Suwon Kim

Summary

Affiliation: University of Arizona
Country: USA

Publications

  1. pmc Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer
    Sara A Byron
    Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America
    PLoS ONE 7:e46823. 2012
  2. pmc A dominant mutant allele of the ING4 tumor suppressor found in human cancer cells exacerbates MYC-initiated mouse mammary tumorigenesis
    Suwon Kim
    G W Hooper Research Foundation, University of California, San Francisco, California, USA
    Cancer Res 70:5155-62. 2010
  3. pmc A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer
    Suwon Kim
    The G W Hooper Research Foundation and Department of Microbiology and Immunology, Department of Laboratory Medicine and Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:16251-6. 2004
  4. pmc MET and MYC cooperate in mammary tumorigenesis
    Alana L Welm
    G W Hooper Research Foundation and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 102:4324-9. 2005
  5. pmc Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase
    Dun Yang
    Department of Microbiology and Immunology, G W Hooper Research Foundation, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 107:13836-41. 2010
  6. pmc Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis
    Penny L Berger
    Authors Affiliations Laboratory of Integrin Signaling Laboratory of Translational Imaging and Laboratory of Analytical Pathology and Van Andel Institute Graduate School, Grand Rapids Genetics Graduate Program, Michigan State University, Lansing, Michigan and Tranlational Genomics Research Institute and University of Arizona College of Medicine, Phoenix, Arizona
    Cancer Res 74:3357-68. 2014

Collaborators

Detail Information

Publications6

  1. pmc Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer
    Sara A Byron
    Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America
    PLoS ONE 7:e46823. 2012
    ..Consequently, down-regulation of ING4 leads to activation of NF-κB, contributing to tumor progression and reduced disease-free patient survival in breast cancer...
  2. pmc A dominant mutant allele of the ING4 tumor suppressor found in human cancer cells exacerbates MYC-initiated mouse mammary tumorigenesis
    Suwon Kim
    G W Hooper Research Foundation, University of California, San Francisco, California, USA
    Cancer Res 70:5155-62. 2010
    ..Our results provide direct functional evidence that ING4 could suppress the early stages of breast cancer and that dominant mutant alleles of ING4 might contribute to malignant development...
  3. pmc A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer
    Suwon Kim
    The G W Hooper Research Foundation and Department of Microbiology and Immunology, Department of Laboratory Medicine and Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:16251-6. 2004
    ..Ectopic expression of ING4 attenuated the growth of T47D human breast cancer cells in soft agar. We conclude that ING4 is a strong candidate as a tumor suppressor gene...
  4. pmc MET and MYC cooperate in mammary tumorigenesis
    Alana L Welm
    G W Hooper Research Foundation and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 102:4324-9. 2005
    ..The approach described here should provide a useful model with which to efficiently test effects of various genes on tumor development in the breast...
  5. pmc Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase
    Dun Yang
    Department of Microbiology and Immunology, G W Hooper Research Foundation, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 107:13836-41. 2010
    ....
  6. pmc Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis
    Penny L Berger
    Authors Affiliations Laboratory of Integrin Signaling Laboratory of Translational Imaging and Laboratory of Analytical Pathology and Van Andel Institute Graduate School, Grand Rapids Genetics Graduate Program, Michigan State University, Lansing, Michigan and Tranlational Genomics Research Institute and University of Arizona College of Medicine, Phoenix, Arizona
    Cancer Res 74:3357-68. 2014
    ..The clinical implication is that Pten/ING4 negative and ING4-only negative tumors may reflect two distinct subtypes of prostate cancer...