Hyunki Kim

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Suppression of human selenium-binding protein 1 is a late event in colorectal carcinogenesis and is associated with poor survival
    Hyunki Kim
    Department of Pathology, Yonsei University College of Medicine, Seoul, Korea
    Proteomics 6:3466-76. 2006
  2. pmc Extracelluar matrix metalloproteinase as a novel target for pancreatic cancer therapy
    Hyunki Kim
    Department of Radiology, University of Alabama at Birmingham, USA
    Anticancer Drugs 22:864-74. 2011
  3. ncbi request reprint Pancreatic adenocarcinoma: a pilot study of quantitative perfusion and diffusion-weighted breath-hold magnetic resonance imaging
    Hyunki Kim
    Departments of Radiology, University of Alabama at Birmingham, Birmingham, AL, 35294 0019, USA
    Abdom Imaging 39:744-52. 2014
  4. pmc Antagonistic effects of anti-EMMPRIN antibody when combined with chemotherapy against hypovascular pancreatic cancers
    Hyunki Kim
    Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, 35294 0019, USA
    Mol Imaging Biol 16:85-94. 2014
  5. pmc Dual combination therapy targeting DR5 and EMMPRIN in pancreatic adenocarcinoma
    Hyunki Kim
    Department of Radiology, University of Alabama at Birmingham, 1670 University Blvd, Birmingham, AL 35294, USA
    Mol Cancer Ther 11:405-15. 2012
  6. pmc SemiSPECT: a small-animal single-photon emission computed tomography (SPECT) imager based on eight cadmium zinc telluride (CZT) detector arrays
    Hyunki Kim
    College of Optical Sciences, University of Arizona, Tucson, Arizona 85724, USA
    Med Phys 33:465-74. 2006
  7. pmc Early therapy evaluation of combined cetuximab and irinotecan in orthotopic pancreatic tumor xenografts by dynamic contrast-enhanced magnetic resonance imaging
    Hyunki Kim
    Departments of Radiology, Comprehensive Cancer Center, University of Alabama at Birmingham, AL 35294 0012, USA
    Mol Imaging 10:153-67. 2011
  8. ncbi request reprint DCE-MRI detects early vascular response in breast tumor xenografts following anti-DR5 therapy
    Hyunki Kim
    The Department of Radiology, University of Alabama at Birmingham, AL 35294, USA
    Mol Imaging Biol 13:94-103. 2011
  9. pmc (18)F-FDG PET/CT imaging detects therapy efficacy of anti-EMMPRIN antibody and gemcitabine in orthotopic pancreatic tumor xenografts
    Nemil Shah
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Mol Imaging Biol 14:237-44. 2012
  10. pmc Early therapy evaluation of combined anti-death receptor 5 antibody and gemcitabine in orthotopic pancreatic tumor xenografts by diffusion-weighted magnetic resonance imaging
    Hyunki Kim
    Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0012, USA
    Cancer Res 68:8369-76. 2008

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Suppression of human selenium-binding protein 1 is a late event in colorectal carcinogenesis and is associated with poor survival
    Hyunki Kim
    Department of Pathology, Yonsei University College of Medicine, Seoul, Korea
    Proteomics 6:3466-76. 2006
    ..Our findings indicate that suppression of SELENBP1 is a frequent and late event in colorectal carcinogenesis, and may contribute to the rapid progression of colorectal carcinoma...
  2. pmc Extracelluar matrix metalloproteinase as a novel target for pancreatic cancer therapy
    Hyunki Kim
    Department of Radiology, University of Alabama at Birmingham, USA
    Anticancer Drugs 22:864-74. 2011
    ..049). These data show the high potential of anti-EMMPRIN therapy for pancreatic cancer and support its clinical translation...
  3. ncbi request reprint Pancreatic adenocarcinoma: a pilot study of quantitative perfusion and diffusion-weighted breath-hold magnetic resonance imaging
    Hyunki Kim
    Departments of Radiology, University of Alabama at Birmingham, Birmingham, AL, 35294 0019, USA
    Abdom Imaging 39:744-52. 2014
    ..To confirm the feasibility of breath-hold DCE-MRI and DWI at 3T to obtain the intra-abdominal quantitative physiologic parameters, K(trans), k ep, and ADC, in patients with untreated pancreatic ductal adenocarcinomas...
  4. pmc Antagonistic effects of anti-EMMPRIN antibody when combined with chemotherapy against hypovascular pancreatic cancers
    Hyunki Kim
    Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, 35294 0019, USA
    Mol Imaging Biol 16:85-94. 2014
    ..To examine the antagonistic effects of anti-extracellular matrix metalloprotease inducer (anti-EMMPRIN) antibody when combined with chemotherapy using a hypovascular pancreatic tumor model...
  5. pmc Dual combination therapy targeting DR5 and EMMPRIN in pancreatic adenocarcinoma
    Hyunki Kim
    Department of Radiology, University of Alabama at Birmingham, 1670 University Blvd, Birmingham, AL 35294, USA
    Mol Cancer Ther 11:405-15. 2012
    ..Tumor growth was significantly suppressed by the combination therapy, and the additive effect of the combination was shown in both MIA PaCa-2 and PANC-1 tumor models...
  6. pmc SemiSPECT: a small-animal single-photon emission computed tomography (SPECT) imager based on eight cadmium zinc telluride (CZT) detector arrays
    Hyunki Kim
    College of Optical Sciences, University of Arizona, Tucson, Arizona 85724, USA
    Med Phys 33:465-74. 2006
    ....
