Kyoungmi Kim

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc A jackknife and voting classifier approach to feature selection and classification
    Sandra L Taylor
    Division of Biostatistics, Department of Public Health Sciences, University of California School of Medicine, Davis, CA, USA
    Cancer Inform 10:133-47. 2011
  2. pmc Expectations, validity, and reality in gene expression profiling
    Kyoungmi Kim
    Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, CA 95616, USA
    J Clin Epidemiol 63:950-9. 2010
  3. doi request reprint Genes and networks expressed in perioperative omental adipose tissue are correlated with weight loss from Roux-en-Y gastric bypass
    K Kim
    Rowe Program in Human Genetics, University of California, Davis, CA 95616, USA
    Int J Obes (Lond) 32:1395-406. 2008
  4. pmc The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction
    Yana Chen
    VM Molecular Biosciences, University of California, Davis, CA, USA
    Biosci Rep 33:83-95. 2013
  5. pmc Kidney tumor biomarkers revealed by simultaneous multiple matrix metabolomics analysis
    Sheila Ganti
    Division of Nephrology, Department of Internal Medicine, University of California, Davis, California 95616, USA
    Cancer Res 72:3471-9. 2012
  6. doi request reprint Lean mass and insulin resistance in women with polycystic ovary syndrome
    Kevin B Comerford
    Nutritional Biology Graduate Group, Department of Nutrition, The University of California at Davis, Davis, California, USA
    Metabolism 61:1256-60. 2012
  7. pmc Metabolic and endocrine effects of long-chain versus essential omega-3 polyunsaturated fatty acids in polycystic ovary syndrome
    M Luisa Vargas
    Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, University of California at Davis, Davis, CA 95817, USA
    Metabolism 60:1711-8. 2011
  8. pmc The influence of shc proteins and aging on whole body energy expenditure and substrate utilization in mice
    Jennifer H Stern
    VM Molecular Biosciences, University of California Davis, Davis, California, USA
    PLoS ONE 7:e48790. 2012
  9. pmc Urinary acylcarnitines are altered in human kidney cancer
    Sheila Ganti
    Division of Nephrology, Department of Internal Medicine, University of California, Davis, CA 95616, USA
    Int J Cancer 130:2791-800. 2012
  10. pmc Female CGG knock-in mice modeling the fragile X premutation are impaired on a skilled forelimb reaching task
    Amanda A Diep
    Department of Neurological Surgery, School of Medicine, University of California, Davis, Davis, CA 95616, USA
    Neurobiol Learn Mem 97:229-34. 2012

