Yuriy Kirichok

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Rediscovering sperm ion channels with the patch-clamp technique
    Yuriy Kirichok
    Department of Physiology, University of California San Francisco UCSF Mail Code 2140, Genentech Hall Room N272F 600 16th Street, San Francisco, CA 94158, USA
    Mol Hum Reprod 17:478-99. 2011
  2. doi request reprint Progesterone activates the principal Ca2+ channel of human sperm
    Polina V Lishko
    Department of Physiology, University of California San Francisco, UCSF Mail Code 2140, Genentech Hall Room N272F, 600 16th Street, San Francisco, California 94158, USA
    Nature 471:387-91. 2011
  3. pmc Disruption of the principal, progesterone-activated sperm Ca2+ channel in a CatSper2-deficient infertile patient
    James F Smith
    Department of Urology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 110:6823-8. 2013
  4. pmc The role of Hv1 and CatSper channels in sperm activation
    Polina V Lishko
    Department of Physiology, University of California San Francisco, San Francisco, CA 94158, USA
    J Physiol 588:4667-72. 2010
  5. pmc Mechanism of Fatty-Acid-Dependent UCP1 Uncoupling in Brown Fat Mitochondria
    Andriy Fedorenko
    Department of Physiology, University of California San Francisco, UCSF Mail Code 2140, Genentech Hall Room N272F, 600 16th Street, San Francisco, CA 94158, USA
    Cell 151:400-13. 2012
  6. doi request reprint Acid extrusion from human spermatozoa is mediated by flagellar voltage-gated proton channel
    Polina V Lishko
    Department of Physiology, University of California, San Francisco, UCSF Mail Code 2140, Genentech Hall, Room N272F, 600 16 th Street, San Francisco, CA 94158, USA
    Cell 140:327-37. 2010
  7. doi request reprint Activity of the mitochondrial calcium uniporter varies greatly between tissues
    Francesca Fieni
    Department of Physiology, University of California, San Francisco, San Francisco, California 94158, USA
    Nat Commun 3:1317. 2012

Collaborators

  • Polina V Lishko
  • Andriy Fedorenko
  • James F Smith
  • Francesca Fieni
  • Inna L Botchkina
  • Catherine Serres
  • Olga Syritsyna
  • Marc Fellous
  • Nadja Mannowetz
  • Sung Bae Lee
  • Yuh Nung Jan

Detail Information

Publications7

  1. pmc Rediscovering sperm ion channels with the patch-clamp technique
    Yuriy Kirichok
    Department of Physiology, University of California San Francisco UCSF Mail Code 2140, Genentech Hall Room N272F 600 16th Street, San Francisco, CA 94158, USA
    Mol Hum Reprod 17:478-99. 2011
    ..This method is critical for identification of the molecular mechanisms that control sperm behavior within the female reproductive tract and make fertilization possible...
  2. doi request reprint Progesterone activates the principal Ca2+ channel of human sperm
    Polina V Lishko
    Department of Physiology, University of California San Francisco, UCSF Mail Code 2140, Genentech Hall Room N272F, 600 16th Street, San Francisco, California 94158, USA
    Nature 471:387-91. 2011
    ....
  3. pmc Disruption of the principal, progesterone-activated sperm Ca2+ channel in a CatSper2-deficient infertile patient
    James F Smith
    Department of Urology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 110:6823-8. 2013
    ....
  4. pmc The role of Hv1 and CatSper channels in sperm activation
    Polina V Lishko
    Department of Physiology, University of California San Francisco, San Francisco, CA 94158, USA
    J Physiol 588:4667-72. 2010
    ..Here, we discuss how Hv1 and CatSper channels regulate human sperm physiology and the differences in control of sperm intracellular pH and Ca²(+) between species...
  5. pmc Mechanism of Fatty-Acid-Dependent UCP1 Uncoupling in Brown Fat Mitochondria
    Andriy Fedorenko
    Department of Physiology, University of California San Francisco, UCSF Mail Code 2140, Genentech Hall Room N272F, 600 16th Street, San Francisco, CA 94158, USA
    Cell 151:400-13. 2012
    ..A similar LCFA-dependent mechanism of transmembrane H(+) transport may be employed by other SLC25 members and be responsible for mitochondrial uncoupling and regulation of metabolic efficiency in various tissues...
  6. doi request reprint Acid extrusion from human spermatozoa is mediated by flagellar voltage-gated proton channel
    Polina V Lishko
    Department of Physiology, University of California, San Francisco, UCSF Mail Code 2140, Genentech Hall, Room N272F, 600 16 th Street, San Francisco, CA 94158, USA
    Cell 140:327-37. 2010
    ..The importance of Hv1 for sperm activation makes it an attractive target for controlling male fertility...
  7. doi request reprint Activity of the mitochondrial calcium uniporter varies greatly between tissues
    Francesca Fieni
    Department of Physiology, University of California, San Francisco, San Francisco, California 94158, USA
    Nat Commun 3:1317. 2012
    ..Simultaneously, low mitochondrial calcium uniporter activity may also prevent mitochondrial Ca(2+) overload in such active tissues exposed to frequent cytosolic Ca(2+) activity...