Sangwon F Kim

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Maturation and activity of sterol regulatory element binding protein 1 is inhibited by acyl-CoA binding domain containing 3
    Yong Chen
    Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e49906. 2012
  2. pmc Animal models of eating disorders
    S F Kim
    Center for Neurobiology and Behavior, Department of Psychiatry and Pharmacology, The Perelman School of Medicine University of Pennsylvania, 125 S 31st St, TRL Rm 2207, Philadelphia, PA 19104, USA
    Neuroscience 211:2-12. 2012
  3. pmc The role of nitric oxide in prostaglandin biology; update
    Sangwon F Kim
    Department of Psychiatry and Pharmacology, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, 125 S, 31st St TRL Rm 2207, Philadelphia, PA 19104, USA
    Nitric Oxide 25:255-64. 2011
  4. pmc Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity
    Yong Chen
    Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 33:3582-7. 2013
  5. pmc Atypical antipsychotics and the neural regulation of food intake and peripheral metabolism
    Karen L Teff
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA
    Physiol Behav 104:590-8. 2011
  6. pmc AMP-activated protein kinase is physiologically regulated by inositol polyphosphate multikinase
    Sookhee Bang
    Department of Psychiatry, Center for Neurobiology and Behavior, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 109:616-20. 2012
  7. pmc Striatum specific protein, Rhes regulates AKT pathway
    Sookhee Bang
    Department of Psychiatry and Pharmacology, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, 125 S 31st St, TRL Rm 2207, Philadelphia, PA 19104, United States
    Neurosci Lett 521:142-7. 2012
  8. pmc Convergence of IPMK and LKB1-AMPK signaling pathways on metformin action
    Sookhee Bang
    Department of Psychiatry and Pharmacology, Center for Neurobiology and Behavior S B, Y C, S F K and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism and the Institute for Diabetes, Obesity, and Metabolism R S A, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104
    Mol Endocrinol 28:1186-93. 2014
  9. pmc High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice
    Steven E Arnold
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, 125 South 31st St, Philadelphia, PA 19104, USA Electronic address
    Neurobiol Dis 67:79-87. 2014

Research Grants

Collaborators

Detail Information

Publications9

  1. pmc Maturation and activity of sterol regulatory element binding protein 1 is inhibited by acyl-CoA binding domain containing 3
    Yong Chen
    Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e49906. 2012
    ..These findings suggest that ACBD3 plays an essential role in maintaining lipid homeostasis via regulating SREBP1's processing pathway and thus impacting cellular lipogenesis...
  2. pmc Animal models of eating disorders
    S F Kim
    Center for Neurobiology and Behavior, Department of Psychiatry and Pharmacology, The Perelman School of Medicine University of Pennsylvania, 125 S 31st St, TRL Rm 2207, Philadelphia, PA 19104, USA
    Neuroscience 211:2-12. 2012
    ..Therefore, this review will serve to focus on the basic clinical features of eating disorders and the current advances in animal models of eating disorders...
  3. pmc The role of nitric oxide in prostaglandin biology; update
    Sangwon F Kim
    Department of Psychiatry and Pharmacology, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, 125 S, 31st St TRL Rm 2207, Philadelphia, PA 19104, USA
    Nitric Oxide 25:255-64. 2011
    ..This review will focus in particular on recent advances in this field that extend our understanding of these two pathways under various systems...
  4. pmc Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity
    Yong Chen
    Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 33:3582-7. 2013
    ..Deletion of Dexras1 in mice attenuates NO-mediated cell death in dissociated primary cortical neurons and retinal ganglion cells in vivo. Thus, Dexras1 appears to mediate NMDA-elicited neurotoxicity via NO and iron influx...
  5. pmc Atypical antipsychotics and the neural regulation of food intake and peripheral metabolism
    Karen L Teff
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA
    Physiol Behav 104:590-8. 2011
    ..Furthermore, we examine how inhibition of the histaminergic pathway may mediate increases in food intake and the potential role of the vagus nerve in the reported peripheral metabolic effects...
  6. pmc AMP-activated protein kinase is physiologically regulated by inositol polyphosphate multikinase
    Sookhee Bang
    Department of Psychiatry, Center for Neurobiology and Behavior, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 109:616-20. 2012
    ..Regulation by glucose of phospho-AMPK in hypothalamic cell lines is prevented by blocking AMPK-IPMK binding. These findings imply that IPMK inhibitors will be beneficial in treating obesity and diabetes...
  7. pmc Striatum specific protein, Rhes regulates AKT pathway
    Sookhee Bang
    Department of Psychiatry and Pharmacology, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, 125 S 31st St, TRL Rm 2207, Philadelphia, PA 19104, United States
    Neurosci Lett 521:142-7. 2012
    ..These findings suggest that Rhes is a novel striatal regulator of the AKT-mediated pathway in the striatum...
  8. pmc Convergence of IPMK and LKB1-AMPK signaling pathways on metformin action
    Sookhee Bang
    Department of Psychiatry and Pharmacology, Center for Neurobiology and Behavior S B, Y C, S F K and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism and the Institute for Diabetes, Obesity, and Metabolism R S A, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104
    Mol Endocrinol 28:1186-93. 2014
    ..Our data demonstrate that IPMK plays an important role in LKB1/AMPK signaling and may be targeted for treatment of metabolic diseases. ..
  9. pmc High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice
    Steven E Arnold
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, 125 South 31st St, Philadelphia, PA 19104, USA Electronic address
    Neurobiol Dis 67:79-87. 2014
    ..These findings indicate that HFD is associated with telencephalic insulin resistance and deleterious effects on synaptic integrity and cognitive behaviors...

Research Grants3

  1. Molecular basis of atypical antipsychotic drugs-induced weight gain
    Sangwon F Kim; Fiscal Year: 2010
    ..Hence, it is upmost importance to identify the molecular mechanism of how AAPDs lead to an excessive weight gain. ..