Research Topics
| Scott Y KimSummaryAffiliation: University of Michigan Country: USA Publications
Research Grants
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Detail Information
Publications
Impaired decision-making ability in subjects with Alzheimer's disease and willingness to participate in researchScott Y H Kim
Department of Psychiatry, University of Rochester School of Medicne and Dentistry, NY 14642, USA
Am J Psychiatry 159:797-802. 2002..The authors examined the effects of cognitive and decisional impairment on willingness to participate in research among persons with Alzheimer's disease...
Sham surgery controls in Parkinson's disease clinical trials: views of participantsScott Y H Kim
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA
Mov Disord 27:1461-5. 2012..We interviewed participants of such trials, specifically examining their understanding and attitudes regarding sham surgery...
Comparison of enrollees and decliners of Parkinson disease sham surgery trialsScott Y H Kim
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
Mov Disord 27:506-11. 2012..Although both are attracted to research because of hopes of personal benefit, this hope is clearly distinguishable from an expectation of benefit and does not imply a failure to understand the main purpose of research...
Effect of public deliberation on attitudes toward surrogate consent for dementia researchS Y H Kim
Center for Bioethics and Social Sciences in Medicine, University of Michigan, Ann Arbor 48109, USA
Neurology 77:2097-104. 2011..To assess the informed, deliberative views of the older general public toward a policy of allowing surrogate consent for Alzheimer disease (AD) research...
Variability of judgments of capacity: experience of capacity evaluators in a study of research consent capacityScott Y H Kim
Center for Bioethics and Social Sciences in Medicine and Dept of Psychiatry, University of Michigan, 300 North Ingalls Street, Ann Arbor, MI 48109, USA
Psychosomatics 52:346-53. 2011..Assessment of decision-making capacity is a common and important function of psychiatric consultants. However, the sources of variability in evaluators' judgments have not been well characterized...
The ethics of informed consent in Alzheimer disease researchScott Y H Kim
Center for Bioethics and Social Sciences in Medicine, University of Michigan, 300 North Ingalls 7C27, Ann Arbor, Michigan 48109, USA
Nat Rev Neurol 7:410-4. 2011....
Assessing the public's views in research ethics controversies: deliberative democracy and bioethics as natural alliesScott Y H Kim
University of Michigan, Ann Arbor, MI 48109, USA
J Empir Res Hum Res Ethics 4:3-16. 2009..The potential pitfalls of DD and the means of minimizing them as well as future research directions are also discussed...
Assessing and communicating the risks and benefits of gene transfer clinical trialsScott Y H Kim
Bioethics Program, University of Michigan Medical School, 300 North Ingalls Street, Ann Arbor, MI 48109 0429, USA
Curr Opin Mol Ther 8:384-9. 2006....
Evidence-based ethics for neurology and psychiatry researchScott Y H Kim
Department of Psychiatry, Bioethics Program, and Program for Improving Health Care Decisions, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
NeuroRx 1:372-7. 2004..For each of these issues, selected empirical data are reviewed, areas for further inquiry are noted, and the need for development of novel methods for bioethics policy research is discussed...
The dilemma of hidden ethical dilemmasScott Y H Kim
Department of Psychiatry, the Bioethics Program, and the Program for Improving Health Care Decisions, University of Michigan Medical School, 300 North Ingalls, 7C27, Ann Arbor, MI 48109, USA
Acad Psychiatry 28:168-9. 2004
Proxy and surrogate consent in geriatric neuropsychiatric research: update and recommendationsScott Y H Kim
Department of Psychiatry and the Program in Clinical Ethics, University of Rochester Medical Center, Rochester, NY, USA
Am J Psychiatry 161:797-806. 2004..The authors provide an updated discussion, critique, and recommendations regarding the need for clear legal and regulatory policy on this issue...
Assessing the quality of democratic deliberation: a case study of public deliberation on the ethics of surrogate consent for researchRaymond de Vries
University of Michigan, Bioethics Program, Ann Arbor, 300 North Ingalls Street, MI 48109 0429, USA
Soc Sci Med 70:1896-903. 2010..We demonstrate that DD can be reliably used to elicit opinions of the public and show how analysis of the quality of deliberations can offer insight into the ways opinions about ethical dilemmas are formed and changed...
Benefits and burdens of placebos in psychiatric researchScott Y H Kim
Department of Psychiatry, University of Rochester School of Medicine and Dentistry, 300 Crittenden Boulevard, Rochester, NY 14642, USA
Psychopharmacology (Berl) 171:13-8. 2003..Current practice permits placebos in such settings, as long as the benefits outweigh the risks and burdens...
