from multi-institutional studies could be used to monitor progress in individual centers...
  13. ncbi request reprint Rejection with hemodynamic compromise: objective evidence for efficacy of photopheresis
    J K Kirklin
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Heart Lung Transplant 25:283-8. 2006
    ..This study examined the hypothesis that photo provides protection against rejection, rejection with hemodynamic compromise (HC), and death from rejection after cardiac transplantation...
  14. doi request reprint Third INTERMACS Annual Report: the evolution of destination therapy in the United States
    James K Kirklin
    Cardiovascular Division, University of Alabama at Birmingham, Alabama 35294, USA
    J Heart Lung Transplant 30:115-23. 2011
    ..The current 1-year survival of 75% with continuous-flow destination therapy provides a benchmark for the evolving application of this therapy...
  15. ncbi request reprint Selection of patients and techniques of heart transplantation
    James K Kirklin
    Department of Surgery, Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Surg Clin North Am 84:257-87, xi-xii. 2004
    ..Patients with multiple comorbidities have inferior survival and might be considered for alternative therapies. We currently recommend the bicaval techniques as the transplant technique of choice except in small infants and children...
  16. ncbi request reprint Mechanical circulatory support therapy as a bridge to transplant or recovery (new advances)
    James K Kirklin
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Curr Opin Cardiol 21:120-6. 2006
    ..These devices offer the potential for smaller operations, greater resistance to infection, and new opportunities for bridge-to-recovery therapy...
  17. ncbi request reprint Is biopsy-proven cellular rejection an important clinical consideration in heart transplantation?
    James K Kirklin
    University of Alabama at Birmingham, Alabama 35294 0007, USA
    Curr Opin Cardiol 20:127-31. 2005
    ....
  18. ncbi request reprint Current outcomes following heart transplantation
    James K Kirklin
    University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Semin Thorac Cardiovasc Surg 16:395-403. 2004
    ..Patient-specific risk profiling will play an increasing role in the allocation of transplantation and other emerging therapies for patients with advanced heart failure...
  19. ncbi request reprint Should status II patients be removed from the pediatric heart transplant waiting list? A multi-institutional study
    J K Kirklin
    University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Heart Lung Transplant 25:271-5. 2006
    ..This study examined the following hypothesis: "Status 2 pediatric recipients have a survival benefit with CTx."..
  20. ncbi request reprint Control of the inflammatory response in extended myocardial preservation of the donor heart
    J K Kirklin
    Department of Surgery, University of Alabama at Birmingham, 35294, USA
    Ann Thorac Surg 68:1978-82. 1999
    ..Knowledge of these basic mechanisms has stimulated the formulation of preservation solutions and strategies to ameliorate the inflammatory response during reperfusion...
  21. ncbi request reprint Utility of posttransplantation panel-reactive antibody measurements for the prediction of rejection frequency and survival of heart transplant recipients
    J F George
    Department of Surgery, University of Alabama at Birmingham 35294 0007, USA
    J Heart Lung Transplant 14:856-64. 1995
    ..A total of 465 panel-reactive antibodies determinations were made during the first year after transplantation...
  22. ncbi request reprint To induce or not to induce: do patients at greatest risk for fatal rejection benefit from cytolytic induction therapy?
    R Higgins
    University of Alabama at Birmingham, Division of Cardiothoracic Surgery, Birmingham, Alabama 35294, USA
    J Heart Lung Transplant 24:392-400. 2005
    ..However, the efficacy of cytolytic agents as induction therapy remains unproven...
  23. ncbi request reprint An essential role for Fas ligand in transplantation tolerance induced by donor bone marrow
    J F George
    Department of Surgery, University of Alabama at Birmingham, 35294 0007, USA
    Nat Med 4:333-5. 1998
    ..Moreover, the results are consistent with the hypothesis that tolerance induced by DBM involves an apoptotic process leading to deletion of graft-reactive cells...
  24. doi request reprint Carbon monoxide-releasing molecule-2 decreases fibrinolysis in human plasma
    Vance G Nielsen
    Department of Anesthesiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA
    Blood Coagul Fibrinolysis 20:448-55. 2009
    ..These findings serve as the rationale for further investigations to determine if carbon monoxide-releasing molecules could be utilized as hemostatic agents...
