Levent Kirisci

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Longitudinal modeling of transmissible risk in boys who subsequently develop cannabis use disorder
    Levent Kirisci
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Drug Alcohol Abuse 39:180-5. 2013
  2. pmc Age of alcohol and cannabis use onset mediates the association of transmissible risk in childhood and development of alcohol and cannabis disorders: evidence for common liability
    Levent Kirisci
    Department of Pharmaceutical Sciences, University of Pittsburgh, PA 15213, USA
    Exp Clin Psychopharmacol 21:38-45. 2013
  3. pmc Quick screen to detect current substance use disorder in adolescents and the likelihood of future disorder
    Levent Kirisci
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, School of Pharmacy, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 128:116-22. 2013
  4. pmc Computer adaptive testing of liability to addiction: identifying individuals at risk
    Levent Kirisci
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, 3520 Forbes Avenue, Suite 203, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 123:S79-86. 2012
  5. ncbi request reprint Impact of parental substance use disorder and child neglect severity on substance use involvement in male offspring
    L Kirisci
    Department of Pharmaceutical Sciences, University of Pittsburgh, Pennsylvania 15261, USA
    Prev Sci 2:241-55. 2001
  6. pmc Prediction of cannabis use disorder between boyhood and young adulthood: clarifying the phenotype and environtype
    Levent Kirisci
    Center for Education and Drug Abuse Research, University of Pittsburgh, School of Pharmacy, Pittsburgh, Pennsylvania 15261, USA
    Am J Addict 18:36-47. 2009
  7. pmc Screening current and future diagnosis of psychiatric disorders using the Revised Drug Use Screening Inventory
    Levent Kirisci
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Drug Alcohol Abuse 34:653-65. 2008
  8. ncbi request reprint Individual differences in childhood neurobehavior disinhibition predict decision to desist substance use during adolescence and substance use disorder in young adulthood: a prospective study
    Levent Kirisci
    Center for Education and Drug Abuse Research, University of Pittsburgh, PA 15261, USA
    Addict Behav 31:686-96. 2006
  9. ncbi request reprint Detection of youth at high risk for substance use disorders: a longitudinal study
    Levent Kirisci
    School of Pharmacy, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
    Psychol Addict Behav 19:243-52. 2005
  10. ncbi request reprint Developmental trajectory classes in substance use disorder etiology
    Levent Kirisci
    University of Pittsburgh, School of Pharmacy, Pittsburgh, PA 15261, USA
    Psychol Addict Behav 21:287-96. 2007

Research Grants

Detail Information

Publications71

  1. pmc Longitudinal modeling of transmissible risk in boys who subsequently develop cannabis use disorder
    Levent Kirisci
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Drug Alcohol Abuse 39:180-5. 2013
    ..Risk for substance use disorder is frequently transmitted across generations due to significant heritability...
  2. pmc Age of alcohol and cannabis use onset mediates the association of transmissible risk in childhood and development of alcohol and cannabis disorders: evidence for common liability
    Levent Kirisci
    Department of Pharmaceutical Sciences, University of Pittsburgh, PA 15213, USA
    Exp Clin Psychopharmacol 21:38-45. 2013
    ..TLI predicts age of first use of alcohol and cannabis that is common to developing both AUD and CUD. The ramifications of these findings for prevention are discussed...
  3. pmc Quick screen to detect current substance use disorder in adolescents and the likelihood of future disorder
    Levent Kirisci
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, School of Pharmacy, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 128:116-22. 2013
    ..A brief screen requiring 3-4min administration time was developed to detect adolescents qualifying for current substance use disorder (SUD) and those who will subsequently manifest SUD by early adulthood...
  4. pmc Computer adaptive testing of liability to addiction: identifying individuals at risk
    Levent Kirisci
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, 3520 Forbes Avenue, Suite 203, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 123:S79-86. 2012
    ..This study was conducted to develop and evaluate a computer adaptive test (CAT) version of the TLI to identifying individuals at risk for SUD...
