Research Topics
Genomes and GenesSpecies | Kirst King-JonesSummaryAffiliation: University of Utah Country: USA Publications
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Detail Information
Publications
The ecdysone-induced DHR4 orphan nuclear receptor coordinates growth and maturation in DrosophilaKirst King-Jones
Howard Hughes Medical Institute, Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA
Cell 121:773-84. 2005..We propose that DHR4 coordinates growth and maturation in Drosophila by mediating endocrine responses to the attainment of critical weight during larval development...
Nuclear receptors--a perspective from DrosophilaKirst King-Jones
Howard Hughes Medical Institute, Department of Human Genetics, University of Utah School of Medicine, 15 North 2030 East, Room 5100, Salt Lake City, Utah 84112 5331, USA
Nat Rev Genet 6:311-23. 2005..Here, we review recent breakthroughs in our understanding of D. melanogaster nuclear receptors, and interpret these results in light of findings from their evolutionarily conserved vertebrate homologues...
Developmental biology. Less steroids make bigger fliesKirst King-Jones
Howard Hughes Medical Institute, Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
Science 310:630-1. 2005
The Drosophila DHR96 nuclear receptor binds cholesterol and regulates cholesterol homeostasisMichael A Horner
Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA
Genes Dev 23:2711-6. 2009..These studies define DHR96 as a central regulator of cholesterol homeostasis...
The DHR96 nuclear receptor regulates xenobiotic responses in DrosophilaKirst King-Jones
Howard Hughes Medical Institute, Department of Human Genetics, University of Utah School of Medicine, 15 N 2030 E 5100, Salt Lake City, Utah 84112, USA
Cell Metab 4:37-48. 2006..Metabolic and stress-response genes are also controlled by DHR96, implicating its role in coordinating multiple response pathways. This work establishes a new model system for defining the genetic control of xenobiotic stress responses...