  25. ncbi request reprint Cardiac transplant outcome of patients supported on left ventricular assist device vs. intravenous inotropic therapy
    B E Jaski
    University of Alabama, Birmingham, Alabama, USA
    J Heart Lung Transplant 20:449-56. 2001
    ..Therefore, patients supported on LVADs before transplant may receive the greatest marginal benefit when compared with other transplant candidates...
  26. ncbi request reprint Gene polymorphisms for plasminogen activator inhibitor-1/tissue plasminogen activator and development of allograft coronary artery disease
    R L Benza
    Department of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham, Alabama, USA
    Circulation 98:2248-54. 1998
    ..Impaired fibrinolytic activity has been linked to the presence and severity of allograft vasculopathy (Tx CAD). This impairment may be associated with the presence of certain fibrinolytic protein gene polymorphisms...
  27. ncbi request reprint Is there a need for surveillance endomyocardial biopsies in heart transplantation?
    J K Kirklin
    Department of Surgery, University of Alabama at Birmingham, 739 Ziegler Building, 703 S 19th Street, Birmingham, AL 35294, USA
    Transplant Proc 34:1857-9. 2002
  28. ncbi request reprint Infection during circulatory support with ventricular assist devices
    W L Holman
    Department of Surgery, University of Alabama at Birmingham, 35294 0007, USA
    Ann Thorac Surg 68:711-6. 1999
    ..This study is a retrospective analysis of infections in patients supported by ventricular assist devices (VADs) as a bridge to cardiac transplantation...
  29. ncbi request reprint An essential role for natural killer cells in augmentation of allograft survival mediated by donor spleen cells
    D R Goldstein
    Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham, 35294-0007, USA
    Transplantation 72:954-6. 2001
    ..In contrast, the extension of graft survival by donor bone marrow does not depend on the presence of donor NK cells...
  30. ncbi request reprint The utility of open lung biopsy following lung transplantation
    D Weill
    Lung Transplant Program, Department of Medicine, University of Alabama Birmingham, Birmingham, Alabama 35294 0006, USA
    J Heart Lung Transplant 19:852-7. 2000
    ..In this study, we reviewed our experience with open lung biopsy (OLB) following lung transplantation, specifically regarding its ability to safely provide clinically relevant information that affects therapeutic decisions...
  31. ncbi request reprint Management of wound and left ventricular assist device pocket infection
    W L Holman
    Department of Medicine, University of Alabama at Birmingham, 35294 0007, USA
    Ann Thorac Surg 68:1080-2. 1999
    ..The wound was revised using rectus muscle to cover the pump. The incisions have healed and the patient is now at home. She is on no systemic antibiotics and has no evidence of infection 11 months postoperatively...
  32. ncbi request reprint The hemostatic history of a 15-month-old child implanted with a Berlin heart left ventricular assist device
    Brad L Steenwyk
    Department of Anesthesiology, The University of Alabama at Birmingham, Birmingham, AL 35294 2172, USA
    Anesth Analg 104:538-40. 2007
    ..In summary, when proscribing anesthetic and surgical management of patients with a Berlin Heart, consideration of hypercoagulable features and anticoagulant therapy must be made to maximize patient safety...
  33. ncbi request reprint Right thoracotomy for mitral reoperation: analysis of technique and outcome
    W L Holman
    Department of Surgery, University of Alabama at Birmingham, 35294 0007, USA
    Ann Thorac Surg 70:1970-3. 2000
    ..Three methods for myocardial management (hypothermic cardioplegic arrest, beating heart, and fibrillating heart) are compared...
  34. ncbi request reprint Indefinite allograft survival mediated by donor bone marrow is dependent on the presence of a functional CD95 (Fas) gene in recipients
    D R Goldstein
    Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294-007, USA
    J Heart Lung Transplant 20:1132-5. 2001
    ..Thus, we conclude that the CD95 ligand-CD95 apoptotic pathway plays a major role in donor bone marrow-induced transplantation tolerance...
  35. doi request reprint Use of an intraperitoneal ventricular assist device with a polytetrafluoroethylene barrier decreases infections
    William L Holman
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294 0007, USA
    J Heart Lung Transplant 27:268-71. 2008
    ..Infection rates for ventricular assist devices (VADs) are improving but the presence of infections remains problematic. Intraperitoneal pump placement may decrease the rate of infection...