  5. ncbi request reprint Impact of parental substance use disorder and child neglect severity on substance use involvement in male offspring
    L Kirisci
    Department of Pharmaceutical Sciences, University of Pittsburgh, Pennsylvania 15261, USA
    Prev Sci 2:241-55. 2001
    ....
  6. pmc Prediction of cannabis use disorder between boyhood and young adulthood: clarifying the phenotype and environtype
    Levent Kirisci
    Center for Education and Drug Abuse Research, University of Pittsburgh, School of Pharmacy, Pittsburgh, Pennsylvania 15261, USA
    Am J Addict 18:36-47. 2009
    ....
  7. pmc Screening current and future diagnosis of psychiatric disorders using the Revised Drug Use Screening Inventory
    Levent Kirisci
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Drug Alcohol Abuse 34:653-65. 2008
    ..Thus in addition to its utility for detecting problems that precede and correlate with substance abuse, the DUSI-R is cost-efficient for screening youths for mental disorders...
  8. ncbi request reprint Individual differences in childhood neurobehavior disinhibition predict decision to desist substance use during adolescence and substance use disorder in young adulthood: a prospective study
    Levent Kirisci
    Center for Education and Drug Abuse Research, University of Pittsburgh, PA 15261, USA
    Addict Behav 31:686-96. 2006
    ..The findings indicate that substance abuse prevention would be potentiated by ameliorating childhood neurobehavior disinhibition...
  9. ncbi request reprint Detection of youth at high risk for substance use disorders: a longitudinal study
    Levent Kirisci
    School of Pharmacy, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
    Psychol Addict Behav 19:243-52. 2005
    ..These results indicate that monitoring social adjustment during the transition from childhood to mid-adolescence is important for identifying youth at very high risk for succumbing to SUD by young adulthood...
  10. ncbi request reprint Developmental trajectory classes in substance use disorder etiology
    Levent Kirisci
    University of Pittsburgh, School of Pharmacy, Pittsburgh, PA 15261, USA
    Psychol Addict Behav 21:287-96. 2007
    ....
  11. ncbi request reprint Application of item response theory to quantify substance use disorder severity
    Levent Kirisci
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Addict Behav 31:1035-49. 2006
    ....
  12. ncbi request reprint Relation between cognitive distortions and neurobehavior disinhibition on the development of substance use during adolescence and substance use disorder by young adulthood: a prospective study
    Levent Kirisci
    Center for Education and Drug Abuse Research CEDAR, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Drug Alcohol Depend 76:125-33. 2004
    ....
  13. pmc The Violence Proneness Scale of the DUSI-R predicts adverse outcomes associated with substance abuse
    Levent Kirisci
    Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Addict 18:173-7. 2009
    ..Prediction accuracy ranged between 62%-83%. These findings suggest that the VPS may be useful for identifying youths who are at high risk for using illicit drugs and commonly associated adverse outcomes...
  14. pmc Prospective study of the association between neurobehavior disinhibition and peer environment on illegal drug use in boys and girls
    Levent Kirisci
    School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Drug Alcohol Abuse 35:145-50. 2009
    ..Objectives: Male and female children and adolescents were compared to determine the relative influence of individual susceptibility (neurobehavior disinhibition or ND) and social environment (deviancy in peers) on use of illegal drugs...
  15. ncbi request reprint Item response theory modeling of substance use: an index based on 10 drug categories
    Levent Kirisci
    Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, 707 Salk Hall, Pittsburgh, Pennsylvania 15261, USA
    Psychol Addict Behav 16:290-8. 2002
    ..Finally, this index is a reliable and useful prognostic indicator of the risk for SUD and the medical and psychosocial sequelae of drug consumption...
  16. pmc Measurement of the risk for substance use disorders: phenotypic and genetic analysis of an index of common liability
    Michael M Vanyukov
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Behav Genet 39:233-44. 2009
    ..The data suggest a high heritability of the index in males. The results suggest applicability of the method for genetic and other etiology-related research, and for evaluation of individual risk...