Collaborators

Detail Information

Publications27

  1. pmc A jackknife and voting classifier approach to feature selection and classification
    Sandra L Taylor
    Division of Biostatistics, Department of Public Health Sciences, University of California School of Medicine, Davis, CA, USA
    Cancer Inform 10:133-47. 2011
    ....
  2. pmc Expectations, validity, and reality in gene expression profiling
    Kyoungmi Kim
    Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, CA 95616, USA
    J Clin Epidemiol 63:950-9. 2010
    ..To provide a critical overview of gene expression profiling methodology and discuss areas of future development...
  3. doi request reprint Genes and networks expressed in perioperative omental adipose tissue are correlated with weight loss from Roux-en-Y gastric bypass
    K Kim
    Rowe Program in Human Genetics, University of California, Davis, CA 95616, USA
    Int J Obes (Lond) 32:1395-406. 2008
    ..In addition, the mechanisms of action in accomplishing major weight loss as well as the explanation for the variable weight loss have not been established...
  4. pmc The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction
    Yana Chen
    VM Molecular Biosciences, University of California, Davis, CA, USA
    Biosci Rep 33:83-95. 2013
    ..These results indicate that dietary lipid composition does influence liver mitochondrial phospholipid composition, ROS production, proton leak and ETC enzyme activities in CR animals...
  5. pmc Kidney tumor biomarkers revealed by simultaneous multiple matrix metabolomics analysis
    Sheila Ganti
    Division of Nephrology, Department of Internal Medicine, University of California, Davis, California 95616, USA
    Cancer Res 72:3471-9. 2012
    ....
  6. doi request reprint Lean mass and insulin resistance in women with polycystic ovary syndrome
    Kevin B Comerford
    Nutritional Biology Graduate Group, Department of Nutrition, The University of California at Davis, Davis, California, USA
    Metabolism 61:1256-60. 2012
    ..7±1.7 and 48.9±1.6 kg) but discordant for fat mass (43.3±2.6 vs 30.3±8.9 kg) showed no differences in insulin resistance parameters. These novel findings indicate that lean mass relates directly to insulin resistance in PCOS...
  7. pmc Metabolic and endocrine effects of long-chain versus essential omega-3 polyunsaturated fatty acids in polycystic ovary syndrome
    M Luisa Vargas
    Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, University of California at Davis, Davis, CA 95817, USA
    Metabolism 60:1711-8. 2011
    ..Long-chain vs essential n-3 PUFA-rich oils have distinct metabolic and endocrine effects in polycystic ovary syndrome; and therefore, they should not be used interchangeably...
  8. pmc The influence of shc proteins and aging on whole body energy expenditure and substrate utilization in mice
    Jennifer H Stern
    VM Molecular Biosciences, University of California Davis, Davis, California, USA
    PLoS ONE 7:e48790. 2012
    ..The results of this study indicate that both Shc proteins and aging should be considered as factors that influence energy expenditure in mice...
  9. pmc Urinary acylcarnitines are altered in human kidney cancer
    Sheila Ganti
    Division of Nephrology, Department of Internal Medicine, University of California, Davis, CA 95616, USA
    Int J Cancer 130:2791-800. 2012
    ..Furthermore, these findings open up a new area of investigation into the metabolic basis of kidney cancer...
  10. pmc Female CGG knock-in mice modeling the fragile X premutation are impaired on a skilled forelimb reaching task
    Amanda A Diep
    Department of Neurological Surgery, School of Medicine, University of California, Davis, Davis, CA 95616, USA
    Neurobiol Learn Mem 97:229-34. 2012
    ..The results demonstrate that female CGG KI mice show deficits for learning a skilled forelimb reaching task compared to wildtype littermates, and that these deficits worsen with increasing CGG repeat lengths...
  11. pmc CGG trinucleotide repeat length modulates neural plasticity and spatiotemporal processing in a mouse model of the fragile X premutation
    Michael R Hunsaker
    Department of Neurological Surgery, School of Medicine, University of California Davis, Davis, CA 95616, USA
    Hippocampus 22:2260-75. 2012
    ..These data provide evidence for a neurocognitive endophenotype in the CGG KI mouse model of the premutation in which CGG repeat length negatively modulates plasticity and spatiotemporal attention...
  12. doi request reprint Increased soluble leptin receptor levels in morbidly obese patients with insulin resistance and nonalcoholic fatty liver disease
    Valentina Medici
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of California Davis Medical Center, Sacramento, California, USA
    Obesity (Silver Spring) 18:2268-73. 2010
    ..In conclusion, increased SLR levels in morbidly obese patients with diabetes are correlated with the stage of liver fibrosis, and may reflect progressive liver disease...
  13. pmc Serum fatty acid binding protein 4, free fatty acids, and metabolic risk markers
    SIDIKA E KARAKAS
    Department of Internal Medicine, Division of Endocrinology, Clinical Nutrition and Vascular Medicine, The University of California at Davis, Davis, CA 95817, USA
    Metabolism 58:1002-7. 2009
    ..In conclusion, fasting FABP4 related to metabolic risk markers more strongly than fasting FFA. Nadir FABP4 and nadir FFA measured after glucose loading may provide better risk assessment than the fasting values...
  14. doi request reprint Mealtime, temporal, and daily variability of the human urinary and plasma metabolomes in a tightly controlled environment
    Kyoungmi Kim
    Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, Davis, California, United States of America
    PLoS ONE 9:e86223. 2014
    ..In light of these findings, future metabolomics studies should consider these sources of variability to allow for appropriate metabolomics testing and reliable clinical translation of metabolomics data. ..