  36. ncbi request reprint Images in clinical medicine. Mapping the atrioventricular node
    Andrew E Epstein
    University of Alabama at Birmingham, Birmingham, AL 35294, USA
    N Engl J Med 357:2706. 2007
  37. ncbi request reprint Post-heart transplant diastolic dysfunction is a risk factor for mortality
    Jose A Tallaj
    Department of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama Department of Medicine, Birmingham VA Medical Center, Birmingham, Alabama, USA
    J Am Coll Cardiol 50:1064-9. 2007
    ..The purpose of this study was to evaluate the incidence and prognostic implication of diastolic dysfunction (DD) occurring in the first year after transplant...
  38. ncbi request reprint The Ross operation for aortic valve disease: previous sternotomy results in improved long-term outcome
    Christopher J Knott-Craig
    University of Oklahoma Health Sciences Center, Department of Thoracic and Cardiovascular Surgery, Oklahoma, USA
    J Heart Valve Dis 16:394-7. 2007
    ..The basis for this hypothesis is that the epicardial and mediastinal fibrosis encountered at reoperation may inadvertently provide additional support for the pulmonary autograft during the follow up period...
  39. ncbi request reprint Repair of neonates and young infants with Ebstein's anomaly and related disorders
    Christopher J Knott-Craig
    Department of Thoracic and Cardiovascular Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA
    Ann Thorac Surg 84:587-92; discussion 592-3. 2007
    ..In a recent series, 69% early survival with single-ventricle palliation was reported in 16 neonates with Ebstein's anomaly. Our institutional bias has been to do a two-ventricle repair in all such patients...
  40. pmc Alterations in the fibrinolytic cascade post-transplant: evidence of a bimodal expression pattern
    Raymond L Benza
    Department of Medicine, Division of Cardiovascular Disease, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 0006, USA
    J Heart Lung Transplant 26:494-7. 2007
    ....
  41. ncbi request reprint Thrombelastographic method to quantify the contribution of factor XIII to coagulation kinetics
    Vance G Nielsen
    Department of Anesthesiology, The University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Blood Coagul Fibrinolysis 18:145-50. 2007
    ..Further actuarial investigation will be required to determine the utility of this approach in the diagnosis and treatment of patients with either acquired FXIII deficiency or excess and concordant coagulopathy...
  42. ncbi request reprint Hydroxyethyl starch enhances argatroban-mediated decreases in clot propagation and strength by diminishing thrombin-fibrinogen interactions
    Vance G Nielsen
    Department of Anesthesiology, The University of Alabama at Birmingham, Alabama 35249 6810, USA
    Blood Coagul Fibrinolysis 18:49-54. 2007
    ..Further investigation is warranted to determine whether this therapeutic approach can improve the safety of anticoagulation during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia...
  43. doi request reprint Surfactant treatment for congenital heart disease patients with acute respiratory distress syndrome
    Jeffrey A Alten
    Department of Pediatrics, Division of Critical Care, The University of Alabama, Birmingham, Ala 35233, USA
    Congenit Heart Dis 5:624-8. 2010
    ....
  44. doi request reprint Role for CD4(+)CD25(+) T cells in inhibition of graft rejection by extracorporeal photopheresis
    James F George
    Department of Surgery, University of Alabama at Birmingham, AL 35294, USA
    J Heart Lung Transplant 27:616-22. 2008
    ..We created a mouse model of ECP to determine the effects of ECP on T-cell responses in vivo and the contribution of CD4(+)CD25(+) T cells...
  45. doi request reprint Mechanical circulatory device thrombosis: a new paradigm linking hypercoagulation and hypofibrinolysis
    Vance G Nielsen
    Departments of Anesthesiology, The University of Alabama at Birmingham, Birmingham, Alabama 35249 6810, USA
    ASAIO J 54:351-8. 2008
    ....
  46. doi request reprint Minimizing infection and rejection death: clues acquired from 19 years of multi-institutional cardiac transplantation data
    James F George
    Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham, Alabama 35294, USA
    J Heart Lung Transplant 30:151-7. 2011
    ..The purpose of this study was to estimate the relationship of age, race and gender to rejection and infection across time with respect to age at time of transplant, year of transplantation and immunosuppressive era...