  17. pmc Does the "gateway" sequence increase prediction of cannabis use disorder development beyond deviant socialization? Implications for prevention practice and policy
    Ralph E Tarter
    Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15213, United States
    Drug Alcohol Depend 123:S72-8. 2012
    ..e., consuming legal drugs before cannabis, or the reverse) increases accuracy of prediction of cannabis use disorder...
  18. pmc Prospective study of the association between abandoned dwellings and testosterone level on the development of behaviors leading to cannabis use disorder in boys
    Ralph E Tarter
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, School of Pharmacy, Pittsburgh, PA 15261, USA
    Biol Psychiatry 65:116-21. 2009
    ..It was theorized that adverse neighborhood correlates with testosterone level that in turn potentiates behaviors predisposing to cannabis consumption and subsequently diagnosis of cannabis use disorder...
  19. ncbi request reprint Neurobehavioral disinhibition in childhood predicts early age at onset of substance use disorder
    Ralph E Tarter
    University of Pittsburgh, Department of Pharmaceutical Sciences, Pittsburgh, PA 15261, USA
    Am J Psychiatry 160:1078-85. 2003
    ....
  20. pmc Neurobehavior disinhibition, parental substance use disorder, neighborhood quality and development of cannabis use disorder in boys
    Ty A Ridenour
    Center for Education and Drug Abuse Research, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Drug Alcohol Depend 102:71-7. 2009
    ..The implications of this pattern of association between parental SUD, neighborhood context and individual risk for SUD for improving prevention are discussed...
  21. pmc Deviant socialization mediates transmissible and contextual risk on cannabis use disorder development: a prospective study
    Ralph E Tarter
    University of Pittsburgh, Department of Pharmaceutical Sciences, Pittsburgh, PA 15261, USA
    Addiction 106:1301-8. 2011
    ..This study examined the contribution of transmissible risk, in conjunction with family and peer contextual factors during childhood and adolescence, on the development of cannabis use disorder in adulthood...
  22. doi request reprint Peer environment mediates parental history and individual risk in the etiology of cannabis use disorder in boys: a 10-year prospective study
    Ulrike Feske
    Center for Education and Drug Abuse Research CEDAR, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Drug Alcohol Abuse 34:307-20. 2008
    ..Peer environment mediated the association between ND and cannabis use and ND and CUD. Maternal and paternal SUD predicted the peer environment. Parental SUD, son's ND, and son's peer environment predicted CUD at age 22 with 84% accuracy...
  23. ncbi request reprint Reciprocal influence of parent discipline and child's behavior on risk for substance use disorder: a nine-year prospective study
    Ada C Mezzich
    School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Drug Alcohol Abuse 33:851-67. 2007
    ....
  24. pmc Physical maturation, peer environment, and the ontogenesis of substance use disorders
    Galina P Kirillova
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15261, USA
    Psychiatry Res 158:43-53. 2008
    ..The data support the hypothesis that parental SUD liability influences the rate of physiological maturation in offspring, which in turn is related to affiliation with deviant peers and an elevated rate of the development of CD and SUD...
  25. ncbi request reprint Predictors of marijuana use in adolescents before and after licit drug use: examination of the gateway hypothesis
    Ralph E Tarter
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261, USA
    Am J Psychiatry 163:2134-40. 2006
    ..They also evaluated the accuracy of the "gateway sequence" (illicit drug use following licit drugs) for predicting a diagnosis of substance use disorder...
  26. ncbi request reprint Borderline personality and substance use in women
    Ulrike Feske
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Addict 15:131-7. 2006
    ..Antisocial personality disorder generally yielded larger odds ratios than BPD and emerged as a partial mediator of the relation between BPD and SUD. Histrionic PD was the only other PD that showed meaningful relations with SUD...
  27. pmc Relation among HPA and HPG neuroendocrine systems, transmissible risk and neighborhood quality on development of substance use disorder: results of a 10-year prospective study
    Ralph E Tarter
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, 3520 Forbes Avenue, Parkvale Annex, 2nd Floor, Pittsburgh, PA 15213, United States
    Drug Alcohol Depend 127:226-31. 2013
    ....
