Richard A King

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus
    Robert R Graham
    Department of Medicine, Division of Rheumatic and Autoimmune Diseases, University of Minnesota Medical School, Minneapolis, MN, 55455, USA
    Am J Hum Genet 71:543-53. 2002
  2. pmc MC1R mutations modify the classic phenotype of oculocutaneous albinism type 2 (OCA2)
    Richard A King
    Department of Genetics, University of Minnesota, Minneapolis, MN, 55455, USA
    Am J Hum Genet 73:638-45. 2003
  3. ncbi Tyrosinase gene mutations in oculocutaneous albinism 1 (OCA1): definition of the phenotype
    Richard A King
    Department of Medicine, University of Minnesota, Minneapolis, Minn 55455, USA
    Hum Genet 113:502-13. 2003
  4. ncbi P gene mutations associated with oculocutaneous albinism type II (OCA2)
    William S Oetting
    Department of Medicine, Institute of Human Genetics, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Hum Mutat 25:323. 2005
  5. ncbi The R402Q tyrosinase variant does not cause autosomal recessive ocular albinism
    William S Oetting
    Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Am J Med Genet A 149:466-9. 2009
  6. ncbi A genome-wide search for quantitative trait loci contributing to variation in seasonal pollen reactivity
    Malcolm N Blumenthal
    Department of Medicine, University of Minnesota, Minneapolis, MN, USA
    J Allergy Clin Immunol 117:79-85. 2006
  7. ncbi Correlation of grating acuity with letter recognition acuity in children with albinism
    Curtis R Louwagie
    Medical School, University of Minnesota, Minneapolis, Minnesota 55455 0501, USA
    J AAPOS 10:168-72. 2006
  8. ncbi Oculocutaneous albinism type 1: the last 100 years
    William S Oetting
    Department of Medicine, University of Minnesota, Minneapolis, MN, USA
    Pigment Cell Res 16:307-11. 2003
  9. doi Change in visual acuity in albinism in the early school years
    Johanna M Dijkstal
    Department of Ophthalmology, University of Minnesota, Mayo Mail Code 493, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    J Pediatr Ophthalmol Strabismus 49:81-6; quiz 87. 2012
  10. ncbi CD14 promoter polymorphisms in atopic families: implications for modulated allergen-specific immunoglobulin E and G1 responses
    Duaine R Jackola
    The Asthma and Allergy Program, Division of Pulmonary, Allergy and Critical Care Medicine, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Int Arch Allergy Immunol 139:217-24. 2006