  47. doi request reprint Balancing rejection and infection with respect to age, race, and gender: clues acquired from 17 years of cardiac transplantation data
    James F George
    Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294 0007, USA
    J Heart Lung Transplant 29:966-72. 2010
    ..The contribution of demographic factors, especially age at the time of transplantation to morbidity and mortality due to rejection and infection, is much less well understood...
  48. doi request reprint Device related infections: are we making progress?
    William L Holman
    Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Card Surg 25:478-83. 2010
    ..It is crucial that we continue...
  49. doi request reprint Infection after implantation of pulsatile mechanical circulatory support devices
    William L Holman
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Thorac Cardiovasc Surg 139:1632-1636.e2. 2010
    ..This analysis uses INTERMACS data to define the time course, incidence, and outcome of infection adverse events focusing on the first 3 months after implant...
  50. pmc Coronary artery fistula ligation in a child with use of the Starfish Heart Positioner
    F Bennett Pearce
    Department of Pediatrics, University of Alabama School of Medicine, Birmingham, Alabama 35249 6852, USA
    Tex Heart Inst J 36:459-61. 2009
    ..The patient was discharged from the hospital 2 days postoperatively. Six weeks later, she was well, and echocardiography showed no residual fistulous flow...
  51. doi request reprint INTERMACS: interval analysis of registry data
    William L Holman
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35294 0007, USA
    J Am Coll Surg 208:755-61; discussion 761-2. 2009
    ..INTERMACS data were analyzed through the most recent quarter ending March 31, 2008...
  52. doi request reprint Safety and efficacy of ibutilide in heart transplant recipients
    Jose A Tallaj
    Division of Cardiovascular Disease, Section of Heart Failure, Transplantation and Pulmonary Vascular Disease, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Heart Lung Transplant 28:505-7. 2009
    ..Ibutilide treatment was successful in all patients, with the arrhythmia recurring early in 1 patient. There were no complications...
  53. doi request reprint Predictors of death and transplant in patients with a mechanical circulatory support device: a multi-institutional study
    William L Holman
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294 0007, USA
    J Heart Lung Transplant 28:44-50. 2009
    ..This study identifies predictors for death and transplantation based on initial results from INTERMACS...
  54. doi request reprint Clot lifespan model analysis of the effects of warfarin on thrombus growth and fibrinolysis: role of contact protein and tissue factor initiation
    Vance G Nielsen
    Department of Anesthesiology, The University of Alabama at Birmingham, Birmingham, Alabama 35249 6810, USA
    ASAIO J 55:33-40. 2009
    ..Only the time to maximum rate of lysis was correlated with INR (r=0.36, p=0.005). INR values have little correlation with the difference between contact protein and TF-activated coagulation/fibrinolysis...
  55. doi request reprint Patency of internal jugular vein following repair after ECMO stabilization prior to Berlin Heart implantation: utility of repaired vein for subsequent cardiac catheterization and biopsy
    Frank Bennett Pearce
    Division of Pediatric Cardiology, University of Alabama, School of Medicine, Birmingham, AL, USA
    Congenit Heart Dis 3:411-4. 2008
    ..The objective of this study was to examine the patency and utility for subsequent vascular access of the internal jugular vein following use in short-term extracorporeal membrane oxygenation...
  56. doi request reprint Argatroban enhances fibrinolysis by differential inhibition of thrombin-mediated activation of thrombin activatable fibrinolysis inhibitor and factor XIII
    Vance G Nielsen
    Department of Anesthesiology, The University of Alabama at Birmingham, Birmingham, Alabama 35249 6810, USA
    Blood Coagul Fibrinolysis 19:793-800. 2008
    ..The mechanism by which argatroban more efficiently enhanced fibrinolysis was via a differential inhibition of thrombin-mediated activation of TAFI and FXIII...
  57. doi request reprint Patient with hypofibrinolysis-mediated thromboembolism converted to a hypercoagulable/hyperfibrinolytic state via ventricular assist device placement
    Vance G Nielsen
    Department of Anesthesiology, University of Alabama at Birmingham, Birmingham, Alabama 35249 6810, USA
    J Heart Lung Transplant 27:1169-71. 2008
    ..Such complex patient-VAD-hemostatic-state interactions serve as the rationale for continuing investigation of the effects of mechanical circulation on the fibrinolytic system and thrombophilia...