  28. pmc Parental supervision and alcohol use in adolescence: developmentally specific interactions
    Duncan B Clark
    Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Dev Behav Pediatr 29:285-92. 2008
    ..This study examined the interaction of parental supervision and adolescent alcohol use from late childhood through middle adolescence...
  29. ncbi request reprint Childhood neurobehavior disinhibition amplifies the risk of substance use disorder: interaction of parental history and prenatal alcohol exposure
    Kim Chapman
    Department of Pediatrics, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
    J Dev Behav Pediatr 28:219-24. 2007
    ..The extent to which ND predicted SUD outcome 7 to 9 years later was also determined...
  30. ncbi request reprint Liability to substance use disorders: 2. A measurement approach
    Michael M Vanyukov
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
    Neurosci Biobehav Rev 27:517-26. 2003
    ..This method is also applicable to measuring liabilities to other complex disorders, especially those with relatively late onset...
  31. ncbi request reprint Testosterone levels and sexual maturation predict substance use disorders in adolescent boys: a prospective study
    Maureen D Reynolds
    Center for Education and Drug Abuse Research, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania 15261, USA
    Biol Psychiatry 61:1223-7. 2007
    ..This investigation determined whether testosterone level and sexual maturation in boys biased development of socially nonnormative behavior culminating in a substance use disorder (SUD)...
  32. ncbi request reprint Neurobehavior disinhibition in childhood predicts suicide potential and substance use disorder by young adulthood
    R E Tarter
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Drug Alcohol Depend 76:S45-52. 2004
    ..These results are discussed within a neurobehavioral framework in which prefrontal cortex dysfunction is hypothesized to underlie the risk for these two outcomes...
  33. ncbi request reprint Predicting adolescent violence: impact of family history, substance use, psychiatric history, and social adjustment
    Ralph E Tarter
    Department of Pharmaceutical Sciences, University of Pittsburgh, PA 15261, USA
    Am J Psychiatry 159:1541-7. 2002
    ..In addition, the authors sought to use this screening instrument, in conjunction with child and parent psychopathology and substance abuse data, to determine the accuracy of violent outcome predictions...
  34. pmc High and low neurobehavior disinhibition clusters within locales: implications for community efforts to prevent substance use disorder
    Ty A Ridenour
    School of Pharmacy, Center for Education and Drug Abuse Research, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Drug Alcohol Abuse 39:194-203. 2013
    ..Identifying locales characterized by high childhood neurobehavioral disinhibition (ND), a strong predictor of substance use and consequent disorder (SUD), may likewise improve prevention efforts...
  35. pmc Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective
    Michael M Vanyukov
    Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USA
    Drug Alcohol Depend 123:S3-17. 2012
    ..Two competing concepts address the development of involvement with psychoactive substances: the "gateway hypothesis" (GH) and common liability to addiction (CLA)...
  36. pmc Could a continuous measure of individual transmissible risk be useful in clinical assessment of substance use disorder? Findings from the National Epidemiological Survey on Alcohol and Related Conditions
    Ty A Ridenour
    Center for Education and Drug Abuse Research, University of Pittsburgh, USA
    Drug Alcohol Depend 119:10-7. 2011
    ....
  37. ncbi request reprint Neurobehavior disinhibition in childhood predisposes boys to substance use disorder by young adulthood: direct and mediated etiologic pathways
    Ralph E Tarter
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Drug Alcohol Depend 73:121-32. 2004
    ..Evaluations were conducted to determine the context in which neurobehavior disinhibition in relation to parental SUD, parental neglect of the child and child's social maladjustment culminated in a DSM-III-R diagnosis of SUD...
  38. pmc Husbands' SUD is associated with higher levels of co-occurring but not non-co-occurring psychiatric disorders among their wives
    Jack R Cornelius
    Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Addict Behav 33:1231-4. 2008
    ..We hypothesized that the presence of SUDs among males would be associated with a higher level of SUDs, of co-occurring psychiatric disorders, and of non-co-occurring psychiatric disorders in their wives...
