Research Topics
| Jean KingSummaryAffiliation: University of Massachusetts Medical School Country: USA Publications
Research Grants
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Detail Information
Publications
Sequence and seasonal effects of salivary cortisolJ A King
Behavioral Neuroscience Program of the Department of Psychiatry, University of Massachusetts Medical School, USA
Behav Med 26:67-73. 2000..The findings in this study suggest that repeated saliva sampling and seasonal variation in cortisol levels may independently affect adrenal response and, therefore, need to be accounted for in longitudinal studies...- Association of stress, hostility and plasma testosterone levelsJean A King
Department of Psychiatry, University of Massachusetts Medical School, North Worcester, MA 01655, USA
Neuro Endocrinol Lett 26:355-60. 2005.... 
Procedure for minimizing stress for fMRI studies in conscious ratsJean A King
Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical Center, Worcester, MA 01655, USA
J Neurosci Methods 148:154-60. 2005..The feasibility of improving the quality of fMRI data acquired in alert rats by utilizing a relatively simple technique is presented...- Deficits in testosterone facilitate enhanced fear responseJean A King
Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01655, USA
Psychoneuroendocrinology 30:333-40. 2005..These studies suggest that testosterone decline may have a significant effect on increasing innate fear response and fear-induced enhancement of analgesia in male rats... - Neural substrates underlying impulsivityJean A King
Department of Psychiatry, Center for Comparative NeuroImaging, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Ann N Y Acad Sci 1008:160-9. 2003..As noninvasive brain imaging, neurochemical, and behavioral approaches are combined, our knowledge of the neural networks underlying impulsivity will hopefully give rise to therapeutic approaches aimed at alleviating this disorder... - Early sexual abuse and low cortisolJ A King
Department of Psychiatry, University of Massachusetts Medical School, Worcester 01655, USA
Psychiatry Clin Neurosci 55:71-4. 2001..The data suggest that children may have an impaired HPA axis after early trauma... - Seed finding in golden hamsters: a potential animal model for screening anxiolytic drugsJean A King
Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01655, USA
Neuropsychobiology 45:150-5. 2002..These data provide evidence that seed finding in hamsters may serve as an animal model for screening potential anxiolytic drugs... - Imaging the neural substrates involved in the genesis of pentylenetetrazol-induced seizuresMathew E Brevard
Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. mathew.brevard.umassmed.edu
Epilepsia 47:745-54. 2006..Neurons in these areas may contribute to the neural network controlling the initiation of generalized tonic-clonic seizure... - Anticorrelated resting-state functional connectivity in awake rat brainZhifeng Liang
Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01655, USA
Neuroimage 59:1190-9. 2012..In addition, combining the neurobiological data of the IL-amygdala circuit in rodents, the finding of the present study will enable further investigation of the neurobiological basis underlying anticorrelation... - Stress, social support, and cortisol: inverse associations?Milagros C Rosal
University of Massachusetts Medical School, Division of Preventive and Behavioral Medicine, Department of Medicine, Worcester, 01655, USA
Behav Med 30:11-21. 2004..Both findings deserve further investigation... 
The role of 5-HT1A receptors in the behavioral responses associated with innate fearJessica Shields
University of Massachusetts Medical School, Department of Psychiatry, Center for Comparative NeuroImaging, 55 Lake Avenue North, Worcester, MA 01655, USA
Behav Neurosci 122:611-7. 2008..Taken together, these results suggest an additional anxyolitic-like effect of 8-OHDPAT in innate fear paradigms...- Intrinsic organization of the anesthetized brainZhifeng Liang
Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
J Neurosci 32:10183-91. 2012..With the unique spatial and temporal scales of resting-state fMRI, this study has opened a new avenue for understanding the neural mechanism of (un)consciousness... - A comparison of brain and behavioral effects of varenicline and nicotine in ratsJean King
Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, MA 01655, USA
Behav Brain Res 223:42-7. 2011..This study points to different effects of varenicline and nicotine on neuronal and behavioral indices... - Uncovering intrinsic connectional architecture of functional networks in awake rat brainZhifeng Liang
Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
J Neurosci 31:3776-83. 2011.... - Female fear: influence of estrus cycle on behavioral response and neuronal activationWei Chen
Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01605, USA
Behav Brain Res 201:8-13. 2009..Taken together, these results suggest that the female's hormonal status may be correlated with alterations in both neuronal and behavioral indices of fear... - Activation of neural pathways associated with sexual arousal in non-human primatesCraig F Ferris
Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