  58. ncbi request reprint Argatroban, bivalirudin, and lepirudin do not decrease clot propagation and strength as effectively as heparin-activated antithrombin in vitro
    Vance G Nielsen
    Department of Anesthesiology, The University of Alabama at Birmingham, Birmingham, Alabama 35249 6810, USA
    J Heart Lung Transplant 25:653-63. 2006
    ..An in vitro thrombelastographic assessment of the effects of DTIs on clot kinetics was consequently performed to determine potential causes for this complication...
  59. ncbi request reprint The intensive care unit oxygen challenge should not be used for donor lung function decision-making
    David C McGiffin
    Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Heart Lung Transplant 24:1902-5. 2005
    ..An arterial PO2 of <300 mm Hg is generally considered evidence of inadequate pulmonary function that contraindicates the use of the lungs for transplantation...
  60. ncbi request reprint Sternal approximation for bilateral anterolateral transsternal thoracotomy for lung transplantation
    David C McGiffin
    Division of Cardiovascular and Thoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294 0007, USA
    Ann Thorac Surg 79:e19-20. 2005
    ....
  61. ncbi request reprint Managing device infections: are we progressing or is infection an insurmountable obstacle?
    William L Holman
    Department of Surgery, University of Alabama at Birmingham, Birmingham AL, USA
    ASAIO J 51:452-5. 2005
    ....
  62. ncbi request reprint Multi-organ transplantation: is there a protective effect against acute and chronic rejection?
    Laura J Pinderski
    Division of Cardiology, Department of Medicine, University of Alabama, Birmingham, Alabama 35294 0006, USA
    J Heart Lung Transplant 24:1828-33. 2005
    ..This study was undertaken to evaluate acute and chronic heart and/or lung rejection in the setting of multiple-transplanted organs from the same donor compared with single-organ transplantation...
  63. ncbi request reprint Palliation of allograft vasculopathy with transluminal angioplasty: a decade of experience
    Raymond L Benza
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 0006, USA
    J Am Coll Cardiol 43:1973-81. 2004
    ..The goal of this study was to examine the outcomes of percutaneous coronary interventions (PCI) and the predictors for restenosis after cardiac transplantation...
  64. ncbi request reprint Allogeneic bone marrow inhibits T-cell activation and clonal expansion in vitro
    James F George
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35294 0007, USA
    Transplantation 76:237-43. 2003
    ..However, the mechanisms through which bone marrow cells affect tolerance remain obscure. We studied the affect of allogeneic bone marrow cells on the activation of allospecific T cells in vitro...
  65. ncbi request reprint Of mice and men: mouse models and the molecular mechanisms of post-transplant coronary artery disease
    James F George
    Division of Cardiothoracic Surgery, Department of Surgery, The University of Alabama at Birmingham, Birmingham, Alabama 35294 0007, USA
    J Heart Lung Transplant 24:2003-14. 2005
  66. ncbi request reprint Infection in ventricular assist devices: prevention and treatment
    William L Holman
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294 0007, USA
    Ann Thorac Surg 75:S48-57. 2003
    ..This paper describes the pathogenesis of MCSS infection, with particular attention to the role of biofilm-forming bacteria. Suggestions are presented for the prevention and treatment of infections in implanted MCSS...
  67. ncbi request reprint Hemodynamic evaluation of normally functioning Sulzer Carbomedics prosthetic valves
    Nurgul Keser
    Division of Cardiovascular Disease, The University of Alabama at Birmingham, Birmingham, AL, USA
    Ultrasound Med Biol 29:649-57. 2003
    ..Valve regurgitation as evaluated by color Doppler flow mapping was mild in practically all CPs in the aortic position, and in the majority of CPs in the mitral position...
  68. ncbi request reprint Treatment of end-stage heart disease with outpatient ventricular assist devices
    William L Holman
    Department of Surgery, University of Alabama at Birmingham, 35294 0007, USA
    Ann Thorac Surg 73:1489-93; discussion 1493-4. 2002
    ..This article reviews our experience with VAD therapy from the start of our outpatient program until the present...
