Research Topics
| S Y H KimSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Trust in early phase research: therapeutic optimism and protective pessimismScott Y H Kim
Department of Psychiatry, the Bioethics Program, The Center for Behavioral and Decision Sciences in Medicine, University of Michigan, 300 North Ingalls Street, 7C27, Ann Arbor, MI, 48109, USA
Med Health Care Philos 11:393-401. 2008..We discuss this discrepancy using "frameworks of trust" and demonstrate the need to incorporate these frameworks into the existing model of informed consent...
Science and ethics of sham surgery: a survey of Parkinson disease clinical researchersScott Y H Kim
Department of Psychiatry, Bioethics Program, Center for Behavioral and Decision Sciences in Medicine, University of Michigan, Ann Arbor, 48109, USA
Arch Neurol 62:1357-60. 2005..Sham surgery is used in neurosurgical clinical trials in Parkinson disease (PD) but remains controversial. The controversy may be compounded when gene-transfer technologies are tested in sham surgical trials...
When does decisional impairment become decisional incompetence? Ethical and methodological issues in capacity research in schizophreniaScott Y H Kim
Department of Psychiatry, University of Michigan, 300 North Ingalls Street, 7C27, Ann Arbor, MI 48109, USA
Schizophr Bull 32:92-7. 2006..Future research needs are outlined...- What do people at risk for Alzheimer disease think about surrogate consent for research?Scott Y H Kim
Department of Psychiatry, Center for Behavioral and Decision Sciences in Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
Neurology 65:1395-401. 2005..Research involving decisionally incapable adults remains an unsettled and controversial policy issue, especially for protocols that involve significant risk to participants. Few data exist to guide policymakers and IRBs.. - Volunteering for early phase gene transfer research in Parkinson diseaseS Y H Kim
Department of Psychiatry, Bioethics Program, Center for Behavioral and Decision Sciences in Medicine, University of Michigan, Ann Arbor, USA
Neurology 66:1010-5. 2006..Recently, some have expressed concern that patients with PD may have unrealistic expectations... - Surrogate consent for dementia research: a national survey of older AmericansS Y H Kim
Bioethics Program, University of Michigan, Ann Arbor, MI 48109, USA
Neurology 72:149-55. 2009..Because AD impairs decisional capacity, informed consent often must come from surrogates, usually close family members. But policies for surrogate consent for research remain unsettled after decades of debate... - Do clinicians follow a risk-sensitive model of capacity-determination? An experimental video surveyScott Y H Kim
Dept of Psychiatry, the Bioethics Program, and the Center for Behavioral and Decision Sciences in Medicine, Univ of Michigan, MI, USA
Psychosomatics 47:325-9. 2006..Thus, clinicians, in fact, use the normative risk-sensitive model for capacity, but there remains considerable unexplained variability in their judgments... - The capacity to appoint a proxy and the possibility of concurrent proxy directivesScott Y H Kim
University of Michigan Bioethics Program, Ann Arbor, MI 48109 0429, USA
Behav Sci Law 24:469-78. 2006..We first propose a rationale for assessing the capacity to appoint a proxy and then describe a novel interview instrument for assessing the capacity to appoint a proxy for research consent... - Determining when impairment constitutes incapacity for informed consent in schizophrenia researchScott Y H Kim
Department of Psychiatry, Bioethics Program, and Center for Behavioral and Decision Sciences in Medicine, University of Michigan, 300 North Ingalls, Ann Arbor, MI 48109 0429, and Massachusetts General Hospital, Boston, USA
Br J Psychiatry 191:38-43. 2007..Although people with schizophrenia display impaired abilities for consent, it is not known how much impairment constitutes incapacity... - Deliberative assessment of surrogate consent in dementia researchScott Y H Kim
Bioethics Program, University of Michigan, Ann Arbor, MI, USA
Alzheimers Dement 6:342-50. 2010..We therefore assessed the impact of democratic deliberation (DD), involving balanced, detailed education and peer deliberation, on the views of those responsible for persons with dementia... - Preservation of the capacity to appoint a proxy decision maker: implications for dementia researchScott Y H Kim