  39. ncbi request reprint Association among parental substance use disorder, p300 amplitude, and neurobehavioral disinhibition in preteen boys at high risk for substance use disorder
    Miguel E Habeych
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 16261, USA
    Psychol Addict Behav 19:123-30. 2005
    ..It was concluded that the P300 amplitude does not mediate the association between parental SUD and child's neurobehavioral disinhibition...
  40. pmc Premature mortality among males with substance use disorders
    Jack R Cornelius
    Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 33:156-60. 2008
    ..The objective of this study was to assess whether the presence of SUD or ASP is associated with early mortality among males (fathers) in a predominantly community sample, using a 15-year prospective longitudinal study design...
  41. ncbi request reprint An application of item response theory to the DSM-III-R criteria for borderline personality disorder
    Ulrike Feske
    Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA
    J Pers Disord 21:418-33. 2007
    ..The general conclusion is that the criteria do represent a coherent syndrome and that further research on the informational value of the individual criteria would be useful...
  42. ncbi request reprint Early age of first sexual intercourse and affiliation with deviant peers predict development of SUD: a prospective longitudinal study
    Jack R Cornelius
    Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 32:850-4. 2007
    ..The objective of this study was to assess whether early onset of sexual intercourse and affiliation with deviant peers serve as predictors of the development of SUD, using a prospective longitudinal study design...
  43. ncbi request reprint Assessment of risk for substance use disorder consequent to consumption of illegal drugs: psychometric validation of the neurobehavior disinhibition trait
    Ada C Mezzich
    Center for Education and Drug Abuse Research CEDAR, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261, USA
    Psychol Addict Behav 21:508-15. 2007
    ..The ND trait may be useful for detecting youths at high risk for developing SUD and related outcomes...
  44. ncbi request reprint Direct and mediated associations between P300 amplitude in childhood and substance use disorders outcome in young adulthood
    Miguel E Habeych
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Biol Psychiatry 57:76-82. 2005
    ..This investigation had two aims: 1) determine whether P300 amplitude in late childhood is a predictor of SUD outcome by age 19; and 2) evaluate whether neurobehavior disinhibition (ND) mediates this association...
  45. ncbi request reprint Dental abnormalities in children of fathers with substance use disorders
    Jack R Cornelius
    School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Addict Behav 29:979-82. 2004
    ..The data from this study provide evidence that paternal SUDs (HAR vs. LAR status) is associated with poor dental condition, poor oral hygiene, a greater need for dental treatment, and inadequate levels of dental treatment utilization...
  46. ncbi request reprint The MAOA promoter polymorphism, disruptive behavior disorders, and early onset substance use disorder: gene-environment interaction
    Michael M Vanyukov
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Psychiatr Genet 17:323-32. 2007
    ....
  47. ncbi request reprint Liability to substance use disorders: 1. Common mechanisms and manifestations
    Michael M Vanyukov
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
    Neurosci Biobehav Rev 27:507-15. 2003
    ..An accompanying paper describes an approach to the quantitative estimation of this trait...
  48. ncbi request reprint Efficacy of valproate maintenance in patients with bipolar disorder and alcoholism: a double-blind placebo-controlled study
    Ihsan M Salloum
    Western Psychiatric Institute and Clinic of the University of Pittsburgh Medical Center and School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Arch Gen Psychiatry 62:37-45. 2005
    ..Patients with comorbid substance abuse disorders often are excluded from clinical trials. Thus, treatments targeting this high-risk clinical population are lacking...
  49. pmc PTSD contributes to teen and young adult cannabis use disorders
    Jack R Cornelius
    Center for Education and Drug Abuse Research, University of Pittsburgh, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 35:91-4. 2010
    ..This study addresses the effect of PTSD on CUD among teenagers transitioning to young adulthood...
  50. ncbi request reprint Child neglect and oral health problems in offspring of substance-abusing fathers
    Ada C Mezzich
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Addict 16:397-402. 2007
    ....
  51. ncbi request reprint Childhood risk categories for adolescent substance involvement: a general liability typology
    Duncan B Clark
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 77:13-21. 2005
    ..The findings indicate that these five risk categories constitute general liability classes for adolescent substance involvement, and may identify homogeneous groups of children requiring distinct preventive interventions...