  69. ncbi request reprint Pulmonary transplantation for advanced bronchioloalveolar carcinoma
    George L Zorn
    Departments of Surgery, The University of Alabama at Birmingham, Birmingham, Ala 35294 0016, USA
    J Thorac Cardiovasc Surg 125:45-8. 2003
    ..No effective therapy is currently available for the diffuse stage of bronchioloalveolar carcinoma...
  70. ncbi request reprint The case for selective re-issuance of medical certificates to allow pilots who have received a heart transplant to resume flying
    David C McGiffin
    University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Heart Lung Transplant 24:259-69. 2005
    ....
  71. ncbi request reprint Cardiac transplant patients response to the (31)P MRS stress test
    William T Evanochko
    Center for NMR Research and Development and the Department of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Heart Lung Transplant 21:522-9. 2002
    ..If transient ischemia is invoked through the (31)P magnetic resonance spectroscopy (MRS) stress test, monitoring of such an event should be achievable and thus implicating possible ischemic involvement...
  72. ncbi request reprint A positive donor gram stain does not predict outcome following lung transplantation
    David Weill
    Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 0006, USA
    J Heart Lung Transplant 21:555-8. 2002
    ..Many potential lung donors are excluded on the basis of a positive donor gram stain (DGS). We examined the association between a positive DGS and the probability of post-operative recipient pneumonia in the first 30 days...
  73. ncbi request reprint Glucose-insulin-potassium infusion for myocardial protection during off-pump coronary artery surgery
    William A Lell
    Department of Anesthesiology, The University of Alabama at Birmingham, 35249 6810, USA
    Ann Thorac Surg 73:1246-51; discussion 1251-2. 2002
    ....
  74. ncbi request reprint Usefulness of transesophageal three-dimensional echocardiography in the identification of individual segment/scallop prolapse of the mitral valve
    Sujood Ahmed
    Division of Cardiovascular Diseases, Heart Station SWB S102, University of Alabama at Birmingham, 619 19th Street South, Birmingham, AL 35249, USA
    Echocardiography 20:203-9. 2003
    ..It may also be potentially useful in assessing the extent of individual scallop/segment prolapse and identifying sites of MV noncoaptation. This information could aid the surgeon in deciding the extent of MV resection...
  75. doi request reprint Bradycardia and syncope as a presentation of cardiac allograft rejection involving the conducting system
    Carrie S Knight
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA
    Cardiovasc Pathol 19:117-20. 2010
    ..We postulate that aggressive therapy for rejection and pacemaker placement may result in improved survival in heart transplant recipients with this clinical presentation...
  76. doi request reprint Carbon monoxide releasing molecule-2 increases the velocity of thrombus growth and strength in human plasma
    Vance G Nielsen
    Department of Anesthesiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA
    Blood Coagul Fibrinolysis 20:377-80. 2009
    ..Carbon monoxide and iCORM-2 derived from CORM-2 markedly enhance the velocity of clot growth and strength. These findings serve as the rationale for further investigations to determine if CORMs could be utilized as hemostatic agents...
  77. ncbi request reprint Combination prophylaxis with ganciclovir and cytomegalovirus (CMV) immune globulin after lung transplantation: effective CMV prevention following daclizumab induction
    David Weill
    Department of Medicine and Cardiothoracic Surgery, Veterans Administration Medical Center, University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Transplant 3:492-6. 2003
    ..Longer follow-up will be needed to evaluate the impact of combination therapy on the incidence of bronchiolitis obliterans syndrome (BOS)...
  78. doi request reprint Carbon monoxide releasing molecule-2 increases the velocity of thrombus growth and strength in hemophilia A, hemophilia B and factor VII-deficient plasmas
    Vance G Nielsen
    Department of Anesthesiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA
    Blood Coagul Fibrinolysis 21:41-5. 2010
    ..CORM-2 markedly enhanced the velocity of clot growth and strength in hemophiliac plasma. These findings serve as the rationale to determine whether CORMs could be utilized as hemostatic agents...
  79. ncbi request reprint Mechanical circulatory support for myocarditis: how much recovery should occur before device removal?