Center Bioethics and Social Sciences in Medicine, and Department of Psychiatry, University of Michigan, 300 N Ingalls St, 7C27, Ann Arbor, MI 48109, USA
Arch Gen Psychiatry 68:214-20. 2011..If individuals incapable of consenting to research studies were able to appoint a research proxy, it would allow for an appointed surrogate (rather than a de facto surrogate) to represent the subject... - Impaired decision-making ability in subjects with Alzheimer's disease and willingness to participate in researchScott Y H Kim
Department of Psychiatry, University of Rochester School of Medicne and Dentistry, NY 14642, USA
Am J Psychiatry 159:797-802. 2002..The authors examined the effects of cognitive and decisional impairment on willingness to participate in research among persons with Alzheimer's disease... - Effect of public deliberation on attitudes toward surrogate consent for dementia researchS Y H Kim
Center for Bioethics and Social Sciences in Medicine, University of Michigan, Ann Arbor 48109, USA
Neurology 77:2097-104. 2011..To assess the informed, deliberative views of the older general public toward a policy of allowing surrogate consent for Alzheimer disease (AD) research... - Benefits and burdens of placebos in psychiatric researchScott Y H Kim
Department of Psychiatry, University of Rochester School of Medicine and Dentistry, 300 Crittenden Boulevard, Rochester, NY 14642, USA
Psychopharmacology (Berl) 171:13-8. 2003..Current practice permits placebos in such settings, as long as the benefits outweigh the risks and burdens... - Potential research participants' views regarding researcher and institutional financial conflicts of interestS Y H Kim
Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, USA
J Med Ethics 30:73-9. 2004..While data exist on the perspectives and roles of academic institutions, investigators, industry sponsors, and scientific journals, little is known about the perspectives of potential research participants... - The dilemma of hidden ethical dilemmasScott Y H Kim
Department of Psychiatry, the Bioethics Program, and the Program for Improving Health Care Decisions, University of Michigan Medical School, 300 North Ingalls, 7C27, Ann Arbor, MI 48109, USA
Acad Psychiatry 28:168-9. 2004 - Returning individual research results: development of a cancer genetics education and risk communication protocolJ Scott Roberts
Department of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, MI 48109 2029, USA
J Empir Res Hum Res Ethics 5:17-30. 2010.... - Proxy and surrogate consent in geriatric neuropsychiatric research: update and recommendationsScott Y H Kim
Department of Psychiatry and the Program in Clinical Ethics, University of Rochester Medical Center, Rochester, NY, USA
Am J Psychiatry 161:797-806. 2004..The authors provide an updated discussion, critique, and recommendations regarding the need for clear legal and regulatory policy on this issue... - Assessing the public's views in research ethics controversies: deliberative democracy and bioethics as natural alliesScott Y H Kim
University of Michigan, Ann Arbor, MI 48109, USA
J Empir Res Hum Res Ethics 4:3-16. 2009..The potential pitfalls of DD and the means of minimizing them as well as future research directions are also discussed... - Advance directives and outcomes of surrogate decision making before deathMaria J Silveira
Veterans Affairs Center for Clinical Management Research, and Division of General Medicine, University of Michigan, Ann Arbor, USA
N Engl J Med 362:1211-8. 2010..Recent discussions about health care reform have raised questions regarding the value of advance directives... - Evidence-based ethics for neurology and psychiatry researchScott Y H Kim
Department of Psychiatry, Bioethics Program, and Program for Improving Health Care Decisions, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
NeuroRx 1:372-7. 2004..For each of these issues, selected empirical data are reviewed, areas for further inquiry are noted, and the need for development of novel methods for bioethics policy research is discussed... - Disclosing individual CDKN2A research results to melanoma survivors: interest, impact, and demands on researchersKurt D Christensen
Department of Health Behavior and Health Education, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109 2029, USA