J Magn Reson Imaging 19:168-75. 2004..To evaluate brain activity associated with sexual arousal, fully conscious male marmoset monkeys were imaged during presentation of odors that naturally elicit high levels of sexual activity and sexual motivation... - fMRI of generalized absence status epilepticus in conscious marmoset monkeys reveals corticothalamic activationJeffrey R Tenney
Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, USA
Epilepsia 45:1240-7. 2004..A nonhuman primate model of generalized absence status epilepticus was developed for use in functional magnetic resonance imaging (fMRI) experiments to elucidate the brain mechanisms underlying this disorder... - FMRI of brain activation in a genetic rat model of absence seizuresJeffrey R Tenney
Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Epilepsia 45:576-82. 2004..EEG-triggered functional magnetic resonance imaging (fMRI) was used to identify areas of brain activation during spontaneous spike-and-wave discharges (SWDs) in an epileptic rat strain under awake conditions... - Corticothalamic modulation during absence seizures in rats: a functional MRI assessmentJeffrey R Tenney
Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School Worcester, Massachusetts 01655, USA
Epilepsia 44:1133-40. 2003..Functional magnetic resonance imaging (fMRI) was used to identify areas of brain activation during absence seizures in an awake animal model... - Imaging brain activation in nicotine-sensitized ratsZhixin Li
Department of Psychiatry, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Brain Res 1199:91-9. 2008.... - Imaging unconditioned fear response with manganese-enhanced MRI (MEMRI)Wei Chen
University of Massachusetts Medical School, Department of Psychiatry, Center for Comparative NeuroImaging, 55 Lake Avenue North, Worcester, MA 01655, USA
Neuroimage 37:221-9. 2007..Therefore the current study support the validity of MEMRI in the exploration of highly relevant complex neural circuitries associated with cognition and emotion... - Regional cerebral blood flow and BOLD responses in conscious and anesthetized rats under basal and hypercapnic conditions: implications for functional MRI studiesKenneth Sicard
Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, U.S.A
J Cereb Blood Flow Metab 23:472-81. 2003..This study also shows that perfusion and perfusion-based functional MRI can be performed in awake animals... - A potential role for adjunctive vitamin D therapy in the management of weight gain and metabolic side effects of second-generation antipsychoticsBenjamin U Nwosu
Division of Pediatric Endocrinology, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
J Pediatr Endocrinol Metab 24:619-26. 2011..Effective strategies to curb these side effects will improve the overall health of youths with psychiatric illnesses who receive SGAs. Herein we present a pilot study on the use of vitamin D in patients on treatment with SGAs... - Mapping resting-state brain networks in conscious animalsNanyin Zhang
Center for Comparative NeuroImaging CCNI, Department of Psychiatry, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, United States
J Neurosci Methods 189:186-96. 2010.... - Confounding effects of volatile anesthesia on CBV assessment in rodent forebrain following ethanol challengeFeng Luo
Experimental Imaging Abbott Laboratories, Abbott Park, Illinois 60064, USA
J Magn Reson Imaging 26:557-63. 2007..To compare and contrast the pattern and characteristics of the cerebral blood volume (CBV) response to ethanol (EtOH) in rats under awake and anesthetized conditions...
Research Grants
- Roots of Mental Illness in ChildrenJean King; Fiscal Year: 2002..Conference program has been organized by a committee consisting of Drs. Jean King and Craig Ferris (both of University of Massachusetts Medical School), in consultation with a steering committee ..
- Possible Significance of Cholinergic Influence in ADHDJean A King; Fiscal Year: 2010..Since ADD is a lifelong challenge these results can be potentially of use to many individuals and families. ..
- Imaging Nicotine-induced behavioral sensitization with fMRIJean King; Fiscal Year: 2009..The imaging of sensitization may provide a powerful new tool for the exploration of novel pharmacologic approaches to treating nicotine addiction, which is the largest contributor to preventable mortality in the developed world. ..
- Imaging Nicotine-induced behavioral sensitization with fMRIJean King; Fiscal Year: 2007..The imaging of sensitization may provide a powerful new tool for the exploration of novel pharmacologic approaches to treating nicotine addiction, which is the largest contributor to preventable mortality in the developed world. ..
- Imaging Unconditioned FearJean King; Fiscal Year: 2006..Since fear experience by all animals, these studies may expand our understanding of anxiety and phobias in general. ..
- NMR Imaging of Prostate Cancer Using LigandsJean King; Fiscal Year: 2005..abstract_text> ..
- Imaging Unconditioned FearJean King; Fiscal Year: 2003..Since fear experience by all animals, these studies may expand our understanding of anxiety and phobias in general. ..
- Imaging Nicotine-induced behavioral sensitization with fMRIJean A King; Fiscal Year: 2010..The imaging of sensitization may provide a powerful new tool for the exploration of novel pharmacologic approaches to treating nicotine addiction, which is the largest contributor to preventable mortality in the developed world. ..