    James E Davies
    Department of Surgery, University of Alabama at Birmingham, 35294, USA
    J Heart Lung Transplant 21:1246-9. 2002
    ..This case report serves as the basis for a discussion of criteria for deciding when to terminate mechanical circulatory support in a patient with recovery after acute myocarditis...
  80. ncbi request reprint Live three-dimensional transthoracic echocardiographic delineation of patent ductus arteriosus
    Ashish Sinha
    Division of Cardiovascular Disease, University of Alabama at Birmingham, 35294, USA
    Echocardiography 21:443-8. 2004
    ..We report an adult patient with a patent ductus arteriosus in whom live three-dimensional transthoracic echocardiography provided comprehensive assessment of the morphology and pathophysiology of the lesion...
  81. ncbi request reprint Native aortic valve insufficiency in patients with left ventricular assist devices
    Ayesha S Bryant
    Department of Surgery, University of Alabama, Birmingham, Alabama, USA
    Ann Thorac Surg 81:e6-8. 2006
    ..Two of the repairs have been durable for more than 1 year and aspirin appears to be sufficient anticoagulation...
  82. ncbi request reprint Intraoperative transesophageal echocardiographic diagnosis of a stuck bioprosthetic mitral valve leaflet
    Anurag Singh
    Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Echocardiography 24:436-8. 2007
    ..We describe the first case of a stuck bioprosthetic mitral valve leaflet in which intraoperative transesophageal echocardiography was useful to make a definitive diagnosis and helped to resolve the problem immediately...
  83. ncbi request reprint Self-report measures among transplant candidates: the impact of evaluative situations
    J D Putzke
    Medical Psychology Program, University of Alabama at Birmingham, 35249, USA
    Assessment 8:19-35. 2001
    ..Social desirability was significantly related to change in self-reported anxiety and depression across conditions, but was unrelated to change in endorsement of personality characteristics...
  84. ncbi request reprint Management of congenital abnormalities of the donor lung
    F Schmidt
    Division of Cardiothoracic Surgery, University of Alabama at Birmingham, USA
    Ann Thorac Surg 72:935-7. 2001
    ....
  85. ncbi request reprint Initial experience with live/real time three-dimensional transesophageal echocardiography
    Koteswara R Pothineni
    Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Echocardiography 24:1099-104. 2007
    ..This important technology promises improved anatomic definition, diagnostic confidence, and novel views of the complicated cardiovascular pathology encountered in common clinical practice...
  86. ncbi request reprint Usefulness of live/real time three-dimensional transthoracic echocardiography in the characterization of ventricular septal defects in adults
    Farhat Mehmood
    Division of Cardiovascular Diseases, University of Alabama at Birmingham, Alabama 35249, USA
    Echocardiography 23:421-7. 2006
    ..Live/real time 3DTTE accurately defined VSD location, size, and surrounding anatomy in all patients studied by us. VSD characterization by live 3DTTE agreed well with surgery descriptions and 3DTEE measurements...
  87. ncbi request reprint Transesophageal echocardiographic diagnosis of aortic arch-left innominate vein fistula
    Srinivas Vengala
    Division of Cardiovascular Diseases, The University of Alabama at Birmingham, Birmingham, Alabama, USA
    Echocardiography 22:43-5. 2005
    ..The patient subsequently underwent successful surgical repair of the fistula...
  88. ncbi request reprint Quantification of mitral regurgitation by live three-dimensional transthoracic echocardiographic measurements of vena contracta area
    Deepak Khanna
    Division of Cardiovascular Diseases, The University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Echocardiography 21:737-43. 2004
    ..51 and rs=0.55, respectively). Live 3D TTE color Doppler measurements of VCA can be used for quantitative assessment of MR and is comparable to assessment by ventriculography...
  89. ncbi request reprint Outcomes of children bridged to heart transplantation with ventricular assist devices: a multi-institutional study
    Elizabeth D Blume
    Department of Cardiology, Children s Hospital Boston, Boston, MA 02115, USA
    Circulation 113:2313-9. 2006
    ..Current ventricular assist devices (VADs) in the United States are designed primarily for adult use. Data on VADs as a bridge to transplantation in children are limited...