Cancer Epidemiol Biomarkers Prev 20:522-9. 2011..Whether to return individual research results from cancer genetics studies is widely debated, but little is known about how participants respond to results disclosure or about its time and cost burdens on investigators... - Assessing and communicating the risks and benefits of gene transfer clinical trialsScott Y H Kim
Bioethics Program, University of Michigan Medical School, 300 North Ingalls Street, Ann Arbor, MI 48109 0429, USA
Curr Opin Mol Ther 8:384-9. 2006.... - Is psychiatric research stigmatized? An experimental survey of the publicJordana R Muroff
Center for Behavioral and Decision Sciences in Medicine, University of Michigan, USA
Schizophr Bull 32:129-36. 2006..Policymakers and institutional review board members may need to guard against its influence in their deliberations... - Family matters: a social system perspective on physician-assisted suicide and the older adultD A King
Department of Psychiatry, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, New York 14642, USA
Psychol Public Policy Law 6:434-51. 2000.... - Ethics of sham surgery: perspective of patientsSamuel A Frank
Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA
Mov Disord 23:63-8. 2008..Future research needs to determine whether eliciting more considered judgments of laypersons would reveal different levels of support for sham surgery... - Burdens and benefits of placebos in antidepressant clinical trials: a decision and cost-effectiveness analysisScott Y H Kim
Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Am J Psychiatry 160:1272-6. 2003..The authors assessed the cost-effectiveness of entering such a trial from the perspective of potential subjects... - Current state of research on decision-making competence of cognitively impaired elderly personsScott Y H Kim
Department of Psychiatry, Division of Medical Humanities, University of Rochester School of Medicine, NY 14642, USA
Am J Geriatr Psychiatry 10:151-65. 2002..It is beginning to yield findings with practical implications for preserving the autonomy and welfare of this group of vulnerable elderly patients... - Utility and limits of the mini mental state examination in evaluating consent capacity in Alzheimer's diseaseScott Y H Kim
Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Psychiatr Serv 53:1322-4. 2002..Nevertheless, there may still be approaches that enhance the practical utility of the MMSE in capacity assessment... - The views of Alzheimer disease patients and their study partners on proxy consent for clinical trial enrollmentJason Karlawish
Department of Medicine, Alzheimer s Disease Center, Leonard Davis Institute for Health Economics, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA
Am J Geriatr Psychiatry 16:240-7. 2008..To examine the views of Alzheimer disease (AD) patients and their study partners on the ethics of proxy consent for clinical research... - Ethics and politics of research involving subjects with impaired decision-making abilitiesScott Y H Kim
Neurology 61:1645-6. 2003 - What is the risk of sham surgery in Parkinson disease clinical trials? A review of published reportsSamuel Frank
Boston University, MA, USA
Neurology 65:1101-3. 2005..Placebo surgeries were generally safe and well tolerated but the number of subjects receiving the procedure was small. Harm occurred more frequently in subjects randomized to the experimental intervention... - Appointing a proxy for research consent after one develops dementia: the need for further studyScott Y H Kim
Neurology 66:1298-9. 2006 - Interpreting the clinical significance of capacity scores for informed consent in Alzheimer disease clinical trialsJason Karlawish
Department of Medicine, Alzheimer s Disease Center, Leonard Davis Institute for Health Economics, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, School of Medicine, PA, USA
Am J Geriatr Psychiatry 16:568-74. 2008..Among Alzheimer disease (AD) patients enrolled in a clinical trial, the authors assessed the ability of a standardized capacity assessment procedure to identify persons who are capable of giving their own informed consent... - The sham surgery debate and the moral complexity of risk-benefit analysisScott Y H Kim
University of Rochester
Am J Bioeth 3:68-70. 2003 - Patients' views on suicidality and antidepressantsJordana R Muroff
Psychiatr Serv 57:723-4. 2006