Collaborators

Detail Information

Publications25

  1. pmc Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus
    Robert R Graham
    Department of Medicine, Division of Rheumatic and Autoimmune Diseases, University of Minnesota Medical School, Minneapolis, MN, 55455, USA
    Am J Hum Genet 71:543-53. 2002
    ..We conclude that HLA class II haplotypes containing DRB1 and DQB1 alleles are strong risk factors for human SLE...
  2. pmc MC1R mutations modify the classic phenotype of oculocutaneous albinism type 2 (OCA2)
    Richard A King
    Department of Genetics, University of Minnesota, Minneapolis, MN, 55455, USA
    Am J Hum Genet 73:638-45. 2003
    ..This is the first demonstration of a gene modifying the OCA phenotype in humans...
  3. ncbi Tyrosinase gene mutations in oculocutaneous albinism 1 (OCA1): definition of the phenotype
    Richard A King
    Department of Medicine, University of Minnesota, Minneapolis, Minn 55455, USA
    Hum Genet 113:502-13. 2003
    ....
  4. ncbi P gene mutations associated with oculocutaneous albinism type II (OCA2)
    William S Oetting
    Department of Medicine, Institute of Human Genetics, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Hum Mutat 25:323. 2005
    ..This information will also help define the critical functional domains of the P protein. Mutations associated with OCA2 can be found in the Albinism Database (http://albinismdb.med.umn.edu)...
  5. ncbi The R402Q tyrosinase variant does not cause autosomal recessive ocular albinism
    William S Oetting
    Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Am J Med Genet A 149:466-9. 2009
    ..We conclude that the codon 402 variant of the tyrosinase gene is not associated with albinism...
  6. ncbi A genome-wide search for quantitative trait loci contributing to variation in seasonal pollen reactivity
    Malcolm N Blumenthal
    Department of Medicine, University of Minnesota, Minneapolis, MN, USA
    J Allergy Clin Immunol 117:79-85. 2006
    ..Asthma and atopy represent complex traits for which genetic predisposition has been demonstrated. Pollen sensitivity, whether seasonal or chronic, appears to be a major contributor to the asthmatic phenotype...
  7. ncbi Correlation of grating acuity with letter recognition acuity in children with albinism
    Curtis R Louwagie
    Medical School, University of Minnesota, Minneapolis, Minnesota 55455 0501, USA
    J AAPOS 10:168-72. 2006
    ..This study was undertaken to determine whether grating acuity in early childhood can be used as a predictor of letter recognition acuity in patients with albinism...
  8. ncbi Oculocutaneous albinism type 1: the last 100 years
    William S Oetting
    Department of Medicine, University of Minnesota, Minneapolis, MN, USA
    Pigment Cell Res 16:307-11. 2003
    ..Though much of the research in albinism has involved OCA1, there are many unanswered questions about OCA1 and albinism, in general. The next 100 yr should still provide many surprises as did the first 100 yr...
  9. doi Change in visual acuity in albinism in the early school years
    Johanna M Dijkstal
    Department of Ophthalmology, University of Minnesota, Mayo Mail Code 493, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    J Pediatr Ophthalmol Strabismus 49:81-6; quiz 87. 2012
    ..To determine whether binocular best-corrected visual acuity (B-BCVA) improves in the early school years in patients with albinism and whether this is related to type of albinism, ocular pigment, or appearance of the macula...
  10. ncbi CD14 promoter polymorphisms in atopic families: implications for modulated allergen-specific immunoglobulin E and G1 responses
    Duaine R Jackola
    The Asthma and Allergy Program, Division of Pulmonary, Allergy and Critical Care Medicine, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Int Arch Allergy Immunol 139:217-24. 2006
    ..We sought to determine if a single nucleotide polymorphism in the CD14 promoter region is associated with atopy in atopic families, and to assess its influence on serum levels of CD14 and allergen-specific IgE and IgG1 responses...
  11. ncbi Efficacy of spectacles in persons with albinism
    Jill Anderson
    Department of Ophthalmology, University of Minnesota, Minneapolis, USA
    J AAPOS 8:515-20. 2004
    ..We sought to evaluate the effect of spectacle correction of refractive error on clinical findings and recorded compliance with refractive corrections, as little detailed data exist...
  12. ncbi Identification and characterization of a DNase hypersensitive region of the human tyrosinase gene
    James P Fryer
    Department of Medicine and Institute of Human Genetics, University of Minnesota, Minneapolis, MN 55455, USA
    Pigment Cell Res 16:679-84. 2003
    ..We believe that this region of homology contains sequences critical in the regulation of the human tyrosinase gene and is a candidate for the location of OCA1 mutations...