  90. pmc Patterns and predictors of quality of life at 5 to 10 years after heart transplantation
    Kathleen L Grady
    Northwestern Memorial Hospital, Chicago, Illinois, USA
    J Heart Lung Transplant 26:535-43. 2007
    ..The purposes of our study were to describe QOL over time and identify predictors of QOL longitudinally from 5 to 10 years after heart transplantation...
  91. ncbi request reprint Scientific Registry of the International Society for Heart and Lung Transplantation: introduction to the 2005 annual reports
    Marshall I Hertz
    International Society for Heart and Lung Transplantation, Addison, Texas, USA
    J Heart Lung Transplant 24:939-44. 2005
  92. ncbi request reprint Thrombelastographic measures of clot propagation: a comparison of alpha with the maximum rate of thrombus generation
    Truitt C Ellis
    Department of Anesthesiology, The University of Alabama at Birmingham, Alabama 35249 6810, USA
    Blood Coagul Fibrinolysis 18:45-8. 2007
    ..The MRTG should be progressively utilized to a greater extent in both laboratory and clinical settings to parametrically quantify clot growth kinetics with thrombelastography...
  93. ncbi request reprint Long-term outcomes of cardiac transplantation for peri-partum cardiomyopathy: a multiinstitutional analysis
    Kismet D Rasmusson
    UTAH Cardiac Transplant Program, LDS Hospital, Salt Lake City, Utah 84143, USA
    J Heart Lung Transplant 26:1097-104. 2007
    ..Outcomes of patients with a prior diagnosis of peri-partum cardiomyopathy (PPCM) undergoing heart transplantation are not well described but may be worse than for women who undergo transplantation for other etiologies...
  94. ncbi request reprint Late rejection episodes more than 1 year after pediatric heart transplantation: risk factors and outcomes
    Steven A Webber
    Department of Pediatrics, Pittsburgh Children s Hospital, Pittsburgh, Pennsylvania 15213, USA
    J Heart Lung Transplant 22:869-75. 2003
    ..We determined the frequency of late rejection episodes (>1 year) after pediatric heart transplantation, defined risk factors for its occurrence, and evaluated outcome after late rejection...
  95. ncbi request reprint Risk factors for recurrent rejection in pediatric heart transplantation: a multicenter experience
    Clifford Chin
    Division of Pediatric Cardiology, Stanford University, Palo Alto, California 94304, USA
    J Heart Lung Transplant 23:178-85. 2004
    ..We sought to quantify the time-related probability of recurrent rejection and identify risk factors for the development of recurrent rejection...
  96. doi request reprint Genetic polymorphisms impact the risk of acute rejection in pediatric heart transplantation: a multi-institutional study
    Diana M Girnita
    Department of Pathology, Thomas E Starzl Transplant Institute, University of Pittsburgh, PA, USA
    Transplantation 85:1632-9. 2008
    ....
  97. ncbi request reprint Mechanical circulatory support device database of the International Society for Heart and Lung Transplantation: third annual report--2005
    Mario C Deng
    International Society for Heart and Lung Transplantation, Addison, Texas, USA
    J Heart Lung Transplant 24:1182-7. 2005
  98. ncbi request reprint Mechanical Circulatory Support Device Database of the International Society for Heart and Lung Transplantation: second annual report--2004
    Mario C Deng
    International Society for Heart and Lung Transplantation, Addison, Texas, USA
    J Heart Lung Transplant 23:1027-34. 2004
  99. ncbi request reprint Consensus conference report: maximizing use of organs recovered from the cadaver donor: cardiac recommendations, March 28-29, 2001, Crystal City, Va
    Jonathan G Zaroff
    UCSF Medical Center, San Francisco, Calif 94143 0124, USA
    Circulation 106:836-41. 2002
    ....
  100. doi request reprint Lessons learned from the pediatric heart transplant study
    Daphne T Hsu
    Department of Pediatrics, Columbia University, New York, NY, USA
    Congenit Heart Dis 1:54-62. 2006
    ....
  101. ncbi request reprint Ventricular assist devices as a bridge to heart transplantation in children
    Heather J Bastardi
    Department of Cardiology, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    J Cardiovasc Nurs 23:25-9. 2008
    ..This retrospective study analyzed the clinical features and outcomes of 99 pediatric patients who underwent VAD implant as a bridge to heart transplant...