  15. pmc Urine metabolomic analysis identifies potential biomarkers and pathogenic pathways in kidney cancer
    Kyoungmi Kim
    Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California 95616, USA
    OMICS 15:293-303. 2011
    ..Further evaluation of the global metabolomics analysis, as well as confirmation of the specific potential biomarkers using a larger sample size, will lead to new avenues of kidney cancer diagnosis and therapy...
  16. pmc A metabolomics approach using juvenile cystic mice to identify urinary biomarkers and altered pathways in polycystic kidney disease
    Sandra L Taylor
    Division of Biostatistics, Department of Public Health Sciences, University of California Davis, Davis, CA 95616, USA
    Am J Physiol Renal Physiol 298:F909-22. 2010
    ..Thus, urine metabolomics has great diagnostic potential for cystic renal disorders and deserves further study...
  17. pmc Shc proteins influence the activities of enzymes involved in fatty acid oxidation and ketogenesis
    Kevork Hagopian
    Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Metabolism 61:1703-13. 2012
    ..To investigate this idea, the activities of β-oxidation and ketone body metabolism enzymes were measured...
  18. doi request reprint Metabolomics in the study of kidney diseases
    Robert H Weiss
    Division of Nephrology, Department of Internal Medicine, Genome and Biomedical Sciences Building, Room 6312, University of California, Davis, CA 95616, USA
    Nat Rev Nephrol 8:22-33. 2012
    ..Thus, metabolomics holds promise for early diagnosis, increased choice of therapy and the identification of new metabolic pathways that could potentially be targeted in kidney disease...
  19. pmc Chip-based nLC-TOF-MS is a highly stable technology for large-scale high-throughput analyses
    L Renee Ruhaak
    Department of Chemistry, University of California Davis, Davis, CA 95616, USA
    Anal Bioanal Chem 405:4953-8. 2013
    ..Overall, chip-based nano-LC-MS appears to be a highly stable technology, which is suitable for the profiling of large numbers of clinical samples for biomarker discovery...
  20. pmc Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease
    Valentina Medici
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of California Davis, Davis, CA 95817, USA
    Hepatology 57:555-65. 2013
    ..PCA treatment of tx-j mice reduced Tnf-α and ALT levels, betaine treatment increased S-adenosylmethionine and up-regulated Dnmt3b levels, and both treatments restored global DNA methylation levels...
  21. pmc The influence of acute, late-life calorie restriction on whole body energy metabolism in p66Shc(-/-) mice
    Jennifer H Stern
    VM Molecular Biosciences, University of California, Davis, CA 95616, USA
    Mech Ageing Dev 133:414-20. 2012
    ..The results indicate that p66Shc does not significantly influence EE in 18 mo mice at baseline or 2 mo of CR, although it may play a role in the EE response to very acute CR...
  22. pmc Age as a modulator of inflammatory cardiovascular risk factors
    Erdembileg Anuurad
    Department of Medicine, University of California, Davis, Sacramento, CA 95817, USA
    Arterioscler Thromb Vasc Biol 31:2151-6. 2011
    ..We assessed the relationship with age of inflammatory markers, representing (1) systemic (C-reactive protein, fibrinogen, and serum amyloid-A) and (2) vascular (lipoprotein-associated phospholipase A(2) and pentraxin-3) inflammation...
  23. pmc Motor deficits on a ladder rung task in male and female adolescent and adult CGG knock-in mice
    Michael R Hunsaker
    Department of Neurological Surgery, School of Medicine, University of California, Davis Davis, CA 95616, USA
    Behav Brain Res 222:117-21. 2011
    ..The results demonstrate that both male and female CGG KI mice showed a greater number of foot slips as a function of increased CGG repeat length, independent of the age of the animal or general activity level...
  24. pmc Determinants of impaired fasting glucose versus glucose intolerance in polycystic ovary syndrome
    SIDIKA E KARAKAS
    Department of Internal Medicine, Division of Endocrinology, Clinical Nutrition and Vascular Medicine, University of California, Davis, Davis, California, USA
    Diabetes Care 33:887-93. 2010
    ..To determine insulin resistance and response in patients with polycystic ovary syndrome (PCOS) and normal glucose tolerance (NGT), impaired fasting glucose (IFG), impaired glucose tolerance, and combined glucose intolerance (CGI)...
  25. pmc In polycystic ovary syndrome, adrenal steroids are regulated differently in the morning versus in response to nutrient intake
    Dumindra Gurusinghe
    Department of Internal Medicine, Division of Endocrinology, Clinical Nutrition and Vascular Medicine, The University of California at Davis, Davis, California, USA
    Fertil Steril 93:1192-9. 2010
    ..To investigate adrenal steroid regulation in polycystic ovary syndrome...
  26. pmc Synergistic role of inflammation and insulin resistance as coronary artery disease risk factors in African Americans and Caucasians
    Erdembileg Anuurad
    Department of Medicine, University of California, Davis, CA 95817, United States
    Atherosclerosis 205:290-5. 2009
    ..Further, a combination of IR and inflammation resulted in a higher degree of CAD in both Caucasians and African Americans. The results suggest that inflammation may potentiate the cardiovascular risk factor role of IR...
  27. ncbi request reprint Identification of positional candidate genes for body weight and adiposity in subcongenic mice
    Sally Chiu
    Rowe Program in Genetics, University of California, Davis, California 95616, USA
    Physiol Genomics 31:75-85. 2007
    ..Using subcongenic mapping, we successfully narrowed a body weight and obesity QTL interval and identified PC2 as a positional candidate gene...