  7. pmc Early therapy evaluation of combined cetuximab and irinotecan in orthotopic pancreatic tumor xenografts by dynamic contrast-enhanced magnetic resonance imaging
    Hyunki Kim
    Departments of Radiology, Comprehensive Cancer Center, University of Alabama at Birmingham, AL 35294 0012, USA
    Mol Imaging 10:153-67. 2011
    ..002), and proliferating cell densities (p  =  .001). This study supports the clinical use of DCE-MRI for pancreatic cancer patients for early assessment of an anti-epidermal growth factor receptor therapy combined with chemotherapy...
  8. ncbi request reprint DCE-MRI detects early vascular response in breast tumor xenografts following anti-DR5 therapy
    Hyunki Kim
    The Department of Radiology, University of Alabama at Birmingham, AL 35294, USA
    Mol Imaging Biol 13:94-103. 2011
    ..Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) measured the early vascular changes after administration of TRA-8, bevacizumab, or TRA-8 combined with bevacizumab in breast tumor xenografts...
  9. pmc (18)F-FDG PET/CT imaging detects therapy efficacy of anti-EMMPRIN antibody and gemcitabine in orthotopic pancreatic tumor xenografts
    Nemil Shah
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Mol Imaging Biol 14:237-44. 2012
    ....
  10. pmc Early therapy evaluation of combined anti-death receptor 5 antibody and gemcitabine in orthotopic pancreatic tumor xenografts by diffusion-weighted magnetic resonance imaging
    Hyunki Kim
    Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0012, USA
    Cancer Res 68:8369-76. 2008
    ..This study supports the clinical use of DWI for pancreatic tumor patients for early assessment of drug efficacy...
  11. pmc Effect of anti-DR5 and chemotherapy on basal-like breast cancer
    Patsy G Oliver
    Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35294 2182, USA
    Breast Cancer Res Treat 133:417-26. 2012
    ..High sensitivity of basal cells to TRA-8 correlated with low expression of DR5/DDX3/cIAP1 complex. Treatment with TRA-8 and chemotherapy may be an effective therapy for basal-like breast cancer...
  12. pmc Adoptively transferred ex vivo expanded gammadelta-T cells mediate in vivo antitumor activity in preclinical mouse models of breast cancer
    Benjamin H Beck
    Department of Medicine, Division of Hematology and Oncology, University of Alabama at Birmingham, SHEL 571, 1825 University Boulevard, Birmingham, AL 35294, USA
    Breast Cancer Res Treat 122:135-44. 2010
    ..Additionally, these studies establish that clinically applicable methods for radiolabeling gammadelta-T cells allows for the tracking of adoptively transferred gammadelta-T cells in tumor-bearing hosts...
  13. pmc Breast tumor xenografts: diffusion-weighted MR imaging to assess early therapy with novel apoptosis-inducing anti-DR5 antibody
    Hyunki Kim
    Department of Radiology, University of Alabama at Birmingham, 1530 3rd Ave S, BDB 11, Birmingham, AL 35294, USA
    Radiology 248:844-51. 2008
    ..To measure the early therapeutic response to a novel apoptosis-inducing antibody, TRA-8, by using diffusion-weighted magnetic resonance (MR) imaging in a mouse breast cancer model...
  14. pmc Diffusion weighted imaging evaluated the early therapy effect of tamoxifen in an MNU-induced mammary cancer rat model
    Guihua Zhai
    The Department of Radiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA
    PLoS ONE 8:e64445. 2013
    ..To assess the optimal time point of diffusion-weighted imaging (DWI) for early prognosis of breast cancer following tamoxifen therapy using a methylnitrosourea (MNU)-induced ER-positive breast-cancer model...
  15. pmc Treatment of human colon cancer xenografts with TRA-8 anti-death receptor 5 antibody alone or in combination with CPT-11
    Patsy G Oliver
    Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama 35294 6832, USA
    Clin Cancer Res 14:2180-9. 2008
    ....
  16. pmc Early therapy assessment of combined anti-DR5 antibody and carboplatin in triple-negative breast cancer xenografts in mice using diffusion-weighted imaging and (1)H MR spectroscopy
    Guihua Zhai
    The Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Magn Reson Imaging 39:1588-94. 2014
    ..To assess the early response of triple-negative breast-cancer (TNBC) following TRA-8 and carboplatin therapy using DWI and MRS in 2LMP and SUM159 mouse models...
  17. ncbi request reprint High-resolution single-photon emission computed tomography and X-ray computed tomography imaging of Tc-99m-labeled anti-DR5 antibody in breast tumor xenografts
    Hyunki Kim
    Department of Radiology, Comprehensive Cancer Center, University of Alabama at Birmingham, 1808 7th Avenue South, Birmingham, AL 35294 0012, USA
    Mol Cancer Ther 6:866-75. 2007
    ..Imaging could provide a mechanism to assess DR5 modulation when DR5 therapy is combined with chemotherapy and radiation, and thereby aid in optimizing the dosing schedule...
  18. ncbi request reprint Antibody-based imaging strategies for cancer
    Jason M Warram
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA
    Cancer Metastasis Rev 33:809-22. 2014
    ..In this review, we will explore a wide range of antibodies and imaging modalities that are being translated to the clinic for cancer identification and surgical treatment. ..
  19. ncbi request reprint Single photon emission computed tomography demonstrated efficacy of 17β-estradiol therapy in male rats after trauma-hemorrhage and extended hypotension
    Hyunki Kim
    Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0019, USA
    J Trauma 69:1266-73. 2010
    ....