Trust in early phase research: therapeutic optimism and protective pessimismScott Y H Kim
Department of Psychiatry, the Bioethics Program, The Center for Behavioral and Decision Sciences in Medicine, University of Michigan, 300 North Ingalls Street, 7C27, Ann Arbor, MI, 48109, USA
Med Health Care Philos 11:393-401. 2008..We discuss this discrepancy using "frameworks of trust" and demonstrate the need to incorporate these frameworks into the existing model of informed consent...
Advance directives and outcomes of surrogate decision making before deathMaria J Silveira
Veterans Affairs Center for Clinical Management Research, and Division of General Medicine, University of Michigan, Ann Arbor, USA
N Engl J Med 362:1211-8. 2010..Recent discussions about health care reform have raised questions regarding the value of advance directives...
Returning individual research results: development of a cancer genetics education and risk communication protocolJ Scott Roberts
Department of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, MI 48109 2029, USA
J Empir Res Hum Res Ethics 5:17-30. 2010....
Determining when impairment constitutes incapacity for informed consent in schizophrenia researchScott Y H Kim
Department of Psychiatry, Bioethics Program, and Center for Behavioral and Decision Sciences in Medicine, University of Michigan, 300 North Ingalls, Ann Arbor, MI 48109 0429, and Massachusetts General Hospital, Boston, USA
Br J Psychiatry 191:38-43. 2007..Although people with schizophrenia display impaired abilities for consent, it is not known how much impairment constitutes incapacity...
The capacity to appoint a proxy and the possibility of concurrent proxy directivesScott Y H Kim
University of Michigan Bioethics Program, Ann Arbor, MI 48109 0429, USA
Behav Sci Law 24:469-78. 2006..We first propose a rationale for assessing the capacity to appoint a proxy and then describe a novel interview instrument for assessing the capacity to appoint a proxy for research consent...
Do clinicians follow a risk-sensitive model of capacity-determination? An experimental video surveyScott Y H Kim
Dept of Psychiatry, the Bioethics Program, and the Center for Behavioral and Decision Sciences in Medicine, Univ of Michigan, MI, USA
Psychosomatics 47:325-9. 2006..Thus, clinicians, in fact, use the normative risk-sensitive model for capacity, but there remains considerable unexplained variability in their judgments...
What do people at risk for Alzheimer disease think about surrogate consent for research?Scott Y H Kim
Department of Psychiatry, Center for Behavioral and Decision Sciences in Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
Neurology 65:1395-401. 2005..Research involving decisionally incapable adults remains an unsettled and controversial policy issue, especially for protocols that involve significant risk to participants. Few data exist to guide policymakers and IRBs..
When does decisional impairment become decisional incompetence? Ethical and methodological issues in capacity research in schizophreniaScott Y H Kim
Department of Psychiatry, University of Michigan, 300 North Ingalls Street, 7C27, Ann Arbor, MI 48109, USA
Schizophr Bull 32:92-7. 2006..Future research needs are outlined...
Science and ethics of sham surgery: a survey of Parkinson disease clinical researchersScott Y H Kim
Department of Psychiatry, Bioethics Program, Center for Behavioral and Decision Sciences in Medicine, University of Michigan, Ann Arbor, 48109, USA
Arch Neurol 62:1357-60. 2005..Sham surgery is used in neurosurgical clinical trials in Parkinson disease (PD) but remains controversial. The controversy may be compounded when gene-transfer technologies are tested in sham surgical trials...
Deliberative assessment of surrogate consent in dementia researchScott Y H Kim
Bioethics Program, University of Michigan, Ann Arbor, MI, USA
Alzheimers Dement 6:342-50. 2010..We therefore assessed the impact of democratic deliberation (DD), involving balanced, detailed education and peer deliberation, on the views of those responsible for persons with dementia...
Is psychiatric research stigmatized? An experimental survey of the publicJordana R Muroff
Center for Behavioral and Decision Sciences in Medicine, University of Michigan, USA
Schizophr Bull 32:129-36. 2006..Policymakers and institutional review board members may need to guard against its influence in their deliberations...
Burdens and benefits of placebos in antidepressant clinical trials: a decision and cost-effectiveness analysisScott Y H Kim
Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Am J Psychiatry 160:1272-6. 2003..The authors assessed the cost-effectiveness of entering such a trial from the perspective of potential subjects...