  13. ncbi The White platelet syndrome: a new autosomal dominant platelet disorder
    James G White
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA
    Platelets 15:173-84. 2004
    ..However, gray platelets were not present among their circulating cells. The WPS is a unique autosomal dominant condition that can be classified among the platelet granule deficiency disorders...
  14. ncbi A 'touch' of the White platelet syndrome
    James G White
    Department of Laboratory Medicine, University of Minnesota, Minneapolis, MN 55455, USA
    Platelets 16:346-61. 2005
    ..Genetic studies to determine if this is the case are currently in progress...
  15. ncbi X-linked high myopia associated with cone dysfunction
    Terri L Young
    Department of Ophthalmology, University of Minnesota Medical School, Minneapolis, USA
    Arch Ophthalmol 122:897-908. 2004
    ..We studied a second family from Minnesota with a similar X-linked phenotype, also of Danish descent. All affected males had protanopia instead of deuteranopia...
  16. ncbi Positive angle kappa in albinism
    Kimberly S Merrill
    Department of Ophthalmology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J AAPOS 8:237-9. 2004
    ..There is a high prevalence of strabismus in patients with albinism. We investigated the prevalence of a positive angle kappa in patients with albinism and report its effect on assessment of binocular alignment...
  17. ncbi The prevalence of attention-deficit/hyperactivity disorder among persons with albinism
    Beth Kutzbach
    Department of Pediatrics, University of Minnesota, Minneapolis 55455, USA
    J Child Neurol 22:1342-7. 2007
    ..The prevalence of ADHD among children and adults with albinism is more frequent than that reported among the general population and is not related to binocular best-corrected visual acuity...
  18. ncbi A genome-wide search for allergic response (atopy) genes in three ethnic groups: Collaborative Study on the Genetics of Asthma
    Malcolm N Blumenthal
    Department of Medicine, University of Minnesota, MMC 434 Mayo, 420 Delaware SE, Minneapolis, MN 55455, USA
    Hum Genet 114:157-64. 2004
    ..65), 8p (D8S1113, lod=1.60), 12p (D12S372, lod=1.54) and 14q (D14S749, lod=1.70). These results suggest that several regions may harbor genes contributing to the risk for atopy and these may interact with one another in a complex manner...
  19. ncbi Spectrum of foveal development in albinism detected with optical coherence tomography
    Patti S Harvey
    Department of Ophthalmology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J AAPOS 10:237-42. 2006
    ..Methods: Eleven patients with albinism and BCVA > or = 20/60 were recruited for OCT. Average central macular thickness was recorded. Presence of an oval annular reflex was determined with binocular indirect ophthalmoscopy...
  20. ncbi Grating acuity in albinism in the first three years of life
    Sarah J Whang
    Departments of Ophthalmology Pediatrics Medicine, and the Institute of Human Genetics, University of Minnesota, Minneapolis, Minnesota, USA
    J AAPOS 6:393-6. 2002
    ..To compare grating acuity of children 1 to 3 years old with albinism with that of age-matched normal children, and to determine whether ocular pigment and macular structure are predictive of grating visual acuity...
  21. ncbi Functional genomics tools for the analysis of zebrafish pigment
    Michael A Pickart
    Department of Oral Sciences and Minnesota Craniofacial Research Training Program MinnCResT, University of Minnesota, Minneapolis, MN, USA
    Pigment Cell Res 17:461-70. 2004
    ....
  22. ncbi Gene expression profiling in murine obliterative airway disease
    Jeffrey D Lande
    Department of Medicine, University of Minnesota Medical School, Minneapolis, USA
    Am J Transplant 5:2170-84. 2005
    ..These observations confirm and expand the list of genes and molecular processes that can be studied as potential surrogate markers or targets for intervention of OB...
  23. ncbi New locus for autosomal dominant high myopia maps to the long arm of chromosome 17
    Prasuna Paluru
    Division of Ophthalmology, Children s Hospital of Philadelphia and The University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Invest Ophthalmol Vis Sci 44:1830-6. 2003
    ..To map the gene(s) associated with autosomal dominant (AD) high-grade myopia...
  24. pmc A 122.5-kilobase deletion of the P gene underlies the high prevalence of oculocutaneous albinism type 2 in the Navajo population
    Zanhua Yi
    Department of Pediatrics, College of Medicine, University of Arizona, Tucson, AZ 85724, USA
    Am J Hum Genet 72:62-72. 2003
    ..5%. The estimated prevalence of OCA2 in Navajos is between approximately 1 per 1,500 and 1 per 2,000. We further estimate that this mutation originated 400-1,000 years ago from a single founder...
  25. ncbi Positive angle kappa in albinism
    C Gail Summers
    Am J Ophthalmol 138:1093. 2004