  52. ncbi request reprint Origins and consequences of child neglect in substance abuse families
    Marija G Dunn
    School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Clin Psychol Rev 22:1063-90. 2002
    ....
  53. ncbi request reprint Modeling the pathways linking childhood hyperactivity and substance use disorder in young adulthood
    Ralph E Tarter
    Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Psychol Addict Behav 21:266-71. 2007
    ..These results indicate that hyperactivity is a diathesis for both internalizing and externalizing disturbances that, in turn, portend differential expression of psychosocial maladjustment presaging SUD...
  54. pmc Modeling the association between sexual maturation, transmissible risk, and peer relationships during childhood and adolescence on development of substance use disorder in young adulthood
    Michelle S Horner
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Am J Addict 22:474-80. 2013
    ..This prospective study investigated pubertal timing and transmissible risk in relation to affiliation with deviant peers on the development of substance use disorder (SUD)...
  55. ncbi request reprint Divalproex utility in bipolar disorder with co-occurring cocaine dependence: a pilot study
    Ihsan M Salloum
    Western Psychiatric Institute and Clinic of the University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Addict Behav 32:410-5. 2007
    ..The aim of this open-label pilot study was to evaluate the utility of divalproex in decreasing cocaine use and stabilizing mood symptoms among patients with bipolar disorder with comorbid cocaine dependence...
  56. ncbi request reprint Social dominance mediates the association of testosterone and neurobehavioral disinhibition with risk for substance use disorder
    Ralph E Tarter
    Department of Pharmaceutical Sciences, University of Pittsburgh, PA 15261, USA
    Psychol Addict Behav 21:462-8. 2007
    ..In addition, SD/NVB mediated the association between ND and SUD. These findings suggest that development of SUD is influenced by androgen-dependent and neurobehavioral processes via a social motivational style characterized by SD/NVB...
  57. ncbi request reprint Characteristics of men with substance use disorder consequent to illicit drug use: comparison of a random sample and volunteers
    Maureen D Reynolds
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Drug Alcohol Depend 75:241-51. 2004
    ..It was hypothesized that volunteers would be more self-disclosing and exhibit more severe disturbances compared to randomly recruited subjects...
  58. ncbi request reprint Resource use in decompensated heart failure by disease progression categories
    Sandra L Kane-Gill
    Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, PA 15261, USA
    Congest Heart Fail 13:22-8. 2007
    ..05): echocardiography, electrophysiology, neurodiagnostic, nuclear cardiology, and pharmacy. Careful analysis of hospital resource use by services for heart failure patients provides opportunities for institutional cost containment...
  59. ncbi request reprint Concurrent alcohol and cocaine dependence impact on physical health among psychiatric patients
    Ihsan M Salloum
    Addiction Medicine Services, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    J Addict Dis 23:71-81. 2004
    ..The results indicated that the concomitant alcohol and cocaine dependence group had higher rates of multiple physical disorders and also of multiple hepatitis infections than either the alcohol-only or the cocaine-only groups...
  60. pmc Does stress mediate the development of substance use disorders among youth transitioning to young adulthood?
    Jack Cornelius
    Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Drug Alcohol Abuse 40:225-9. 2014
    ..However, it remains unclear whether life stress mediates the relationship between TLI and SUD, or whether stress predicts SUD...
  61. doi request reprint Psychological dysregulation during adolescence mediates the association of parent-child attachment in childhood and substance use disorder in adulthood
    Zu Wei Zhai
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA
    Am J Drug Alcohol Abuse 40:67-74. 2014
    ....
  62. ncbi request reprint Impact of concurrent alcohol misuse on symptom presentation of acute mania at initial evaluation
    Ihsan M Salloum
    Center for Psychiatric and Chemical Dependency Services, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15213, USA
    Bipolar Disord 4:418-21. 2002
    ..The aim of this study was to evaluate the impact of current alcohol misuse on symptom presentation of acute mania...