Long term understanding of study information in research participants with Parkinson's diseaseBernard Ravina
University of Rochester, School of Medicine and Dentistry, Department of Neurology, Rochester, NY 14610, USA
Parkinsonism Relat Disord 16:60-3. 2010..Little is known about research participants' understanding of consent information over the course of a clinical study and the relationship of this information with participant behavior...
Current state of research on decision-making competence of cognitively impaired elderly personsScott Y H Kim
Department of Psychiatry, Division of Medical Humanities, University of Rochester School of Medicine, NY 14642, USA
Am J Geriatr Psychiatry 10:151-65. 2002..It is beginning to yield findings with practical implications for preserving the autonomy and welfare of this group of vulnerable elderly patients...
Trends in the prevalence and mortality of cognitive impairment in the United States: is there evidence of a compression of cognitive morbidity?Kenneth M Langa
Division of General Medicine, Department of Medicine, University of Michigan, Ann Arbor, MI, USA
Alzheimers Dement 4:134-44. 2008..To assess the impact of these multiple trends, we compared the prevalence and 2-year mortality of cognitive impairment (CI) consistent with dementia in the United States in 1993 to 1995 and 2002 to 2004...
Utility and limits of the mini mental state examination in evaluating consent capacity in Alzheimer's diseaseScott Y H Kim
Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Psychiatr Serv 53:1322-4. 2002..Nevertheless, there may still be approaches that enhance the practical utility of the MMSE in capacity assessment...
Ethics and politics of research involving subjects with impaired decision-making abilitiesScott Y H Kim
Neurology 61:1645-6. 2003
What is the risk of sham surgery in Parkinson disease clinical trials? A review of published reportsSamuel Frank
Boston University, MA, USA
Neurology 65:1101-3. 2005..Placebo surgeries were generally safe and well tolerated but the number of subjects receiving the procedure was small. Harm occurred more frequently in subjects randomized to the experimental intervention...
Appointing a proxy for research consent after one develops dementia: the need for further studyScott Y H Kim
Neurology 66:1298-9. 2006
Interpreting the clinical significance of capacity scores for informed consent in Alzheimer disease clinical trialsJason Karlawish
Department of Medicine, Alzheimer s Disease Center, Leonard Davis Institute for Health Economics, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, School of Medicine, PA, USA
Am J Geriatr Psychiatry 16:568-74. 2008..Among Alzheimer disease (AD) patients enrolled in a clinical trial, the authors assessed the ability of a standardized capacity assessment procedure to identify persons who are capable of giving their own informed consent...
Ethics of sham surgery: perspective of patientsSamuel A Frank
Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA
Mov Disord 23:63-8. 2008..Future research needs to determine whether eliciting more considered judgments of laypersons would reveal different levels of support for sham surgery...
The views of Alzheimer disease patients and their study partners on proxy consent for clinical trial enrollmentJason Karlawish
Department of Medicine, Alzheimer s Disease Center, Leonard Davis Institute for Health Economics, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA
Am J Geriatr Psychiatry 16:240-7. 2008..To examine the views of Alzheimer disease (AD) patients and their study partners on the ethics of proxy consent for clinical research...
The sham surgery debate and the moral complexity of risk-benefit analysisScott Y H Kim
University of Rochester
Am J Bioeth 3:68-70. 2003
Research Grants
- Competence to Consent in Schizophrenia ResearchScott Kim; Fiscal Year: 2005..abstract_text> ..
- Therapeutic Misconception and the Ethics of Sham Surgery Controls in PD ResearchScott Y Kim; Fiscal Year: 2010..Specifically, the results of this study will provide important insights into how to minimize or even eliminate serious misconceptions or misunderstandings on the part of participants that may compromise the quality of their consent. ..
- Capacity to Appoint a Proxy for Research ConsentScott Kim; Fiscal Year: 2009..abstract_text> ..
- Therapeutic Misconception and the Ethics of Sham Surgery Controls in PD ResearchScott Kim; Fiscal Year: 2009..Specifically, the results of this study will provide important insights into how to minimize or even eliminate serious misconceptions or misunderstandings on the part of participants that may compromise the quality of their consent. ..
- Ethics of Surrogate Consent for Dementia ResearchScott Kim; Fiscal Year: 2009....
- Ethics of Surrogate Consent for Dementia ResearchScott Kim; Fiscal Year: 2007....
- Capacity to Appoint a Proxy for Research ConsentScott Kim; Fiscal Year: 2007..abstract_text> ..
- Ethics of Surrogate Consent for Dementia ResearchScott Y Kim; Fiscal Year: 2010....