  63. ncbi request reprint Item response theory analysis of diagnostic criteria for alcohol and cannabis use disorders in adolescents: implications for DSM-V
    Christopher S Martin
    Western Psychiatric Institute and Clinic, Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Abnorm Psychol 115:807-14. 2006
    ..The development process for the fifth edition (DSM-V) should be informed by statistical models such as those used in this study...
  64. pmc Analysis of risk factors for adverse drug events in critically ill patients*
    Sandra L Kane-Gill
    Department of Pharmacy and Clinical Translational Sciences, University of Pittsburgh, School of Pharmacy, Center for Pharmacoinformatics and Outcomes Research, Pittsburgh, PA, USA
    Crit Care Med 40:823-8. 2012
    ..An evaluation of risk factors for adverse drug events in critically ill patients has not been previously studied. The purpose of this original study was to determine risk factors for adverse drug events in critically ill adult patients...
  65. ncbi request reprint Comparing intravenous amiodarone or lidocaine, or both, outcomes for inpatients with pulseless ventricular arrhythmias
    Rhonda S Rea
    University of Pittsburgh School of Pharmacy, Center for Pharmacoinformatics and Outcomes Research, Department of Pharmaceutical Sciences, PA, and Saint Mary s Hospital Mayo Foundation, Rochester, MN, USA
    Crit Care Med 34:1617-23. 2006
    ..To compare survival rates of patients with in-hospital cardiac arrest due to pulseless ventricular tachycardia/ventricular fibrillation treated with lidocaine, amiodarone, or amiodarone plus lidocaine...
  66. doi request reprint Examination of how a survey can spur culture changes using a quality improvement approach: a region-wide approach to determining a patient safety culture
    Janice Pringle
    School of Pharmacy, University of Pittsburgh, Pennsylvania 15203, USA
    Am J Med Qual 24:374-84. 2009
    ..Due to the complex nature of safety culture within health care systems, determining how these surveys can be used will require further investigation...
  67. ncbi request reprint Outcomes and costs of abciximab versus eptifibatide for percutaneous coronary intervention
    James C Coons
    Cardiology Specialty Resident, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Ann Pharmacother 39:1621-6. 2005
    ..However, drug selection is often based on clinicians' preference and cost because few studies have directly compared abciximab and eptifibatide...
  68. ncbi request reprint Substance abuse and associated psychosocial risk factors among Turkish male adolescents
    Sema Aytaclar
    Bakirkoy State Hospital for Psychiatric and Neurological Diseases, Istanbul, Turkey
    Addict Behav 28:1419-29. 2003
    ..These findings indicate that the Turkish version of the DUSI is an efficient method for multidimensional screening of youth who need treatment for substance abuse...
  69. ncbi request reprint An application of item response theory analysis to alcohol, cannabis, and cocaine criteria in DSM-IV
    James W Langenbucher
    Center of Alcohol Studies, Rutgers University, Piscataway, NJ 08854 8001, USA
    J Abnorm Psychol 113:72-80. 2004
    ..IRT can be used to study the construct validity of DSM-IV diagnoses and to identify diagnostic criteria with poor performance...
  70. ncbi request reprint Are the Naranjo criteria reliable and valid for determination of adverse drug reactions in the intensive care unit?
    Sandra L Kane-Gill
    Ohio State University, Columbus, OH, USA
    Ann Pharmacother 39:1823-7. 2005
    ..The Naranjo criteria are frequently used for determination of causality for suspected adverse drug reactions (ADRs); however, the psychometric properties have not been studied in the critically ill...
  71. ncbi request reprint Substance abuse amplifies the risk for violence in schizophrenia spectrum disorder
    Murat Erkiran
    Bakirkoy State Hospital for Psychiatric and Neurological Diseases, Istanbul, Turkey
    Addict Behav 31:1797-805. 2006
    ..Based on the results of this study, it is feasible to identify individual with schizophrenic spectrum disorder who are at high risk for violence...

Research Grants3

  1. Quantifying and Tracking Risk for Substance Use Disorder
    Levent Kirisci; Fiscal Year: 2007
    ..The long-term career goal will thus be to apply my psychometric and statistical expertise to develop instrumentation that clarifies SUD etiology and conjointly has practical utility. ..